• 제목/요약/키워드: minimum risk

검색결과 436건 처리시간 0.028초

해수 및 수산물에서 분리한 Vibrio vulnificus의 병원성 유전자 및 항균제 내성 (Profiles of Virulence Genes and Antimicrobial Resistance of Vibrio vulnificus Strains Isolated from Seawater and Fisheries)

  • 박권삼;조의동;김희대
    • 한국수산과학회지
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    • 제54권6호
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    • pp.918-926
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    • 2021
  • We isolated 28 Vibrio vulnificus strains from seawater and fisheries and investigated the positive rate of eight virulence genes. Additionally, we evaluated the susceptibility of these strains to 25 antimicrobials. The positive rates of fur, vvhA, tcp, rtxA, vcgC, viuB, vvp, and acfA were 100, 92.9, 92.9, 67.9, 64.3, 25.0, 14.3, and 7.1%, respectively. A disk diffusion susceptibility test revealed that, all the investigated strains had the highest resistance to amoxicillin and oxacillin, followed by that to streptomycin (96.4%), cefoxitin (92.9%), clindamycin (82.1%), amikacin (67.9%), vancomycin (46.4%), nalidixic acid (7.1%), penicillin G (7.1%), and ampicillin (3.6%). Moreover, they were susceptible to 10 other antimicrobials, including cefotaxime, chloramphenicol, erythromycin, gentamicin, and rifampicin. Notably, amoxicillin, oxacillin, and streptomycin had average minimum inhibitory concentrations of 132.6, 603.4, and 23.1 ㎍/mL against V. vulnificus, respectively. These observations provide new insights regarding the necessity for sanitation of commercial fisheries and can potentially, help reduce the risk posed by fisheries contaminated with bacteria resistant to antimicrobials.

금강 하구 해역의 해수에서 분리한 장염비브리오(Vibrio parahaemolyticus) 균의 특성 및 항균제 내성 (Characterization and Antimicrobial Resistance of Vibrio parahaemolyticus Strains Isolated from Seawater of Geum River Estuary Area, West Coast of Korea)

  • 이신혜;김희대;박권삼
    • 한국수산과학회지
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    • 제55권6호
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    • pp.850-857
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    • 2022
  • Seventy-five Vibrio parahaemolyticus isolates from the surface seawater of the Geum River Estuary area, on the west coast of Korea, were analyzed for the presence of virulence genes and susceptibility to 17 different antimicrobials. All 75 isolates were examined for the presence of two virulence genes (tdh or trh) using polymerase chain reaction; Only one of the isolates possessed the tdh or trh gene. According to the results of disk diffusion susceptibility tests, all of the strains were resistant to penicillin G, 92.0% were resistant to ampicillin, 82.7% were resistant to amoxicillin, 2.7% were resistant to ciprofloxacin, 2.7% were resistant to trimethoprim, 1.3% were resistant to cephalothin, and 1.3% were resistant to erythromycin. However, all of the strains were susceptible to amikacin, cefoxitin, chloramphenicol, gentamycin, kanamycin, nalidixic acid, nitrofurantoin, rifampin, streptomycin, and tetracycline. The average minimum inhibitory concentrations for ampicillin for V. parahaemolyticus was 557.6 ㎍/mL. These results not only provide novel insight into the necessity for seawater sanitation in Geum river estuary area, but they help reduce the risk of contamination of antimicrobial-resistant bacteria.

Indoor air quality evaluation in intercity buses in real time traffic

  • Kazim O. Demirarslan;Serden, Basak
    • Advances in environmental research
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    • 제11권1호
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    • pp.17-30
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    • 2022
  • Road transport allows all forms of land conditions to be met at less cost. Because of this function, despite numerous disadvantages, it becomes the most frequently used method of transport, especially in underdeveloped or developing countries. One of the most significant factors used in evaluating the atmosphere's air quality is the amount of CO2, increasing people's density in indoor spaces. The amount of CO2 indoors is, therefore, vital to determine. In this study, CO2 and temperature measurements made on nine different bus journey was made in Turkey. The minimum and maximum values were recorded as 555 ppm and 3000 ppm CO2, respectively, in the measurements. On all journeys, the average concentration is 1088.72 ppm. The minimum and maximum values were measured as 17.4℃ and 32.7℃ in the temperature measurements, and the average of all trips was calculated to be 25.76℃. In this study conducted before the Covid-19 pandemic, it was determined that the amount of CO2 increased with the density and insufficient ventilation in the buses. The risk of infection increases in places with high human density and low clean air. For situations such as pandemics, CO2 measurement is a rapid indicator of determining human density.

시판 젓갈에서 분리한 Clostridium perfringens의 독소 유전자 및 항균제 내성 분석 (Toxin Genes and Antimicrobial Resistance of Clostridium perfringens Strains Isolated from Commercial Jeotgals)

  • 이신혜;박권삼
    • 한국수산과학회지
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    • 제56권6호
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    • pp.826-832
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    • 2023
  • Clostridium perfringens causes diarrhea and other diseases in humans and animals. We investigated the prevalence, toxin gene profiles, and antimicrobial resistance of C. perfringens isolated from commercial jeotgal sample. C. perfringens was isolated from 11 of 22 commercial jeotgals. All C. perfringens strains were positive for the alpha toxin gene, but not for the beta, epsilon, iota, CPE or NetB toxin genes; therefore, all strains were identified as type A C. perfringens. However, the beta2 toxin gene was identified in 54.5% of isolates. Disk diffusion susceptibility tests showed that most isolates were resistant to kanamycin (90.9%), nalidixic acid (72.7%), oxacillin (54.5%), erythromycin (27.3%), ciprofloxacin (9.1%) and clindamycin (9.1%). However, all strains were susceptible to 14 other antimicrobial including amoxicillin, ampicillin, and chloramphenicol. The average minimum inhibitory concentrations against C. perfringens of clindamycin, kanamycin, and nalidixic acid were 128.0, 128.0, and 54.0 ㎍/mL, respectively. These results provide new insight into the necessity for sanitation of commercial jeotgal, and provide evidence to help reduce the risk of contamination with antimicrobial-resistant bacteria.

인지된 위험의 유형이 소비자 신뢰 및 온라인 구매의도에 미치는 영향 (The Impact of Perceived Risks Upon Consumer Trust and Purchase Intentions)

  • 홍일유;김우성;임병하
    • Asia pacific journal of information systems
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    • 제21권4호
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    • pp.1-25
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    • 2011
  • Internet-based commerce has undergone an explosive growth over the past decade as consumers today find it more economical as well as more convenient to shop online. Nevertheless, the shift in the common mode of shopping from offline to online commerce has caused consumers to have worries over such issues as private information leakage, online fraud, discrepancy in product quality and grade, unsuccessful delivery, and so forth, Numerous studies have been undertaken to examine the role of perceived risk as a chief barrier to online purchases and to understand the theoretical relationships among perceived risk, trust and purchase intentions, However, most studies focus on empirically investigating the effects of trust on perceived risk, with little attention devoted to the effects of perceived risk on trust, While the influence trust has on perceived risk is worth studying, the influence in the opposite direction is equally important, enabling insights into the potential of perceived risk as a prohibitor of trust, According to Pavlou (2003), the primary source of the perceived risk is either the technological uncertainty of the Internet environment or the behavioral uncertainty of the transaction partner. Due to such types of uncertainty, an increase in the worries over the perceived risk may negatively affect trust, For example, if a consumer who sends sensitive transaction data over Internet is concerned that his or her private information may leak out because of the lack of security, trust may decrease (Olivero and Lunt, 2004), By the same token, if the consumer feels that the online merchant has the potential to profit by behaving in an opportunistic manner taking advantage of the remote, impersonal nature of online commerce, then it is unlikely that the merchant will be trusted, That is, the more the probable danger is likely to occur, the less trust and the greater need to control the transaction (Olivero and Lunt, 2004), In summary, a review of the related studies indicates that while some researchers looked at the influence of overall perceived risk on trust level, not much attention has been given to the effects of different types of perceived risk, In this context the present research aims at addressing the need to study how trust is affected by different types of perceived risk, We classified perceived risk into six different types based on the literature, and empirically analyzed the impact of each type of perceived risk upon consumer trust in an online merchant and further its impact upon purchase intentions. To meet our research objectives, we developed a conceptual model depicting the nomological structure of the relationships among our research variables, and also formulated a total of seven hypotheses. The model and hypotheses were tested using an empirical analysis based on a questionnaire survey of 206 college students. The reliability was evaluated via Cronbach's alphas, the minimum of which was found to be 0.73, and therefore the questionnaire items are all deemed reliable. In addition, the results of confirmatory factor analysis (CFA) designed to check the validity of the measurement model indicate that the convergent, discriminate, and nomological validities of the model are all acceptable. The structural equation modeling analysis to test the hypotheses yielded the following results. Of the first six hypotheses (H1-1 through H1-6) designed to examine the relationships between each risk type and trust, three hypotheses including H1-1 (performance risk ${\rightarrow}$ trust), H1-2 (psychological risk ${\rightarrow}$ trust) and H1-5 (online payment risk ${\rightarrow}$ trust) were supported with path coefficients of -0.30, -0.27 and -0.16 respectively. Finally, H2 (trust ${\rightarrow}$ purchase intentions) was supported with relatively high path coefficients of 0.73. Results of the empirical study offer the following findings and implications. First. it was found that it was performance risk, psychological risk and online payment risk that have a statistically significant influence upon consumer trust in an online merchant. It implies that a consumer may find an online merchant untrustworthy if either the product quality or the product grade does not match his or her expectations. For that reason, online merchants including digital storefronts and e-marketplaces are suggested to pursue a strategy focusing on identifying the target customers and offering products that they feel best meet performance and psychological needs of those customers. Thus, they should do their best to make it widely known that their products are of as good quality and grade as those purchased from offline department stores. In addition, it may be inferred that today's online consumers remain concerned about the security of the online commerce environment due to the repeated occurrences of hacking or private information leakage. Online merchants should take steps to remove potential vulnerabilities and provide online notices to emphasize that their website is secure. Second, consumer's overall trust was found to have a statistically significant influence on purchase intentions. This finding, which is consistent with the results of numerous prior studies, suggests that increased sales will become a reality only with enhanced consumer trust.

프로필렌의 공정안전 운전을 위한 CO2 첨가량에 따른 폭발범위 측정에 관한 연구 (A Study on the Measurement of Explosion Range by CO2 Addition for the Process Safety Operation of Propylene)

  • 최유정;허종만;김정훈;최재욱
    • 한국산학기술학회논문지
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    • 제20권7호
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    • pp.599-606
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    • 2019
  • 위험물질에 의한 제조물을 취급하는 설비와 시설은 대부분 고온, 고압으로 공정을 운전을 한다. 이로 인해 화재폭발로 인한 위험성이 증대되고 있다. 특히, 폭발 사고는 석유 화학 가스설비 등 위험물 시설의 가장 주된 위험요인으로 작용하고 있으며, 그 중, 프로필렌은 석유화학 플랜트의 기초 원료 및 첨가 중합반응에 의한 합성물질을 제조하는 현장에서 많이 사용되고 있다. 산소농도의 변화에 대한 폭발범위를 구함으로써 프로필렌을 사용하는 사업장에서 발생 될 수 있는 폭발을 예방하기 위하여 불활성 가스인 $CO_2$를 이용하여 온도와 압력의 변화에 따라 산소농도의 변화에 대한 폭발범위를 구하였다. 온도는 $25^{\circ}C$, $100^{\circ}C$, $200^{\circ}C$로 변화시켜 측정하였으며, 용기 내 압력을 $1.0kgf/cm^2.G$, $1.5kgf/cm^2.G$, $2.0kgf/cm^2.G$, $2.5kgf/cm^2.G$$CO_2$를 가압시켜 측정하였다. 폭발한계는 온도, 압력 및 산소농도와 관계가 있으며, 온도와 압력이 높아질수록 최소산소농도는 낮아지고, 산소농도가 낮아질수록 폭발범위는 좁아졌다. 또한, 최소산소농도 이하의 농도에서는 프로필렌의 증기와 점화원이 존재하여도 폭발이 발생하지 않는 것을 알 수 있다.

농업용 저수지 저수율을 이용한 충남지역 2015년 가뭄 분석 (Spatial and Temporal Analysis of Drought Using the Storage Data of Agricultural Reservoirs in Chungnam Province in 2015)

  • 김소래;장민원;김수진;배승종
    • 한국농공학회논문집
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    • 제59권2호
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    • pp.29-36
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    • 2017
  • The objective of this study was to analyze the temporal and spatial characteristics of agricultural drought by tracking the daily reservoir storage in Chungnam province. All daily records of the percent of reservoir storage from 2000 to 2015 were collected for 130 irrigation reservoirs from the RIMS (Rural Infrastructure Management System). The temporal change of province-wide average reservoir storage and the statistics showed that the annual average and minimum percent of reservoir storage in 2015 were extremely low like as those in the historical drought years of 2001 and 2012. The minimum reservoir storage on record was a 41 % at the end of September and remained far less than its historical average even until the end of the year. Furthermore, the annual average reservoir storage (68.3 %) recorded the lowest on record since 2000. In addition, about half of 130 major irrigation reservoirs in Chungnam fell into the risk of water shortage below 30 % full, and, in terms of annual minimum reservoir storage, the 79 reservoirs yielded lower storage in 2015 comparing with the measured in another drought year, 2001. On the other hand, irrigation reservoirs of comparatively worse storage condition revealed to be mostly located on the inside, such as Cheongyang-gun and Hongsung-gun. Conclusively, the low reservoir storage, still far below average even on December 2015, induced a serious concern about that more extreme drought would happen in the next spring.

해수 및 시판 수산물에서 분리한 장염비브리오균(Vibrio parahaemolyticus)의 항균제 내성 및 최소발육억제농도의 규명 (Antimicrobial Resistance and Minimum Inhibitory Concentrations of Vibrio parahaemolyticus Strains Isolated from Seawater and Commercial Fisheries)

  • 조의동;김희대;박권삼
    • 한국수산과학회지
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    • 제52권6호
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    • pp.587-595
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    • 2019
  • Eighty-three Vibrio parahaemolyticus isolates from surface seawater in Gomso Bay on the west coast of Korea, and commercial fisheries from Gunsan fisheries center were analyzed for the presence of virulence genes and susceptibility to 30 different antimicrobials. All 83 isolates were examined for the presence of two virulence genes (tdh or trh) using polymerase chain reaction; however, neither gene was found in any of the isolates. A disk diffusion susceptibility test, showed that all of the strains studied were resistant to clindamycin, oxacillin, ticarcillin, and vancomycin, and also revealed varying levels of resistance to ampicillin (98.8%), penicillin G (95.2%), streptomycin (20.5%), cefoxitin (14.5%), amikacin (6.0%), cephalothin (4.8%), and erythromycin (3.6%). However, all of the strains were susceptible to 19 other antimicrobial agents, including cefepime, cefotaxime, chloramphenicol, gentamycin, nalidixic acid, sulfamethoxazole/trimethoprim, and trimethoprim. All 83 isolates (100%) were resistant to five or more classes of antimicrobials, and two strains exhibited resistance to ten antimicrobial agents. The average minimum inhibitory concentrations against V. parahaemolyticus of clindamycin, oxacillin, ticarcillin, and vancomycin were 55.9, 98.3, 499.3, and 44.3 ㎍/mL, respectively. These results provide new insight into the necessity for seawater sanitation in Gomso Bay and commercial fisheries, and provide evidence to help reduce the risk of contamination by antimicrobial-resistant bacteria.

발사체 고체추진제의 저장 및 시험 시 안전거리 산정에 관한 연구 (A Study on the Calculation of Minimum Safety Distance during Storage and Combustion Test of Solid Propellants for Launch Vehicles)

  • 신안태;박병문;변헌수
    • Korean Chemical Engineering Research
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    • 제59권2호
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    • pp.180-185
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    • 2021
  • 한-미 미사일지침 개정으로 우주발사체에 대한 고체추진제 사용 제한이 완전히 해제 됐다. 고체추진제는 1단형 과학로켓 KSR-1과 같이 고체추진제 로켓으로 활용 가능하고, 액체연료 발사체의 추력증강 부스터로도 활용 가능하다. 고체추진제는 액체추진제에 비하여 폭발 위험성이 낮은 장점이 있지만 브라질 알칸타라 발사장 폭발사고와 같이 사고가 일어나면 대형 인명사고로 이어질 수 있다. 이와 같은 대형 인명사고를 예방하기 위해서는 고체추진제의 저장 및 시험 시 최소한의 안전거리에 대한 검토가 사업의 기획단계 부터 검토되고 반영 되어야 한다. 본 논문에서는 발사체 고체추진제를 안전하게 사용하기 위한 최소한의 안전거리를 저장시설과 시험 시로 구분하여 산정 기준 및 사례를 제시하였다.

Treatment Outcomes of Mandibular Advancement Devices in Mild, Moderate, and Severe Obstructive Sleep Apnea: A Preliminary Study

  • Hye Kyoung Kim;Mee Eun Kim
    • Journal of Oral Medicine and Pain
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    • 제48권3호
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    • pp.96-105
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    • 2023
  • Purpose: Mandibular advancement devices (MAD) are known to be insufficiently effective in all patients with obstructive sleep apnea (OSA). This study aimed to compare the treatment outcomes of MAD therapy according to OSA severity and to investigate the risk factors for the lack of response to MAD therapy. Methods: A total of 29 patients diagnosed with OSA received an adjustable two-piece MAD treatment. Sleep parameters measured with the home sleep apnea test device, including apnea-hypopnea index (AHI) and oxygen saturation (SpO2), and daytime sleepiness using the Epworth Sleepiness Scale (ESS) were retrospectively assessed both before and after the MAD treatment. Results: The patients were classified into three groups according to AHI severity: mild (n=16, AHI<15), moderate (n=6, 15≤AHI<30), and severe OSA (n=7, AHI≥30). MAD therapy significantly improved the sleep parameters (p<0.001 for AHI and p=0.004 for minimum SpO2) and daytime sleepiness (p<0.001 for ESS). Furthermore, successful outcomes (reduction in AHI>50% and AHI<10 events/h) were achieved in 83.3% and 71.4% of moderate and severe OSA cases, respectively. Of 13 patients with moderate and severe OSA, 10 were classified as responders and 3 as non-responders. The non-responders had significantly lower baseline value of SpO2 (p=0.049 for average SpO2 and p=0.007 for minimum SpO2) and higher baseline AHI (p=0.049) than the responders. Conclusions: The results of the present study suggest that MAD is effective in the majority of patients with OSA of varying severities. The success of MAD therapy does not seem to depend solely on AHI severity. In addition to AHI, minimum SpO2 may be a prognostic measure of the efficacy of MAD treatment in clinical dental practice.