• Proceedings of the SCSK Conference
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• 2003.09a
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• pp.387-412
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• 2003

Influence of gelatinase on basement membrane (BM) structure was investigated by using a skin equivalent (SE) model. The results showed that (1) gelatinase produced by cells degraded the BM and (2) the addition of matrix metalloproteinase-specific inhibitor to the SE medium accelerated the formation of BM structure, indicating that gelatinase is involved in BM impairment. The activity of gelatinase was also studied in healthy human facial skin tissues. The result of in situ zymography revealed gelatinase activity around the basal layer of the epidermis, where BM integrity was severely compromised. Therefore, this enzyme was suggested to be associated with BM decomposition in human facial skin. To assess the behavior of gelatinase in stratum corneum (SC) non-invasively, an immunological study was performed. Since positive immunostaining of pro-gelatinase B was observed in SC stripped from sun-exposed skin, whereas no positive staining detected in SC of non-irradiated skin, gelatinase in the epidermis could be non-invasively detected by measuring gelatinase in SC. Gelatinase in SC of healthy female volunteers was monitored using a special film that sensitively and conveniently detects gelatinase. Ninetr percent of SC from facial skin (l00 women, 40's-50's) was gelatinase-positive. On the other hand, SC from non-irradiated skin was negative. These results strongly suggest that (1) gelatinase is constantly produced in the facial epidermis of most middle-aged woman during their daily life, and (2) the enzyme might be involved in the aging-related degeneration of both BM and the matrix fibers of the upper layer of the dermis, acting as a very important aging factor. Strong inhibitory activity against gelatinase was found in turmeric extract and identified curcumin as the major ingredient. Topical application of cream containing turmeric extract significantly decreased the number of gelatinase-positive SC clusters in human facial skins. These results indicated that turmeric is an effective ingredient to prevent skin from photo aging by suppressing chlonically upregulated gelatinase activity by UV and to improve skin condition.

• Journal of Fisheries and Marine Sciences Education
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• v.27 no.1
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• pp.160-169
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• 2015

The purpose of this study was to search and analyze the realities and needs of life long education, the necessity and perception of life competencies and the difference of competencies on experiences of education to support life long education system for adult learners in Busan and Ulsan. In this study, we conducted a questionnaire survey of 234 adult learners living in Busan and Ulsan. The results of this study were summarized as follows. First, adult learners perceived that life long education was very important to adults and appreciated an educational institution being managed by government. Second, adult learners thought that basic literacy competency and basic work competency were important and late fifties perceived that professional job is in important. Third, adult learners perceived that self directed learning and capacity of management are poor competencies. And they perceived that the government support adult learners who has economical difficulty. Forth, adult learners perceived that it was normal that 'professional job' and 'job transition abilities', 'women', 'the middle aged and old','the unemployed' and' low incomers' perceived that they have poor level. Fifth, according to the results of ${\chi}^2$ test for determining the statistical significance of differences in experience in lifelong learning among adult learner groups divided by their individual background, significant differences were observed in a few competencies(p<.05, p<.01).

• Journal of the Korea Convergence Society
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• v.11 no.11
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• pp.425-431
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• 2020

The purpose of this study was to examine validity of developed Logo-Autobiography for College students (LAC). The LAC was developed based on Frankl's logotherapy and Logo-Autobiography program for middle-aged women. Eleven college students participated in 6 sessions of LAC after 3 psychiatric nurse practitioners confirmed content validity of the program. Focus group interviews were conducted to identify participation experiences and to examine validity of the program sessions. Qualitative data were analyzed using content analysis method. A total of 9 themes were emerged from the data; 1)Realizing my existence, 2)Discovering my uniqueness of existence, 3)Thinking my future, 4)Experiences of encounter, 5)My uniqueness, 6)Experiences of successful coping, 7)Realizing freedom of attitude choice, 8)Needs of self-transcendence, and 9)Discovering my existence. The emerged 9 themes were all evaluated to be consistent with the objectives and topics of each session. We suggest a randomized experimental study to examine effects of LAC on college students' mental health.

• Journal of the Korean Home Economics Association
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• v.26 no.1
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• pp.21-31
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• 1988

The main problem of consumer behavior is choice since the outcome of me of a choice can only be known in the future, consumers are forced to deal with the risks of und\certainty. So, perception of risk is pivotal aspect of consumer behavior. This study was designed to investigate the relationships between purchasing behavior of textile and perceived risk. Data were obtained from 276 housewives. ANOVA, x2-test were employed to analyse the data. The result were : 1. general features of textile purchase behavior are as follows. Blend wools and pure wool products are prefered. Fall is the major season in purchasing textile. Wholesalers, department stores and agent stores are prefered. Purchasing decision making process independent upon not only textile itself but the practice value of the textile. Purchasing textile, married young women depend on outward shape of the textile, middle and old aged groups depend on the economic value of the textile and the credibility of the stores. 2. Perception of risk is relatively high in the preference of store, color/design, and psycological uncertainty. But the perceived risks is relatively low in brand, price and social credibility. 3. There is significant relationship between the recognition rate of risk and the sensitiveness of the consumer. In addition, there are strong relationship between the risk rate and the preference of shop, brand, and price. On the other hand, there are no significant relationship between the color, design, and sociopsyco-logical risk and demographic variables. 4. The perceived risk of consumer would be a key stone to grasp the consumer behavior. The product company needs to provide full information which could reduce the perceived risk of consumer. there attitude would help for the mutual interests. In the future research, we need to develop the precise methods for finding variables on the perceived risk during the process of making purchase intention.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2008.11a
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• pp.140-143
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• 2008

As the number of family living alone is expected to soar due to a change in socio-demographics like divorce, more middle-aged women returning to work, homes become smaller and so on. In addition to in 2020 these people will be increase so that 85 percent of the Koreans compose elderly living alone who is over 65. This study aims at developing a sharing-typed elderly people-centered rental model which is accessible in the community integration dimension as an alternative and finding out theirconscious, their need about residence. and we need to check about their major requirements on improvement step by step. so that we suggest the desirable way on the existing multi house. The model provides benefits in the social, economical and pragmatic dimensions as the families living alone get together and living with others, Particularly, as a residence model which reduces a psychological loneliness and at the same time enables the elderly to continue to live a life in the community while they live together with other people, this model could be a strategy which supports the "Aging in Place." This study is in progress via small group workshop which debate gradually about special subject with similar group member. So we can find the residence's preference on living environment in various condition and the member can imagine freely on their future living arrangement by giving the various informations which can be proceed in future. The workshop proceed three times. at the first workshop, we're check their living environment and satisfaction level. and second time we give the knowledge about shared-type rental house then discuss about the model. and last time we're listen to the residence's opinion.

• English Language & Literature Teaching
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• v.12 no.4
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• pp.235-251
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• 2006

This study aims to analyze what Saul Bellow wants to define "Love" in his recent work, More Die of Heartbreak. As a humanist, Saul Bellow is concerned about materialism in Post-modern age through his works. Today there are so many people that are hurt by the failure of love or experience heartbreak. We need to sense invisible danger all around us. We can find Bellovian love in More Die of Heartbreak. Bellow suggests that there should be "true love" between people, especially between men and women. But Kenneth Trachtenberg and Benn Crader have selfish and materialistic love. Kenneth had only a sensual desire for Treckie who is his daughter's mother. He cannot persuade Treckie to marry him. Benn, a middle-aged widower, peremptorily marries Matilda Layamon who is much younger than he. Unfortunately, the marriage brings him neither peace nor love. Benn recognizes his wrong conception of love through the death of Mrs. Bedell and Villitzer, and breaking off a marriage with Matilda. He decides to go to Antarctica. This is not an escape. This is his determination to save himself. At the North Pole he sets out to recover his gift of vision and redeem his fall from grace. He will desert his materialistic and absurd self. After the expedition, he will experience rebirth as an authentic human being who has acceptable eyes. Kenneth and Benn learn to conceive of love as one of man's strongest inner energies, for it is through love that you can penetrate to the essence of human being. In this study I try to define Bellovian love. In More Die of Heartbreak, love is a spiritual power that may even transfigure man.

• Journal of the Korean Society of Costume
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• v.50 no.4
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• pp.103-115
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• 2000

The purpose of this study is to provide consumers with practical information for reasonable purchasing by analyzing apparel purchasing behavior. information source use, demographic differences in terms of life style patterns, moreover, to support apparel manufacturers in producing goods and making a plan by developing more effective advertisements and efficient marketing strategy, such as media strategy. This study targeted 832 men and women wearing sports casual wear. Information source is used to analyze the data and MANOVA, ANOVA. Scheffe is employed for post-inspection and demographic bases are based on the frequency of each type. The followings are the conclusions of this study : 1. In case of print media, TV, PC factor, fashion advocates and individuality advocates most frequently used information source. In case of purchasing experience factor, individuality advocates skewed higher frequency than conformity type. and then, in case of observation information use factor, individuality advocates were ranked as the highest and conformity type as the lowest. In case of human information use factor, fashion advocates and individuality advocates showed higher frequency than practical type and conformity type. 2 In case of female, Individuality advocates was ranked as the highest. In case of male, practical type and conformity type were rank as the highest. Fashion advocates ranked as the lowest in any case. 3. Individuality advocates were ranked as the highest among people aged 14 to 16, practical type among 17 to 19, conformity type among 20 to 23, conformity type among over 20. 4. Middle school students tended to be the individuality advocates, high school students the practical type, university students the practical type and the conformity type, and company workers conformity type.

• Fashion & Textile Research Journal
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• v.13 no.6
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• pp.934-942
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• 2011

This study was intended to analyze conventional grading increments and methods for middle-age men's pants, and to suggest new grading guidelines that will enable to improve satisfaction with size and silhouette as a result of combining the concept of grading, which help maintain the ratio and proportion by sizes as one of ready-made apparel's advantages, with body form oriented and aesthetic approaches. In the apparel industry, the current sizing specifications and methods adopted by relevant companies, as well as the characteristics of body forms of men aged 35 to 55 years were comparatively analyzed to find out problems and ultimately to suggest their solutions or improvements. It was considered that as the conventional grading practices used in the industry were customary on the basis of the past experiences, it was required to take the body forms of target consumers into account and also, to reconsider the conventional grading methods. Analyses of sizing and specifications by brands show that 4 to 19 sizes including 82 or 84 as standard size have been produced. Since men's apparel has a large number of sizes with the large range of sizes, grading is critically important. As silhouettes depend on the distribution of grading rule values at each point of increment pattern in the main regions during grading, it is necessary to consider both size grading and form variations. To maintain an appropriate silhouette with keeping the angle of center back line of a pattern, it is desirable to set the ratio of side line part to center part from the crease line to approximately 3:7. It is required to diversify the values of grading rules according to different sizes and pattern regions in consideration for the body forms of key consumers. In addition, if the natural lines of designs and patterns for the width increments of waist circumference and hip circumference, the increments of hip width in pant's front and back panels, the ratio of grading rule values of the right and left sides of crease line, knee circumference, thigh circumference and so on are taken into account, grading will be satisfactory in the all aspects of size, silhouette and ratio.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6575-6579
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• 2015

Background: Breast cancer (BC) is the most frequent malignancy among females and is a leading cause of death of middle-aged women. Herein, we evaluated baseline characteristics for BC patients and also compared these variables across ealry and late recurrence groups. Materials and Methods: Between 1995 to 2014, among female breast cancer patients referred to our oncology clinic, eighty-six were entered into our study. All had distant metastasis. Early recurrence was defined as initial recurrence within 5 years following curative surgery irrespective of site. Likewise, late recurrence was defined as initial recurrence after 5 years. No recurrence was defined for survivors to a complete minimum of 10 years follow-up. Significant prognostic factors associated with early or late recurrence were selected according to the Akaike Information Criterion. Results: The median follow-up was 9 years (range, 1-18 years). During follow-up period, 51 recurrences occurred (distant metastasis), 31 early and 20 late. According to the site of recurrence, there were 51 distant. In this follow-up period, 19 patients died. Compared with the early recurrence group, the no recurrence group had lower lymph node involvement and more p53 positive lesions but the late recurrence group had lower tumor size. In comparison to no recurrence, p53 (odds ratio [OR] 6.94, 95% CI 1.49-32.16) was a significant prognostic factor for early recurrence within 5 years. Conclusions: Tumor size, p53 and LN metastasis are the most important risk factors for distance recurrence especially in early recurrence and also between of them, p53 is significant prognostic factor for early recurrence.

• Science of Emotion and Sensibility
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• v.16 no.1
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• pp.75-84
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• 2013

The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to yoga breathing ($pr{\bar{a}}n{\bar{a}}y{\bar{a}}ma$) have not been systematically explored yet. In this study, the effects of a yoga breathing program on prefrontal EEG were tested with middle-aged women. Participants were collected as volunteers and controlled into two groups. Two channel EEG was recorded in the prefrontal region (Fp1, Fp2) from the yoga breathing group (n=17) and control group (n=17). QEEG quotients were transformed from the EEGs and analyzed by the ANOVAs on gain scores. As a result, ${\alpha}/{\delta}$ (left, right) and CQ (correlation quotient) for yoga breathing participants were significantly decreased compared to control group (p<.05). ${\alpha}/{\beta}_H+{\alpha}/{\delta}$ (left, right) were increased significantly (p<.05). For those significantly changed QEEG quotients, the interaction effects of Group x prefrontal alpha (${\alpha}$) and beta (${\beta}$) asymmetry were tested. Only the ${\alpha}$ asymmetry showed main effect on the gain score of ${\alpha}/{\beta}_H+{\alpha}/{\delta}$ (right) with F (1, 34)＝5.694 (p<.05). Pearson's correlation coefficient between ${\alpha}$ asymmetry and gain score of ${\alpha}/{\beta}_H+{\alpha}/{\delta}$ (right) was .374 (p<.05). The gain score of ${\alpha}/{\beta}_H+{\alpha}/{\delta}$ (right) was increased for the right ${\alpha}$ dominance of yoga breathing group. On the contrary it was decreased for the left ${\alpha}$ dominance of yoga breathing group as well as the control regardless of the dominance. The result of this study implies that yoga breathing increases stress resistance and is effective in the management of physical stress. Emotionally relaxed people may have greater instantaneous stress reduction after yoga breathing. Moreover, yoga breathing could be also beneficial for depressed who may be more vulnerable to stress.