• 열처리공학회지
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• 제20권5호
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• pp.237-242
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• 2007

Friction coefficient of SM45C steel was surprisingly reduced with $H_2S$ and $C_3H_8$ gas during plasma sulf-nitriding. During the plasma sulf-nitriding, 100-700 sccm of $H_2S$ gas and 100 sccm of $C_3H_8$ gas were added and working pressure and temperature were 2 torr, $500-550^{\circ}C$, respectively. As $H_2S$ gas amount increased over 500 sccm, flake-like structures were developed on top of the nitriding layer and grain size of the nitriding layer were about 100 nm. The friction coefficient for the sample treated plasma sulf-nitriding under $N_2-H_2S$ gas was 0.4 - 0.5. The structure became more finer and amorphous-like along with $N_2-H_2S-C_3H_8$ gas and the nano-sized surface microstructures resulted in high hardness and significantly low friction coefficient of 0.2.

• Smart Structures and Systems
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• 제8권1호
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• pp.119-137
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• 2011

A bio-inspired two-mode structural health monitoring (SHM) system based on the Na$\ddot{i}$ve Bayes (NB) classification method is discussed in this paper. To implement the molecular biology based Deoxyribonucleic acid (DNA) array concept in structural health monitoring, which has been demonstrated to be superior in disease detection, two types of array expression data have been proposed for the development of the SHM algorithm. For the micro-vibration mode, a two-tier auto-regression with exogenous (AR-ARX) process is used to extract the expression array from the recorded structural time history while an ARX process is applied for the analysis of the earthquake mode. The health condition of the structure is then determined using the NB classification method. In addition, the union concept in probability is used to improve the accuracy of the system. To verify the performance and reliability of the SHM algorithm, a downscaled eight-storey steel building located at the shaking table of the National Center for Research on Earthquake Engineering (NCREE) was used as the benchmark structure. The structural response from different damage levels and locations was collected and incorporated in the database to aid the structural health monitoring process. Preliminary verification has demonstrated that the structure health condition can be precisely detected by the proposed algorithm. To implement the developed SHM system in a practical application, a SHM prototype consisting of the input sensing module, the transmission module, and the SHM platform was developed. The vibration data were first measured by the deployed sensor, and subsequently the SHM mode corresponding to the desired excitation is chosen automatically to quickly evaluate the health condition of the structure. Test results from the ambient vibration and shaking table test showed that the condition and location of the benchmark structure damage can be successfully detected by the proposed SHM prototype system, and the information is instantaneously transmitted to a remote server to facilitate real-time monitoring. Implementing the bio-inspired two-mode SHM practically has been successfully demonstrated.

• Journal of Pharmaceutical Investigation
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• 제31권3호
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• pp.191-196
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• 2001

Biodegradable polymeric microspheres were studied for their usefulness as carriers for the delivery of vaccine antigens. However, protein antigen could be denatured during microencapsulation processes due to the exposure to the organic phase and stress condition of cavitation and shear force. Therefore this study was carried out to re-evaluate the degree of protein denaturation during microencapsulation with poly(lactide-co-glycolide) (PLGA) copolymer. PLGA microspheres containing ovalbumin (OVA), prepared by W/O/W multiple emulsification method, were suspended in pH 7.4 PBS and incubated with shaking at $37.5^{\circ}C$. Drug released medium was collected periodically and analyzed for protein contents by micro-BCA protein assay. In order to evaluate the protein integrity, release medium was subjected to the analyses of SDS-PAGE and size exclusion chromatography (SEC). And enzyme-linked immunosorbent assay (ELISA) was introduced to measure the immunoreactivity of entrapped OVA and to get an insight into the three-dimensional structure of epitope. The structures of entrapped protein were not affected significantly by the results of SDS-PAGE and SEC. However, immunoreactivity of released antigen was varied, revealing the possibility of protein denaturation in some microspheres when it was evaluate by ELISA method. Therefore, in order to express the degree of protein denaturation, antigenicity ratio (AR) was obtained as follows: amount of immunoreactivity of OVA/total amount of OVA released ${\times}100(%)$. ELISA method was an efficient tool to detect a protein denaturation during microencapsulation and the comparison of AR values resulted in more accurate evaluation for immunoreactivity of entrapped protein.

• 한국분말재료학회지
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• 제20권4호
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• pp.269-274
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• 2013

The present work investigated the dispersion behavior of $Y_2O_3$ particles into AISI 316L SS manufactured using laser cladding technology. The starting particles were produced by high energy ball milling in 10 min for prealloying, which has a trapping effect and homogeneous dispersion of $Y_2O_3$ particles, followed by laser cladding using $CO_2$ laser source. The phase and crystal structures of the cladded alloys were examined by XRD, and the cross section was characterized using SEM. The detailed microstructure was also studied through FE-TEM. The results clearly indicated that as the amount of $Y_2O_3$ increased, micro-sized defects consisted of coarse $Y_2O_3$ were increased. It was also revealed that homogeneously distributed spherical precipitates were amorphous silicon oxides containing yttrium. This study represents much to a new technology for the manufacture and maintenance of ODS alloys.

• Journal of Korean Neurosurgical Society
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• 제58권6호
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• pp.571-577
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• 2015

Direct removal of beak-type ossification of posterior longitudinal ligament at thoracic spine (T-OPLL) is a challenging surgical technique due to the potential risk of neural injury. Slipping off the cutting surface of a high-speed drill may result in entrapment in neural structures, leading to serious complications. Removal of T-OPLL with an ultrasonic osteotome, utilizing back and forth micro-motion of a blade rather than rotatory-motion of drill, may reduce such complications. We have applied the ultrasonic osteotome for posterior circumferential decompression of T-OPLL for three consecutive patients with beak-type OPLL and have described the surgical techniques and patient outcomes. The preoperative chief complaint was gait disturbance in all patients. Japanese orthopedic association scores (JOA) was used for functional assessment. Scores measured 2/11, 5/11, 2/11, and 4/11 for each patient. The ventral T-OPLL mass was exposed after posterior midline approach, laminotomy and transeversectomy. The T-OPLL mass was directly removed with an ultrasonic osteotome and instrumented segmental fixation was performed. The surgeries were uneventful. Detailed surgical techniques were presented. Gait disturbance was improved in all patients. Dural tear occurred in one patient without squeal. Postoperative JOA was 6/11, 10/11, 8/11, and 8/11 (recovery rate; 44%, 83%, 67%, and 43%) respectively at 18, 18, 10, and 1 months postoperative. T-OPLL was completely removed in all patients as confirmed with computed tomography scan. We hope that surgical difficulties in direct removal of T-OPLL might be reduced by utilizing ultrasonic osteotome.

• 한국진공학회지
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• 제11권4호
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• pp.194-200
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• 2002

MOCVD(metal-organic chemical vapor deposition) Cu 박막을 여러 조건에서 열처리를 행하여 그 전기적 특성과 미세구조의 변화를 통해 적절한 열처리 조건을 찾고 그 효과를 조사하였다. Ar 1 torr, $400^{\circ}C$에서 열처리를 거친 Cu 박막의 비저항이 1.98 $\mu$Ω.cm로 가장 낮게 나타났으며, 결정성의 경우도 $I_{(111)}/I_{(200)}$의 비가 2.03에서 3.11로 열 처리를 거치지 않았을 경우와 비교해서 약 50% 정도 향상된 값을 나타내었다. 열처리 후의electromigration(EM) 테스트에서는 Ar 1 torr, $400^{\circ}C$에서 열처리를 거친 배선이 EM에 대한 가장 높은 저항성을 보였다. 이것은 열처리 후 낮은 비저항, (111) 결정면의 성장, 그리고 표면 거칠기의 감소에서 기인한 것이다.

• Water Engineering Research
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• 제6권3호
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• pp.131-147
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• 2005

Today, a trend that tries to return the artificial space of a river to a natural one is expanding. But in Korea, which lies in the monsoon climate zone, rivers endure flood damage every year. Moreover, climatic change from global warming causes severe variations in precipitation patterns. Until recently, river restoration practices in Korea have followed partial restoration. These restorative treatments transformed artificial structures of the stream to natural ones and introduced natural vegetation by imitating natural or semi-natural streams. Treatment transformed the riparian structure and increased the diversity of micro-topography and vegetation. Furthermore, restoration recovered species composition, increased species diversity, and inhibited the establishment of exotic species. In particular, the Suip stream, which was left to its natural process for approximately 50 years, recovered its natural features almost completely through passive restoration. An urban stream, the Yangjae, and a rural stream, the Dongmoon, were restored partially by applying ecological principles. On the contrary, technological treatment applied to recover flood damage induced species composition far from the natural vegetation and decreased species diversity. Additionally, this treatment increased exotic species. The same results were found also in benthic invertebrate and fish fauna. The above-mentioned results reflect the importance of ecological considerations in river management.

• Journal of the Optical Society of Korea
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• 제19권1호
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• pp.69-73
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• 2015

The mesothelium is an essential lining for maintaining the normal homeostasis of the closed body cavity and a central component of pathophysiologic processes. The mesothelium has been known as the end target for asbestos which induces asbestos-related lung diseases. Malignant mesothelioma (MM) is a rare and fatal neoplasm predominantly due to asbestos exposure. Adaptation of an advanced and reliable technology is necessary for early detection of MM because it is difficult to diagnose this disease in its early stages. Optical coherence tomography (OCT) provides cross-sectional images of micro-tissue structures with a resolution of $2-10{\mu}m$ that can image the mesothelium with a thickness of ${\sim}100{\mu}m$ and, therefore, enable investigation of early development of MM. The mesothelium is typically located at the pleura and tunica vaginalis of the scrotum. In this study, we developed animal window models in the above two anatomical sites to visualize mesothelial layers within the mesothelium. OCT images at the two locations were also acquired.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 추계 학술발표회 제20권2호
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• pp.753-756
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• 2008

일반 콘크리트에 비해 상대적으로 높은 인성과 연성의 특징을 갖는 HPFRCC는 과도한 하중을 받는 구조 부재 혹은, 내구적으로 취약한 부재 등에 사용될 수 있으며, 기존의 연구에 의하면 PVA섬유를 이용한 HPFRCC의 경우 혼입률 2%에서 가장 높은 휨 성능이 나타난다고 알려져 있다. 이에 본 연구에서는 길이가 다른 두 종류의 PVA 섬유를 사용하여 상대적으로 짧은 섬유는 작은 균열(microcrack)을, 상대적으로 긴 섬유는 큰 균열(macrocrack)을 보다 효과적으로 제어하는 최적혼입비를 찾기 위하여 전체 PVA 혼입률을 2%로 고정시킨 채 두 섬유의 혼입률을 달리하여 각 혼입비에 따른 압축 및 휨 강도 테스트를 실시하였다. 또한 강섬유와 PVA 섬유를 동시에 하이브리드 보강한 콘크리트 부재에 대해서도 같은 실험을 실시하여 비교 분석하여 가장 높은 휨 성능을 나타낼 수 있는 최적배합을 찾고자 한다. 실험 결과 1.6%의 단섬유(12mm)와 0.4%의 장섬유(30mm)로 이루어진 시편에서 가장 높은 휨 성능을 보였으며, 2%의 PVA 섬유가 혼입된 부재에 대하여 소량의 강섬유 혼입 시 휨 성능이 다소 향상 되지만 많은 혼입량은 오히려 휨 성능의 저하를 초래하였다.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 추계 학술발표회 제20권2호
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• pp.809-812
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• 2008

지난 수년간 콘크리트의 염소이온 침투와 유관되어 실험방법론 및 해석적 모델 기법의 개발에 많은 발전이 있어왔다. 그러나 실제 콘크리트 구조물에는 다소의 균열이 존재하며 이는 장기 내구성에 큰 영향을 줄 수 있음에도 불구하고, 대부분의 연구들은 비균열의 콘크리트를 대상으로 연구되어 온 문제점이 있었으며 균열이 존재하는 콘크리트의 염소이온 침투에 대한 연구는 매우 드문 실정이다. 본 연구의 저자는 단기 촉진실험에 의하여 균열이 염소이온에 미치는 영향을 살펴보았다. 그러나 신뢰성있는 결과를 얻기 위해서는 장기 실험을 통한 고찰이 필요하다. 본 연구의 목적은 장기 및 단기 실험결과를 비교하였는데, 자기치료 효과에 의하여 균열이 시간이 경과함에 따라 감소하는 뚜렷한 경향을 확인할 수 있었다.이러한 경향은 균열 폭이 클수록 자기치료에 의한 균열감소 효과가 더욱 뚜렷하였다.