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Comparison of tracheal intubation using the Miller blade versus Macintosh blade in difficult airway: A manikin study among novice intern doctors (기도확보가 어려운 상황에서 Miller blade와 Macintosh blade를 이용한 기관내삽관의 비교 : 숙련되지 않은 인턴을 대상으로 한 마네킨 연구)

  • Lee, Mi-Lim;Kim, Chul-Tae;Lee, Hyo-Cheol
    • The Korean Journal of Emergency Medical Services
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    • v.22 no.3
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    • pp.35-45
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    • 2018
  • Purpose: The purpose of this study was to compare laryngoscopic views and ease of use and success of intubation, via the percentage of glottic opening (POGO) scale when using the Miller blade and Macintosh blade in paraglossal approach. Methods: Forty intern doctors were randomized for laryngoscopy to be performed in a crossover manner. They performed endotracheal intubation with Miller blade and Macintosh blade in two airway scenarios: normal airway and difficult airway with edema. We observed the rate of successful intubation, time required for visualizing the glottis, time to complete endotracheal intubation, ease of intubation, and the POGO scale. Results: In the normal airway, there was no difference in intubation between the two endoscopes. In the difficult airway, the time for visualizing the glottis (7.80 versus 10.24 sec; p=.006), the time to tube passage (19.38 versus 23.03 sec; p=.038) and the time to complete endotracheal intubation (21.84 versus 28.54 sec; p=.022) with Miller blade was shorter than with Macintosh blade. The POGO scale(%) of the Miller blade was higher than that of the Macintosh blade's (62.25 versus 56.32; p=.030). Conclusion: Compared to the Macintosh blade, Miller blade provided better visualization of the glottis and POGO scale, and faster time to completion of endotracheal intubation.

A Case Report of Miller Fisher Syndrome (밀러피셔증후군의 불면증 환자 치험 1례)

  • Cha, Hye-Jin;Lee, Ji-Won;Seo, Young-Min;Seo, Deok-Won;Park, Se-Jin
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.3
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    • pp.229-236
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    • 2009
  • Objectives : This study is designed investigate the effect of oriental medial therapy on a 63 year old female patient had Miller Fisher Syndrome with sleeplessness. Methods : We experienced a case of Miller Fisher Syndrome and treated with herbal medicine, eletro-acupuncture. The effects of treatment were measured by sleeping hour, taken measurements with a ruler(eyeball movement). Results : Whole condition (ophthalmoplegia, ataxia and so on) was improved and Oriental treatment had a good effect on sleeping hour. Conclusions : Oriental medical treatments were very effective for the patient had Miller Fisher Syndrome with sleeplessness.

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Volatile Components of Lycium chinensis Miller (구기자(Lycium chinensis Miller)의 휘발성 성분)

  • 박원종;복진영;백순옥;한상빈;주현균
    • The Korean Journal of Food And Nutrition
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    • v.10 no.1
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    • pp.1-5
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    • 1997
  • The volatile components of Lycium chinensis Miller were isolated by simultaneous steam distillation-extraction(SDE) method and analyzed by combined GC and GC-MS. Fifty-four volatile components, including 12 alcolhols 12 esters, 7 aldehydes, 6 acids, 5 ydrocarbons, 8 ketones, 1 furan and 3 pyrazines were confirmed in the fruit of Lycium chinensis Miller. The major components were hexadecanoic acid ethyl ester, 1-octadecanone, tetrapyrazine, 2-furancarboxaldehyde and ethyl linoleate.

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Improving the performance of a Medium Speed Diesel Engine Using Miller Cycle (Miller 사이클을 이용한 중형 디젤 기관 성능 개선)

  • 김동훈;김기두;하지수;김호익;김주태
    • Journal of Advanced Marine Engineering and Technology
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    • v.26 no.2
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    • pp.248-255
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    • 2002
  • Miller cycle was studied and analyzed by engine performance simulation to achieve very low fuel consumption and to meet the IMO NOx regulation on a medium speed diesel engine. Based on the performance simulation results the intake valve closing time for HYUNDAI HiMSEN 6H21/32 engine was set at 0deg.ABDC(After Bottom Dead Center). Also, the simulation results indicated that significant NOx reduction could be achieved with low reduction of fuel consumption. The performance simulation investigated the effect of compression ratio and turbocharger on fuel consumption and NOx concentration in combination with Miller cycle. The results indicated a significant reduction of fuel consumption with keeping NOx concentration. The results of performance simulation were compared with measured data to verify simulation results. The comparison showed the maximum error was 2.34% in exhaust temperature. Also, the experimental result showed that improvement in BSFC(Brake Specific Fuel Consumption) was 5.8g/kwh with keeping NOx level similar to simulation result.

Anti-inflammatory and Antioxidant Effects of Zizyphus jujuba Miller var. inermis extracts (대추 추출물의 항산화 및 아토피 피부염 관련 항염증 효과)

  • Hong, Chang-Eui;Chun, Young-Hee;Lyu, Su-Yun
    • Korean Journal of Pharmacognosy
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    • v.50 no.2
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    • pp.86-95
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    • 2019
  • In the present study, the effect of Z. jujuba Miller var. inermis Rehder extracts on the secretion of atopic dermatitis (AD)-related cytokines and hyaluronidase activity was investigated. We prepared four fractions, butylene glycol (JB), ethanol (JE), and water (JW), with Z. jujuba Miller var. inermis extracts. JW significantly reduced the secretion of interleukin-8 and JE reduced the secretion of tumor necrosis factor-alpha in human keratinocyte HaCaT cells. Also, hyaluronidase activity was measured by enzyme assay and the fractions inhibited the activity in a dose-dependent manner. In addition, the human dermal fibroblast, HDF-n cells were treated with the extracts and antioxidant activities were measured. The results showed that the extracts increased the free radical scavenging activity and the superoxide dismutase activity. Taken together, Z. jujuba Miller var. inermis extracts reduced the secretion of AD-related cytokines and inhibited the hyaluronidase. In addition, the extracts showed antioxidant activity.

Analysis of Research Trends in Korean Medicine Treatment for Miller-Fisher Syndrome in Korea (밀러피셔 증후군의 한의학적 치료에 대한 국내 연구 현황)

  • Hyeon Kyu Choi;Young Il Kim
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.17 no.2
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    • pp.119-130
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    • 2022
  • Objectives This study aimed to analyze the Korean medical treatment methods for Miller-Fisher syndrome from January 01, 2000 to December 31, 2021. Methods Six online databases (KISS, SCIENCEON, DBpia, RISS, KMBASE, and KoreaMed) were searched for clinical studies related to Miller-Fisher syndrome. Results Thirteen case reports were selected out of the 85 studies, and a total of 13 cases were analyzed. There were five kinds of Korean medicine treatment that were used in these studies. Acupuncture and herbal medicine were the most used interventions. Conclusions Korean medical treatment is found to be effective for Miller-Fisher syndrome. Although several limits remain, we expect that further research will be conducted to provide a better level of evidence.

A Case Report of Atypical Miller-Fisher Syndrome (비전형적 Miller-Fisher 증후군 1례)

  • Lee, Seung Min;Ji, Young Seung;Lee, Chang Woo;Jeon, Ju Hyun;Kim, Jung Ho;Kim, Young Il
    • Journal of Acupuncture Research
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    • v.29 no.6
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    • pp.105-110
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    • 2012
  • Objectives : This study is designed to investigate the effect of oriental medical therapy on a 10 year old male patient had atypical Miller-Fisher syndrome with ophthalmoplegia and ptosis. Methods : We experienced a case of atypical Miller-Fisher syndrome and treated with acupuncture treatment, electro-acupuncture therapy, herbal medicine. The effect of treatment were evaluated with pictures of palpebra and eyeball movement. Results : After oriental medical treatment, ophthalmoplegia and ptosis was improved. Conclusion : Acupuncture, electro-acupuncture therapy and herbal medication is promising treatment for atypical Miller-Fisher syndrome with ophthalmoplegia and ptosis.

Waardenburg Syndrome Type IV De Novo SOX10 Variant Causing Chronic Intestinal Pseudo-Obstruction

  • Hogan, Anthony R.;Rao, Krishnamurti A.;Thorson, Willa L.;Neville, Holly L.;Sola, Juan E.;Perez, Eduardo A.
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.22 no.5
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    • pp.487-492
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    • 2019
  • Waardenburg syndrome (WS) type IV is characterized by pigmentary abnormalities, deafness and Hirschsprung's disease. This syndrome can be triggered by dysregulation of the SOX10 gene, which belongs to the SOX (SRY-related high-mobility group-box) family of genes. We discuss the first known case of a SOX10 frameshift mutation variant defined as c.895delC causing WS type IV without Hirschsprung's disease. This female patient of unrelated Kuwaiti parents, who tested negative for cystic fibrosis and Hirschsprung's disease, was born with meconium ileus and malrotation and had multiple surgical complications likely due to chronic intestinal pseudo-obstruction. These complications included small intestinal necrosis requiring resection, development of a spontaneous fistula between the duodenum and jejunum after being left in discontinuity, and short gut syndrome. This case and previously reported cases demonstrate that SOX10 gene sequencing is a consideration in WS patients without aganglionosis but with intestinal dysfunction.

Frequency Response Analysis of Common-Source Amplifier Using the Exact Modeling of Miller Effect (밀러 효과의 정확한 모델링을 이용한 공통 소스 증폭기의 주파수 특성 연구)

  • Yi, Soonjai;Lee, Dong-Keon;Jeong, Hang-Geun
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.1
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    • pp.172-178
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    • 2014
  • This paper presents a new model of the Miller effect. The new Miller effect model is obtained from the accurate AC gain which includes the effect of the output capacitance of the common-source (CS) amplifier. The new Miller effect model consists of the series connection of a capacitance and a parallel RC circuit, one at the input and the other at the output. The frequency response obtained by the new Miller effect model is equal to that obtained from the original circuit. Even though the new model is complicated, the 3-dB frequency can be easily estimated by using the open-circuit time constants method without the node analysis.

A Case of Delayed Facial Palsy and Dizziness in Miller-Fisher Syndrome (Miller-Fisher 증후군에서 나타난 지연형 안면마비 및 현훈 치험 1례)

  • Song, Mi-Sa;Yoon, Hwa-Jung;Ko, Woo-Shin
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.3
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    • pp.254-261
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    • 2019
  • Objective : Miller-Fisher syndrome(MFS) is a type of acute inflammatory polyneuropathy, a disease characterized by abnormal muscle coordination, absence of tendon reflexes, and paralysis of the eye muscle. This study is to report a case of delayed facial palsy and dizziness in Miller-Fisher syndrome, treated with traditional Korean medicine. Methods : A 57-year-old male was diagnosed with Miller-Fisher syndrome accompanied by neurological symptoms such as right facial palsy and dizziness. He received traditional Korean medicine treatment such as acupuncture(including pharmacopuncture, needle embedding therapy, electroacupuncture) and herbal medicine for 17 days. Results : Each neurological symptoms were improved after traditional Korean medicine. In case of facial palsy, House Brackmann Grading System was reduced form grade 3 to grade 2, and Sunnybrook Scale was improved from 39 to 55. Also, other symptoms such as dizziness and headache was also improved. Conclusions : This case report suggests that traditional Korean medicine may have a role in treating neurological symptoms such as facial palsy and dizziness in patient diagnosed with Miller-Fisher syndrome.