• Toxicological Research
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• 제12권1호
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• pp.121-128
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• 1996

Group of 12 male and 12 female rabbits was given daily intravenous injections of different dosage of Ginkgo biloba extract(EGb 761), 7.5 mg/kg/day (low dosage group), 15 mg/kg/day (middle dosage group), or 30 mg/kg/day (high dosage group)for 3 month by ear vein according to Established Regulation of Korean National Institute of Safety Research (1994. 4. 14). Appearance, behavior, mortality, and food consumption of rabbits of treated groups were not affected during the experimental periods. No significant Ginkgo biloba extract(EGb 761)-related changes were found in urinalysis, hematology, serum chemistry, and organ weight. No histopathological lesions were seen in both control and treatment groups. Our results strongly suggest that no toxic changes should be found in rabbit treated intravenously with Ginkgo biloba extract(EGb 761)for 3 month.

• Journal of Korean Neurosurgical Society
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• 제60권1호
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• pp.118-124
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• 2017

Brain abscess commonly occurs secondary to an adjacent infection (mostly in the middle ear or paranasal sinuses) or due to hematogenous spread from a distant infection or trauma. Pulmonary arteriovenous fistulas (AVFs) are abnormal direct communications between the pulmonary artery and vein. We present two cases of brain abscess associated with asymptomatic pulmonary AVF. A 65-year-old woman was admitted with a headache and cognitive impairment that aggravated 10 days prior. An magnetic resonance (MR) imaging revealed a brain abscess with severe edema in the right frontal lobe. We performed a craniotomy and abscess removal. Bacteriological culture proved negative. Her chest computed tomography (CT) showed multiple AVFs. Therapeutic embolization of multiple pulmonary AVFs was performed and antibiotics were administered for 8 weeks. A 45-year-old woman presented with a 7-day history of progressive left hemiparesis. She had no remarkable past medical history or family history. On admission, blood examination showed a white blood cell count of 6290 cells/uL and a high sensitive C-reactive protein of 2.62 mg/L. CT and MR imaging with MR spectroscopy revealed an enhancing lesion involving the right motor and sensory cortex with marked perilesional edema that suggested a brain abscess. A chest CT revealed a pulmonary AVF in the right upper lung. The pulmonary AVF was obliterated with embolization. There needs to consider pulmonary AVF as an etiology of cerebral abscess when routine investigations fail to detect a source.

• 한국발생생물학회지:발생과생식
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• 제23권2호
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• pp.171-181
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• 2019

To produce healthy and stable seed production, we need to obtain information and understand vision that affects behavior of red spotted grouper. We examined their expression and retinal development during the juvenile development. Short-wavelength sensitive opsin (SWS2), a cone photoreceptor, began to be expressed from lens and ear vesicle formation stage and its expression increased until 10 days after hatching (dah). In case of middle-wavelength sensitive opsin (MWS), its expression was detected at 3 dah and reached the highest level at 21 dah. The expression of long-wavelength sensitive opsin (LWS) was first observed from 3 dah and their expression decreased thereafter. Rhodopsin, a rod photoreceptor, was found to be expressed from 2 dah and its expression reached the highest level at 50 dah. The outer nuclear layer (ONL), inner nuclear layer (INL) and ganglion cell layer began to differentiate at 2 dah, while choroid first appeared at 4 dah so that the eyes became black. These results indicate that the development of retina mostly completes around 4 dah. It seems that the development of the retina and the expression of the opsin genes are closely related to the behavior such as hunting prey, considering that the timing of the completion of the development of the retina, the timing of gene expression, and the timing of completion of yolk absorption are similar.

• 임상이비인후과
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• 제29권2호
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• pp.240-244
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• 2018

Granulomatosis with polyangiitis (GPA) and Immunoglobulin (Ig) $G_4$-related disease ($IgG_4$-RD) are rare diseases and early diagnosis and proper management are imperative to prevent multi-organ damage. The authors present a case of a 60 years old woman who had facial paralysis and hearing loss. Lt intact canal wall tympanomastoidectomy, Lt facial nerve decompression and ossiculoplasty with partial ossicular replacement prosthesis (PORP) was done. During operation, middle ear tissue was biopsied and GPA with $IgG_4$-RD was diagnosed. After methyl prednisolone (MPD) pulse therapy and azathioprine therapy, the severity of paralysis was improved. We present this case because common otologic symptoms like facial palsy and hearing loss could be initial symptoms of rare systemic disease.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• 제61권12호
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• pp.710-713
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• 2018

A congenital cholesteatoma is a benign mass formed from the keratinizing stratified squamous epithelium. It usually occurs in young children's anterosuperior part of the middle ear. A congenital cholesteatoma which originates from mastoid temporal bone or expands to posterior cranial fossa is rare. Standard treatment of an intracranial cholesteatoma is surgical removal with craniotomy. A 69-year-old woman was diagnosed with a congenital cholesteatoma of mastoid temporal bone that expanded to the posterior cranial fossa, which was successfully treated with transmastoid marsupialization without craniotomy. This is a first documented case of a congenital cholesteatoma of mastoid temporal bone that expanded to posterior cranial fossa, which was successfully treated with transmastoid marsupialization without craniotomy.

• 한국작물학회지
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• 제64권3호
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• pp.269-277
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• 2019

파종시기를 달리하여 옥수수 생육 및 수량성을 비교하고 출사기, 출사후 등숙기까지 적산온도를 활용하여 중북부지역에서 적합한 옥수수 파종시기를 구명하고자 2017~2018년 2년에 걸쳐 수행하였으며, 그 결과를 요약하면 다음과 같다. 1. 파종기가 빠를수록 토양온도가 낮아 옥수수 유묘 출현기간이 길었으며, 파종시 기별 평균 유묘 출현소요일수는 조생형인 미백2호가 9.1일, 중생형인 일미찰이 9.5일, 만생형인 찰옥4호가 10.1일 소요되어 조생형일수록 유묘출현소요일수가 짧았다. 2. 지온과 유묘 출현일수는 부의 상관관계를 나타내었는데, 지온이 낮은 4월에는 유묘 출현일수가 16~22일, 지온이 높은 5월에는 9~15일 정도로 감소하였다. 3. 파종기에 따른 경장, 이삭길이, 이삭폭은 수량과 정의 상관관계를 나타내었으며 조생형인 미백2호는 5월 15일, 중생형인 일미찰은 5월 25일, 만생형인 찰옥4호는 6월 15일 파종에서 각각 수량이 가장 높아 중북부지역의 평년기온 조건에서 생태형별 적정 파종기로 판단할 수가 있었다. 4. 동일 파종조건에서 출사 후 26일 까지 품종 간 유효적산 온도 차이는 적었으나 만생형 품종일수록 성숙기까지 소요적산온도가 적었는데 출사 후 26일까지 유효적산온도는 조생형인 미백2호가 $975^{\circ}C$, 만생형인 찰옥4호가 $604^{\circ}C$이었다. 5. 중북부지역에서 찰옥수수를 재배할 경우 생태형에 따른 품종의 파종지표로 유효적산온도를 활용할 경우 조생형인 미백2호는 출사 후 26일까지 적산온도, 중생형인 일미찰은 전 생육기간 적산온도, 만생형인 찰옥4호는 출사기까지 적산온도가 적합하였다. 6. 중북부지역(강원도, 경기북부)에서 생태형에 따른 찰옥수수를 재배 할 경우 파종기부터 등숙기까지 평균 적산온도는 약 $2,400^{\circ}C$, 평균 출사일수는 65일 이상 조건에서 10 a 당 1,200 kg 수준의 수량성 확보가 가능하였다.

• 한국치위생학회지
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• 제18권5호
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• pp.607-620
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• 2018

Objectives: The purpose of this study was to investigate the overall research trends and factors influencing dental fears in the last 10 years (2007-2017) and provide recommendations for future research. Methods: The literature review focused on dental fear research in Korea. Inclusion criteria of selected studies were as follows: studies that examined fear in middle school students or older, studies undertaken between 2007-2017, and studies that examined trends and factors relating to dental fears. Results: Findings from this literature review showed that the most commonly used tool for measuring dental fear was the Dental Fear Survey (DFS). A lack of trust towards the dentist increased dental fear among patients. Women managed fear better than men. Past pain experiences increased dental fear. The most frequent intervention for reducing fear was sound (41.7%). Most of the intervention studies demonstrated a reduction of fear, with the exception of interventions using ear plugs. Fear was increased in studies involving ear plugs. Conclusions: Based on the results of the study, specific measures should be taken to alleviate past pain experiences, such as the fear of anesthetic injections and sensations of the dental drill. Continuous research is needed to reduce dental fear.

• 디자인학연구
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• 제14권3호
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• pp.7-14
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• 2001

현대의 그래픽 디자인은 컴퓨터와 전자기술의 발달로 다양하고 첨단적인 이미지들의 스타일로 기존의 그래픽 디자인의 세계를 변화시키며 새로운 그래픽 디자인의 영역을 만들어가고 있다. 하지만 오늘날 그래픽 디자인 스타일의 기본 원리나 이미지들은 지난 20C초부터 중반까지 그래픽 디자인 사조들의 시각적 특징들이 반영된 각종 창작물들에 의해 다듬어지고 변화되어진 시각적 원리나 방법들의 영향을 받아 온 것이 사실이다. 일반적으로 모던 그래픽 디자인이라 부르고 있는 이 시기의 그래픽 디자인 스타일들은 20C 디자인의 시작이 되는 아르누보 이후 회화적 모더니즘, 구성주위, 신조형 주의, 바우하우스를 거치며 현대 그래픽 디자인의 기본적인 원리와 스타일을 형성하게 되는 스위스 그래픽 디자인 양식에서, 그리고 뉴욕파 그래픽 디자인에 이르러 전 세계로 퍼져가게 된다. 본 연구에서는 21C 급속한 그래픽 디자인의 표현 기술 발달과 다양한 그래픽 디자인 환경 속에서 현대 그래픽 디자인 원리의 바탕이 되는 20C 초반부터 중반까지 그래픽 디자인의 시각적 특징과 흐름의 조망을 통해 좀더 그래픽 디자인에 대한 체계적이고 근본적인 인식의 확보와 그래픽디자인의 시각적 특징을 이해하고 새로운 그래픽 스타일을 생산해 내는 하나의 연구 과정으로 삼고자 한다.

• 한국멀티미디어학회논문지
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• 제19권2호
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• pp.375-385
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• 2016

Recently, several implantable hearing aids such as cochlear implant, middle ear implant, etc., which have a module receiving power and signal from outside the body, are frequently used to treat the hearing impaired patients. Most of implantable hearing aids are adopted permanent magnet pairs to couple between internal and external devices for the enhancement of power transmission. Generally, the internal device which containing the magnet in the center of receiving coil is implanted under the skin of human temporal bone. In case of MRI scanning of a patient with the implantable hearing aid, however, homogeneous magnetic fields of the MRI might be interfered by the implanted magnet. For the above reasons, the MR image is degraded by large area of artifact, so that diagnostics are almost impossible in deteriorated region. In this paper, we proposed an external coil system that can reduce the artifact of MR image due to the internal coupling magnet. By finite element analysis estimating area of MR artifact according to varying current and shape of the external coil, optimal coil parameters were extracted. Finally, the effectiveness of the proposed external coil system was verified by confirming the artifact at real MRI scan.

• 한국환경농학회지
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• 제18권1호
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• pp.1-5
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• 1999

유기물 시용 및 벼 기상 생태형별 $CH_4$ 발생양상을 구명하고 이를 근거로 논 토양에서 배출되는 $CH_4$ 배출량을 추정하기 위해 미사질 양토에서 시험한 결과를 요약하면 다음과 같다. 1. 시기별 $CH_4$ 배출은 조생종이 2번의 peak를 나타냈으며 중생종과 만생종은 3번의 peak를 나타냈으며 줄기를 통한 $CH_4$ 배출은 온도가 높을수록 많은 경향이었다. 2. $CH_4$배출량은 조생종에 비하여 중생종과 만생종이 높은 경향이었으며, 볏짚 시용구와 비교해볼 때 볏짚 무시용구에서 46%의 $CH_4$ 배출이 감소되었다. 3. $CH_4$ 배출 계수($gm^{-2}day^{-1}$)는 조생종이 0.394, 중생종이 0.407, 만생종이 0.411이었으며, 볏짚 무시용시 $CH_4$ 배출계수는 조생종이 0.198, 중생종이 0.269, 만생종이 0.273이었다.