• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2009.11a
• /
• pp.87-91
• /
• 2009

Recycling demolished concrete as an alternative source of coarse aggregates for the production of new concrete can help solve the growing waste disposal crisis and the problem of depleted natural aggregates. The purpose of this study is to investigate chloride migration of recycled aggregate concrete containing pozzolanic materials by chloride migration coefficient. The specimens were made with recycled coarse aggregate as various replacement ratio(10, 30, 50%) and metakaolin, blast furnace slag, fly ash is replaced for recycled concrete with mixing ratio 20%. The major results are as follows. 1) Compressive strength of recycled aggregate concrete containing pozzolanic materials increase as curing age and chloride migration decrease. 2) When the replacement ratio of recycled coarse aggregate is 30%, the chloride migration coefficient of recycled concrete containing blast furnace slag, metakaolin shows the similar or lower value than plain concrete at all ages.

• Ocean Science Journal
• /
• v.42 no.1
• /
• pp.1-8
• /
• 2007

Acoustic volume backscattering strength data were collected and Conductivity Temperature Depth (CTD) measurements were conducted in the southern Yellow Sea in summer 2005 and 2006. The high temporal and vertical resolution acoustic data measured with a 307 kHz Acoustic Doppler Current Profiler (ADCP) and a 250 kHz acoustic Doppler profile (ADP) had dominant diel variation, which resulted from vertical migration of sound scatterers. Some scatterers congregating in the bottom layer in the daytime migrated upward at dusk, and migrated downward into the bottom layer at dawn. The migration speeds were estimated. More than 33 days data show that the diel migration varies with time. The feature of migration measured with ADCP and ADP is consistent to some extent with what is described in the study on vertical migration of zooplankton in the southern Yellow Sea with conventional net samples.

• Journal of Korean Society of Rural Planning
• /
• v.23 no.2
• /
• pp.43-54
• /
• 2017

When an age of low growth and population decline, population migration plays an important role in spatial structure of region. There have been many researches on migration and regional spatial structure. The purpose of this study is to examine the changes of Gwangju and Jeonnam region's spatial structure and central area using social network analysis methods. For analysis it was used that population and migration data and passenger OD(Origin and Destination) travel data released by Statistics Korea and Korea Transport Database(KTDB). Using Gephi 0.8.2, migration and passenger OD networks were visualized, and this describe network flow and density. The results of the network centrality analysis show that the most populated village is not always network center though population mass is an important factor of central places. The average eigenvector centrality of 2010 migration is the lowest during 2005-2015, and it means few regions have high centralities. When comparing migration and travel networks, travel data is more effective than migration data in determining the central location considering spatial functions.

• Journal of Agricultural Extension & Community Development
• /
• v.18 no.1
• /
• pp.1-33
• /
• 2011

In-migration has long been recognized as on important factor in rural development. Its impact can be expected to increase even further as the elderly population continues to grow. Recently with the retirement of baby boomers, postretirement moves have become increasingly important issue in rural Korea. Because the consequences of rural in-migration are often most pronounced at the local or regional level, rural planners are among the many scholars and practitioners seeking to understand the patterns and consequences of in-migration. At the same time, however, planners have sometimes overlooked basic research on the causes and determinants of mobility, and on the relationships between retirement migration and other socioeconomic processes. The papers aims to explore the reviews of rural in-migration studies and its practical implications, providing an interdisciplinary review of the most important studies published between 1990-2009. Through the literature review of in-migration, this study suggests that main arguments for rural in-imgration studies such as rural populations, counterurbanization, rural businesses incubator and rural amenity be emphasized to vitalize and diversify rural economies.

• Korean Journal of Environmental Biology
• /
• v.28 no.1
• /
• pp.8-13
• /
• 2010

This study aimed the role of gold nanoparticles (AuNP) in advanced glycation end-products (AGEs) induced migration and invasion in bovine retinal endothelial cells (BRECs). BRECs were isolated from the retina. Cell viability was confirmed by the MTT assay. In vitro wound migration assay was performed to investigate the migration of BRECs. In vitro tube formation was measured by on-gel system. Apoptosis induced by AuNP was confirmed by caspase-3 assay. AGE-bovine serum albumin (BSA) demonstrated increase of cell migration and proliferation in BRECs. In addition, AuNP regardless of the existence of AGE-BSA suppressed proliferation, migration, and angiogenesis. AuNP suppressed AGE-BSA induced migration and invasion, and induced apoptosis through caspase-3. As a results, AuNP have a potential anti-angiogenic effect for AGE-induced angiogenesis in vitro and offer possibility for the treatment of diabetic retinopathy.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2003.11a
• /
• pp.43-48
• /
• 2003

This paper investigate that the effect of the concrete containing mineral admixtures(pozzolanic materials such as fly-ash, ground granulated blast-furnace slag, silica fume and meta kaolin) on the resistance properties to chloride ion invasion. The purposed testing procedure was applied to the concrete added mineral admixtures for 3~4 replacement ratios under W/B ratios ranged from 0.40 to 0.55. For the electrical migration test, Tang and Nilsson's method was used to estimate the migration coefficient of chloride ion. As a results, the W/B ratios, kinds of admixture and replacement ratios, water curing periods had a great effect on the migration coefficient of chloride ion, and the optimal replacement ratios of admixture had a limitation for each admixtures. Also, the addition of mineral admixtures by mass(replacement of OPC) enhanced the resistance of the mixture to chloride penetration compared with the plain concrete. The amount of acid soluble chloride ions and water soluble chloride ions were varied with the kinds of mineral admixtures. The compressive strength was shown related to the migration coefficient of chloride ion, the compressive strength increased with the decreasing migration coefficient of chloride ion. Below the 50MPa, the variation of migration coefficient of concrete added mineral admixtures was bigger than plain concrete.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2003.05a
• /
• pp.43-48
• /
• 2003

This paper investigate that the effect of the concrete containing mineral admixtures(pozzaolanic materials such as fly-ash, ground granulated blast-furnace slag, silica fume and meta kaolin) on the resistance properties to chloride ion invasion. The purposed testing procedure was applied to the concrete added mineral admixtures for 3∼4 replacement ratios under W/B ratios ranged from 0.40 to 0.55. For the electrical migration test, Tang and Nilsson's method was used to estimate the migration coefficient of chloride ion. As a results, the W/B ratios, kinds of admixture and replacement ratios, water curing periods had a great effect on the migration coefficient of chloride ion, and the optimal replacement ratios of admixture had a limitation for each admixtures. Also, the addition of mineral admixtures by mass(replacement of OPC) enhanced the resistance of the mixture to chloride penetration compared with the plain concrete. The amount of acid soluble chloride ions and water soluble chloride ions were varied with the kinds of mineral admixtures. The compressive strength was shown related to the migration coefficient of chloride ion, the compressive strength increased with the decreasing migration coefficient of chloride ion. Below the 50MPa, the variation of migration coefficient of concrete added mineral admixtures was bigger than plain concrete.

• BMB Reports
• /
• v.53 no.12
• /
• pp.646-651
• /
• 2020

Bone resorption is linked to bone formation via temporal and spatial coupling within the remodeling cycle. Several lines of evidence point to the critical role of coupling factors derived from pre-osteoclasts (POCs) during the regulation of bone marrow-derived mesenchymal stem cells (BMMSCs). However, the role of glial cell-derived neurotrophic factor (GDNF) in BMMSCs is not completely understood. Herein, we demonstrate the role of POC-derived GDNF in regulating the migration and osteogenic differentiation of BMMSCs. RNA sequencing revealed GDNF upregulation in POCs compared with monocytes/macrophages. Specifically, BMMSC migration was inhibited by a neutralizing antibody against GDNF in pre-osteoclast-conditioned medium (POC-CM), whereas treatment with a recombinant GDNF enhanced migration and osteogenic differentiation. In addition, POC-CM derived from GDNF knock-downed bone marrow macrophages suppressed BMMSC migration and osteogenic differentiation. SPP86, a small molecule inhibitor, inhibits BMMSC migration and osteogenic differentiation by targeting the receptor tyrosine kinase RET, which is recruited by GDNF into the GFRα1 complex. Overall, this study highlights the role of POC-derived GDNF in BMMSC migration and osteogenic differentiation, suggesting that GDNF regulates bone metabolism.

• Biomolecules & Therapeutics
• /
• v.30 no.2
• /
• pp.170-178
• /
• 2022

The airway epithelium is equipped with the ability to resist respiratory disease development and airway damage, including the migration of airway epithelial cells and the activation of TLR3, which recognizes double-stranded (ds) RNA. Primary cilia on airway epithelial cells are involved in the cell cycle and cell differentiation and repair. In this study, we used Beas-2B human bronchial epithelial cells to investigate the effects of the TLR3 agonist polyinosinic:polycytidylic acid [Poly(I:C)] on airway cell migration and primary cilia (PC) formation. PC formation increased in cells incubated under serum deprivation. Migration was faster in Beas-2B cells pretreated with Poly(I:C) than in control cells, as judged by a wound healing assay, single-cell path tracking, and a Transwell migration assay. No changes in cell migration were observed when the cells were incubated in conditioned medium from Poly(I:C)-treated cells. PC formation was enhanced by Poly(I:C) treatment, but was reduced when the cells were exposed to the ciliogenesis inhibitor ciliobrevin A (CilioA). The inhibition of Beas-2B cell migration by CilioA was also assessed and a slight decrease in ciliogenesis was detected in SARS-CoV-2 spike protein (SP)-treated Beas-2B cells overexpressing ACE2 compared to control cells. Cell migration was decreased by SP but restored by Poly(I:C) treatment. Taken together, our results demonstrate that impaired migration by SP-treated cells can be attenuated by Poly(I:C) treatment, thus increasing airway cell migration through the regulation of ciliogenesis.

• Computers and Concrete
• /
• v.14 no.3
• /
• pp.263-277
• /
• 2014

This study investigated four electric field configurations of two-dimensional accelerate lithium migration technique (ALMT), including line-to-line, plane-to-line, contour-to-line and plane-to-plane, and analyzed the ion migration behavior and efficiency. It was found that the free ion distribution diagram and voltage distribution diagram were similar, and ions migrated in the power line direction. The electrode modules were used for the mortar specimen with w/c ratio of 0.5. The effectively processed areas accounted for 14.1%, 39.0%, 49.4% and 51.4% of total area respectively on Day 28. Larger electrode area was more advantageous to ion migration. In addition, it was proved that the two-dimensional electric field could be divided into different equifield line active regions, and regarded as affected by one-dimensional electric field, and the ion migration results in various equifield line active regions were predicted by using the duration analysis method based on the theoretical model of ion migration obtained from one-dimensional test.