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The Evaluation of Non-Coplanar Volumetric Modulated Arc Therapy for Brain stereotactic radiosurgery (뇌 정위적 방사선수술 시 Non-Coplanar Volumetric Modulated Arc Therapy의 유용성 평가)

  • Lee, Doo Sang;Kang, Hyo Seok;Choi, Byoung Joon;Park, Sang Jun;Jung, Da Ee;Lee, Geon Ho;Ahn, Min Woo;Jeon, Myeong Soo
    • The Journal of Korean Society for Radiation Therapy
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    • v.30 no.1_2
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    • pp.9-16
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    • 2018
  • Purpose : Brain Stereotactic Radiosurgery can treat non-invasive diseases with high rates of complications due to surgical operations. However, brain stereotactic radiosurgery may be accompanied by radiation induced side effects such as fractionation radiation therapy because it uses radiation. The effects of Coplanar Volumetric Modulated Arc Therapy(C-VMAT) and Non-Coplanar Volumetric Modulated Arc Therapy(NC-VMAT) on surrounding normal tissues were analyzed in order to reduce the side effects caused fractionation radiation therapy such as head and neck. But, brain stereotactic radiosurgery these contents were not analyzed. In this study, we evaluated the usefulness of NC-VMAT by comparing and analyzing C-VMAT and NC-VMAT in patients who underwent brain stereotactic radiosurgery. Methods and materials : With C-VMAT and NC-VMAT, 13 treatment plans for brain stereotactic radiosurgery were established. The Planning Target Volume ranged from a minimum of 0.78 cc to a maximum of 12.26 cc, Prescription doses were prescribed between 15 and 24 Gy. Treatment machine was TrueBeam STx (Varian Medical Systems, USA). The energy used in the treatment plan was 6 MV Flattening Filter Free (6FFF) X-ray. The C-VMAT treatment plan used a half 2 arc or full 2 arc treatment plan, and the NC-VMAT treatment plan used 3 to 7 Arc 40 to 190 degrees. The angle of the couch was planned to be 3-7 angles. Results : The mean value of the maximum dose was $105.1{\pm}1.37%$ in C-VMAT and $105.8{\pm}1.71%$ in NC-VMAT. Conformity index of C-VMAT was $1.08{\pm}0.08$ and homogeneity index was $1.03{\pm}0.01$. Conformity index of NC-VMAT was $1.17{\pm}0.1$ and homogeneity index was $1.04{\pm}0.01$. $V_2$, $V_8$, $V_{12}$, $V_{18}$, $V_{24}$ of the brain were $176{\pm}149.36cc$, $31.50{\pm}25.03cc$, $16.53{\pm}12.63cc$, $8.60{\pm}6.87cc$ and $4.03{\pm}3.43cc$ in the C-VMAT and $135.55{\pm}115.93cc$, $24.34{\pm}17.68cc$, $14.74{\pm}10.97cc$, $8.55{\pm}6.79cc$, $4.23{\pm}3.48cc$. Conclusions : The maximum dose, conformity index, and homogeneity index showed no significant difference between C-VMAT and NC-VMAT. $V_2$ to $V_{18}$ of the brain showed a difference of at least 0.5 % to 48 %. $V_{19}$ to $V_{24}$ of the brain showed a difference of at least 0.4 % to 4.8 %. When we compare the mean value of $V_{12}$ that Radione-crosis begins to generate, NC-VMAT has about 12.2 % less amount than C-VMAT. These results suggest that if NC-VMAT is used, the volume of $V_2$ to $V_{18}$ can be reduced, which can reduce Radionecrosis.

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Seasonal and Yearly Variations of Atmospheric Extinction Coefficient at Campus Station of Chungbuk National University Observatory from 2005 to 2007 (충북대학교 천문대 교내관측소에서 측정된 2005년부터 2007년까지의 대기소광계수의 계절별, 년도별 변화)

  • Kim, Chun-Hwey;Cha, Sang-Mok;Choi, Young-Jae;Song, Mi-Hwa;Park, Jang-Ho;Won, Jang-Hee;Yim, Jin-Sun;Cho, Myung-Shin;Park, Eun-Mi;Jeong, Jang-Hae
    • Journal of Astronomy and Space Sciences
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    • v.25 no.2
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    • pp.101-112
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    • 2008
  • Systematic CCD observations of times of minimum lights for eclipsing binaries has been carried out from 2002 to 2007 at Campus Station of Chungbuk National University Observatory which is located in Cheongju city, Korea. As a by-product of our observations, photometric data for stars in CCD images taken from 2005 to 2007 were used to determine 1st order atmospheric extinction coefficient (hereafter AEC) and seasonal and yearly variations of the AECs were studied. Total nights used for determination of AECs were 57 days in 2005, 51 days in 2006, and 63 days in 2007. As a result the annual mean value of the AECs per air mass is calculated as $0.^m34{\pm}0.^m18$ for 2005, $0.^m38{\pm}0.^m19$ for 2006, and $0.^m45{\pm}0.^m20$ for 2007. These values show that the AECs and their standard deviations are two and four times, respectively, larger than those of normal observatories which are not located near large cities. Annual comparison between concentration of atmospheric fine dust and coefficient of atmospheric extinction show strong correlation between two quantities of which time variations show similar patterns. The AECs for the east sky show larger than those for the west sky. It can be easily understood by the reasonable possibility that air pollutants remain more in the east sky than in the west because the east area of Cheongju city has been more developed than the west one. In conclusion the atmospheric extinction of the night sky of Cheongju city has an annual trend of increase of $0.^m06\;airrnass^{-1}\; year^{-1}$ implying that it may take only about 13 years for Cheongju city to have 2 times brighter night sky than the present one. Our study highlights that variations of AEC can be used as an important indicator of air pollution to monitor night skies.

Evaluation of dose delivery accuracy due to variation in pitch and roll (세기변조방사선치료에서 Pitch와 Roll 변화에 따른 선량전달 정확성 평가)

  • Jeong, Chang Young;Bae, Sun Myung;Lee, Dong Hyung;Min, Soon Ki;Kang, Tae Young;Baek, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.239-245
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    • 2014
  • Purpose : The purpose of this study is to verify the accuracy of dose delivery according to the pitch and roll rotational setup error with 6D robotic couch in Intensity Modulated Radiation Therapy (IMRT) for pelvic region in patients. Materials and Methods : Trilogy(Varian, USA) and 6D robotic couch(ProturaTM 1.4, CIVCO, USA) were used to measure and analyze the rotational setup error of 14 patients (157 setup cases) for pelvic region. The total 157 Images(CBCT 78, Radiography 79) were used to calculate the mean value and the incidence of pitch and roll rotational setup error with Microsoft Office Excel 2007. The measured data (3 mm, 3%) at the reference angle ($0^{\circ}$) without couch rotation of pitch and roll direction was compared to the others at different pitch and roll angles ($1^{\circ}$, $1.5^{\circ}$, $2^{\circ}$, $2.5^{\circ}$) to verify the accuracy of dose delivery by using 2D array ionization chamber (I'mRT Matrixx, IBA Dosimetry, Germany) and MultiCube Phantom(IBA Dosimetry, Germany). Result from the data, gamma index was evaluated. Results : The mean values of pitch and roll rotational setup error were $0.9^{\circ}{\pm}0.7$, $0.5^{\circ}{\pm}0.6$. The maximum values of them were $2.8^{\circ}$, $2.0^{\circ}$. All of the minimum values were zero. The mean values of gamma pass rate at four different pitch angles ($1^{\circ}$, $1.5^{\circ}$, $2^{\circ}$, $2.5^{\circ}$) were 97.75%, 96.65%, 94.38% and 90.91%. The mean values of gamma pass rate at four different roll angles ($1^{\circ}$, $1.5^{\circ}$, $2^{\circ}$, $2.5^{\circ}$) were 93.68%, 93.05%, 87.77% and 84.96%. when the same angles ($1^{\circ}$, $1.5^{\circ}$, $2^{\circ}$) of pitch and roll were applied simultaneously, The mean values of each angle were 94.90%, 92.37% and 87.88%, respectively. Conclusion : As a result of this study, it was able to recognize that the accuracy of dose delivered is lowered gradually as pitch and roll increases. In order to increase the accuracy of delivered dose, therefore, it is recommended to perform IGRT or correct patient's position in the pitch and roll direction, to improve the quality of treatment.

Evaluation on Usefulness of Stereotactic Radio Surgery using $Fraxion^{(R)}$ System ($Fraxion^{(R)}$ System을 이용한 뇌 정위적 방사선 수술 유용성 평가)

  • Kim, Tae Won;Park, Kwang Woo;Ha, Jin Sook;Jeon, Mi Jin;Cho, Yoon Jin;Kim, Sei Joon;Kim, Jong Dae;Shin, Dong Bong
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.345-354
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    • 2014
  • Purpose : We evaluated the usefulness of $Fraxion^{(R)}$ system and s-thermoplastic mask by analyzing setup error when stereotactic radiousurgery (SRS) was treated for brain metastasis. Materials and Methods : 6 patients who received definite diagnosis as brain metastasis between May 2014 and October 2014 were selected. 3 patients were immobilized s-thermoplastic mask and mouthpiece (group1), while $Fraxion^{(R)}$ system was used for the other 3 patients (group2). Cone Beam Computerized Tomography (CBCT) scan was acquired to register planning CT scan. The registration offset was compared for each group. We compared and reported the errors using maximum, minimum, mean, and standard deviation of registration offsets. Furthermore, We used the same method as patient specific quality assurance to verify absorbed dose of PTV. Results : The setup error which is registration offset was reduced 83% in x, 40% in y, and 92% in z-direction when $Fraxion^{(R)}$ system was used compared to the case of using s-thermoplastic mask and mouthpiece. In addition, using $Fraxion^{(R)}$ system showed improved results in rotational components, pitch (rotation along x-axis), roll (y), and yaw (z) which were reduced 64, 88, and 87% respectively compared to the case of using s-thermoplastic mask and mouthpiece. In dosimetry results, when s-thermoplastic mask and mouthpiece used, absorbed dose was reduce 83% compared to before and after registration. However, using $Fraxion^{(R)}$ system showed only 1.9%. All percentage were calculated with respect to average value. Conclusion : Using $Fraxion^{(R)}$ system including mouthpiece, Fraxion frame, frontpiece, and thermoplastic mask, showed better repeatability and precision compared to using s-thermoplastic mask and mouthpiece, which is consequently considered as more improved immobilization system.

Marine Algal Flora and Community Structure of Gogunsan Islands outside the Saemangeum Dike (새만금 방조제 외측 고군산군도 지역의 해조상 및 군집구조)

  • Kim, Ju-Hee;Ko, Yong-Deok;Kim, Young-Sik;Nam, Ki-Wan
    • Korean Journal of Environment and Ecology
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    • v.25 no.2
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    • pp.156-165
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    • 2011
  • It is selected seven sites for marine algal flora and community structure and investigated seasonally from December 2008 to November 2009 in Gogunsan Islands, the west coast of Korea. A total of 58 species including 10 green, 16 brown and 32 red algae were collected and identified. Among these species, 11 species were found throughout the year. Annual mean biomass in dry weight were 213.8 g $m^{-2}$ at Sinsido 1, 143.1 g $m^{-2}$ at Sinsido 2, 133.3 g $m^{-2}$ at Sinsido 3, 164.0 g $m^{-2}$ at Munyeodo, 116.9 g $m^{-2}$ at Seonyudo, and 145.1 g $m^{-2}$ at Jangjado. Maximum biomass was recorded in Sinsido 1, and minimum mean biomass was Sinsido 4. The dominant species based on biomass were Sargassum thunbergii, Ulva pertusa, Sargassum fusiforme and Corallina pilulifera. S. thunbergii was the representative alga occurred at all seasons. The flora investigated could be classified into six functional groups such as coarsely branched form (46.6%), filamentous form (27.6%), sheet form (17.2%), thick leathery form (3.4%), jointed calcareous form (3.4%) and crustose form (1.7%). The R/P, C/P and (R+C)/P value reflecting flora characteristics were 0.33~0.75, 1.11~2.50, 1.47~3.25, respectively. Diversity index (H') and dominance index (DI) indicated that stability of seaweed community of Gogunsan Islands was unstable and environmental conditions were bad. According to multidimensional scaling (MDS) and cluster analysis, Gogunsan Islands were divided into three distinct groups. The first group was Sinsido 2, Sinsido 3, Seonyudo and Muyeodo and the second group comprised Sinsido 1 and Jangjado and the other was Sinsido 4 due to meaningful difference in similarity.

Revision of an iodine database for Korean foods and evaluation of dietary iodine and urinary iodine in Korean adults using 2013-2015 Korea National Health and Nutrition Examination Survey (한국인 상용 식품의 요오드 데이터베이스 업데이트와 이를 활용한 한국 성인의 요오드 섭취량 및 배설량 평가: 2013-2015 국민건강영양조사자료를 이용하여)

  • Choi, Ji Yeon;Ju, Dal Lae;Song, YoonJu
    • Journal of Nutrition and Health
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    • v.53 no.3
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    • pp.271-287
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    • 2020
  • Purpose: Variations in the iodine contents of foods is critical for estimating the iodine intake. This study aimed to update the iodine database of common Korean foods and evaluated the iodine intake in Korean adults. Methods: A list of 855 Korean foods was selected for the updated iodine database. The updated database was established with Version 1 and 2 by applying an average or minimum value for the imputed values. The iodine intake was estimated in 5,927 Korean adults using the data from the 2013-2015 Korea National Health and Nutrition Examination Survey. Results: The analytical values in the updated database were 166 (19.4%), followed in order by 318 (37.2%), 247 (28.9%), and 124 (14.5%) for the adapted, imputed, and missing values, respectively. The median of dietary iodine intake was 352.1 ㎍/day (± 2,166.1) and 343.4 ㎍/day (± 2,161.9) in Version 1 and 2 among the total population. The contribution rates of each food group to the iodine intake were 55.7% for seaweeds, which showed a similar trend in Version 2. When subjects were divided by consumption of seaweeds, the median iodine intake was 495.7 ㎍ in the consumer group, which was almost double (241.2 ㎍) that of the non-consumer group. The proportion of subjects who consumed below the Estimated Average Requirement of iodine was 11.0% in the non-consumer group. In contrast, 11.6% in the consumer group of seaweed consumed above the Upper Level of iodine. When the dietary iodine and urinary iodine were examined, the regression coefficient was 0.11718 in Version 1 and 0.11512 in Version 2 after adjusting for age and sex. Conclusion: This study presented the variation of iodine intake in Korean adults by applying different versions of the iodine database. As the iodine intake can vary due to the highly variable concentrations in the major food sources, an iodine database is necessary to be monitored, and caution should be taken when the database is used in research.

Calculation of Surface Broadband Emissivity by Multiple Linear Regression Model (다중선형회귀모형에 의한 지표면 광대역 방출율 산출)

  • Jo, Eun-Su;Lee, Kyu-Tae;Jung, Hyun-Seok;Kim, Bu-Yo;Zo, Il-Sung
    • Journal of the Korean earth science society
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    • v.38 no.4
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    • pp.269-282
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    • 2017
  • In this study, the surface broadband emissivity ($3.0-14.0{\mu}m$) was calculated using the multiple linear regression model with narrow bands (channels 29, 30, and 31) emissivity data of the Moderate Resolution Imaging Spectroradiometer (MODIS) on Earth Observing System Terra satellite. The 307 types of spectral emissivity data (123 soil types, 32 vegetation types, 19 types of water bodies, 43 manmade materials, and 90 rock) with MODIS University of California Santa Barbara emissivity library and Advanced Spaceborne Thermal Emission & Reflection Radiometer spectral library were used as the spectral emissivity data for the derivation and verification of the multiple linear regression model. The derived determination coefficient ($R^2$) of multiple linear regression model had a high value of 0.95 (p<0.001) and the root mean square error between these model calculated and theoretical broadband emissivities was 0.0070. The surface broadband emissivity from our multiple linear regression model was comparable with that by Wang et al. (2005). The root mean square error between surface broadband emissivities calculated by models in this study and by Wang et al. (2005) during January was 0.0054 in Asia, Africa, and Oceania regions. The minimum and maximum differences of surface broadband emissivities between two model results were 0.0027 and 0.0067 respectively. The similar statistical results were also derived for August. The surface broadband emissivities by our multiple linear regression model could thus be acceptable. However, the various regression models according to different land covers need be applied for the more accurate calculation of the surface broadband emissivities.

Classification of the Core Climatic Region Established by the Entropy of Climate Elements - Focused on the Middle Part Region - (기후요소의 엔트로피에 의한 핵심 기후지역의 구분 - 중부지방을 중심으로 -)

  • Park, Hyun-Wook;Chung, Sung-Suk;Park, Keon-Yeong
    • Journal of the Korean earth science society
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    • v.27 no.2
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    • pp.159-176
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    • 2006
  • Geographic factors and mathmatical location of the Korean Peninsula have great influences on the variation patterns and appearances over a period of ten days of summer precipitation. In order to clarify the influence of several climate factors on precise climate classification in the middle part region of the Korea, weather entropy and the information ratio were calculated on the basis of information theory and of the data of 25 site observations. The data used for this study are the daily precipitation phenomenon over a period of ten days of summer during the recent thirteen years (1991-2003) at the 25 stations in the middle part region of the Korea. It is divided into four classes of no rain, $0.1{\sim}10.0mm/day,\;10.1{\sim}30.0mm/day$, 30.1mm over/day. Their temporal and spatial change were also analyzed. The results are as follows: the maximum and minimum value of calculated weather entropy are 1.870 bits at Chuncheon in the latter ten days of July and 0.960 bits at Ganghwa during mid September, respectively. And weather entropy in each observation sites tends to be larger in the beginning of August and smaller towards the end of September. The largest and smallest values of weather representative ness based on information ratio were observed at Chungju in the beginning of June and at Deagwallyeong towards the end of July. However, the largest values of weather representativeness came out during the middle or later part of September when 15 sites were adopted as the center of weather forecasting. The representative core region of weather forecasting and climate classification in the middle part region of the Korea are inside of the triangle region of the Buyeo, Incheon, and Gangneung.

Validation of Sea Surface Wind Speeds from Satellite Altimeters and Relation to Sea State Bias - Focus on Wind Measurements at Ieodo, Marado, Oeyeondo Stations (인공위성 고도계 해상풍 검증과 해상상태편차와의 관련성 - 이어도, 마라도, 외연도 해상풍 관측치를 중심으로 -)

  • Choi, Do-Young;Woo, Hye-Jin;Park, Kyung-Ae;Byun, Do-Seong;Lee, Eunil
    • Journal of the Korean earth science society
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    • v.39 no.2
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    • pp.139-153
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    • 2018
  • The sea surface wind field has long been obtained from satellite scatterometers or passive microwave radiometers. However, the importance of satellite altimeter-derived wind speed has seldom been addressed because of the outstanding capability of the scatterometers. Satellite altimeter requires the accurate wind speed data, measured simultaneously with sea surface height observations, to enhance the accuracy of sea surface height through the correction of sea state bias. This study validates the wind speeds from the satellite altimeters (GFO, Jason-1, Envisat, Jason-2, Cryosat-2, SARAL) and analyzes characteristics of errors. In total, 1504 matchup points were produced using the wind speed data of Ieodo Ocean Research Station (IORS) and of Korea Meteorological Administration (KMA) buoys at Marado and Oeyeondo stations for 10 years from December 2007 to May 2016. The altimeter wind speed showed a root mean square error (RMSE) of about $1.59m\;s^{-1}$ and a negative bias of $-0.35m\;s^{-1}$ with respect to the in-situ wind speed. Altimeter wind speeds showed characteristic biases that they were higher (lower) than in-situ wind speeds at low (high) wind speed ranges. Some tendency was found that the difference between the maximum and minimum value gradually increased with distance from the buoy stations. For the improvement of the accuracy of altimeter wind speed, an equation for correction was derived based on the characteristics of errors. In addition, the significance of altimeter wind speed on the estimation of sea surface height was addressed by presenting the effect of the corrected wind speeds on the sea state bias values of Jason-1.

A Study on the Intenna Based on PIFA with Multi Element (Mulit Element를 이용한 PIFA 구조의 Intenna에 관한 연구)

  • Lim, Yo-Han;Chang, Ki-Hun;Yoon, Young-Joong;Kim, Yong-Jin;Kim, Young-Eil;Yoon, Ick-Jae
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.18 no.7
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    • pp.784-795
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    • 2007
  • In this thesis, the Multi element antenna with wideband and enhanced gain characteristic is proposed to operate at both frequency range from 824 MHz to 896 11Hz for the CDMA and frequency range from 908.5 MHz to 914 MHz for the RFID band. The proposed antenna has tile size of $35{\times}15{\times}5mm^3$ in order to put it in the A model of S company and each element of the proposed antenna is folded to obtain the minimum size. To obtain the antenna with wideband and high gain characteristic, the radiator of the antenna is divided into 4 elements. As a result, bandwidth of the proposed antenna become broader and lower center frequency is appeared due to increased and lengthened current path. Moreover, the enhanced gain characteristic is verified because divided element structure that induct uniform current distribution can get increased antenna efficiency. To attain more uniform current distribution, modified structure of the feeding point that can deliver currents directly is designed. The antenna that alters the feeding structure has higher gain value. Each element is folded to increase the current paths considering the current directions to attain the miniaturization of the antenna. To measure the handset antenna, the handset case must be considered. Even though antenna is designed for predicted characteristic, the resonance frequency is shifted and antenna gain is deteriorated at predicted frequency while antenna is set in the handset case. 1.08 GHz of the resonant frequency is determined after frequency shift from 150 MHz to 200 MHz is confirmed and the maximum gain is measured as 3.1 dBi while antenna is not set in the handset. In case handset case is considered, the experimental results show that the impedance bandwidth for VSWR<2 is from 0.824 GHz to 0.936 GHz(110 MHz). This result appears that the proposed antenna can cover both CDMA and RFID band at once. The measured gain is from -3.4 dBi to -0.5 dBi and it has omni-directional pattern practically.