• 대한핵의학회지
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• 제36권2호
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• pp.91-101
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• 2002

목적: 본 연구의 목적은 첫째, 알쯔하이머형 치매의 국소뇌혈류량이 일정 시간이 지난 후 감소되는 양상을 voxel based 분석을 통해 확인하고자 하였다. 둘째, 이들 환자에 있어서 두뇌 특정부위가 임상에서 흔하게 쓰이는 간이정신상태검사인 MMSE-K(Mini-Mental State Examination, Korean version)의 수행과 상관을 보이는 영역이 있는지 살펴보고자 하였다. 대상 및 방법: Tc-99m HMPAO SPECT를 이용해서 9명의 probable 알쯔하이머형 치매 환자군에게 평균 1.8년의 기간을 두고 각각 두 번의 영상(기저영상과 추적검사 영상)을 얻었고, 이를 각각 9명의 정상노인으로부터 얻은 영상과 비교 분석하였다. 각 영상은 공간정규화 이후 소뇌의 활성화에 따라 계수 정규화되었고, SPM99를 사용하여 voxel based 분석을 하였다. 결과: 대조군에 비하여 환자군에서 뇌혈류량의 감소를 보이는 영역이, 기저검사에서 주로 두정측두영역인데 비하여 추적검사시에는 전두엽 영역으로 확대되었다. MMSE-K 점수와 가장 높은 상관관계를 보이며 뇌혈류가 감소하는 영역은 기억의 부호화와 관련된다고 알려진 좌측 중/하전두엽과 중측두엽, 그리고 후대상회와 전설소엽이었다. 결론: probable 알쯔하이머형 치매 환자군에게 있어서 질병이 진전됨에 따라 변하는 뇌혈류 감소가 두정엽에서 전두엽을 포함하였다. 특히 좌측전두엽의 혈류량 감소는 MMSE-K로 측정된 인지기능 수행 저하와 유의미한 상관을 보임이 확인되었다. 본 연구는 SPM을 이용한 이러한 분석방법을 통하여 핵의학 영상을 알쯔하이머형 치매의 경과추적과 진단의 유용한 도구로 사용할 수 있음을 보인다.

• 지역사회간호학회지
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• 제19권3호
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• pp.368-377
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• 2008

Purpose: The Purpose of this study was to investigate the effects of perceived stress on cognition in the community elderly. Methods: This was a descriptive study. Data were collected using individual-based interviews from 40 senior residents at the hall for the elderly in S City. The period of data collection was from June 19 to July 7, 2006. The tools of data collection were Mini-Mental State Examination (Folstein, Folstein, & McHugh, 1975) and Perceived Stress Scale (Cohen, Kamarck, & Mermelstein, 1983). Results: Cognition showed significant differences according to gender education, and regular exercise. Cognition was significantly correlated to stress and age. Stress was significantly correlated to orientation, recall, and attention/calculation. In the results of stepwise multiple regression, factors affecting cognition were stress, age, and gender. Conclusion: It is necessary to prepare health promotion programs that can reduce stress level in the community elderly.

• 동의신경정신과학회지
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• 제28권4호
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• pp.391-399
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• 2017

Objectives: To determine the effects of Korean medicine on behavioral and psychological symptoms of dementia (BPSD) of an Alzheimer's disease (AD) patient. Methods: A 85-year old female patient diagnosed with AD was treated with herbal medicine formula Chungsimyeonja-tang (淸心蓮子湯), Woohwangchungsim-won (牛黃淸心元), and acupuncture. Korean version of Mini-mental State Examination (MMSE-K) scores were used at baseline and post treatment as outcome measures to evaluate clinical symptoms of the patient. Results: Improvements in MMSE-K post treatment scores were observed compare to those at baseline. BPSD were also alleviated. Such changes were visually noticeable. Conclusions: Herbal medicine and acupuncture treatment were effective in alleviating symptoms of AD. Further studies with a larger sample size and randomized clinical trials are needed to obtain more reliable and valid treatment outcomes.

• 국제물리치료학회지
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• 제4권2호
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• pp.545-551
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• 2013

The purpose of this study is to determine the correlations between problematic behaviors and activities of daily living(ADL) targeting 106 demented elderly people hospitalized in a geriatric hospital. To examine the cognitive function of the subjects, the study used Korean Mini Mental State Examination(K-MMSE). For problematic behaviors and ADL, the study collected data based on Patient Assessment Forms in the geriatric hospital. Among problematic behaviors, apathy/indifference had the highest correlation with the items of ADL. Irritability/lability, agitation/aggression, depression/ dysphoria, night-time behavior and wandering also showed to be correlated to items of ADL(p<.05). This study demonstrated that cognitive function, problematic behaviors and ADL of the demented elderly hospitalized in the geriatric hospital are correlated to each other.

• 동의신경정신과학회지
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• 제17권1호
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• pp.145-152
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• 2006

The purpose of this study was to investigate the clinical application of oriental medical therapy to Pick's disease We treated the patient with oriental medical therapy. The recovery of the dementia was evaluated by Korean-Mini Mental State Examination(MMSE-K), Korean-dementia Rating Scale(K-DRS) & Barthel ADL Index.(ADL) The applicability of oriental medical therapy has positive effects on the patient with Pick's disease. The Sum of MMSE-K score was increased. K-DRS & ADL were also promoted.

• 동의신경정신과학회지
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• 제24권4호
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• pp.385-392
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• 2013

This case report presents a 34-year-old female patient. Her chief complaints are akinetic mutism and cognitive dysfunctions. We have diagnosed her with leukoencephalopathy. She was treated with Korean traditional herbal medicines (Joojackwhan) for 33 days continuously. The effects of treatment were measured by the Korean Mini - Mental State Examination and Modified Bathel Index. After treatment, her chief complaints have been improved. Furthermore, the K-MMSE, MBI scores increased. From this case, we deduced that the Korean traditional herbal medicines (Joojackwhan) could be effective for cognitive dysfunctions and akinetic mutism caused by leukoencephalopathy.

• International Journal of Contents
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• 제5권3호
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• pp.86-90
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• 2009

The Purpose of this study was to investigate correlations between the Mini-Mental State Examination (MMSE) and the Functional Independence Measure (FIM) in strokes. The data collected retrospectively from fifty-five stroke rehabilitation patients. The MMSE and FIM at the time of admission and discharge were obtained from patients' medical records. Firstly, Pearson correlation coefficients of the MMSE score at the time of admission revealed $0.286{\sim}0.747$ with FIM at the time of discharge (p<0.05). Also, the change of MMSE score significantly correlated with the change of total FIM scores in strokes (r=0.409, p<0.05). Because the MMSE scores at the time of admission and FIM at the time of discharge are correlated, the MMSE scores can be used to predict the FIM at the time of discharge and establish a rehabilitation program.

• 동의신경정신과학회지
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• 제22권4호
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• pp.157-168
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• 2011

Objectives : In this case report, we will present a patient with dementia with Lewy bodies improved by application of oriental medical treatments. Methods : A 82 year-old female patient has been suffered by dementia with Lewy bodies for 7~8 years. We treated the patient with Herbal medication and acupuncture. The effects of treatment were measured by MMSE-K (Mini-Mental State Examination-K). Results : As a result of oriental treatments, the quality of sleep was improved, also the level of cognition was improved. Conclusions : These results suggest that oriental treatments have an effect on Dementia with Lewy bodies.

• 동서간호학연구지
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• 제16권2호
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• pp.131-137
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• 2010

Purpose: The purpose of this study was to investigate the relationship between depression status and cognitive function in the community female aged. Methods: This was a descriptive study. Data were collected using individual-based interviews from 120 senior female residents in the Hall for the aged in the city of S. The length of time for data collection was from June 18 to 29, 2007. The tool of data collection was Korean Version of Mini-Mental State Examination (Kwon & Park, 1989), Short-form Geriatric Depression Scale (Bae, 1996). Results: Depression & cognition showed significant differences according to age, regular exercise. The depression group scored significantly lower than the normal group in total score of cognition, orientation, memory recall. Conclusion: It is necessary to prepare the composite programs, which can improve not only cognition but depression in the community female aged.\

• 성인간호학회지
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• 제28권6호
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• pp.669-679
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• 2016

Purpose: The purpose of this study was to explore the reported good service experiences from the perspective of elderly residents of long-term care facilities. Methods: Of those residents who are 65 years old or older, 14 residents whose length of stay were one month or longer and scores of the K-Mini Mental State Examination were 15 or higher were interviewed. The interview data formed the basis for the empirical statements about the reported nature of patients' experiences as residents of long-term care facilities. These data were used in concept mapping. Results: Through multidimensional scaling analysis and hierarchical cluster analysis, 62 core statements, two dimensions, and six clusters of good service experiences were derived. The two dimensions were classified as 'care centered-participation centered services' and as 'physical-emotional services.' Six cluster themes emerged as good service experiences: 'safety of care and treatment', 'responsible and supportive staff', 'comfort of living environment', 'mental well-being', and 'respect and communication'. Conclusion: The result of the study provides information about what experiences are important to older adults with cognitive impairment. The concept map can be used to develop a patient experience index for the elderly residents of long-term care facilities.