• Journal of Korean Neurosurgical Society
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• v.49 no.4
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• pp.245-247
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• 2011

There were only a few reports of mercury on pulmonary artery. However, there is no data on surgery related mercury dissemination. The objective of the present article is to describe one case of postoperative injected mercury dissemination. A 19-year-old man presented severe neck pain including meningeal irritation sign and abdominal pain after injection of mercury for the purpose of suicide. Radiologic study showed injected mercury in the neck involving high cervical epidural space and subcutaneous layer of abdomen. Partial hemilaminectomy and open mercury evacuation of spinal canal was performed. For the removal of abdominal subcutaneous mercury, C-arm guided needle aspiration was done. After surgery, radiologic study showed disseminated mercury in the lung, heart, skull base and low spinal canal. Neck pain and abdominal pain were improved after surgery. During 1 month after surgery, there was no symptom of mercury intoxication except increased mercury concentration of urine, blood and hair. We assumed the bone work during surgery might have caused mercury dissemination. Therefore, we recommend minimal invasive surgical technique for removal of injected mercury. If open exposures are needed, cautious surgical technique to prohibit mercury dissemination is necessary and normal barrier should be protected to prevent the migration of mercury.

• The KIPS Transactions:PartD
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• v.8D no.4
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• pp.439-450
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• 2001

Mobile agent is one of the promising ways of overcoming network load and latency. It is also a new software paradigm including those concepts of client/server, applet/servelet, and code-on-demand. In this paper, a new mobile agent concept with flexible replay scheme is proposed, which can deal with embarrassing situation when replying results should be accomplished in various distributed applications. For example, they are 1) a burden of bulky result, 2) a need of different replay scheme dependent on work type, 3) connection failure to the target node, and 4) a need of fast migration to next node to keep the itinerary. Regarding the source node, there may be another situation that it wants to be aware of whether its wi가 is completed or not. Three kinds of reply schemes are proposed for dealing flexibly with such situations. They are based on priority reply list where nodes to be replied are stored according to their priorities. An experimental supply chain management model using the proposed reply schemes is designed and implemented. It is one of good distributed applications appropriate for our reply schemes, because it requires different reply schemes according to work types and it is important to gather required information in time.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.05a
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• pp.419-421
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• 2018

Cloud vehicular networks are a promising paradigm to improve vehicular through distributing computation tasks between remote clouds and local vehicular terminals. Software-Defined Network(SDN) can bring advantages to Intelligent Transportation System(ITS) through its ability to provide flexibility and programmability through a logically centralized controlled cluster that has a full comprehension of view of the network. However, as the SDN paradigm is currently studied in vehicular ad hoc networks(VANETs), adapting it to work on cloud-based vehicular network requires some changes to address particular computation features such as task computation of applications of cloud-based vehicular networks. There has been initial work on briging SDN concepts to vehicular networks to reduce the latency by using the fog computing technology, but most of these studies do not directly tackle the issue of task computation. This paper proposes a Software-Defined Cloud-based vehicular Network called SDCVN framework. In this framework, we study the effectiveness of task computation of applications of cloud-based vehicular networks with vehicular cloud and roadside edge cloud. Considering the edge cloud service migration due to the vehicle mobility, we present an efficient roadside cloud based controller entity scheme where the tasks are adaptively computed through vehicular cloud mode or roadside computing predictive trajectory decision mode. Simulation results show that our proposal demonstrates a stable and low route setup time in case of installing the forwarding rules of the routing applications because the source node needs to contact the controller once to setup the route.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.05a
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• pp.238-240
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• 2018

Cloud vehicular networks are a promising paradigm to improve vehicular through distributing computation tasks between remote clouds and local vehicular terminals. Software-Defined Network(SDN) can bring advantages to Intelligent Transportation System(ITS) through its ability to provide flexibility and programmability through a logically centralized controlled cluster that has a full comprehension of view of the network. However, as the SDN paradigm is currently studied in vehicular ad hoc networks(VANETs), adapting it to work on cloud-based vehicular network requires some changes to address particular computation features such as task computation of applications of cloud-based vehicular networks. There has been initial work on briging SDN concepts to vehicular networks to reduce the latency by using the fog computing technology, but most of these studies do not directly tackle the issue of task computation. This paper proposes a Software-Defined Cloud-based vehicular Network called SDCVN framework. In this framework, we study the effectiveness of task computation of applications of cloud-based vehicular networks with vehicular cloud and roadside edge cloud. Considering the edge cloud service migration due to the vehicle mobility, we present an efficient roadside cloud based controller entity scheme where the tasks are adaptively computed through vehicular cloud mode or roadside computing predictive trajectory decision mode. Simulation results show that our proposal demonstrates a stable and low route setup time in case of installing the forwarding rules of the routing applications because the source node needs to contact the controller once to setup the route.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.1
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• pp.21-29
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• 2023

The poor outcome of advanced ovarian cancer under conventional therapy necessitates new strategies to improve therapeutic efficacy. β-glucosidase (encoded by GBA) is a lysosomal enzyme and is involved in sphingolipids metabolism. Recent studies revealed that β-glucosidase plays a role in cancer development and chemoresistance. In this work, we systematically evaluated the expression and role of GBA in ovarian cancer. Our work demonstrates that inhibition of β-glucosidase has therapeutic potential for ovarian cancer. Gene Expression Profiling Interactive Analysis database, western blot and immunohistochemistry analyses of patient samples demonstrated that GBA mRNA and protein expression levels were significantly increased in ovarian cancer compared to normal tissues. Functional studies using gainof-function and loss-of-function approaches demonstrated that GBA overexpression did not affect growth and migration but alleviated cisplatin's efficacy in ovarian cancer cells. In addition, GBA depletion resulted in growth inhibition, apoptosis induction, and enhancement of cisplatin's efficacy. Of note, we found that GBA inhibition specifically decreased receptor tyrosine kinase AXL level, leading to the suppression of AXL-mediated signaling pathways. Our data suggest that GBA represents a promising target to inhibit AXL signaling and overcome cisplatin resistance in ovarian cancer.

• Nuclear Engineering and Technology
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• v.55 no.3
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• pp.958-967
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• 2023

This work studies the defect features in a dilute FeMnNi alloy by an Object Kinetic Monte Carlo (OKMC) model based on the "grey-alloy" method. The dose rate effect is studied at 573 K in a wide range of dose rates from 10^-8 to 10^-4 displacement per atom (dpa)/s and demonstrates that the density of defect clusters rises while the average size of defect clusters decreases with increasing dose rate. However, the dose-rate effect decreases with increasing irradiation dose. The model considered two realistic mechanisms for producing <100>-type self-interstitial atom (SIA) loops and gave reasonable production ratios compared with experimental results. Our simulation shows that the proportion of <100>-type SIA loops could change obviously with the dose rate, influencing hardening prediction for various dose rates irradiation. We also investigated ways to compensate for the dose rate effect. The simulation results verified that about a 100 K temperature shift at a high dose rate of 1×10^-4 dpa/s could produce similar irradiation microstructures to a lower dose rate of 1×10^-7 dpa/s irradiation, including matrix defects and deduced solute migration events. The work brings new insight into the OKMC modeling and the dose rate effect of the Fe-based alloys.

• Corrosion Science and Technology
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• v.23 no.2
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• pp.145-153
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• 2024

In the automotive industry, the hole expanding test is widely used to assess the formability of punched holes in sheets. This test provides a good representation of formability within the framework defined by the ISO 16630 standard. During hole expanding tests on galvanized high strength steels, a negative effect was observed when there was a delay between hole punching and expansion, as compared to performing both operations directly. This effect is believed to be caused by hydrogen aging, which occurs when hydrogen diffuses towards highly-work hardened edges. Therefore, the aim of this study is to demonstrate the migration of hydrogen towards work-hardened edges in high strength Zn-coated steel sheets using a novel Thermal Desorption Analyzer (TDA) designed for small samples. This newly-developed TDA setup allows for the quantification of local diffusible hydrogen near cut edges. With its induction heating and ability to analyze Zn-coated samples while reducing artifacts, this setup offers flexible heat cycles. Through this method, a hydrogen gradient is observed over short distances in shear-cut galvanized steel sheets after a certain period of time following punching.

• Journal of Korea Society of Digital Industry and Information Management
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• v.16 no.2
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• pp.35-43
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• 2020

Cloud computing integrates computing resources such as servers, storage, and networks with virtualization technology to provide suitable services according to user needs. Due to the structural characteristics of sharing physical resources based on virtualization technology, threats to availability can occur, so it is essential to respond to availability threats in cloud computing. Existing over-provisioning method is not suitable because it can generate idle resources and cause under-provisioning to degrade or disconnect service. System resources must be allocated in real-time according to the system load to guarantee the cloud system's availability. Through appropriate management measures, it is necessary to reduce the system load and increase the performance of the system. This paper analyzes the work response time according to the allocation or migration of virtual machines and discusses an efficient resource management method considering the system load.

• Journal of Korea Society of Industrial Information Systems
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• v.8 no.3
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• pp.99-104
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• 2003

Ad-hoc is the wireless network and consists of moving Hosts in environments which don't have a network-based Frame. Because ad-hoc is considered as broadcast network and network which has useful benefits, multicast muting protocols have been studied on ad-hoc network For this work we scrutinized ad-hoc and multicast routing protocols presented in previous works. And we presents a protocol for Ad-hoc network.

• Journal of Power System Engineering
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• v.4 no.3
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• pp.81-85
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• 2000

The surface gloss of the injection molded part is one of the most significant point for evaluation the quality of products appearance. The effects of molding condition on the gloss of HIPS(High Impact Poly Styrene) molded part were investigated in this work. The measurements of gloss on the surface of molded part were carried out with different melt temperature, mold temperature, injection pressure and holding pressure. We observed the result of HIPS gloss compared with our's previous ABS study. The more melt and mold temperature increased, the brighter the gloss increase. Holding and injection pressure had little effect on the gloss. The gloss was effected in order of melt temperature, mold temperature, injection pressure, holding pressure.