• 제목/요약/키워드: modeling of structures

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설비공학 분야의 최근 연구 동향 : 2013년 학회지 논문에 대한 종합적 고찰 (Recent Progress in Air-Conditioning and Refrigeration Research : A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2013)

  • 이대영;김사량;김현정;김동선;박준석;임병찬
    • 설비공학논문집
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    • 제26권12호
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    • pp.605-619
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    • 2014
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2013. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. Conclusions are as follows. (1) The research works on the thermal and fluid engineering have been reviewed as groups of fluid machinery, pipes and relative parts including orifices, dampers and ducts, fuel cells and power plants, cooling and air-conditioning, heat and mass transfer, two phase flow, and the flow around buildings and structures. Research issues dealing with home appliances, flows around buildings, nuclear power plant, and manufacturing processes are newly added in thermal and fluid engineering research area. (2) Research works on heat transfer area have been reviewed in the categories of heat transfer characteristics, pool boiling and condensing heat transfer and industrial heat exchangers. Researches on heat transfer characteristics included the results for general analytical model for desiccant wheels, the effects of water absorption on the thermal conductivity of insulation materials, thermal properties of Octadecane/xGnP shape-stabilized phase change materials and $CO_2$ and $CO_2$-Hydrate mixture, effect of ground source heat pump system, the heat flux meter location for the performance test of a refrigerator vacuum insulation panel, a parallel flow evaporator for a heat pump dryer, the condensation risk assessment of vacuum multi-layer glass and triple glass, optimization of a forced convection type PCM refrigeration module, surface temperature sensor using fluorescent nanoporous thin film. In the area of pool boiling and condensing heat transfer, researches on ammonia inside horizontal smooth small tube, R1234yf on various enhanced surfaces, HFC32/HFC152a on a plain surface, spray cooling up to critical heat flux on a low-fin enhanced surface were actively carried out. In the area of industrial heat exchangers, researches on a fin tube type adsorber, the mass-transfer kinetics of a fin-tube-type adsorption bed, fin-and-tube heat exchangers having sine wave fins and oval tubes, louvered fin heat exchanger were performed. (3) In the field of refrigeration, studies are categorized into three groups namely refrigeration cycle, refrigerant and modeling and control. In the category of refrigeration cycle, studies were focused on the enhancement or optimization of experimental or commercial systems including a R410a VRF(Various Refrigerant Flow) heat pump, a R134a 2-stage screw heat pump and a R134a double-heat source automotive air-conditioner system. In the category of refrigerant, studies were carried out for the application of alternative refrigerants or refrigeration technologies including $CO_2$ water heaters, a R1234yf automotive air-conditioner, a R436b water cooler and a thermoelectric refrigerator. In the category of modeling and control, theoretical and experimental studies were carried out to predict the performance of various thermal and control systems including the long-term energy analysis of a geo-thermal heat pump system coupled to cast-in-place energy piles, the dynamic simulation of a water heater-coupled hybrid heat pump and the numerical simulation of an integral optimum regulating controller for a system heat pump. (4) In building mechanical system research fields, twenty one studies were conducted to achieve effective design of the mechanical systems, and also to maximize the energy efficiency of buildings. The topics of the studies included heating and cooling, HVAC system, ventilation, and renewable energies in the buildings. Proposed designs, performance tests using numerical methods and experiments provide useful information and key data which can improve the energy efficiency of the buildings. (5) The field of architectural environment is mostly focused on indoor environment and building energy. The main researches of indoor environment are related to infiltration, ventilation, leak flow and airtightness performance in residential building. The subjects of building energy are worked on energy saving, operation method and optimum operation of building energy systems. The remained studies are related to the special facility such as cleanroom, internet data center and biosafety laboratory. water supply and drain system, defining standard input variables of BIM (Building Information Modeling) for facility management system, estimating capability and providing operation guidelines of subway station as shelter for refuge and evaluation of pollutant emissions from furniture-like products.

비무장지대 출토 군화의 형태 복원을 위한 3차원 디지털 기술의 적용 및 보존처리 (Application and conservation of 3D technology for the restoration of the original shape of military boots excavated in the DMZ)

  • 오승준;위광철
    • 헤리티지:역사와 과학
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    • 제56권2호
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    • pp.124-133
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    • 2023
  • 국방부 유해발굴단을 통해 발굴된 한국전쟁 전사자 유품의 보존 방법론을 제시하고자 3D 기술의 적용과 가역성 및 안정성이 우수한 보존 재료를 이용해 군화류 2점에 대한 보존처리를 진행하였다. 3D 스캐닝과 모델링을 통해 군화를 신었던 전사자의 발 사이즈를 추정해 볼 수 있었으며, 이를 기반으로 3D 출력 구조체를 이용해 원형을 복원하였다. 원형 복원은 출토 유품의 오염물 제거와 유연제 처리 작업을 거쳐 구조체의 형태로 복원하였으며, 열화되어 찢겨지거나 멸실된 부분은 접합 및 메움처리 후 고색처리를 통해 원형을 복원하였다. 보존처리 후 2종의 군화 모두 밑창과 발등 부분은 고무류, 발등 일부와 발목 부분은 합성가죽류로 제작된 것을 확인할 수 있었으며, 이는 방수 또는 방한의 목적으로 제작되어 1944년에 도입된 모델 Shoe Pac(M-1944, 12-inch) 방한화와 유사한 군화임을 확인하였다. 이러한 결과는 보존처리를 통해 출토된 유품의 제작기법과 재질, 용도 등을 밝혀낼 수 있음을 확인한 연구로서 과학적 보존처리와 3D 기술의 융합적 연구의 중요성을 보여준 사례이다.

Wind-sand coupling movement induced by strong typhoon and its influences on aerodynamic force distribution of the wind turbine

  • Ke, Shitang;Dong, Yifan;Zhu, Rongkuan;Wang, Tongguang
    • Wind and Structures
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    • 제30권4호
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    • pp.433-450
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    • 2020
  • The strong turbulence characteristic of typhoon not only will significantly change flow field characteristics surrounding the large-scale wind turbine and aerodynamic force distribution on surface, but also may cause morphological evolution of coast dune and thereby form sand storms. A 5MW horizontal-axis wind turbine in a wind power plant of southeastern coastal areas in China was chosen to investigate the distribution law of additional loads caused by wind-sand coupling movement of coast dune at landing of strong typhoons. Firstly, a mesoscale Weather Research and Forecasting (WRF) mode was introduced in for high spatial resolution simulation of typhoon "Megi". Wind speed profile on the boundary layer of typhoon was gained through fitting based on nonlinear least squares and then it was integrated into the user-defined function (UDF) as an entry condition of small-scaled CFD numerical simulation. On this basis, a synchronous iterative modeling of wind field and sand particle combination was carried out by using a continuous phase and discrete phase. Influencing laws of typhoon and normal wind on moving characteristics of sand particles, equivalent pressure distribution mode of structural surface and characteristics of lift resistance coefficient were compared. Results demonstrated that: Compared with normal wind, mesoscale typhoon intensifies the 3D aerodynamic distribution mode on structural surface of wind turbine significantly. Different from wind loads, sand loads mainly impact on 30° ranges at two sides of the lower windward region on the tower. The ratio between sand loads and wind load reaches 3.937% and the maximum sand pressure coefficient is 0.09. The coupling impact effect of strong typhoon and large sand particles is more significant, in which the resistance coefficient of tower is increased by 9.80% to the maximum extent. The maximum resistance coefficient in typhoon field is 13.79% higher than that in the normal wind field.

Dynamic analysis of slack moored spar platform with 5 MW wind turbine

  • Seebai, T.;Sundaravadivelu, R.
    • Ocean Systems Engineering
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    • 제1권4호
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    • pp.285-296
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    • 2011
  • Spar platforms have several advantages for deploying wind turbines in offshore for depth beyond 120 m. The merit of spar platform is large range of topside payloads, favourable motions compared to other floating structures and minimum hull/deck interface. The main objective of this paper is to present the response analysis of the slack moored spar platform supporting 5MW wind turbine with bottom keel plates in regular and random waves, studied experimentally and numerically. A 1:100 scale model of the spar with sparD, sparCD and sparSD configuration was studied in the wave basin ($30{\times}30{\times}3m$) in Ocean engineering department in IIT Madras. In present study the effect of wind loading, blade dynamics and control, and tower elasticity are not considered. This paper presents the details of the studies carried out on a 16 m diameter and 100 m long spar buoy supporting a 90 m tall 5 MW wind turbine with 3600 kN weight of Nacelle and Rotor and 3500 kN weight of tower. The weight of the ballast and the draft of the spar are adjusted in such a way to keep the centre of gravity below the centre of buoyancy. The mooring lines are divided into four groups, each of which has four lines. The studies were carried out in regular and random waves. The operational significant wave height of 2.5 m and 10 s wave period and survival significant wave height of 6 m and 18 s wave period in 300 m water depth are considered. The wind speed corresponding to the operational wave height is about 22 knots and this wind speed is considered to be operating wind speed for turbines. The heave and surge accelerations at the top of spar platform were measured and are used for calculating the response. The geometric modeling of spar was carried out using Multisurf and this was directly exported to WAMIT for subsequent hydrodynamic and mooring system analysis. The numerical results were compared with experimental results and the comparison was found to be good. Parametric study was carried out to find out the effect of shape, size and spacing of keel plate and from the results obtained from present work ,it is recommended to use circular keel plate instead of square plate.

Machinability investigation and sustainability assessment in FDHT with coated ceramic tool

  • Panda, Asutosh;Das, Sudhansu Ranjan;Dhupal, Debabrata
    • Steel and Composite Structures
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    • 제34권5호
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    • pp.681-698
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    • 2020
  • The paper addresses contribution to the modeling and optimization of major machinability parameters (cutting force, surface roughness, and tool wear) in finish dry hard turning (FDHT) for machinability evaluation of hardened AISI grade die steel D3 with PVD-TiN coated (Al2O3-TiCN) mixed ceramic tool insert. The turning trials are performed based on Taguchi's L18 orthogonal array design of experiments for the development of regression model as well as adequate model prediction by considering tool approach angle, nose radius, cutting speed, feed rate, and depth of cut as major machining parameters. The models or correlations are developed by employing multiple regression analysis (MRA). In addition, statistical technique (response surface methodology) followed by computational approaches (genetic algorithm and particle swarm optimization) have been employed for multiple response optimization. Thereafter, the effectiveness of proposed three (RSM, GA, PSO) optimization techniques are evaluated by confirmation test and subsequently the best optimization results have been used for estimation of energy consumption which includes savings of carbon footprint towards green machining and for tool life estimation followed by cost analysis to justify the economic feasibility of PVD-TiN coated Al2O3+TiCN mixed ceramic tool in FDHT operation. Finally, estimation of energy savings, economic analysis, and sustainability assessment are performed by employing carbon footprint analysis, Gilbert approach, and Pugh matrix, respectively. Novelty aspects, the present work: (i) contributes to practical industrial application of finish hard turning for the shaft and die makers to select the optimum cutting conditions in a range of hardness of 45-60 HRC, (ii) demonstrates the replacement of expensive, time-consuming conventional cylindrical grinding process and proposes the alternative of costlier CBN tool by utilizing ceramic tool in hard turning processes considering technological, economical and ecological aspects, which are helpful and efficient from industrial point of view, (iii) provides environment friendliness, cleaner production for machining of hardened steels, (iv) helps to improve the desirable machinability characteristics, and (v) serves as a knowledge for the development of a common language for sustainable manufacturing in both research field and industrial practice.

CMIP5 및 CMIP6 GCM 기반 무한천 유역 농경지 미래 침수 위험도 분석 (Future Inundation Risk Evaluation of Farmland in the Moohan Stream Watershed Based on CMIP5 and CMIP6 GCMs)

  • 전상민;황순호;김지혜;곽지혜;김계웅;이현지;김석현;조재필;이재남;강문성
    • 한국농공학회논문집
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    • 제62권6호
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    • pp.131-142
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    • 2020
  • The objective of this study was to evaluate future inundation risk of farmland according to the application of coupled model intercomparison project phase 5 (CMIP5) and coupled model intercomparison project phase 6 (CMIP6). In this study, future weather data based on CMIP5 and CMIP6 general circulation model (GCM) were collected, and inundation was simulated using the river modeling system for small agricultural watershed (RMS) and GATE2018 in the Tanjung district of the Moohan stream watershed. Although the average probable rainfall of CMIP5 and CMIP6 did not show significant differences as a result of calculating the probability rainfall, the difference between the minimum and maximum values was significantly larger in CMIP6. The results of the flood discharge calculation and the inundation risk assessment showed similar to trends to those of probability rainfall calculations. The risk of inundation in the future period was found to increase in all sub-watersheds, and the risk of inundation has been analyzed to increase significantly, especially if CMIP6 data are used. Therefore, it is necessary to consider climate change effects by utilizing CMIP6-based future weather data when designing and reinforcing water structures in agricultural areas in the future. The results of this study are expected to be used as basic data for utilizing CMIP6-based future weather data.

Molecular Docking Study of Aminoacyl-tRNA Synthetases with Ligand Molecules from Four Different Scaffolds

  • Bharatham, Nagakumar;Bharatham, Kavitha;Lee, Yu-No;Kim, Song-Mi;Lazar, Prettina;Baek, A-Young;Park, Chan-In;Eum, Hee-Sung;Ha, Hyun-Joon;Yun, Sae-Young;Lee, Won-Koo;Kim, Sung-Hoon;Lee, Keun-Woo
    • Bulletin of the Korean Chemical Society
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    • 제31권3호
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    • pp.606-610
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    • 2010
  • Aminoacyl-tRNA synthetases (aaRSs) play vital roles in protein biosynthesis of living organisms and are interesting antibacterial drug targets. In order to find out new inhibitor candidate molecules as antibacterial agent, the binding modes of the candidate molecules were investigated at the active sites of aaRSs by molecular docking study. The docking simulations were performed with 48 compounds from four different scaffolds into the eight different aaRSs. The results show that scaffolds 3 and 4 compounds have consistently better binding capabilities, specifically for HisRS (E. coli) and IleRS (S. aureus). The binding modes of the best compounds with the proteins were well compatible with those of two ligands in crystal structures. Therefore, we expect that the final compounds we present may have reasonable aaRS inhibitory activity.

T-세포 항원 수용체 매개 신호전달 조절자로서 돼지 CD45RO 구조특성 (Key Structural Features of PigCD45RO as an Essential Regulator of T-cell Antigen Receptor Signaling)

  • 채한화;임다정
    • 한국산학기술학회논문지
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    • 제20권9호
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    • pp.211-226
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    • 2019
  • 백혈구 공통 항원인 돼지 CD45는 PTPRC 유전자에 암호화 되어 있으며, CD45엑손의 선택적 스플라이싱에 따라 다른 T-세포에서 발현되는 티로신 인산분해효소이다. CD45는 기질인 TCR의 $CD3{\zeta}$ 사슬, Lck, Fyn, Zap-70 kinase의 인산화된 티로신에서 인산을 분해하여 T-세포 항원 수용체(TCR) 매개 신호전달을 조절한다. CD45의 조절이상은 많은 면역 질환과 관련이 있어서, CD45는 면역약물 개발에 표적이 되어왔다. TCR 신호전달의 조절효과를 가진 주요 구조적 특징을 특성화하기 위해, 사람의 알려진 CD45 구조를 템플릿으로 적용하여 돼지 CD45RO(가장 작은 CD45 isoform)의 단백질 구조와 예측된 돼지 CD45RO 모델구조에 $CD3{\zeta}$ 사슬의 ITAM(REEpYDV)를 도킹하여 CD45RO/ITAM 펩타이드 결합구조를 예측하였다. 돼지 CD45RO의 구조적 특징은 세포외영역의 구조견고성과 세포질 내 티로신 인산분해효소 도메인의 KNRY와 PTP signature 기능모티프(두 기능 모티프는 ITAM 펩타이드 결합부위의 좁은 입구로 역할)에 있었다. 주요 구조특성은 돼지 CD45RO-ITAM 펩타이드 결합구조 안정성과 결합친화력을 조절하면서 기질 선택성에 영향을 준다. 돼지 CD45RO의 구조적 특성은 T-세포에 특이적인 면역 조절제를 탐색하는 데에 적용될 것이다.

Observation of behavior of the Ahlat Gravestones (TURKEY) at seismic risk and their recognition by QR code

  • Isik, Ercan;Antep, Baris;Buyuksarac, Aydin;Isik, Mehmet Fatih
    • Structural Engineering and Mechanics
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    • 제72권5호
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    • pp.643-652
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    • 2019
  • Protection of cultural heritage and carrying it to the future are at the top of the significant topics of research and implementation in engineering in the 21st century. There are several historical structures in the district of Ahlat located in the east of Turkey on the Lake Van Basin that has harbored many civilizations. Some of such works are the gravestones that are found in the Ahlat Seljuk Cemetery, which is the oldest and largest cemetery in the district. This study firstly provides information about the Ahlat Seljuk Cemetery and the gravestones found in it. Observation-based structural analyses were carried out on these gravestones that are found in this area that are known to have belonged to different civilizations based on their physical and constructional characteristics. These stones were built out of Ahlat stone as single pieces. Information is provided on the damages that have occurred on the gravestones in time and their causes. In general, losses of mass, abrasions, separations, collapses and calcifications due to natural conditions, as well as vegetative formations, were observed in the gravestones. To provide an example of other gravestones within the context of the study, the gravestone that is known to belong to the person named Nureddin Ebu Hasan was selected. As a result of the modeling that was carried out for this gravestone by using the finite elements method, modal analyses were carried out. With these analyses, for the gravestone, period, effective mass participation rates and stress values were calculated. The stress values that were obtained in this study were compared to the material safety stress values that were obtained in previous studies. Additionally, QR code application was created for the gravestone that was selected as an example in the study, and information on this gravestone was transferred to an electronic environment. The QR code application includes different language options, visuals of the gravestone and information on the gravestone. The QR application was also supported with a video of the cemetery where the gravestone is located. With this application, access to information about gravestones will be possible by using tablets and smartphones. With a QR code to be created for each gravestone, these gravestones will obtain identity cards.

Impact of RGD Peptide Tethering to IL24/mda-7 (Melanoma Differentiation Associated Gene-7) on Apoptosis Induction in Hepatocellular Carcinoma Cells

  • Bina, Samaneh;Shenavar, Fatemeh;Khodadad, Mahboobeh;Haghshenas, Mohammad Reza;Mortazavi, Mojtaba;Fattahi, Mohammad-Reza;Erfani, Nasrollah;Hosseini, Seyed Younes
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권14호
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    • pp.6073-6080
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    • 2015
  • Background: Melanoma differentiation-associated gene-7 (MDA-7)/interleukin-24 (IL-24), a unique tumor suppressor gene, has killing activity in a broad spectrum of cancer cells. Herein, plasmids producing mda-7 proteins fused to different RGD peptides (full RGD4C and shortened RGD, tRGD) were evaluated for apoptosis induction with a hepatocellular carcinoma cell line, Hep-G2. The study aim was to improve the apoptosis potency of mda-7 by tethering to RGD peptides. Materials and Methods: Three plasmids including mda-7, mda-7-RGD and mda-7-tRGD genes beside a control vector were transfected into Hep-G2 cells. After 72 hours incubation, cell viability was evaluated by MTT assay. In addition, the rate of apoptosis was analyzed by flow cytometry using PI/annexin staining. To detect early events in apoptosis, 18 hours after transfection, expression of the BAX gene was quantified by real time PCR. Modeling of proteins was also performed to extrapolate possible consequences of RGD modification on their structures and subsequent attachment to receptors. Results and Conclusions: In MTT assays, while all mda-7 forms showed measurable inhibition of proliferation, unmodified mda-7 protein exhibited most significant effect compared to control plasmid (P<0.001). Again, flow cytometry analysis showed a significant apoptosis induction by simple mda-7 gene but not for those RGD-fused mda-7 proteins. These findings were also supported by expression analysis of BAX gene (P<0.001). Protein modelling analysis revealed that tethering RGD at the end of IL-24/Mda7 disrupt attachment to cognate receptor, IL-20R1/IL-20R2. In conclusion, fusion of RGD4C and shortened RGD peptides to carboxyl terminal of mda7, not only reduce apoptosis property in vitro but also disrupt receptor attachment as demonstrated by protein modelling.