• Tuberculosis and Respiratory Diseases
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• v.70 no.3
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• pp.257-260
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• 2011

A 65-year-old woman was admitted due to poor oral intake and a dry cough over the previous 3 months. The physical examination was remarkable for bibasilar crackles, and plain chest radiography showed reticulation in both lower lung fields. A pulmonary function test demonstrated a restrictive pattern with a reduced diffusing capacity of the lung for carbon monoxide. High resolution computed tomography showed reticulation and honey-combing in both peripheral lung zones, which was consistent with usual interstitial pneumonia pattern. Her skin showed livedo reticularis. The erythrocyte sedimentation rate and C-reactive protein level were elevated, and hematuria was noted on urinary analysis. A serologic test for auto-antibodies showed seropositivity for Myeloperoxidase-Anti-neutrophil cytoplasmic antibody (MPO-ANCA). A kidney biopsy was performed and showed focal segmental glomerulosclerosis. She was diagnosed as having pulmonary fibrosis with microscopic polyangiitis (MPA) and treated with high dose steroids. Here we report a case of pulmonary fibrosis coexistent with microscopic polyangiitis.

• Journal of Korean Neurosurgical Society
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• v.54 no.4
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• pp.317-322
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• 2013

Objective : The surgical approach for recurrent pituitary adenoma after trans-sphenoidal approach (TSA) is challenging. We report the outcomes of the endoscopic TSA for recurrent pituitary adenoma after microscopic TSA. Methods : From February 2010 to February 2013, endoscopic TSA was performed for removal of 30 recurrent pituitary adenomas after microscopic TSA. Twenty-seven (90%) patients had a clinically non-functioning pituitary adenoma. Twenty-four (80%) patients suffered from a visual disturbance related to tumor growth. The clinical features and surgical outcomes were retrospectively analyzed for the ophthalmological, endocrinological, and oncological aspects. Results : The mean tumor volume was 11.7 $cm^3$, and gross total resection was achieved in 50% of patients. The volumetric analysis based on the postoperative MR showed that the mean extent of resection rates were 90%. Vision was improved in 19 (79%) of 24 patients with visual symptoms, and endocrinological cure was achieved in all of three functioning pituitary adenomas; however, the post-operative follow-up endocrinological examination revealed a new endocrinological deficit in one patient. Two patients required antibiotics management for post-operative meningitis. Conclusion : The endoscopic TSA can be an effective treatment option for recurrent pituitary adenoma after microscopic TSA with acceptable outcome.

• Korean Journal of Optics and Photonics
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• v.17 no.2
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• pp.149-158
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• 2006

We have analyzed various tolerances of the multi-configurative microscopic system for inspecting the wire-bonding of a reed frame by using the Gaussian bracket method and the equivalent lens method. The tolerances for the curvature and the thickness, which are axial symmetric tolerances, are given by varying the back focal length within a fecal depth under diffraction-limited conditions. Moreover, by using the trial and error method, the axial non-symmetric tolerances for decenter and tilt are established by assigning the 5% variation of MTF(modulation transfer function) at the spatial frequency of 50 lp/mm and at the field angle of 0.7 field. As the tolerances with the most probable distribution are distributed within the range of the decay rate of less than 5% independent of the probability distribution of tolerances, we can achieve completely the desired design performances of the multi-configurative microscopic system by using the various ranges of these tolerances.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.1
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• pp.384-390
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• 2019

The importance of architecture design focused on eco-friendly and low energy continues to grow. In addition, the energy conservation design is required from a micro-perspective. Energy simulations based on BIM have attracted recent attention because of the high efficiency. On the other hand, the parameters concerned with microscopic energy are not included in BIM data. This study examined the necessity of the sensor-light parameter using a simulation of illuminance sensor light. In this study, illuminance sensors were installed into the BIM data and the operating schedule data of sensor light were generated by an illuminance simulation. The schedule data was then inputted into the simulation application, and the reduction ratio of power consumption was verified by the simulation. According to research, the power consumption and thermal load decreased by more than 20 %. Therefore, it is necessary to supplement the sensor-light parameter into BIM data for microscopic energy conservation design. This study was not confined to checking whether sensor-light parameter is necessary or not, but to ascertaining the necessary of applying a microscopic factor to generate BIM data.

• Journal of Korean Dental Science
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• v.5 no.2
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• pp.77-87
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• 2012

Purpose: This study examined the scanning electron microscopic feature, protein marker expression and osteoinductive activity of demineralized dentin matrix (DDM) from human for nude mice. Materials and Methods: Twenty healthy nude mice, weighing about 20 g were used for study. DDM from Human was prepared and implanted into the dorsal portion of nude mouse. Before implantation, DDM was examined by scanning electron microscopy (SEM). Nude mice were sacrificed at 2 weeks, 4 weeks and 8 weeks after DDM grafting and evaluated histologically by H-E, MT staining. And also immunohistochemistry analysis (ostecalcin, osteopontin) was performed. Result: Dentinal tubules and collagen fibers were observed by SEM of dentin surface of DDM. The DDM induced bone and cartilage independently in soft tissues. And, the histological findings showed bone forming cells like osteoblasts, fibroblasts at 2, 4 and 8 weeks. On immunohistochemistry analysis, osteocalcin and osteopontin positive bone forming cells were observed. Conclusion: This results showed that the DDM from human has osteoinductive ability and is a good alternative to autogenous bone graft materials.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.20 no.3
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• pp.353-364
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• 2007

In this paper, a nonlinear finite element analysis program NUCAS, which has been developed for assessment of ultimate pressure capacity and failure mode for nuclear containment building is described. Degenerated shell element with assumed strain method and low-order solid element with enhanced assumed strain method is adapted to microscopic material and elasto-plastic material model, respectively. Finally, the performance of the developed program is tested and demonstrated with several examples. From the numerical tests, the present results show a good agreement with experimental data or other numerical results.

• International Journal of Highway Engineering
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• v.14 no.6
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• pp.183-190
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• 2012

PURPOSES : The fundamental diagram provides basic information necessary in the analysis of traffic flow and highway operation. When traffic flow is congested, the density-flow points in the fundamental diagram are widely scattered and move in a stochastic manner. This paper investigates the pattern of density-flow point transitions and identifies car-following behaviors underlying the density-flow transitions. METHODS : From a microscopic analysis of 722 fundamental diagrams of NGSIM data, a total of 20 transition patterns of fundamental diagrams are identified. Prominent features of the transition patterns are explained by the behavior of the leader and follower. RESULTS : It is found out that the average speed and the speed difference between the leader and the follower critically determine the density-flow transition pattern. The density-flow path is very sensitive to the values of vehicle speed and spacing especially at low speed and high density such that most fluctuations in the fundamental diagram in the congested regime is due to the noise of speed and spacing variations. CONCLUSIONS : The result of this study suggests that the average speed, the speed difference between the leader and the follower, and the random variations of speed and spacing are dominant factors that explain the transition patterns of a fundamental diagram.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2004.04a
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• pp.67-70
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• 2004

An investigation was performed to study the impact damage of the laminated composite plates caused by a low- velocity foreign object with multi-scale modeling based on the concepts of Direct Numerical Simulation (DNS)[4]. In the micro-scale part, we discretize the composite plates through separate modeling of fiber and matrix for the local microscopic analysis. A micro-scalemodel was developed for predicting the initiation of the damage and the extent of the final damage as a function of material properties, laminate configuration and the impactor's mass, etc. Anda macro-scale model was developed for description of global dynamic behavior. The connection betweenmicroscopic and macroscopic is implemented by the tied interface constraints of LS-DYNA contact card. A transient dynamic finite element analysis was adopted for calculating the contact force history and the stresses and strains inside the composites during impact resulting from a point-nose impactor. The low-velocity impact events such as contact force, deformation, etc. are simulated in the macroscopic sense and the impact damages, fiber-breakage, matrix cracking and delamination etc. are examined in the microscopic sense.

• Bulletin of the Korean Chemical Society
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• v.30 no.1
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• pp.183-187
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• 2009

The structure of nano-crystalline $MnFe_2O_4$ was determined and refined with electron powder diffraction data employing the Rietveld refinement technique. A nano-crystalline sample (with average crystal size of about 10.9 nm) was characterized by selected area electron diffraction in an energy-filtering transmission electron microscope operated at 120 kV. All reflection intensities were extracted from a digitized image plate using the program ELD and then used in the course of structure refinements employing the program FULLPROF for the Rietveld analysis. The final structure was refined in space group Fd-3m (# 227) with lattice parameters a=8.3413(7) $\AA$. The reliability factors of the refinement are $R_F$=7.98% and $R_B$=3.55%. Comparison of crystallographic data between electron powder diffraction data and reference data resulted in better agreement with ICSD-56121 rather than with ICSD-28517 which assumes an initial structure model.

• Journal of Navigation and Port Research
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• v.31 no.1 s.117
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• pp.107-113
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• 2007

This research addressed the problem of describing how the operating characteristics of passenger car and large vehicle differ qualitatively and quantitatively through the analysis of field survey data. A formulation that estimates passenger car equivalents used in this paper is derived by microscopic headway method. Regression analysis was used to focus on the effect of vehicle type on intervehicular spacings and the modeling technique for the statistical analysis was detailed.