• 제목/요약/키워드: miscarriage

검색결과 121건 처리시간 0.023초

자궁 내 기저질환을 가진 고령의 반복 유산 환자 2례에 관한 고찰 (Two Cases Report of Recurrent Miscarriage with Old Age and Underlying Diseases)

  • 김수현;김동일
    • 대한한방부인과학회지
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    • 제29권3호
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    • pp.78-90
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    • 2016
  • Objectives: The purpose of these cases is to report the effects of Korean medicine on two women with recurrent miscarriage.Methods: One women who had recurrent miscarriage with myoma uteri was 39 years old. She was treated with herbal medicine and acupuncture until intrauterine pregnancy (IUP) 14 wks. the other who had recurrent miscarriage with adenomyosis was 40 years old. she was also treated with these until IUP 11 wks.Results: After treatment, one women delivered successfully by normal full term spontaneous delivery. The other succeeded in normal pregnancy and she is 15 weeks pregnant.Conclusions: Two cases show that Korean Medicine has effects on recurrent miscarriage with old age and underlying diseases.

Impact of sperm DNA fragmentation on clinical in vitro fertilization outcomes

  • Choi, Hwa Young;Kim, Seul Ki;Kim, Seok Hyun;Choi, Young Min;Jee, Byung Chul
    • Clinical and Experimental Reproductive Medicine
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    • 제44권4호
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    • pp.224-231
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    • 2017
  • Objective: We studied the association between sperm DNA fragmentation (SDF) and several clinical in vitro fertilization outcomes. Methods: We retrospectively analyzed 169 consecutive fresh IVF cycles. Semen was collected on the day of oocyte retrieval, and we assessed standard semen parameters and the SDF level (by terminal deoxynucleotidyl transferase dUTP nick-end labeling). Poor ovarian response (POR) was defined as the collection of three or fewer mature oocytes. Oocytes were inseminated by the conventional method or intracytoplasmic sperm injection. Results: SDF did not affect the fertilization or pregnancy rate, but did have a significant effect on the miscarriage rate. In the miscarriage group (n = 10), the SDF level was significantly higher (23.9% vs. 14.1%) and number of mature oocytes was significantly lower (4.3 vs. 7.6) than in the live birth group (n = 45). Multiple regression analysis showed that SDF was an independent predictor of miscarriage (odds ratio, 1.051; 95% confidence interval, 1.001-1.104). The cutoffs for the SDF level and number of mature oocytes that could predict miscarriage were > 13% and ${\leq}3$, respectively. In the low-SDF group (${\leq}13%$), the miscarriage rate was similar in POR patients and those with a normal ovarian response (NOR; 14.2% vs. 4.3%). In the high-SDF group ( > 13%), the miscarriage rate was significantly higher in the POR group than in the NOR group (60.0% vs. 13.3%, p= 0.045). Conclusion: Our study demonstrated that a high SDF level ( > 13%) was associated with a high miscarriage rate, and that it mainly contributed to miscarriage in the POR group. The results suggest that SDF measurements should be considered in couples with POR in order to predict the prognosis of the pregnancy.

동의보감(東醫寶鑑)에 활용된 사인(砂仁)의 안태기능(安胎機能) 연구 (The study on preventive effects of Fructus Amomi on miscarriage in Dongeui-bogam)

  • 김형우;신우철;심승용;심창민;여선미;조수인
    • 대한본초학회지
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    • 제22권4호
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    • pp.247-252
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    • 2007
  • Objectives : Fructus Amomi has been widely used to treat patients with anorexia and dyspepsia induced by moisture or cold. In addition, it is known to have preventive effects on miscarriage. But, this preventive effect of Fructus Amomi has controversial point. For this reason, this study was designed to investigate the preventive effects of Fructus Amomi on miscarriage in the framework of usage. Methods : We investigated the preventive effects of Fructus Amomi on miscarriage in terms of checking frequency in use of Fructus Amomi in Dongeui-bogam. Results : Fructus Amomi was used by 192 times in Dongeuh-bogam. it was used by 36 times in major drug, the others used in complementary drug. 14 remedies were used to treat patients with gynecologic diseases. In these remedies, 7 remedies were related to preventive effects of Fructus Amomi on miscarriage. In thses 7 remedies, 6 were used with samul-tang or Radix Scutellariae and Rizoma Atractylodis Macrocephalae. Conclusions : These results suggest the possibility that preventive effects of Fructus Amomi on miscarriage is not involved in direct efficacy, which was explained with gimi-ron, but in usage of the herbal medicine.

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