• Title/Summary/Keyword: modeling.

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Homology Modeling of Cysteinyl Leukotriene1 Receptor

  • Babu, Sathya;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.8 no.1
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    • pp.13-18
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    • 2015
  • Cysteinyl leukotrienes are inflammatory mediators having important role in pathophysiological conditions such as asthma, allergic rhinitis and have been implicated in a number of inflammatory conditions including cardiovascular and gastrointestinal diseases. Most of the disease regulatory actions of the CysLTs are mediated through CysLT1 receptor. Hence in the present study, homology modeling of CysLT1 was performed because the availability of 3D structure would enhance the development of new drugs for inflammatory diseases. However the templates identified have low sequence identity which increases the complexity of modeling. Hence, homology modeling was performed using single template, multiple templates and also using threading I-TASSER server. The best model was selected based on the validation of the generated models using Ramachandran and ERRAT plot. The model developed could be useful for identifying crucial residues and docking study.

The Effect of Television and Verbal Training on Altruistic Behavior of Preschoolers (취학전 아동의 친사회적 행동에 미치는 TV 및 언어적 훈련의 효과)

  • Woo, Hee Chung;Chung, Ock Boon
    • Korean Journal of Child Studies
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    • v.11 no.1
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    • pp.87-99
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    • 1990
  • The present study was designed to investigate the effect of altruistic TV viewing and verbal training on the altruistic behavior of preschoolers. The subjects of this study were a total of 56 boys and 57 girls from a kindergarten in Kwachon, Kyung-gi do. The subjects were assigned to one of three conditions: in the first condition subjects were shown video tapes designed to portray prosocial themes (TV modeling group) ; in the second condition subjects saw the video tapes in addition to verbal training (TV modeling plus verbal training group); in the third condition subjects received neither TV modeling nor verbal training (control group). Statistical analysis was by ANOVA and $Scherr\acute{e}$ test. Significant differences were found in altruistic behavior between the TV modeling and the TV modeling with verbal training groups.

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A Study on the Application of Workstation Modeling (워크스테이션 모델링 활용에 관한 연구)

  • 김낙권;김현성
    • Archives of design research
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    • v.13
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    • pp.83-91
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    • 1996
  • In this paper, proposed through the development process of a VCR the process of making exact three-dimensional modeling data using the Alias-one of the popular workstation in product design development process. At first, the features of the NURBS curve which is the basic curve in the modeling of Alias system and the methods of building surface are reviewed. The methods of rendering, lighting and textures are reviewed for application of realistic image presentation after building basic surfaces. The synthetic application methode of these factors necessary for the product design modeling is presented through the development process of a VCR.

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Empirical Modeling on the Breaking Characteristics of Power Current Limited Fuse (전력용 백업퓨우즈 차단특성 모델링)

  • Lee Sei-Hyun;Lee Bvung-Sung;Han Sang-Ok
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.54 no.9
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    • pp.391-396
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    • 2005
  • In this paper the modeling of interrupting characteristics of a high voltage current limiting fuse to be used in a power distribution system is introduced. In order to reduce the level of energy which can be absorbed by equipment during fault current flow, a high voltage current limiting fuse can generate a high voltage at the fuse terminals. Consequently it is necessary to model and analyze precisely the voltage and current variation during a CL fuse action. The characteristics of CL fuse operation modeled by electrical components have been performed with less than 6 [$\%$] errors. So the fuse designer or manufacturer can estimate the characteristics of CL fuse operation by using this modeling. The Electro Magnetic Transient Program (EMTP) is used to develop the modeling.

A Study on Modeling of Search Space with GA Sampling

  • Banno, Yoshifumi;Ohsaki, Miho;Yoshikawa, Tomohiro;Shinogi, Tsuyoshi;Tsuruoka, Shinji
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2003.09a
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    • pp.86-89
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    • 2003
  • To model a numerical problem space under the limitation of available data, we need to extract sparse but key points from the space and to efficiently approximate the space with them. This study proposes a sampling method based on the search process of genetic algorithm and a space modeling method based on least-squares approximation using the summation of Gaussian functions. We conducted simulations to evaluate them for several kinds of problem spaces: DeJong's, Schaffer's, and our original one. We then compared the performance between our sampling method and sampling at regular intervals and that between our modeling method and modeling using a polynomial. The results showed that the error between a problem space and its model was the smallest for the combination of our sampling and modeling methods for many problem spaces when the number of samples was considerably small.

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On the Organization of Object-Oriented Model Bases for Structured Modeling (구조적 모델링을 위한 객체지향적 모델베이스 조직화)

  • 정대율
    • The Journal of Information Systems
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    • v.5
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    • pp.149-173
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    • 1996
  • This paper focus on the development of object-oriented model bases for Structured Modeling. For the model base organization, object modeling techniques and model typing concept which is similar to data typing concept are used. Structured modeling formalizes the notion of a definitional system as a way of dscribing models. From the object-oriented concept, a structured model can be represented as follows. Each group of similar elements(genus) is represented by a composite class. Other type of genera can be represented in a similar manner. This hierarchical class composition gives rise to an acyclic class-composition graph which corresponds with the genus graph of structured model. Nodes in this graph are instantiated to represent the elemental graph for a specific model. Taking this class composition process one step further, we aggregate the classes into higher-level composite classes which would correspond to the structured modeling notion of a module. Finally, the model itself is then represented by a composite class having attributes each of whose domain is a composite class representing one of the modules. The resulting class-composition graph represent the modular tree of the structured.

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Implementation of Emotional Model of Software Robot Using the Sensor Modules for External Environments (외부 환경 감지 센서 모듈을 이용한 소프트웨어 로봇의 감정 모델 구현)

  • Lee, Joon-Yong;Kim, Chang-Hyun;Lee, Ju-Jang
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2005.11a
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    • pp.179-184
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    • 2005
  • Recently, studying on modeling the emotion of a robot has become issued among fields of a humanoid robot and an interaction of human and robot. Especially, modeling of the motivation, the emotion, the behavior, and so on, in the robot, is hard and need to make efforts to use our originality. In this paper, new modeling using mathematical formulations to represent the emotion and the behavior selection is proposed for the software robot with virtual sensor modules. Various Points which affect six emotional states such as happy or sad are formulated as simple exponential equations with various parameters. There are several experiments with seven external sensor inputs from virtual environment and human to evaluate this modeling.

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A Study on Improving the predict accuracy rate of Hybrid Model Technique Using Error Pattern Modeling : Using Logistic Regression and Discriminant Analysis

  • Cho, Yong-Jun;Hur, Joon
    • Journal of the Korean Data and Information Science Society
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    • v.17 no.2
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    • pp.269-278
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    • 2006
  • This paper presents the new hybrid data mining technique using error pattern, modeling of improving classification accuracy. The proposed method improves classification accuracy by combining two different supervised learning methods. The main algorithm generates error pattern modeling between the two supervised learning methods(ex: Neural Networks, Decision Tree, Logistic Regression and so on.) The Proposed modeling method has been applied to the simulation of 10,000 data sets generated by Normal and exponential random distribution. The simulation results show that the performance of proposed method is superior to the existing methods like Logistic regression and Discriminant analysis.

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Prediction of Transmembrane Protein Topology Using Position-specific Modeling of Context-dependent Structural Regions

  • Chi, Sang-Mun
    • Journal of the Korean Data and Information Science Society
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    • v.16 no.3
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    • pp.683-693
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    • 2005
  • This paper presents a new transmembrane Protein topology prediction method which is an attempt to model the topological rules governing the topogenesis of transmembrane proteins. Context-dependent structural regions of the transmembrane protein are used as basic modeling units in order to effectively represent their topogenic roles during transmembrane protein assembly. These modeling units are modeled by means of a tied-state hidden Markov model, which can express the position-specific effect of amino acids during ransmembrane protein assembly. The performance of prediction improves with these modeling approaches. In particular, marked improvement of orientation prediction shows the validity of the proposed modeling. The proposed method is available at http://bioroutine.com/TRAPTOP.

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Research about Graphic Modeling Element of Media Skin (미디어스킨 기반의 그래픽 조형 요소에 관한 연구)

  • Kim, Moon Seok;Oh, Moon Seok
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.6 no.3
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    • pp.151-158
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    • 2010
  • Media Skin is in form extended of TV or computer monitor that is digital media picture or digital output of graphic. Mean reflex or graphics applied in LCD Window of portable phone or LED display etc. of city environment mainly. Draft and study skill development trend and studied about role as graphic modeling to Media Skin. Media Skin that inflect LED over inside and outside of the country impulse to steal current is embodied. It is situating from modern society to one media trend. Progressed general investigation about Media Skin's connection skill in research. As culture contents progressed determinate research to graphic modeling element etc. As graphic modeling of new media special quality is construed by 4 as following. Contact, Real time, Nonlinear, Multi-Communication are it. Media Skin has function as symbol of city or media construction facade. Also, have enough value as function new media as information offer function, art.