• Women's Health Nursing
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• v.24 no.3
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• pp.297-309
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• 2018

Purpose: To develop Pregnancy Risk symptom Perception Scale (PRPS) and evaluate its validity and reliability. Methods: A preliminary 30-item version of PRPS was developed through literature review, in-depth interview, and Content Validity. Each item was scored on a four-point Likert scale. The preliminary scale was developed based on 301 pregnant women who visited a hospital. Date were analyzed using item analysis, factor analysis, confirmatory factor analysis, Pearson's correlation coefficients, and Cronbach's ${\alpha}$ (0.90 for total item, 0.80 to 0.88 for factors). Results: The PRPS consisted of 27 items. Three factors (physical, environmental, and emotional factors) explained 55% of the total variance. Cronbach's Criterion validity was supported by comparison with the Perception of Pregnancy Risk Questionnaire (r=0.34). In reliability test, the reliability coefficient of pregnancy risk symptom perception was high at 0.90. Conclusion: These results suggest that the pregnancy risk symptom perception scale developed in this study comprises items that can assess the level of pregnant women's pregnancy risk symptom perception in Korea. Its validity and reliability were proven. PRPS can be utilized to measure pregnant women's risk symptom perception during pregnancy. PRPS will contribute to the development of systematic prenatal care and effective risk management.

• Journal of Korean Academy of Nursing
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• v.47 no.3
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• pp.319-331
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• 2017

Purpose: The purpose of this study was to develop a scale to evaluate posttraumatic growth in patients with cancer and to examine the validity and reliability of the scale. Methods: A literature review, semi-structured patient interviews and an expert panel consultation produced a 27 preliminary item questionnaire. Participants were 150 cancer patients recruited to test the reliability and validity of the preliminary scale. Data were analyzed using item analysis, exploratory factor analysis, convergent validity and internal consistency. Results: Item reduction and exploratory factor analysis led to 23 items, grouped into five subscales which were labelled new possibilities (6 items), coping skills (5 items), preciousness of life (5 items), relating to others (4 items), and personal strength (3 items). Convergent validity was evaluated by total correlation with the Functional Assessment of Cancer Therapy-General (r=.45, p<.001). The final scale demonstrated satisfactory internal consistency (Cronbach's ${\alpha}$ =.94). Conclusion: Findings from this study indicate that the Cancer-Specific Posttraumatic Growth Inventory has validity and reliability and is considered to be appropriate for assessing posttraumatic growth in patients with cancer.

• The Journal of Korean Academic Society of Nursing Education
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• v.26 no.4
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• pp.366-373
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• 2020

Purpose: The study aimed to investigate the relationship between moral distress and the quality of nursing care. Methods: This cross-sectional correlation study included nurses working at oncology nursing units of two secondary general hospitals in Seoul and Gyeonggi-do, Korea. A total of 207 nurses participated. Moral distress was measured by the Moral Distress Scale-Revised Nurse Questionnaire and quality of nursing care was evaluated by the Quality of Oncology Nursing Care Scale. Data were collected from October 5 to 31, 2018. Data analysis included descriptive statistics, independent t-test, ANOVA, Pearson's correlation coefficient and multiple regression analysis. Results: The quality of oncology nursing care showed a negative correlation with moral distress (r=-.19, p=.007). The factors affecting the quality of oncology nursing care were religion (β=-.22, p=.001), clinical experience in oncology units (β=.27, p=.007), and moral distress (β=-.16, p=.018). Moral distress showed a statistically significant predictive power of 13% in the regression model (F=8.70, p=<.001). Conclusion: The findings of this study suggest that management of moral distress is important to increase the quality of oncology nursing care.

• Bulletin of the Korean Chemical Society
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• v.10 no.2
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• pp.177-184
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• 1989

The structure of cholesteryl isobutyrate, $(CH_3)_2CHCOOC_{27}H_{45}$, was determined by single crystal X-ray diffraction methods. Cholesteryl isobutyrate crystallized monoclinic space group $P2_1$, with a = 15.115 (8)${\AA}$, b = 9.636 (5)${\AA}$, c = 20.224 (9)${\AA}$, ${\beta}$ = 93.15 (5)$^{\circ}$, z = 4, $D_c = 1.03 g/cm^3 $and Dm= 1.04 g/$cm^3$. The intensity data were measured for the 3417 reflections, within $sin{\theta}/{\lambda} = 0.59{\AA}^{-1}$, using an automatic four-circle diffractometer and graphite monochromated Mo-$K_{\alpha}$ radiation. The structure was solved by fragment search Patterson methods and direct methods and refined by full-matrix least-squares methods. The final R factor was 0.129 for 2984 observed reflections. The two symmetry-independent molecules (A) and (B) are almost fully extended. The molecules are in antiparallel array forming monolayers with thickness $d_{100}$ = 15.2${\AA}$, and molecular long axes are nearly parallel to the [$\bar{1}$01] directions. The two distinct molecules form separate stacks with almost the same orientations, but with differing degrees of steroid overlap. Thers is a close packing of cholesteryl groups within the monolayers. The packing type is similar to those of cholesteryl hexanoate and cholesteryl oleate.

• The Korea Journal of Herbology
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• v.27 no.3
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• pp.67-74
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• 2012

Objectives : The present study was designed to investigate effects of Ssanghwa-tang (Shu$\bar{a}$nghu$\bar{a}$-g$\bar{e}$ng) on oxidation/reduction reaction-related and aging-related enzymes $in$ $vitro$. Methods : We performed MTT assay, collagenase inhibition assay, elastase inhibition assay, tyrosinase inhibition assay, DPPH free radical scavenging assay, SOD-like activity and xanthine oxidase (XO) inhibition assay. Results : The 50% ethanol (EtOH) extract of Ssanghwa-tang (SHT) showed 55% inhibition of collagenase activity, and 42% inhibition of elastase activity at 1 mg/ml concentration. Also it's treatment showed 18% inhibition of tyrosinase activity, to relate whitening effect, at the same dose of 50% ethanol extract of SHT. Antioxidant activities were determined by DPPH radical scavenging, XO inhibiting activity and SOD-like activity. These scavenging, XO-inhibiting and SOD-like activities were measured in 80%, 75%, and 28% inhibitions, respectively, at a 1 mg/ml treated dose, compared to those of control. The inhibitory effects of 50% EtOH extract on aging and oxidation-related enzyme activities were higher than those of water extract and 95% EtOH extract. Conclusions : Taken together, our findings suggest that the SHT has potential and applicable benefits for development of cosmetics to have anti-aging (anti-wrinkle and whitening) and anti-oxidation functions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.9
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• pp.243-250
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• 2018

This descriptive study was conducted to investigate the factors affecting the mental health of university students. Data were collected from 312 university students by questionnaires and analyzed by t-test, ANOVA, Scheffe's test, correlation analysis, and multiple regression analysis. The mean scores were 1.69, 1.87 and 2.21 out of 5 on Likert scales for mental health, campus life stress and employment stress, respectively. The mean score for self-esteem was 2.27 out of 4 on a Likert scale. Gender and number of close friends affected mental health significantly. Moreover, there was a negative correlation between mental health and self-esteem(r=-.426, p<0.001), while a positive correlation was observed between mental health and campus life stress (r=0.660, p<0.001), and mental health and employment stress(r=.517, p<0.001). Multiple regression analysis showed that campus life stress (${\beta}=.545$), self-esteem(${\beta}=-.145$), and employment stress (${\beta}=0.067$) affected mental health in order, and the three research variables led to a 45.2% prediction for mental health of university students. Based on the results of this study, effective systematic plans for decreasing campus life stress and employment stress and increasing self-esteem are needed to improve the mental health of university students.

• Korean Journal of Breeding Science
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• v.41 no.4
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• pp.591-594
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• 2009

A new gerbera variety "Red Line" was released by the National Institute of Horticultural & Herbal Science (NIHHS) in 2008. A cross was made between "Mirage" with orange and double and "Rose" with red and semi-double in 2005. After investigation of the characteristics for four years (from 2005 to 2008), it was selected specially for the use of cut flower. "Red Line" is a vigorous cultivar with red (RHS R44B), black center and semi-double. The average flower diameter is 12.7 cm, large flower. And inner ray floret and disc diameter are 8.10 cm and 2.80 cm, respectively. It produces a large yield with continuous supply of flowers and has adequate peduncle height. We believe that "Red Line" has a great potential for expanding cultivated area of domestic gerbera cultivars and increasing farmers-income.

• Journal of Korean Clinical Nursing Research
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• v.28 no.3
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• pp.251-259
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• 2022

Purpose: This study aimed to identify the relationships among emotional labor, grit, and job satisfaction of pediatric nurses and factors affecting job satisfaction. Methods: A cross-sectional study was conducted on 137 pediatric nurses working in a general hospital in Seoul. Data were collected from January 1, 2022 to January 31. The data were analyzed using SPSS/WIN version 28.0.1.1. Results: The mean score of job satisfaction was 3.63±0.43 (out of 5), emotional labor was 3.70±0.39 (out of 5), and grit was 2.90±0.30 (out of 4). Job satisfaction had positively correlated with emotional labor (r=.27, p=.002) and grit (r=.65, p<.001). The regression analyses showed subcategories of grit had a significant influence on job satisfaction. The factors significantly affecting job satisfaction were persistence to achieve long-term goals (β=.39, p<.001), patient-oriented intrinsic motivation (β=.30, p<.001), and passion to become a nursing professional (β=.21, p=.004). Conclusion: These results suggested a need to increase grit for improving the job satisfaction. Furthermore, it would be necessary to develop a diverse program to increase job satisfaction for pediatric nurses by improving grit.

• Journal of the Korea Convergence Society
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• v.10 no.9
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• pp.311-321
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• 2019

A Convergence study was conducted to investigate the factors influencing the burnout in caregivers and to present a strategy for effective program development. The subjects of this study were 185 caregivers who had worked for 6 months in a G city Nursing facility and distributed the self-reported questionnaire in September 2015. Data were analyzed using t-test, one-way ANOVA, $Scheff{\acute{e}}$ test, Pearson's correlation coefficient and Stepwise multiple regression analysis were performed. According to the results, the identified influencing factors were stress of personal role and daily work factors(${\beta}=.307$, p<.001), stress of relationship with supervisors(${\beta}=.186$, p<.021), confidence(${\beta}=.182$, p<.005), passive coping(${\beta}=.140$, p<.035) with burnout in caregivers. The explanatory power($R^2$) by 4 variables was 27.5%. Based on the results of this study, it would be necessary to develop an burnout reduction program that can reduce stress, increase self-confidence, and diversify coping strategies in order to reduce burnout of caregivers.

• Journal of Applied Biological Chemistry
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• v.49 no.1
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• pp.24-27
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• 2006

Four ursane-type triterpenoids, 2${\alpha}$,3${\alpha}$,19${\alpha}$-trihydroxy-24-norurs-4(23),12-dien-28-oic acid (1), 4(R),23-epoxy-2${\alpha}$,3${\alpha}$,19${\alpha}$-trihydroxy-24-norurs-12-en-28-oic acid (2), myrianthic acid (3), and tormentic acid (4), and a phenolic compound, ethyl gallate (5), from an EtOAc-soluble extract of the stems of Rumex japonicus, were subjected to in vitro bioassays to evaluate advanced glycation end products (AGEs) and rat lens aldose reductase (RLAR) inhibitory activity. Compounds 1 and 5 exhibited a significant inhibitory activity on AGEs formation with $IC_{50}$ value of 87 ${\mu}M$ and on RLAR with $IC_{50}$ value of 14.3 ${\mu}M$, respectively. Ethyl gallate (5) was isolated for the first time from this plant.