• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup2
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• pp.19-24
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• 2016

Quitline activity in Rajasthan, India is a voluntary activity of Rajasthan Cancer Foundation (RCF) since April 2013. To kick-off, it took the benefit of the State Government- PIRAMAL SWASTHYA (PS)1 collaborative 104 Health Information Helpline that existed already in public-private partnership. It is a reactive quitline that helps callers through the counselors and nursing staff trained specifically through the weekly sessions held by the first author, the RCF resource on quitline. Besides structuring of the scripts for primary intervention and follow-ups after 1 week, 1 month, 6 months and a year, he also monitors calls, advices and coordinates with the supervisors to manage and analyze the data base, and reports to the PS lead at the Jaipur Center on overall performance and to plan strategic communication with the State Government on its outcomes. The quitline has limitations of its informal existence through a voluntary effort of RCF, no specific resource allocation, suboptimal data management, minimal awareness in the masses due to poor IEC (Information, Education and Communication; except its efforts made by RCF in last 1 year through the government-run State TV and City Radio) and staff shortage and its attrition due to lack of plan for career advancement. Despite these challenges in the year 2013, the quit line has registered a quit rate (for complete abstinence) of 19.93% amongst 1525 callers. The quit rate were 58.01% (304/ 524) among the responders at the 3rd follow-up at 18 months (in September 2014)2. In view of an increase in quit rate by 5- 9 times over the prevailing quit rate in the former ever daily users [both smokers and the users of smokeless tobacco (SLT)], efforts are being made by RCF in concurrence with PS to have this cost-effective model established formally with optimal resource allocation in collaboration with willing agencies (the State and Central Governments and the International Quitline Agencies) and its replication in 4 more states where PS is collaborating with the respective state governments similarly (Assam, Chhattisgarh, Jharkhand and Karnataka).

• The Transactions of the Korean Institute of Power Electronics
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• v.6 no.2
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• pp.115-124
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• 2001

In this paper, authors propose a new nonlinear rotor flux observer for rotor field oriented control of an induction motor which is designed based on the extended Luenberger Observer theory. Extended Luenberger Observer requires minimal solution of nonlinear partial differential equation on its coordinate transformation and linearization needed on a nonlinear observer design in general. The proposed rotor flux observer is derived from the 2 phase model of induction motor on the orthogonal coordination and it has the reduce gain matrix. Simulation and experimentation were performed under the conventional indirect vector control and direct vector control with the proposed observer at different rotor resistance. Simulation results show that the convergence of the proposed observer is influenced by the chosen eigenvalues. Experimentation results on load operation show the direct vector control with the proposed observer is better than the indirect vector control to maintain the characteristics of the vector control.

• The Transactions of the Korea Information Processing Society
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• v.6 no.8
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• pp.2196-2203
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• 1999

This paper describes the bus scheduling problem and register optimization method in datapath synthesis. Scheduling is process of operation allocation to control steps in order to minimize the cost function under the given circumstances. For that purpose, we propose some formulations to minimize the cost function for bus assignment to get an optimal and minimal cost function in hardware allocations. Especially, bus and register minimization technique are fully considered which are the essential topics in hardware allocation. Register scheduling is done after the operation and bus scheduling. Experiments are done with the DFG model of fifth-order digital ware filter to show its effectiveness. Structural integer programming formulations are used to solve the scheduling problems in order to get the optimal scheduling results in the integer linear programming environment.

• The Transactions of the Korea Information Processing Society
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• v.7 no.5
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• pp.1464-1473
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• 2000

In this paper, we analyze the cycle property of the (n,k)-star graph that has an attention as an alternative interconnection network topology in recent years. Based on the graph-theoretic properties in (n,k)-star graphs, we show the pancyclic property of the graph and also present the corresponding algorithm. Based on the recursive structure of the graph, we present such top-down approach that the resulting cycle can be constructed by applying series of "dimension expansion" operations to a kind of cycles consisting of sub-graphs. This processing naturally leads to such property that the resulting cycles tend to be integrated compactly within some minimal subset of sub-graphs, and also means its applicability of another classes of the disjoint-style cycle problems. This result means not only the graph-theoretic contribution of analyzing the pancyclic property in the underlying graph model but also the parallel processing applications such a as message routing or resource allocation and scheduling in the multi-computer system with the corresponding interconnection network.

• Journal of the Korean Institute of Intelligent Systems
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• v.8 no.3
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• pp.33-40
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• 1998

This paper presents an Modified Orthogonal Neural Network(MONN), new modified model of Orthogonal Neural Network(0NN) based on orthogonal functions, and applies it to nonlinear system approximator. ONN proposed by Yang and Tseng, doesn't have the problems of traditional multilayer feedforward neural networks such as the determination of initial weights and the numbers of layers and processing elements. And tranining of ONN converges rapidly. But ONN cannot adapt its orthogonal functions to a given system. The accuracy of ONN, in terms of the minimal possible deviation between system and approximator, is essentially dependent on the choice of basic orthogonal functions. In order to improve ability and effectiveness of approximate nonlinear systems, MONN has an input transformation layer to adapt its basic orthogonal functions to a given nonlinear system. The results show that MONN has the excellent performance of approximate nonlinear systems and the input transfnrmation makes the ability of MONN better than one of ONN.

• Journal of Korean Society for Quality Management
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• v.48 no.2
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• pp.269-282
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• 2020

Purpose: The practical design for experiments with mixtures of q components is consisted in the four types of design points, vertex, center of edge, axial, and center points in a (q-1)-dimensional simplex space. We propose a sequential method for the successful construction of the design space in Quality by Design (QbD) by allowing the different number of replicates at the four types of design points in the practical design when the quadratic canonical polynomial model is assumed. Methods: To compare the mixture designs efficiency, fraction of design space (FDS) plot is used. We search for the practical mixture designs whose the minimal half-width of the tolerance interval per a standard deviation, which is denoted as d₂, is less than 4.5 at 0.8 fraction of the design space. They are found by adding the different number of replicates at the four types of the design points in the practical design. Results: The practical efficient mixture designs for the number of components between three and five are listed. The sequential method to establish a design space is illustrated with the two examples based on the simulated data. Conclusion: The designs with the center of edge points replications are more efficient than those with the vertex points replication. We propose the sample size of at least 23 for three components, 28 for four components, and 33 for the five components based on the list of efficient mixture designs.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.11a
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• pp.99-113
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• 1996

Taurine, a ${\beta}$-amino acid, plays an important role as a neuromodulator and is necessary for the normal development of the brain. Since de novo synthesis of taurine in the brain is minimal and in vivo studies suggest that taurine does not cross the blood-brain barrier, the blood-cerebrospinal fluid (CSF) barrier is likely to play a role in taurine transport between the central nervous system and the systemic circulation. Therefore, we examined in vivo elimination of taurine from the CSF in the rat to characterize in vivo kinetics of elimination for taurine from the CSF is consistent with the in vitro study. Using a stereotaxic device, cannulaes were placed into the lateral ventricle and the cisterna magna of the rat. Radio-labelled taurine and inulin (a marker of CSF flow) were injected into the lateral ventricle, and the concentrations of the labelled compounds in the CSF were monitored for up to 3 hrs in the cisterna magna. The apparent clearance of taurine from CSF was greater than the estimated CSF flow (p<0.005), indicating that there is a clearance process in addition to the CSF flow. Taurine distribution into the choroid plexus was at least 10 fold higher than that found in other brain areas (e.g., cerebellum, olfactory bulb and cortex). When unlabelled taurine was co-administered with radio-labelled taurine, the apparent clearance of the labeled taurine was reduced (p<0.01), suggesting a saturable disposition of taurine from CSF. Distribution of taurine into the choroid plexus, cerebellum, olfactory bulb and cortex was similarly diminished, indicating that the saturable uptake of taurine into these tissues is responsible for the non-linear disposition. A pharmacokinetic model involving first order elimination and saturable distribution described these data adequately. The Michaelis-Menten rate constant estimated from in vivo elimination study is similar to that obtained in the in vitro uptake experiment Collectively, our results demonstrate that taurine is transported in the choroid plexus via a taurine is cleared from the CSF via a saturable process. This process may be functionally relevant to taurine homeostasis in the brain.

• Restorative Dentistry and Endodontics
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• v.22 no.1
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• pp.464-469
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• 1997

The radiopacity of glass ionomer cements is quite variable. The use of a poorly radiopaque material as a base under other restorative materials can mislead the dentist to a diagnosis of recurrent decay. This study investigates the radiopacity of these materials and proposes a minimal radiopacity under which a material should not be used as a base or liner. It is important to determine the radiopacity of glass ionomer dental materials so that the clinician can appreciate the type of restorative materials used when radiographically evaluation the possibility of recurrent dental caries. In this study, radiopacity of Vitrement and Chemfil was compared with that of Cavalite, Miracle mix and polycarboxylate cement. Tooth model of artificial cavity preparation for diagnosis of recurrent caries was omitted. Radiopacity of each material was measured using relatives between thickness and radiopacity of Aluminium step wedge. The results were as follows : 1. Radiopacity of Vitrement was some higher than enamel. 2. Chemfil, restorative glass ionomer, was less radiopaque than enamel. 3. In order of higher radiopacity than enamel, Miracle mix was highest and was followed by polycarboxylate cement, Cavalite and Vitremer. 4. Vitremer, the Glass Ionomer Cement, is useful to detection of recurrent caries, because it is slightly higher radiopaque than enamel. So, it is suitable for restorative material and luting cement.

• Journal of Pharmacopuncture
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• v.18 no.3
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• pp.57-62
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• 2015

Objectives: The purpose of this study was to examine the single-dose intravenous toxicity of Guseonwangdo-go glucose 5% pharmacopuncture (GWG5). Methods: Forty Sprague-Dawley rats were divided into four groups of five males and five females per group: an intravenous (IV) injection of 1.0 mL of normal saline solution per animal was administered to the control group; IV injections of 0.1, 0.5, and 1.0 mL of GWG5 per animal were administered to the experimental groups (G: 0.1, G: 0.5, and G: 1.0). Observation of clinical signs and body weight measurements were carried out for 14 days following the injections. At the end of the observation period, hematological, biochemical, and histopathological tests, as well as necropsy examinations, were performed on the injected parts. Results: No mortalities or adverse clinical signs were observed in any of the groups. The body weights of all groups continuously increased. In the hematological and the biochemical tests, females in G-0.1 had minimal changes, but those changes were not dose dependent. On necropsy examination, no abnormalities were observed. In the histopathological test, focal inflammatory cell infiltrations were observed in two female rats, one in the control group and one in G-1.0. Also, one female rat in the control group had an epidermis crust. These changes were concluded to have been caused by the insertion of the needle into a vein. Conclusion: The above findings suggest that the lethal dose of GWG5 administered via IV injection is more than 1.0 mL per animal in both male and female rats. Further studies are needed to establish more detailed evidence of its toxicity.

• Journal of Biomedical Engineering Research
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• v.16 no.4
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• pp.499-506
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• 1995

A new numerical method estimated three dimensional shape of the internal surface of the stomach by analyzing the shading data of endoscopic image. First analyzed was the inherent instrumentational characteristics of the endoscope system, followed by the analysis of the stomach surface properties, both of which affected the imaging properties. We employed these prior informations to implement the iterative algorithm of shading analysis based on Hom's variational approach. The present algorithm was validated by performing simulation on a $256{\times}320$ image data chosen from original $512{\times}512$ image of the stomach surface model. The best 3-dimensional estimation of the surface was achieved with the Lagrangian multiplier, of 0.3, when the algorithm best converged showing minimal estimation error.