• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.2
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• pp.560-567
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• 2003

Antimetastatic effects of Agaricus mixed prescription (AMP) were studied in the respect of blood-borne metastasis. For this aim, cytotoxicity against various cancer cells and normal cells, Chicken Chorioallantoic membrane (CAM) assay, cancer cell adhesion assay, platelet aggregation assay, pulmonary colonization, life span of S-180 implanted mice, and cytokine release assay were evaluated, respectively. The results were summarized as follows; AMP did not exert any cytotoxicity against all cell lines with IC50 of 25mg/ml on B16BL6. AMP disrupted formation of CAM at 1mg/ml. AMP was suppressive in adhesion assay of B16BL6. AMP also inhibited tumor induced platelet aggregation. In pulmonary colonization assay by B16BL6, the number of colonies in the lungs was significantly decreased in sample group than in control group. In animal study with S-180, the life span of AMP treated group was extended than that of control group. IL-12 was effectively increased in AMP treated group in cytokine release assay. Taken together, AMP can be possibly applied to cancer or metastasis.

• Archives of Plastic Surgery
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• v.33 no.1
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• pp.21-30
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• 2006

Alginate, a polymer of guluronic and mannuronic acid, is used as a scaffolding material in biomedical applications. The research was to produce highly-purified alginate from seaweeds and to evaluate the efficacy of alginate as dermal substrate. Our alginate purification method showed a production rate as high as 25%. The purified alginate contained little polyphenol contents and endotoxin, proteins. For study of wound healing, full thickness skin defects were made on the dorsal area of the animal models. And then alginate, fibroblast-growth-factor mixed alginate, alginate-collagen complex, vaseline gauze as control were applied on the wound, respectively, and were evaluated grossly and histopathologically. For biocompatibility test, alginate and alginate-collagen complex discs were implanted on the back of Sprague-Dawly rats. Four weeks after implantation, the animals were examined immunologically against alginate and collagen. Alginate and FGF-mixed alginate, alginate-collagen complex group showed statistically higher percentage of wound contraction and wound healing than control group(p<0.05). Alginate-collagen complex group and FGF-mixed alginate group showed statistically higher percentage of wound healing than alginate group. The experiment of biocompatibility and immunologic reaction against impanted alginate or collagen needs more investigation. Highly-purified alginate from seaweeds by our purification method, showed the effect of wound healing, and addition of FGF or collagen increases the alginate's wound healing effect. It shows the possibility of alginate as a dermal substrate.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.10a
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• pp.300-303
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• 2015

Digital imaging process has been put to practical use in various application sectors due to a rapid advancement such as memory devices, etc. However, noises are being generated due to various reasons during the image processing and a variety of methods are being studied in order to eliminate these noises. Generally, images are damaged due to a mixed noise having different characteristics. In this paper, a filter algorithm which switches according to the noise types was proposed in order to mitigate the influence of mixed noise included in the image. And using the PSNR as the standard for objective decision making of the improvement effect, it was compared with the existing methods.

• The Korean Journal of Pesticide Science
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• v.18 no.4
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• pp.409-416
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• 2014

This study was conducted to reduce the using amount of chemical fungicides for the control of red-pepper powdery mildew. Effect of combined application of three microbial fungicides and six chemical fungicides for the control of red-pepper powdery mildew was examined in vitro, in pot assay and under field condition. One chemical fungicide (Azoxystrobin+Chlorothalonil) among six chemical fungicides significantly suppressed three microbial fungicides (Bacillus subtilis Y1336, Bacillus subtilis DBB1501, Bacillus subtilis QST-713) registered for the control of pepper powdery mildew in vitro. In the pot assay, two mixed application such as B. subtilis DBB1501+Trifloxystrobin, B. subtilis QST713+Trifloxystrobin among nine mixed applications of three microbial fungicides and three chemical fungicides showed the highest suppressive effect against red pepper powdery mildew. Also, suppressive effect of the mixed application of B. subtilis QST713 and Trifloxystrobin was similar to that of single application of three chemical fungicides(Myclobutanil, Trifloxystrobin, Hexaconazole). In the field test, when the microbial fungicides (B. subtilis DBB1501, B. subtilis QST713) and the chemical fungicide (Trifloxystrobin) for the control of powdery mildew of red pepper were mixed foliar sprayed four times at 7 day-intervals, the control values were in the range of 70.3% to 70.9%. On the other hand, when each of the chemical fungicide (Trifloxystrobin) was foliar sprayed four times at 7 day-intervals, the control value was 72.7%. Consequently, the mixed application of the microbial fungicides and chemical fungicides could be recommended as a one of control measures for reducing the using amount of chemical fungicides.

• 제어로봇시스템학회:학술대회논문집
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• 1994.10a
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• pp.289-292
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• 1994

In this paper, the equations of motion are constructed systematically for multibody systems containing closed kinematic loops. For the displacement analysis of the closed loops, we introduce a new mixed coordinates by adding to the reference coordinates, relative coordinates corresponding to the degrees of freedom of the system. The mixed coordinates makes easy derive the explicit closed form solution. The explicit functional relationship expressed in closed form is of great advantages in system dimension reduction and no need of an iterative scheme for the displacement analysis. This forms of equation are built up in the general purpose computer program for the kinematic and dynamic analysis of multiboty systems.

• Journal of the Korean Ceramic Society
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• v.30 no.6
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• pp.478-484
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• 1993

The influence of reaction conditions on the MnZn ferrite coprecipitation process were investigated using mixed metla sulfate solution and ammonium oxalate. In order to minimize the metallic ion losses and to control the particle size, the optimum reaction conditions were as follows; reaction temperature $25^{\circ}C$, metal sulfate concentration 0.3M, molar ratio of ammonium oxalate/mixed metal sulfate 1.1:1. The production yield was as high as 97.6% of theoretical yield at optimum reaction condition.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.172.5-172
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• 2001

Target Motion Analysis(TMA) for Passive Sonar Systems with bearing-only measurements needs to enhance system observability to improve target tracking performance by ownship maneuvering. However, tracking problem incurred by weak observaility result in slow convergence of the target estimates. On the other hand, active sonar systems do not have problem associated with system observaility. However, it drawback related to system survivability. In this paper, the algorithm that could be used in Active/passive Mixed-Mode Sonar Systems is proposed to analyze maneuvering target motion and to improve TMA performance. The proposed TMA algorithm is tested by a series of computer simulation runs and the results ...

• Magazine of the Korea Concrete Institute
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• v.14 no.4
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• pp.14-21
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• 2002

국내에서 시공되는 콘크리트 구조물의 대부분은 레미콘(ready-mixed concrete)으로 시공되고 있기 때문에 레미콘의 품질관리(quality control) 및 품질확보(quality security)는 곧 콘크리트 구조물의 품질과 내구성의 확보를 위해 매우 중요한 사항이다. 최근 콘크리트 구조물의 잦은 사고로 인해 콘크리트의 품질문제가 사회문제로 나타나고 있으며 이에 대비한 콘크리트 품질보증 시스템의 확립이 시급한 실정이다. 그러나 레미콘의 품질환경은 원재료의 품질저하, 레미콘 운반시간의 증대 및 기술개발의 미흡 등 주변여건이 좋은 편은 아니며 레미콘 산업도 경쟁시대에 돌입하면서 레미콘 품질이나 기술우위의 시대로 변화되고 있다.(중략)

• 유체기계공업학회:학술대회논문집
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• 2003.12a
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• pp.464-468
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• 2003

A general program of three dimensional profile design of impellers for centrifugal/fixed-flow compressors is successfully commercialized using Bezier curves and quasi-3D flow analysis methods. Control points for meridional hub and shroud contours and blade camberline angles are arbitrarily changed to give smooth Bezier curves. With specified blade normal thicknesses, contructed geometry is instantly analyzed using flow analysis methods to be checked.

• KIEE International Transaction on Systems and Control
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• v.12D no.1
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• pp.39-42
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• 2002

This paper focuses on the asymptotic stability of a class of neutral linear systems with mixed time-varying delay arguments. Using the Lyapunov method, a delay-dependent stability criterion to guarantee the asymptotic stability for the systems is derived in terms of linear matrix inequalities (LMIs). The LMIs can be easily solved by various convex optimization algorithms. Two numerical examples are given to illustrate the proposed methods.