• 제목/요약/키워드: micro-CT

검색결과 421건 처리시간 0.031초

흰쥐 미세구조 관찰을 위한 Micro-CT 3D 영상의 유용성에 관한 연구 (A Study on the Usefulness of 3D Imaging in Micro-CT for Observing the Microstructure of Mice)

  • 이상호;이종석;임청환;정홍량;채규윤;한범휘;한상현;홍동희;한태종;박성훈;모은희;전홍영
    • 디지털융복합연구
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    • 제12권3호
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    • pp.367-375
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    • 2014
  • 본 연구는 실시간 동적영상(Real-time dynamic image)을 획득할 수 있는 고해상도 엑스선 영상장치인 마이크로 CT 을 이용하여 흰쥐의 미세 혈관구조를 관찰함은 물론 국내 원광 방사선영상 과학연구 센터에서 개발한 마이크로 CT 에 대한 유용성을 알아보고자 한다. 흰쥐 몸 전체의 2D 영상을 얻은 후 MIP(maximum intensity projection), VRT(volume rendering technique)기법을 이용하여 혈관구조의 조영된 3D 영상을 얻을 수 있었고 이 3D 혈관 영상을 머리, 복부, 심장과 몸 전체의 혈관시스템으로 각각 분류하였다.

대퇴골 전자간부 해면골의 미세구조적 특성과 생역학적 특성에 관한 연구 (A study on the micro-structural and biomechanical properties of trabecular bone in intertrochanteric region)

  • 백명현;원예연;최문권;김광균;김한성
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2005년도 춘계학술대회 논문집
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    • pp.923-926
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    • 2005
  • To investigate the relationship between BMD, micro-structural and mechanical properties in intertrochanteric trabecular bone, the PIXI-mus2 system, micro-CT and FE model were used. The purpose of this study were (1) to apply high-resolution imaging techniques (micro-CT imaging) in combination with new computer modeling techniques (FEA) to quantify 3D microstructural and biomechanical properties of trabecular bone in the intertrochanteric region, and (2) determine if the prediction of bone elastic constant can be improved with structural index.

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3D micro-CT analysis of void formations and push-out bonding strength of resin cements used for fiber post cementation

  • Uzun, Ismail Hakki;Malkoc, Meral Arslan;Keles, Ali;Ogreten, Ayse Tuba
    • The Journal of Advanced Prosthodontics
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    • 제8권2호
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    • pp.101-109
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    • 2016
  • PURPOSE. To investigate the void parameters within the resin cements used for fiber post cementation by micro-CT (${\mu}CT$) and regional push-out bonding strength. MATERIALS AND METHODS. Twenty-one, single and round shaped roots were enlarged with a low-speed drill following by endodontic treatment. The roots were divided into three groups (n=7) and fiber posts were cemented with Maxcem Elite, Multilink N and Superbond C&B resin cements. Specimens were scanned using ${\mu}CT$ scanner at resolution of $13.7{\mu}m$. The number, area, and volume of voids between dentin and post were evaluated. A method of analysis based on the post segmentation was used, and coronal, middle and apical thirds considered separately. After the ${\mu}CT$ analysis, roots were embedded in epoxy resin and sectioned into 2 mm thick slices (63 sections in total). Push-out testing was performed with universal testing device at 0.5 mm/min cross-head speed. Data were analyzed with Kruskal-Wallis and Mann-Whitney U tests (${\alpha}=.05$). RESULTS. Overall, significant differences between the resin cements and the post level were observed in the void number, area, and volume (P<.05). Super-Bond C&B showed the most void formation ($44.86{\pm}22.71$). Multilink N showed the least void surface ($3.51{\pm}2.24mm^2$) and volume ($0.01{\pm}0.01mm^3$). Regional push-out bond strength of the cements was not different (P>.05). CONCLUSION. ${\mu}CT$ proved to be a powerful non-destructive 3D analysis tool for visualizing the void parameters. Multilink N had the lowest void parameters. When efficiency of all cements was evaluated, direct relationship between the post region and push-out bonding strength was not observed.

Spiral scanning imaging and quantitative calculation of the 3-dimensional screw-shaped bone-implant interface on micro-computed tomography

  • Choi, Jung-Yoo Chesaria;Choi, Cham Albert;Yeo, In-Sung Luke
    • Journal of Periodontal and Implant Science
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    • 제48권4호
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    • pp.202-212
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    • 2018
  • Purpose: Bone-to-implant contact (BIC) is difficult to measure on micro-computed tomography (CT) because of artifacts that hinder accurate differentiation of the bone and implant. This study presents an advanced algorithm for measuring BIC in micro-CT acquisitions using a spiral scanning technique, with improved differentiation of bone and implant materials. Methods: Five sandblasted, large-grit, acid-etched implants were used. Three implants were subjected to surface analysis, and 2 were inserted into a New Zealand white rabbit, with each tibia receiving 1 implant. The rabbit was sacrificed after 28 days. The en bloc specimens were subjected to spiral (SkyScan 1275, Bruker) and round (SkyScan 1172, SkyScan 1275) micro-CT scanning to evaluate differences in the images resulting from the different scanning techniques. The partial volume effect (PVE) was optimized as much as possible. BIC was measured with both round and spiral scanning on the SkyScan 1275, and the results were compared. Results: Compared with the round micro-CT scanning, the spiral scanning showed much clearer images. In addition, the PVE was optimized, which allowed accurate BIC measurements to be made. Round scanning on the SkyScan 1275 resulted in higher BIC measurements than spiral scanning on the same machine; however, the higher measurements on round scanning were confirmed to be false, and were found to be the result of artifacts in the void, rather than bone. Conclusions: The results of this study indicate that spiral scanning can reduce metal artifacts, thereby allowing clear differentiation of bone and implant. Moreover, the PVE, which is a factor that inevitably hinders accurate BIC measurements, was optimized through an advanced algorithm.

Evaluation of reparative dentin formation of ProRoot MTA, Biodentine and BioAggregate using micro-CT and immunohistochemistry

  • Kim, Jia;Song, Young-Sang;Min, Kyung-San;Kim, Sun-Hun;Koh, Jeong-Tae;Lee, Bin-Na;Chang, Hoon-Sang;Hwang, In-Nam;Oh, Won-Mann;Hwang, Yun-Chan
    • Restorative Dentistry and Endodontics
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    • 제41권1호
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    • pp.29-36
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    • 2016
  • Objectives: The purpose of this study was to assess the ability of two new calcium silicate-based pulp-capping materials (Biodentine and BioAggregate) to induce healing in a rat pulp injury model and to compare them with mineral trioxide aggregate (MTA). Materials and Methods: Eighteen rats were anesthetized, cavities were prepared and the pulp was capped with either of ProRoot MTA, Biodentine, or BioAggregate. The specimens were scanned using a high-resolution micro-computed tomography (micro-CT) system and were prepared and evaluated histologically and immunohistochemically using dentin sialoprotein (DSP). Results: On micro-CT analysis, the ProRoot MTA and Biodentine groups showed significantly thicker hard tissue formation (p < 0.05). On H&E staining, ProRoot MTA showed complete dentin bridge formation with normal pulpal histology. In the Biodentine and BioAggregate groups, a thick, homogeneous hard tissue barrier was observed. The ProRoot MTA specimens showed strong immunopositive reaction for DSP. Conclusions: Our results suggest that calcium silicate-based pulp-capping materials induce favorable effects on reparative processes during vital pulp therapy and that both Biodentine and BioAggregate could be considered as alternatives to ProRoot MTA.

Comparison of micro-computerized tomography and cone-beam computerized tomography in the detection of accessory canals in primary molars

  • Acar, Buket;Kamburoglu, Kivanc;Tatar, Ilkan;Arikan, Volkan;Celik, Hakan Hamdi;Yuksel, Selcen;Ozen, Tuncer
    • Imaging Science in Dentistry
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    • 제45권4호
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    • pp.205-211
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    • 2015
  • Purpose: This study was performed to compare the accuracy of micro-computed tomography (CT) and cone-beam computed tomography (CBCT) in detecting accessory canals in primary molars. Materials and Methods: Forty-one extracted human primary first and second molars were embedded in wax blocks and scanned using micro-CT and CBCT. After the images were taken, the samples were processed using a clearing technique and examined under a stereomicroscope in order to establish the gold standard for this study. The specimens were classified into three groups: maxillary molars, mandibular molars with three canals, and mandibular molars with four canals. Differences between the gold standard and the observations made using the imaging methods were calculated using Spearman's rho correlation coefficient test. Results: The presence of accessory canals in micro-CT images of maxillary and mandibular root canals showed a statistically significant correlation with the stereomicroscopic images used as a gold standard. No statistically significant correlation was found between the CBCT findings and the stereomicroscopic images. Conclusion: Although micro-CT is not suitable for clinical use, it provides more detailed information about minor anatomical structures. However, CBCT is convenient for clinical use but may not be capable of adequately analyzing the internal anatomy of primary teeth.

Molar-incisor malformation에 이환된 제2유구치의 미세 형태학적 분석 : 증례 보고 (Micromorphological Analysis of Primary Second Molar with Molar-incisor Malformation : A Case Report)

  • 김명환;박호원;이주현;서현우
    • 대한소아치과학회지
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    • 제48권3호
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    • pp.352-358
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    • 2021
  • Molar-incisor malformation (MIM)은 치관은 정상이나 치근의 비정상적인 형태를 보이는 것이 특징적이다. 제1대구치에 가장 많이 발생하며, 제2유구치나 상악 중절치도 때때로 이환된다. 이 증례 보고에서는 제1대구치를 포함해, 제2유구치에 MIM이 나타난 환자의 증례를 보고하고, 치근이 건전하게 발거된 제2유구치의 micro computed tomography (CT)를 이용한 형태학적 분석을 시행하였다. 발거된 치아에서는 MIM의 외형적 특징인 치관 - 치근 이행부의 cervical constriction을 육안상으로 확인할 수 있었으며, micro CT 분석에서 백악법랑경계부의 광화된 부위 (Cervical Minelarized Diaphragm), 많은 부근관과 막힌 근관 등의 복잡한 근관 형태, 근관 내 석회화 물질, 영구치에 비해 상대적으로 협착된 치관부 치수강이 관찰되었다.

미세구조 분석방법을 활용한 서로 다른 밀도를 가진 기포콘크리트 특성 분석 (Investigation of Microstructural Characteristics of Foamed Concrete with Different Densities)

  • 정상엽;조수성;오서은
    • 대한토목학회논문집
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    • 제43권1호
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    • pp.1-7
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    • 2023
  • 서로 다른 밀도를 가진 기포콘크리트 시편을 생성하고, 각 시편의 특성을 SEM, micro-CT 등의 미세구조 분석 방법을 활용하여 분석하였다. 서로 다른 재령 일자에 대한 기포콘크리트 시편의 공극과 고체 구조를 분석함으로써, 재령 기간이 재료 특성 변화에 미치는 영향을 살펴보았다. 각 기포콘크리트 시편의 압축강도와 열전도도를 측정하여, 재료 물성과 미세구조적 특성 간의 상관관계에 대하여 분석하였으며, 결과를 통해 밀도와 재령 기간이 재료 강도에 미치는 영향을 확인하였다.

마이크로 CT를 이용한 BALB/C(흰쥐) 간문맥의 미세혈관 조영 영상 (Microvascular Contrast Image in Portal Veins of Rat using Micro-CT)

  • 이상호;임청환;정홍량;한범희;모은희;채규윤
    • 한국콘텐츠학회논문지
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    • 제10권9호
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    • pp.259-266
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    • 2010
  • 고해상도 엑스선 영상장치인 마이크로 CT를 이용, 흰쥐 간의 전체적인 문맥상과 각 간엽(lobe)의 미세혈관구조를 관찰하여 4개 분절 간엽의 구조를 영상화 하였고, 단축면상의 데이터를 3D영상으로 재구성한 미세혈관 구조의 입체적인 영상을 획득할 수 있는 마이크로 CT에 대한 유용성을 알아보고자 하였다. 5마리의 간 중에서 손상이 가장 적은 1개의 간을 4 개의 분절 간엽으로 각각 절단하여 문맥의 미세구조를 이차원으로 구성하였으며, MIP기법을 이용하여 간 문맥 전체 미세혈관의 3D영상을 얻었으며, 각 간엽의 미세혈관은 6분지까지 관찰할 수 있었다. 6 분지까지의 크기를 측정한 결과 평균치는 1 branch : $0.51mm{\pm}0.08$, 2 branch : $0.32mm{\pm}0.12$, 3 branch : $0.23mm{\pm}0.11$, 4 branch : $0.19 mm{\pm}0.08$, 5 branch : $0.13mm{\pm}0.06$, 6 branch : $70.5{\mu}m{\pm}14.1$ 로 측정되었다. 본 연구의 실험 결과에서 획득한 3차원의 입체 영상과 미세혈관 구조의 발견은 향후 고해상력의 영상을 얻을 수 있는 마이크로 CT가 많이 이용될 수 있을 것으로 기대된다.

마이크로버블에 의한 상추의 세척효과 및 저장 중 품질변화 (Wahsing Effect of Micor-Bubbles and Changes in Quality of Lettuce (Lacutuca sativa L.) during Storage)

  • 이선아;윤예리;권기현;김병삼;김상희;차환수
    • 한국식품저장유통학회지
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    • 제16권3호
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    • pp.321-326
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    • 2009
  • 마이크로버블을 이용한 세척시간과 세척방법에 따라 처리한 상추의 세척효과와 저장 중 품질 변화를 살펴본 결과는 다음과 같다. 세척시간 설정을 위한 실험을 통해 마이크로버블로 1, 3, 5분간 세척하여 미생물변화, 관능검사, 세척된 정도를 측정한 결과 5분간 처리한 시료가 가장 좋은 결과를 나타냈다. 세척방법에 따라 전처리한 상추의 미생물 변화는 세척처리 한 직후 무세척(CT)구는 4.30 log CFU/g, 손세척(HW)구는 4.10 log CFU/g, 일반버블세척(BW)구는 3.98 log CFU/g, 마이크로버블세척(MW)구는 3.25 log CFU/g에서 저장 10일째에는 무세척(CT)구는 7.00log CFU/g, 손세척(HW)구는 6.19 log CFU/g, 일반버블세척(BW)구는 6.02 log CFU/g, 마이크로버블세척(MW)구는 5.89 log CFU/g로 마이크로버블처리구가 가장 적은 변화를 보였다. 관능검사에서는 일반버블세척(BW)구와 마이크로버블세척(MW)구가 무세척(CT)구와 손세척(HW)구보다 유의적으로 높게 평가되었으며, 일반버블세척(BW)구와 마이크로버블세척(MW)구는 유의적 차이를 보이지 않았다. 또한 잔류농약시험에서도 마이크로버블을 이용한 처리구가 대조구 보다 2-3배정도 제거효과를 보였다. 상추의 세척상태를 측정한 결과 손세척구와 일반버블처리구은 완전히 깨끗하게 세척되지 못한 반면 마이크로버블처리구는 이물질이 보이지 않아 세척효과가 큰 것으로 나타났다.