• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.8
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• pp.2188-2208
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• 2023

Quality of Service (QoS) is a critical feature of Wireless Sensor Networks (WSNs) with routing algorithms. Data packets are moved between cluster heads with QoS using a number of energy-efficient routing techniques. However, sustaining high scalability while increasing the life of a WSN's networks scenario remains a challenging task. Thus, this research aims to develop an energy-balancing component that ensures equal energy consumption for all network sensors while offering flexible routing without congestion, even at peak hours. This research work proposes a Gravitational Blackhole Search Optimised splay tree routing framework. Based on the splay tree topology, the routing procedure is carried out by the suggested method using three distinct steps. Initially, the proposed GBSO decides the optimal route at initiation phases by choosing the root node with optimum energy in the splay tree. In the selection stage, the steps for energy update and trust update are completed by evaluating a novel reliance function utilising the Parent Reliance (PR) and Grand Parent Reliance (GPR). Finally, in the routing phase, using the fitness measure and the minimal distance, the GBSO algorithm determines the best route for data broadcast. The model results demonstrated the efficacy of the suggested technique with 99.52% packet delivery ratio, a minimum delay of 0.19 s, and a network lifetime of 1750 rounds with 200 nodes. Also, the comparative analysis ensured that the suggested algorithm surpasses the effectiveness of the existing algorithm in all aspects and guaranteed end-to-end delivery of packets.

• The Korean Journal of Pain
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• v.36 no.1
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• pp.51-59
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• 2023

Background: This study investigated the effect of an excess and a deficit of spinal 5-hydroxytryptamine (5-HT) on the mechanical allodynia and neuroglia activation in a rodent pain model of carrageenan inflammation. Methods: Male Sprague-Dawley rats were implanted with an intrathecal (i.t.) catheter to administer the drug. To induce an excess or deficit of 5-HT in the spinal cord, animals were given either three i.t. 5-HT injections at 24-hour intervals or a single i.t. injection of 5,7-dihydroxytryptamine (5,7-DHT) before carrageenan inflammation. Mechanical allodynia was measured using the von Frey test for 0-4 hours (early phase) and 24-28 hours (late phase) after carrageenan injection. The changes in the activation of microglia and astrocyte were examined using immunofluorescence of the dorsal horn of the lumbar spinal cord. Results: Both an excess and a deficit of spinal 5-HT had no or a minimal effect on the intensity of mechanical allodynia during the early phase but prevented the attenuation of mechanical allodynia during the late phase, which was observed in animals not treated with i.t. 5-HT or 5,7-DHT. Animals with an excess or deficit of 5-HT showed stronger activation of microglia, but not astrocyte, during the early and late phases, than did normal animals. Conclusions: Imbalance in the descending 5-HT pathway in the spinal cord could aggravate the mechanical allodynia and enhance the activation of microglia, suggesting that the spinal 5-HT pathway plays an essential role in maintaining the nociceptive processing in balance between facilitation and inhibition in inflammatory pain caused by carrageenan inflammation.

• Convergence Security Journal
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• v.22 no.2
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• pp.51-57
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• 2022

Recently, the concept of zero trust has been introduced, and it is necessary to strengthen the security elements required for the next-generation security control system. Also, the security paradigm in the era of the 4th industrial revolution is changing. Cloud computing and the cybersecurity problems caused by the dramatic changes in the work environment due to the corona 19 virus continue to occur. And at the same time, new cyber attack techniques are becoming more intelligent and advanced, so a future security control system is needed to strengthen security. Based on the core concept of doubting and trusting everything, Zero Trust Security increases security by monitoring all communications and allowing strict authentication and minimal access rights for access requesters. In this paper, we propose a security enhancement plan in the security control field through a zero trust security model that can understand the problems of the existing security control system and solve them.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.56 no.3
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• pp.331-340
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• 2023

To estimate the biological reference points, suitable for fisheries management of sandfish Arctoscopus japonicas in the East Sea of Korea, we simulated the yield-per-recruit (Y/R) from age 0 to 6 (0-2,555 days). The stimulation was based on two instantaneous natural mortality conditions: size-dependent (M_t, d^-1) and constant (M_cons, d^-1); Subsequently, the biological reference points of the two mortality conditions was compared. M_t decreased from 0.0075 d^-1 to 0.0018 d^-1 depending on growth, and M_cons remained constant at 0.0011 d^-1 for all ages. Our Y/R model showed that the maximum yield of M_cons was 14 times higher than that of the M_t. The length at first capture to maximize the harvest at the F_0.1 points of the two natural mortality conditions was L_c,t=10.2 cm (TL) and L_c,cons=17 cm (TL). We concluded that M_t was more suitable for estimating M than M_cons; this is because L_c,t showed minimal difference from the current fishing regulations (11 cm, TL), and M_t reflected more biological characteristics than M_cons. We suggest that 10.2 cm and 0.8 as the suitable length at first capture and corresponding age, respectively for efficient fisheries management of sandfish.

• Geomechanics and Engineering
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• v.35 no.6
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• pp.603-615
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• 2023

Population growth and urbanization prompted engineers to propose more sophisticated and efficient transportation methods, such as underground transit systems. However, due to limited urban space, it is necessary to construct these tunnels in close proximity to existing infrastructure like high-rise buildings and bridges. Battered piles have been widely used for their higher stiffness and bearing capacity compared to vertical piles, making them effective in resisting lateral loads from winds, soil pressures, and impacts. Considerable prior research has been concerned with understanding the vertical pile response to tunnel excavation. However, the three-dimensional effects of tunnelling on adjacent battered piled foundations are still not investigated. This study investigates the response of a single battered pile to tunnelling at three critical depths along the pile: near the pile shaft (S), next to the pile (T), and below the pile toe (B). An advanced hypoplastic model capable of capturing small strain stiffness is used to simulate clay behaviour. The computed results reveal that settlement and load transfer mechanisms along the battered pile, resulting from tunnelling, depend significantly on the tunnel's location relative the length of the pile. The largest settlement of the battered pile occurs in the case of T. Conversely, the greatest pile head deflection is caused by tunnelling near the pile shaft. The battered pile experiences "dragload" due to negative skin friction mobilization resulting from tunnel excavation in the case of S. The battered pile is susceptible to induced bending moments when tunnelling occurs near the pile shaft S whereas the magnitude of induced bending moment is minimal in the case of B.

• Journal of Animal Reproduction and Biotechnology
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• v.39 no.1
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• pp.19-30
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• 2024

Background: Although an understanding of the proliferation and differentiation of fish female germline stem cells (GSCs) is very important, an appropriate threedimensional (3D) research model to study them is not well established. As a part of the development of stable 3D culture system for fish female GSCs, we conducted this study to establish a 3D aggregate culture system of ovarian cells in marine medaka, Oryzias dancena. Methods: Ovarian cells were separated by Percoll density gradient centrifugation and two different cell populations were cultured in suspension to form ovarian cell aggregates to find suitable cell populations for its formation. Ovarian cell aggregates formed from different cell populations were evaluated by histology and gene expression analyses. To evaluate the media supplements, ovarian cell aggregate culture was performed under different media conditions, and the morphology, viability, size, gene expression, histology, and E2 secretion of ovarian cell aggregates were analyzed. Results: Ovarian cell aggregates were able to be formed well under specific culture conditions that used ultra-low attachment 96 well plate, complete mESM2, and the cell populations from top to 50% layers after separation of ovarian cells. Moreover, they were able to maintain minimal ovarian function such as germ cell maintenance and E2 synthesis for a short period. Conclusions: We established basic conditions for the culture of O. dancena ovarian cell aggregates. Additional efforts will be required to further optimize the culture conditions so that the ovarian cell aggregates can retain the improved ovarian functions for a longer period of time.

• Korean Journal of Radiology
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• v.22 no.1
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• pp.97-105
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• 2021

Objective: The present study aimed to investigate the association between myocardial blood flow (MBF) quantified by dynamic CT myocardial perfusion imaging (CT-MPI) and the increments in heart rate (HR) after stress in patients without obstructive coronary artery disease. Materials and Methods: We retrospectively included 204 subjects who underwent both dynamic CT-MPI and coronary CT angiography (CCTA). Patients with more than minimal coronary stenosis (diameter ≥ 25%), history of myocardial infarction/revascularization, cardiomyopathy, and microvascular dysfunction were excluded. Global MBF at stress was measured using hybrid deconvolution and maximum slope model. Furthermore, the HR increments after stress were recorded. Results: The median radiation dose of dynamic CT-MPI plus CCTA was 5.5 (4.5-6.8) mSv. The median global MBF of all subjects was 156.4 (139.8-180.4) mL/100 mL/min. In subjects with HR increment between 10 to 19 beats per minute (bpm), the global MBF was significantly lower than that of subjects with increment between 20 to 29 bpm (153.3 mL/100 mL/min vs. 171.3 mL/100 mL/min, p = 0.027). This difference became insignificant when the HR increment further increased to ≥ 30 bpm. Conclusion: The global MBF value was associated with the extent of increase in HR after stress. Significantly higher global MBF was seen in subjects with HR increment of ≥ 20 bpm.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.8
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• pp.1172-1180
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• 2013

Two experiments were conducted to determine the standardized ileal digestible (SID) lysine (Lys) requirement and the ideal SID threonine (Thr) to Lys ratio for finishing barrows. In Exp. 1, 120 barrows with an average body weight of $72.8{\pm}3.6$ kg were allotted to one of six dietary treatments in a randomized complete block design conducted for 35 d. Each diet was fed to five pens of pigs containing four barrows. A normal crude protein (CP) diet providing 15.3% CP and 0.71% SID Lys and five low CP diets providing 12% CP with SID Lys concentrations of 0.51, 0.61, 0.71, 0.81 and 0.91% were formulated. Increasing the SID Lys content of the diet resulted in an increase in weight gain (linear effect p = 0.04 and quadratic effect p = 0.08) and an improvement in feed conversion ratio (FCR) (linear effect p = 0.02 and quadratic effect p = 0.02). For weight gain and FCR, the estimated SID Lys requirement of finishing barrows were 0.71 and 0.71% (linear broken-line analysis), 0.79 and 0.78% (quadratic analysis), respectively. Exp. 2 was a 26 d dose-response study using SID Thr to Lys ratios of 0.56, 0.61, 0.67, 0.72 and 0.77. A total of 138 barrows weighing $72.5{\pm}4.4$ kg were randomly allotted to receive one of the five diets. All diets were formulated to contain 0.61% SID Lys (10.5% CP), which is slightly lower than the pig's requirement. Weight gain was quadratically (p = 0.03) affected by SID Thr to Lys ratio while FCR was linearly improved (p = 0.02). The SID Thr to Lys ratios for maximal weight gain and minimal FCR and serum urea nitrogen (SUN) were 0.67, 0.71 and 0.64 using a linear broken-line model and 0.68, 0.78 and 0.70 using a quadratic model, respectively. Based on the estimates obtained from the broken-line and quadratic analysis, we concluded that the dietary SID Lys requirement for both maximum weight gain and minimum FCR was 0.75%, and an optimum SID Thr to Lys ratio was 0.68 to maximize weight gain, 0.75 to optimize FCR and 0.67 to minimize SUN for finishing barrows.

• Journal of the Korea Concrete Institute
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• v.22 no.3
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• pp.381-388
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• 2010

In this study, characteristics of the seismic response of the non-earthquake resistant reinforced concrete (RC) frame were identified. The test building is designed to withstand only gravity loads and not in compliance with modern seismic codes. Smooth bars were utilized for the reinforcement. Members are provided with minimal amount of stirrups to withstand low levels of shear forces and the core concrete is virtually not confined. Columns are slender and more flexible than beams, and beam-column connections were built without stirrups. Through the modeling of an example RC frame, the feasibility of the fiber elementbased 3D nonlinear analysis method was investigated. Since the torsion is governed by the fundamental mode shape of the structure under dynamic loading, pushover analysis cannot predict torsional response accurately. Hence, dynamic response history analysis is a more appropriate analysis method to estimate the response of an asymmetric building. The latter method was shown to be accurate in representing global responses by the comparison of the analytical and experimental results. Analytical models without rigid links provided a good estimation of reduced stiffness and strength of the test structure due to bond-slip, by forming plastic hinges closer to the column ends. However, the absence of a proper model to represent the bond-slip poased the limitations on the current inelastic analysis schemes for the seismic analysis of buildings especially for those with round steel reinforcements. Thus, development of the appropriate bond-slip model is in need to achieve more accurate analysis.

• Journal of Korean Association for Spatial Structures
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• v.11 no.3
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• pp.95-103
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• 2011

Among structural systems for complex-shaped tall buildings, diagrid system is widely used because of its structural efficiency and beauty of form. Recently, mega frame is favorably employed as a suitable structural system for skyscrapers because this structural system has sufficient stiffness against the lateral forces by combination of mega members which consist of many columns and girders. Diagrid mega frame system is expected to be promising structural system for future super tall buildings. However, it takes tremendous analysis times and engineer's efforts to predict the structural behavior of tall buildings applied with diagrid mega frame system because the diagrid mega frame structure has significant numbers of elements and nodes. Therefore, efficient analytical method for all buildings applied with diagrid mega frame system has been proposed in this study to reduce the efforts and time required for the analysis and design of diagrid mega frame structure. To this end, an efficient modelling technique using the characteristics of diagrid mega frame structures and an efficient analytical model using minimal DOFs by the matrix condensation method were proposed in this study. Based on the analysis of an example structure, the effectiveness and accuracy of the proposed method have been verified by the comparison between the results of the proposed method and the conventional method.