• Title/Summary/Keyword: mixed state

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Controlling Factors of Feed Intake and Salivary Secretion in Goats Fed on Dry Forage

  • Sunagawa, K.;Ooshiro, T.;Nakamura, N.;Nagamine, I.;Shiroma, S.;Shinjo, A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.10
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    • pp.1414-1420
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    • 2005
  • The purpose of this research was to determine whether or not feeding induced hypovolemia (decreases in plasma volume) and decreases in plasma bicarbonate concentration caused by loss of $NaHCO_3$ from the blood, act to suppress feed intake and saliva secretion volumes during the initial stages of feeding in goats fed on dry forage. The animals were fed twice a day at 10:30 and at 16:00 for 2 h each time. Prior to the morning feeding, the collected saliva (3-5 kg) was infused into the rumen. During the morning 2 h feeding period (10:30 to 12:30), the animals were fed 2-3 kg of roughly crushed alfalfa hay cubes. At 16:00, the animals were fed again with 0.8 kg of alfalfa hay cubes, 200 g of commercial ground concentrate and 20 g of sodium bicarbonate. In order to compensate for water or $NaHCO_3$ lost through saliva during initial stages of feeding, a 3 h intravenous infusion (17-19 ml/min) of artificial mixed saliva (ASI) or mannitol solution (MI) was begun 1 h prior to the morning feeding and continued until the conclusion of the 2 h feeding period. The physiological state of the goats in the present experiment remained unchanged after parotid gland fistulation. Circulating plasma volume decreases caused by feeding (estimated by increases in plasma total protein concentration) were significantly suppressed by the ASI and MI treatments. During the first 1 h of the 2 h feeding period, plasma osmolality in the ASI treatment was the same as the NI (non-infusion control) treatment, while plasma osmolality in the MI treatment was significantly higher. In comparison to the NI treatment, cumulative feed intake levels for the duration of the 2 h feeding period in the ASI and MI treatments increased markedly by 56.6 and 88.3%, respectively. On the other hand, unilateral cumulative parotid saliva secretion volume following the termination of the 2 h feeding period in the ASI treatment was 50.7% higher than that in the NI treatment. MI treatment showed the same level as the NI treatment. The results of the present experiment proved that the humoral factors involved in the suppression of feeding and saliva secretion during the initial stages of feeding in goats fed on dry forage, are feeding induced hypovolemia and decrease in plasma $HCO_3^-$ concentration caused by loss of $NaHCO_3$ from the blood.

Clinical and Symptomatic Correlates of Alexithymia in Schizophrenia (정신분열병의 감정표현 불능증과 관련된 임상 및 증상 요인)

  • Lee, Kyung-Ha;Kim, Dae-Ho;Roh, Sung-Won;Nam, Jeong-Hyun
    • Korean Journal of Psychosomatic Medicine
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    • v.13 no.1
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    • pp.32-40
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    • 2005
  • Objectives : This study looked at the symptoms of alexithymia in schizophrenia and their association with clinical variables and schizophrenic symptomatology. Methods Consecutive fifty eight inpatients with DSM-IV diagnoses of schizophrenia completed 26item version of Toronto Alexithymia Scale (TAS), Symptom Checklist-90-Revised(SCL-90-R), and Positive and Negative Syndrome Scale(PANSS). Results : Authors did not find any correlation between scores of PANSS and TAS. However, all the subscale scores of SCL-90-R were significantly correlated with total score of TAS. Also, 'difficulty identifying and deistinguishing between feelings and bodily sensations' and 'difficulty describing feelings' significantly correlated with SCL-90-R subscale scores. 'Reduced daydreaming' had mixed findings and 'externally oriented thinking' did not correlate. Multiple regression model included Global Severity Index of SCL-90-R accounting 28.2% of variance for TAS scores. Conclusion : These findings together with discrepancy in results between objective and subjective tests suggest that alexithymia in schizophrenia may have two constructs, 'difficulty to describe and communicate feelings(state)' and 'externally oriented thinking(trait)' Authors suggest further study needs to confirm construct validity of TAS in this population.

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Application of Statistical Analysis for Optimization of Organic Wastes Acidogenesis (유기성 폐기물의 산발효 최적화를 위한 통계학적 분석 방안의 적용)

  • Jeong, Emma;Kim, Hyun-Woo;Nam, Joo-Youn;Oh, Sae-Eun;Hong, Seung-Mo;Shin, Hang-Sik
    • Journal of Korean Society of Environmental Engineers
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    • v.30 no.8
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    • pp.781-788
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    • 2008
  • This study shows how to find out optimum co-substrate conditions and continuous operating parameters for maximum acidification of three different organic wastes - livestock wastewater, sewage sludge and food waste. Design of experiments and statistical analysis were revealed as appropriate optimization schemes in this study. Analyses of data obtained from batch tests demonstrated the optimum substrate mixing ratio, which was determined by maximum total volatile fatty acids(TVFA) increase and soluble chemical oxygen demand(SCOD) increase simultaneously. Suggested optimum mixing ratio of livestock wastewater, sewage sludge and food waste was 0.4 : 1.0 : 1.1 based on COD, respectively. Response surface methodology(RSM) contributed to find out optimum operating parameter - hydraulic retention time(HRT) and substrate concentration - for the semi-continuous acidogenic fermentation of mixed organic wastes. The optimum condition for maximum TVFA increase was 2 days of HRT and 29,237 mg COD/L. Empirical equations obtained through regression analysis could predict that TVFA increase would be 73%. To confirm the validity of the statistical experimental strategies, a confirmation experiment was conducted under the obtained optimum conditions, and relative error between theoretical and experimental results was within 4%. This result reflects that using statistical and RSM technique can be effectively used for the optimization of real waste treatment processes.

Study on Conversion of Carbon Dioxide to Methyl Alcohol over Ceramic Monolith Supported CuO and ZnO Catalysts (세라믹 모노리스에 담지된 CuO와 ZnO계 촉매에 의한 이산화탄소의 메탄올로의 전환에 관한 연구)

  • Park, Chul-Min;Ahn, Won-Ju;Jo, Woong-Kyu;Song, Jin-Hun;Kim, Ki-Joong;Jeong, Woon-Jo;Sohn, Bo-Kyun;Ahn, Byeong Kwon;Chung, Min-Chul;Park, Kwon-Pil;Ahn, Ho-Geun
    • Journal of Korean Society for Atmospheric Environment
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    • v.29 no.1
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    • pp.97-104
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    • 2013
  • Methyl alcohol is one of the basic intermediates in the chemical industry and is also being used as a fuel additive and as a clean burning fuel. In this study, conversion of carbon dioxide to methyl alcohol was investigated using catalytic chemical methods. Ceramic monoliths (M) with $400cell/in^2$ were used as catalyst supports. Monolith-supported CuO-ZnO catalysts were prepared by wash-coat method. The prepared catalysts were characterized by using ICP analysis, TEM images and XRD patterns. The catalytic activity for carbon dioxide hydrogenation to methyl alcohol was investigated using a flow-type reactor under various reaction temperature, pressure and contact time. In the preparation of monolith-supported CuO-ZnO catalysts by wash-coat method, proper concentration of precursors solution was 25.7% (w/v). The mixed crystal of CuO and ZnO was well supported on monolith. And it was known that more CuO component may be supported than ZnO component. Conversion of carbon dioxide was increased with increasing reaction temperature, but methyl alcohol selectivity was decreased. Optimum reaction temperature was about $250^{\circ}C$ under 20 atm because of the reverse water gas shift reaction. Maximum yield of methyl alcohol over CuO-ZnO/M catalyst was 5.1 mol% at $250^{\circ}C$ and 20 atm.

A Study on Physical Dispersion and Chemical Modification of Graphene (Graphene의 물리적 분산과 화학적 표면 개질 연구)

  • Yim, Eun-Chae;Kim, Seong-Jun
    • Korean Chemical Engineering Research
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    • v.53 no.6
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    • pp.792-797
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    • 2015
  • Graphene has a wide spectrum on its application field due to various and excellent physical properties. However, it is very difficult to apply that graphene exists as lump or fold condition in general organic solvents. Besides, graphene was difficult to maintain as uniform condition due to chemical inert and distributions with various size and shapes. Therefore, this study was focused to study dispersion and modifying methods of aggregated graphene. The dispersion methods contain as follow: i) physical milling using glass bead, ii) co-treatment of glass bead and ultrasonic waves, iii) dispersion in organic solvents, iv) modifying with dry-ice. Milling using glass bead with size 2.5 mm was effective to be size decrease of 36.4% in comparison with control group. Mixed treatment of glass bead (size 2.5 mm) and ultrasonic waves (225W, 10 min) showed relative size decrease of 76%, suggesting that the size decrease depends on the size of glass bead, intensity of ultrasonic waves and treatment time. Solvents of Ethyl acetate (EA) and Isoprophyl alcohol (IPA) were used in order to improve dispersion by modifying surface of graphene. IPA of them showed a favorable dispersion with more -CO functional groups in the FT-IR analysis. On the other hand, the oxygen content of graphene surface modified by dry-ice was highly increased from 0.8 to 4.9%. From the results, it was decided that the favorable dispersion state for a long time was obtained under the condition of -CO functional group increase in IPA solvent.

Do Foreign Firms Really Pay Higher Wages Than Local Ones? (외국계 기업이 국내기업보다 실제로 임금을 더 많이 주는가?)

  • Choi, Minsik
    • Journal of Labour Economics
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    • v.29 no.3
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    • pp.1-23
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    • 2006
  • This study investigates the effects of inward foreign direct investment on local workers' wages by focusing on U.S. manufacturing industries for the period from 1987 to 1992. Contrary to public perception that foreign ownership is positively associated with higher wages, previous studies show mixed results. Since most of the previous studies used industry or firm level average wages, they can not control for the impact of individual characteristics on wages. I use two different approaches to control individual characteristics and to implement estimation in this study: (1) One-step estimation with industry-state level of inward foreign direct investments by using individual level data, and (2) Two-step industry characteristic regression approach. The higher presence of foreign firms is associated with higher local wages after workers' observable characteristics are controlled for in the first approach. This effect, however, disappears once workers' industry affiliations and regions are controlled for in cross-section analysis. In a panel data analysis, I did not find any statistically significant positive association between inward FDI activities and industry wage premiums within industry. Further, inward FDI activities appeared to be negatively associated with worker's industry wage premium for workers with more than high school education.

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Degradation characteristics in anaerobic co-digestion of sewage sludge and food waste (하수슬러지와 음식물쓰레기의 혼합소화시 혼합비율과 기질농도에 따른 분해특성)

  • Shin, Hang-Sik;Kim, Hyun-Woo;Han, Sun-Kee;Kang, Seok-Tae
    • Journal of the Korea Organic Resources Recycling Association
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    • v.10 no.1
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    • pp.96-101
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    • 2002
  • This research was conducted to find the optimal condition in codigestion of food waste and sewage sludge with various mixing ratios. The analysis of degradation characteristics were based on the variations of methane production as well as methane production rate (MPR). BMP values were getting higher as the addition of foodwaste increased. But the lag-phase were prolonged when the foodwaste was over 40%, Nonlinear regression was conducted with the cumulative methane production data. Not only thermophilic but mesophilic condition, 40% of foodwaste addition showed maximum MPR. Higher mixing ratio which is over 50% were unprofitable in gaining higher MPR values. The most important factor in thermophilic co-digestion was substrate concentration. But in mesophilic co-digestion, both substrate concentration the mixing ratio had major effects on MPR. The most probable reasons of the synergetic effects in co-digestion of foodwaste and sewage sludge were the balanced nutrient expressed as C/N ratio and increased kinetic constants of hydrolysis by the mixed co-substrates.

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Effect of Partial Replacement of Wheat Flour with High Quality Cassava Flour on the Chemical Composition, Antioxidant Activity, Sensory Quality, and Microbial Quality of Bread

  • Eleazu, Chinedum;Eleazu, Kate;Aniedu, Chinyere;Amajor, John;Ikpeama, Ahamefula;Ebenzer, Ike
    • Preventive Nutrition and Food Science
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    • v.19 no.2
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    • pp.115-123
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    • 2014
  • In the current study, wheat flour was mixed with high quality cassava flour (HQCF) in several ratios: 90:10, 80:20, 70:30, and 60:40, and used to prepare 10%, 20%, 30%, and 40% National Root Crops Research Institute (NRCRI) cassava bread, respectively. 100% wheat bread was prepared as a control (100% wheat bread). Five bread samples were prepared per group. Antioxidant assays [i.e., 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging assay, reducing power assay] revealed that the bread samples had considerable antioxidant capacities. Substitution of wheat flour with HQCF at various concentrations resulted in dose dependent decreases in the mineral and protein contents of the resulting bread samples. The crude fiber content of the bread samples was minimal, while the carbohydrate content of the bread samples ranged from 43.86% to 48.64%. A 20% substitution of wheat flour with HQCF yielded bread samples with a general acceptability that was comparable to that of 100% wheat bread. The mean bacteria counts of the bread samples ranged from $2.0{\times}10^3CFU/mL$ to $1.4{\times}10^4CFU/mL$, while the fungal counts ranged from 0 CFU/mL to $3{\times}10^3CFU/mL$. There was a positive correlation between the DPPH antioxidant activities and the reducing powers of the bread samples ($R^2=0.871$) and a positive correlation between the DPPH antioxidant activities and the flavonoid contents of the bread samples ($R^2=0.487$). The higher microbial load of the NRCRI cassava bread samples indicates that these bread samples may have a shorter shelf life than the 100% wheat bread. The significant positive correlation between total flavonoid content and reducing power ($R^2=0.750$) suggests that the flavonoids present in the lipophilic fractions of the bread samples could be responsible for the reductive capacities of the bread samples.

Study on Image of Future in Modern Fashion (현대 패션의 미래적 이미지에 관한 연구)

  • 김예형;조정미
    • Journal of the Korean Society of Costume
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    • v.53 no.1
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    • pp.35-48
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    • 2003
  • The primary goal of this study is to define the future image of modern fashion. By review of many references, this study has examined predictable future in common, various researches on future, and futurism that appeared from art history. This study has also identified the trend of future image and the properties of the image in terms of fashion as well. The purpose of this study is defined as future image of modern fashion. First of all. through a large literature, this study is to examine general future and the study of future, to investigate futurism appears from art history. and to identify the trend of future image and the properties of the image in terms of fashion. The main results of this study include : 1) General future means forthcoming sometime or a state of life at that time, and future is not drawing near naturally in accordance with the passage of time. The future is developed according as which the owners of time have independent meaning and what they select. 2) The futurism had started with the background based on Darwins and Einsteins scientific theories and Bergsons and Nietzsches philosophical thoughts, which was then established by Marinettis Futurism Statement and Dynamism Theory of Umberto Boccionio, Giaomo Balla, Luigi Russolo and Gino Severini. As the purpose of futurism is to represent the dynamism of machinery and the beauty of speed, it has been developed toward op art and kinetic art including video art, laser art, and holography. 3) Fashion style and trend of futurism from the beginning of 20th century up to now can be defined as follows : Firstly futurism fashion represented by loud colors and geometric pattern appeared from 1910s to 1930s in the first place. Secondly, or art fashion and kinetic fashion appeared in 1960s due to the influence of op art and kinetic art which were developmental arts of futurism paintings. Space Look and Cosmo Corps Look that were designed by Andre Courreges, Pierre Cardin, Rudi Gernreich and Paco Rabanne, were also the trend of future image fashion. Thirdly, various materials and techniques developed this future image fashion in 1980s, and Glitter Look and Collage Look were its representative style. Fourthly, in 1990s, human beings dreamed the freedom of mind by human-oriented thought. and created the ecology of new concept mixed with technology due to anxiety on environmental destruction. which influenced on the advent of Zen style.

Hepatitis C Virus - Proteins, Diagnosis, Treatment and New Approaches for Vaccine Development

  • Keyvani, Hossein;Fazlalipour, Mehdi;Monavari, Seyed Hamid Reza;Mollaie, Hamid Reza
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.5917-5935
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    • 2012
  • Background: Hepatitis C virus (HCV) causes acute and chronic human hepatitis infection and as such is an important global health problem. The virus was discovered in the USA in 1989 and it is now known that three to four million people are infected every year, WHO estimating that 3 percent of the 7 billion people worldwide being chronically infected. Humans are the natural hosts of HCV and this virus can eventually lead to permanent liver damage and carcinoma. HCV is a member of the Flaviviridae family and Hepacivirus genus. The diameter of the virus is about 50-60 nm and the virion contains a single-stranded positive RNA approximately 10,000 nucleotides in length and consisting of one ORF which is encapsulated by an external lipid envelope and icosahedral capsid. HCV is a heterogeneous virus, classified into 6 genotypes and more than 50 subtypes. Because of the genome variability, nucleotide sequences of genotypes differ by approximately 31-34%, and by 20-23% among subtypes. Quasi-species of mixed virus populations provide a survival advantage for the virus to create multiple variant genomes and a high rate of generation of variants to allow rapid selection of mutants for new environmental conditions. Direct contact with infected blood and blood products, sexual relationships and availability of injectable drugs have had remarkable effects on HCV epidemiology. Hundreds of thousands of people die each year from hepatitis and liver cancer caused by HCV virus infection. Approximately 80% of patients with acute hepatitis C progress into a chronic disease state leading to serious hepatic disorders, 10-20% of which develop chronic liver cirrhosis and hepatocellular carcinoma. The incubation period of HCV is 6-8 weeks and the infection is often asymptomatic so it is very hard to detect at early stages, making early treatment very difficult. Therefore, hepatitis C is called a "silent disease". Neutralizing antibodies are produced against several HCV proteins during infection but the virus mutates to escape from antibodies. Some patients with chronic hepatitis C may have some symptoms such as fatigue, muscle aches, nausea and pain. Autoimmune and immunecomplex-mediated diseases have also been reported with chronic HCV infection.