• Title/Summary/Keyword: micro-total-analysis-system

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Development of A New Device for Controlling Infinitesimal Flows inside a Lab-On-A-Chip and Its Practical Application (랩온어칩 내부 미세유동 제어를 위한 새로운 장치의 개발 및 적용)

  • Kim, Bo-Ram;Kim, Guk-Bae;Lee, Sang-Joon
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.305-308
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    • 2006
  • For controlling micro-flows inside a LOC (lab-on-a-chip) a syringe pump or an electronic device for EOF(electro-osmotic flow) have been used in general. However, these devices are so large and heavy that they are burdensome in the development of a portable micro-TAS (total analysis system). In this study, a new flow control system employing pressure chambers, digital switches and speed controllers was developed. This system could effectively control the micro-scale flows inside a LOC without any mechanical actuators or electronic devices We also checked the feasibility of this new control system by applying it to a LOC of micro-mixer type. Performance tests show that the developed control system has very good performance. Because the flow rate in LOC is controlled easily by throttling the speed controller, the flows in complicate microchannels network can be also controlled precisely.

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Power Conditioning for a Small-Scale PV System with Charge-Balancing Integrated Micro-Inverter

  • Manoharan, Mohana Sundar;Ahmed, Ashraf;Seo, Jung-Won;Park, Joung-Hu
    • Journal of Power Electronics
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    • v.15 no.5
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    • pp.1318-1328
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    • 2015
  • The photovoltaic (PV) power conditioning system for small-scale applications has gained significant interest in the past few decades. However, the standalone mode of operation has been rarely approached. This paper presents a two-stage multi-level micro-inverter topology that considers the different operation modes. A multi-output flyback converter provides both the DC-Link voltage balancing for the multi-level inverter side and maximum power point tracking control in grid connection mode in the PV stage. A modified H-bridge multi-level inverter topology is included for the AC output stage. The multi-level inverter lowers the total harmonic distortion and overall ratings of the power semiconductor switches. The proposed micro-inverter topology can help to decrease the size and cost of the PV system. Transient analysis and controller design of this micro-inverter have been proposed for stand-alone and grid-connected modes. Finally, the system performance was verified using a 120 W hardware prototype.

Analysis of the Relation Between Micro-Speaker with the Back Holes and the Ducted Speaker-System (후면기공을 갖는 마이크로스피커와 덕트형 스피커시스템사이의 연관성 해석)

  • Rhee, Esther;Oh, Sei-Jin
    • The Journal of the Acoustical Society of Korea
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    • v.26 no.3
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    • pp.115-122
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    • 2007
  • In this study, the property and the structure of micro-speaker had been firstly shown to be treated as a ducted speaker-system, which was consisted of the unit and the ducted enclosure. With the decrease of total hole area. the resonance frequency of micro-speaker was decreased due to increasing the stiffness or reducing the compliance. The behavior of resonance frequency relative to the total hole area was exactly agreed with that of the square root of compliance. With decreasing the total hole area. the effective chamber volume was increased, but the reference sound pressure level was exponentially reduced in the low and middle frequency range.

Analysis of Micro Injection Molding Process for Polymeric Microneedle Fabrication (플라스틱 마이크로니들의 미세사출성형공정에 대한해석)

  • Lee S. H.;Kang J. J.;Heo Y. M.;Jung T. S.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2005.05a
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    • pp.55-59
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    • 2005
  • Micro injection molding analysis for microneedle fabrication was performed in the present study. The dimensions of width and thickness for microneedle are 600um, 500um, respectively. A delivery system based on guidelines for traditional injection molding was designed for four-cavities molding system. To investigate the effects of processing conditions in the mirconeedle fabrication, injection molding analysis using commercial code was performed. It was shown that the total injection time has a significant effect on the fabrication of microneedles.

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Structural Analysis and Optimum Design of a De-coupled Vertical Micro-Gyroscope (비연성 수직형 마이크로 자이로스코프의 구조해석 및 최적설계)

  • Park, Sung-Kyoon;Jeong, Hee-Moon;Kim, Myung-Hoon;Kim, Hyung-Tae;Ha, Sung-Kyu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.27 no.11
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    • pp.1840-1848
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    • 2003
  • This paper presents the structural analysis and optimum design of a vertical micro-gyroscope with decoupled 2 degrees of freedom (DOF), driven by electrostatic force. Simplified beam models were presented to derive the structural stiffness of the driving spring of the U shape and the sensing spring of I shape. A finite element analysis (FEA) was performed to validate each derivation. A total mass and a polar mass moment of inertia were also obtained and used in calculating the resonance frequency at each mode of the 2 DOF. The resonance frequencies of the total system were calculated using the proposed models and it has been found that they were in excellent agreement with those of the FEA. Finally, the developed analysis program was then linked to an optimum design module, and an optimum design of the micro-gyroscope was successfully performed.

A Study on Process Simulation Analysis of the Water Jet Cleaning Robot System for Micro Drill-bits (마이크로 드릴비트의 워터젯 세척 로봇시스템의 공정 시뮬레이션 분석에 관한 연구)

  • Kuk, Youn-Ho;Park, Sang-Rok;Park, Kee-Jin;Choi, Hyun-Jin
    • Korean Journal of Computational Design and Engineering
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    • v.20 no.3
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    • pp.291-297
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    • 2015
  • A water jet cleaning robot system for micro drill bits is to refurbish micro drill bits used for the PCB manufacturing process. It can refurbish drill bits with the minimum diameter of ${\phi}0.15{\sim}0.075mm$ of which the total quantity have been discarded before. Micro drill bits with the minimum diameter of ${\phi}0.075mm$ can be cleaned by applying the water jet cleaning robot system out of the manual ultrasonic cleaning in the past for the cleaning equipment as the initial process in refurbishing. This study analyzed problems, while applying the apparatus mechanism for the workability such as the robot traces of Transfer Robot I and II, drill bit loading and unloading, and cleaning tasks in the water jet cleaning robot system in an effort to carry out simulations. In addition, the cleaning work process was optimized as the work process was verified in advance and the production quantity was analyzed through simulations.

A proposal of new electronics device;micro-total analysis system for capillary electrophoresis

  • Oshige, Seisho;Aoyama, T.;Kambe, J.;Nagashima, U.
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.579-581
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    • 2004
  • We wish to develop micro-total analysis system (TAS) on a chip, and to make a trial approach to solve the important problem that is to detect ions separated by the electric field. We propose an idea, which is as for rotational motions of dipolar ions, which are affected by the ion atmosphere in outer regions. This is a new kind of the ion-sensitive field effect transistor (ISFET). We wish to develop the ISFET chips, and give more effective, fast and sensitive, capillary electrophoresis is designed in near future.

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[ μ ]-Injection Molding Process Analysis for In-Plane Microneedle (In-Plane형 마이크로니들의 미세사출공정해석)

  • Kang J. J.;Heo Y. M.;Jung T. S.;Lee S. H.
    • Transactions of Materials Processing
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    • v.14 no.6 s.78
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    • pp.491-495
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    • 2005
  • Micro injection molding analysis for microneedle fabrication was performed in the present study. The dimensions of width and thickness for in-plane microneedle are $600{\mu}m$, $500{\mu}m$, respectively. A delivery system based on guidelines for traditional injection molding was designed for four-cavities molding system. To investigate the effects of processing conditions in the mirconeedle fabrication, injection molding analysis using commercial code was performed. It was shown that the total injection time has a significant effect on the fabrication of in-plane microneedles.

Miniaturized Fluorometer Based on Total Internal Reflector and Condensing Mirror

  • Jang, Dae-Ho;Yoo, Jae-Chern
    • Journal of the Optical Society of Korea
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    • v.17 no.1
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    • pp.81-85
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    • 2013
  • A miniaturized fluorescence detection system based on total internal reflection (TIR) configuration, which is applicable to detecting the presence of biological materials labeled with fluorescence dye in micro total analysis systems (${\mu}TAS$), is proposed. In conventional fluorescence testing and analysis devices, interference between the excitation light beam and the emitted light from dyes is unavoidable. This paper presents a fluorescence detection system based on TIR configuration that allows the excitation light beam and the emitted light to be spatially perpendicular to each other so as to minimize the interference where fluorescence emission is detected at the orthogonal angle to the excitation beam. We achieved the limit of detection of about 5 nmol/L with a high linearity of 0.994 over a wide range of 6-FAM mol concentration, being comparable to that in earlier studies.

BEAD BASED CHEMICAL REACTION SYSTEM USING TEMPERATURE AND FLUID CONTROL FOR CANCER DETECTION (유체와 온도 조절을 이용한 생화학 물질 반응용 마이크로칩의 개발)

  • Kim, Min-Su;Lee, Bo-Rahm;Yoon, Hyo-Jin;Kim, Byung-Gee;Lee, Yoon-Sik;Kim, Yong-Kweon
    • Proceedings of the KIEE Conference
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    • 2008.07a
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    • pp.1466-1467
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    • 2008
  • We describe here a novel micro total analysis system for the purification and identification of the affinity-captured proteins. Also we demonstrated the mass analysis of the Carcinoembrionic antigen (CEA) and Alpha femtoprotein which were chosen as the target cancer marker. For MALDI-TOF analyses, the proteins should to be separated from a protein mixture and be concentrated when needed. This procedure usually takes a long time even before protease-digested samples are to be obtained from them. Here, we describe integrated and efficient micro chip for protein purification and digestion for MALDI-TOF analyses. At first, disease protein is purified by passing the micro chamber from a protein mixture or human whole serum and released from the micro affinity beads by thermal heating. Purified protein is then transfer to the hole for trypsin digestion. The final sample is analyzed by MALDI-TOF. All the processes could be finished successfully within one hour, which renders MALDI-TOF analyses of a target protein quite simple.

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