• 제목/요약/키워드: miR-25

검색결과 442건 처리시간 0.027초

연안내만해역에서 우점하는 주요적조생물의 성장과 세포체적의 관계 (Relationships between Cell Bio-volume and Growth Rate of Dominant Red Tide Organisms in the Coastal Water)

  • 백승호;주혜미
    • 환경생물
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    • 제30권1호
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    • pp.1-8
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    • 2012
  • To understand growth characteristics of eight dominant red tide species ($Prorocentrum$ $minimum$, $Heterocapsa$ $triquetra$, $Scrippsiella$ $trochoidea$, $Akashiwo$ $sanguinea$, $Chattonella$ $marina$, $Heterosigma$ $akashiwo$, $Amphidinium$ $carterae$ and $Rhodomonas$ $salina$) in the Korean coastal water, the growth rates were examined in relation with the impacts of water temperature and bio-volume. Of these, $P.$ $minimum$, $C.$ $marina$, $H.$ $akashiwo$, $A.$ $carterae$ and $R.$ $salina$ were eurythermal species with relatively high growth rates in a borad ranges (15 to $25^{\circ}C$) of water temperature. On the other hand, the growth rate of $H.$ $triquetra$, $S.$ $trochoidea$ and $A.$ $sanguinea$ were high in relatively mid temperature (optimum: $25^{\circ}C$) condition. In particular, $H.$ $triquetra$ was well adapted in low temperature of 5 to $15^{\circ}C$, implying that the species can survive and grows even at very low temperature. Based on results of our experiment, the growth characterestics of five eurythermal species and three mid temperature species may have dominated in Korean coastal water during summer season and fall season, respectively. Contrastively, the growth characteristics of $H.$ $triquetra$ make a consistently dominant during the cold winter season. In addition, the growth rates of large bio-volume species were lower than those of small bio-volume species, indicates that growth of single cells of several flagellates might be depended on the cells sizes.

전산화 단층촬영을 이용한 성인여성의 복부비만과 지질대사지표와의 연관성 (The Relationship of Abdominal Obesity and Lipid Profiles by Computed Tomography in Adult Women)

  • 김미영
    • 대한방사선기술학회지:방사선기술과학
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    • 제31권1호
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    • pp.33-39
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    • 2008
  • 복부비만은 2형 당뇨병과 고지혈증, 고혈압, 관상동맥질환 등의 심혈관계 질환의 주요 위험인자이며 특히 내장형 복부 비만인 경우 위험도가 더 크다고 알려져 있다. 이 연구에서는 2006년 4월부터 2007년 9월까지 일개 대학병원 비만 클리닉을 방문한 BMI 23 이상의 성인 여성 25명을 대상으로 하여 복부지방 CT를 실시하여 지질대사지표와의 상관성 및 내장지방 분포에 영향을 주는 요인을 분석하였다. 8시간 공복 후 채취한 정맥혈액을 이용하여 Glucose, TC, TG, HDL의 농도를 분석하였고, 안정시의 이완기 혈압과 수축기 혈압을 측정하였다. 연구결과 내장지방량은 TC와 TC/HDL과 음의 상관관계를 보였다. 통계적으로는 BMI, TAF, VSR이 통계적으로 유의한 차이가 있는 것으로 나타났다(p < .001). 내장지방량을 가장 잘 반영하는 지질대사지표는 TC와 TG, HDL인 것으로 나타났으며, 이 회기분석모델은 47%의 설명도를 가지고 있는 것으로 나타났다.

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M&L 자기성장 명상프로그램의 효과에 대한 연구 (The Study on Effects of M&L Self-Growth Meditation Program)

  • 이유진;김정숙;고경숙;서주희;오정란;김미영;강형원
    • 동의신경정신과학회지
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    • 제25권3호
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    • pp.225-234
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    • 2014
  • Objectives: The purpose of this study is to investigate the effects of M&L Self-Growth Meditation Program with Euro QOL-5 Dimension (EQ5D), Five Facet Mindfulness Questionnaire (FFMQ) and psychological test. Methods: 6 middle-age women have participated in the eight weeks of the M&L Self-Growth Meditation Program, and the program was executed once a week for about two hours. We evaluated EQ5D, FFMQ, Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), and State-Trait Anger Expression Inventory (STAXI) before and after the program in order to analyze the effects of M&L Self-Growth Meditation Program. Results: 1) EQ5D scores increased significantly (p<0.05), and overall physical condition scale( VAS) increased. 2) In the FFQM scores, value of Nonreactivity increased significantly (p<0.05), and total score increased. 3) Scores of BDI and STAI-S decreased significantly (p<0.05), and STAI-T, STAXI-S, STAXI-T, STAXI-O, STAXI-Su, and STAXI-R decreased. Conclusions: The results suggested that M&L Self-Growth Meditation Program improves the quality of life and mindfulness skill and has a positive responses to psychological problems-depression, anxiety, and anger.

기후변화에 따른 공간해상도별 토양유실량 평가 (Estimation of Soil Erosion for Each Spatial Resolution on the Climate Change)

  • 이미선;박종윤;정인균;김성준
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2008년도 학술발표회 논문집
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    • pp.529-533
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    • 2008
  • 본 연구는 미래기후변화가 공간해상도(5, 10, 30m)에 따른 토양유실량의 변화에 미치는 영향을 분석하고 자하였다. 연구대상지역은 경안천 최상류에 위치한 $1.16km^2$의 농촌 소유역을 대상으로 공간해상도별(5, 10, 30m) RS 및 GIS 자료를 생성하고, GIS 기반의 RUSLE(Revised Universal Soil Loss Equation) 모형을 채택하여 토양유실량을 분석하였다. 기후변화 시나리오는 IPCC(Intergovernmental Panel on Climate Change)에 서 제공하는 GCM(Global climate model) 중에서 MIROC3.2 hire의 A1B, B1 시나리오를 이용하였으며, 과거 30년간(1977-2006)의 기상자료 통계정보를 기준으로 Change Factor Downscaling 기법을 적용하여 2020s년 (2010-2039), 2050s년(2040-2069), 2080s년(2069-2099) 전후의 각 30년간의 미래 강우량을 재생산하여 사용하였다. 그 결과 강수량은 2080s년에 A1B 시나리오의 경우 연평균 강수량은 270.37mm, 최대 강수량은 65.71mm 증가하였고, B1 시나리오의 경우 연평균 강수량은 37.11mm, 최대 강수량은 48.46mm 증가하는 것으로 나타났다. 구축한 미래 강우량을 RUSLE 인자 중 R 인자에 적용하여 2020s년, 2050s년, 2080s년의 토양유실량을 분석한 결과, 미래강수량이 증가함에 따라 공간해상도별 토양유실량도 증가하는 것으로 분석되었다. 평균토양유실량을 시나리오별로 보면, A1B 시나리오의 경우 2080s을 기준으로 1/5,000 scale에서는 약 0.18 ton/ha/year, 1/25,000 scale에서는 약 0.07 ton/ha/year, 1/50,000 scale에서는 약 0.07 ton/ha/year의 유실량이 각 공간해상도별로 증가하였다. B1 시나리오의 경우 2080s을 기준으로 1/5,000 scale에서는 약 0.03 ton/ha/year, 1/25,000 scale에서는 약 0.01 ton/ha/year, 1/50,000 scale에서는 약 0.01 ton/ha/year의 토양유실량이 증가한 것으로 분석되었다.

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한의학 연구개발과제 분류에 관한 연구 (A Classification for Research Projects in Oriental Medicine Field)

  • 김상균;김철;장현철;예상준;송미영
    • 정보관리학회지
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    • 제25권4호
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    • pp.309-326
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    • 2008
  • 국가 R&D 사업관리 시스템에서는 국내의 국가 연구개발과제 정보를 관리하고 검색할 수 있도록 하고 있다. 특히 연구개발과제들을 분류하고 다양한 검색 및 분석 서비스를 제공하기 위해서 다양한 분류체계를 이용하고 있다. 하지만 하나의 분류체계에 대해 하나의 분류만 입력 가능하도록 하고 있기 때문에 과제의 성격을 명확히 파악하는데 어려움이 있다. 또한 연구개발과제를 위한 분류체계는 모든 분야에 대한 일반적인 분류를 제공하고 있으나 한의학과 같은 특정 분야에 맞는 분류체계는 제공하지 않고 있다. 반면에 한의학 분야에서는 한의학에 대한 분류체계 연구가 진행되어 왔지만 이 분류체계 또한 한의학 전반에 관한 일반적인 분류이기 때문에 한의학 연구개발과제를 위한 분류로는 적합하지 않는 문제가 있다. 따라서 본 연구에서는 이러한 문제를 해결하기 위해 한의학 분야의 연구개발과제들의 성격을 명확히 파악하고 검색 및 분석에 활용할 수 있는 분류를 제안한다.

TiO2 sol-gel 합성에 의한 파라 아라미드 섬유의 내광성 증진 연구 (Improving the Photo-stability of p-aramid Fiber by TiO2 Nanosol)

  • 박성민;권일준;심지현;이재호;김삼수;이문철;최종석
    • 한국염색가공학회지
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    • 제25권2호
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    • pp.126-133
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    • 2013
  • Although para-aramid fibers poss higher mechanical properties, they show very low resistance to sunlight exposure. This paper studied on the effect of nano-sol coated $TiO_2$ to improve the photo-stability of p-aramid fibers. Titanium dioxides were prepared by sol-gel method from titanium iso-propoxide at different R ratio ($H_2O$/titanium iso-propoxide). All samples were characterized by XRD, TEM and UV-vis spectrometer. The mechanical properties of p-aramid fabrics by $TiO_2$ nano-sol coating before and after sunlight irradiation were measured with tensile tester. XRD pattern of titanium dioxide particles was observed by mixing phase together with rutile and anatase type. The results showed, after sunlight irradiation, the decreased mechanical properties of the fiber. Furthermore, the sunlight irradiation obviously deteriorated the surface and defected areas of the fiber severely by photo-induced chain scission and end group oxidation in air.

충북지역 일부 고등학생의 스트레스 상태와 청소년 영양지수를 이용한 영양상태와의 관련성 (Association between Stress and Nutritional status of High School Students in Chungbuk using Nutrition Quotient for Korean Adolescents)

  • 김인영;최미경
    • 대한지역사회영양학회지
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    • 제25권5호
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    • pp.361-373
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    • 2020
  • Objectives: The purpose of this study was to investigate the relationship between stress levels and eating habits in adolescents. Methods: A total of 453 male and female high school students were surveyed to ascertain their stress levels, Nutrition Quotients for Korean Adolescents (NQ-A), and stress-related eating behavior. Results: The average age of the subjects was 18 and they were mostly from nuclear families. Their average daily conversation time with their parents was between 10 to 30 minutes. The average sleep time for female students was observed to be less than that of male students. The satisfaction level of academic achievement of female students was significantly lower than that of the male students (P < 0.001). The average stress level score for female students was 2.7 out of 5, which was significantly higher than the male student's score of 2.4 (P < 0.001). The eating speed of male students was related to stress levels. Both male and female students ate more and craved spicy food when under stress. All male and female students had significantly ascending NQ-A scores rising in the order of stress from 'low level' to 'medium level', to 'high level' (P < 0.001). There was a significant negative correlation between the stress score and the NQ-A score adjusted for general characteristics (r = -0.29, P < 0.001). Conclusions: Since stress and NQ-A were negatively correlated in high school students, higher stress levels can be associated with irregular eating habits and negative eating behavior. Therefore, stress management and nutrition education focusing on stress status are needed for adolescents.

2011-2016년 의학교육평가컨소시엄 임상종합평가의 효과성 (Effectiveness of Medical Education Assessment Consortium Clinical Knowledge Mock Examination (2011-2016))

  • 이상엽;이예리;김미경
    • 의학교육논단
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    • 제20권1호
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    • pp.20-31
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    • 2018
  • Good assessment is crucial for feedback on curriculum and to motivate students to learn. This study was conducted to perform item analysis on the Medical Education Assessment Consortium clinical knowledge mock examination (MEAC CKME) (2011-2016) and to evaluate several effects to improve item quality using both classical test theory and item response theory. The estimated difficulty index (P) and discrimination index (D) were calculated according to each course, item type, A (single best answer)/R (extended matching) type, and grading of item quality. The cut-off values used to evaluate P were: >0.8 (easy); 0.6-0.8 (moderate); and <0.6 (difficult). The cut-off value for D was 0.3. The proportion of appropriate items was defined as those with P between 0.25-0.75 and D ${\geq}0.25$. Cronbach ${\alpha}$ was used to assess the reliability and was compared with those of the Korean Medical Licensing Examination (KMLE). The results showed the recent mean difficulty and decimation index was 0.62 and 0.20 for the first MEAC CKME and 0.71 and 0.19 for the second MEAC CKME, respectively. Higher grade items evaluated by a self-checklist system had better D values than lower grade items and higher grade items gradually increased. The preview and editing process by experts revealed maintained P, decreased recall items, increased appropriate items with better D values, and higher reliability. In conclusion, the MEAC CKME (2011-2016) is deemed appropriate as an assessment to evaluate students' competence and prepare year four medical students for the KMLE. In addition, the self-checklist system for writing good items was useful in improving item quality.

고에너지 볼 밀링을 이용한 Y-산화물 분산 Fe-기초내열합금 분말의 합성 및 미세조직 특성 (Synthesis and Microstructure of Fe-Base Superalloy Powders with Y-Oxide Dispersion by High Energy Ball Milling)

  • 임다미;박종관;오승탁
    • 한국재료학회지
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    • 제25권8호
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    • pp.386-390
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    • 2015
  • Fe-base superalloy powders with $Y_2O_3$ dispersion were prepared by high energy ball milling, followed by spark plasma sintering for consolidation. High-purity elemental powders with different Fe powder sizes of 24 and 50 mm were used for the preparation of $Fe-20Cr-4.5Al-0.5Ti-O.5Y_2O_3$ powder mixtures (wt%). The milling process of the powders was carried out in a horizontal rotary ball mill using a stainless steel vial and balls. The milling times of 1 to 5 h by constant operation (350 rpm, ball-to-powder ratio of 30:1 in weight) or cycle operation (1300 rpm for 4 min and 900 rpm for 1 min, 15:1) were applied. Microstructural observation revealed that the crystalline size of Fe decreased with an increase in milling time by cyclic operation and was about 15 nm after 3 h, forming a FeCr alloy phase. The cyclic operation had an advantage over constant milling in that a smaller-agglomerated structure was obtained. The milled powders were sintered at $1100^{\circ}C$ for 30 min in vacuum. With an increase in milling time, the sintered specimen showed a more homogeneous microstructure. In addition, a homogenous distribution of Y-compound particles in the grain boundary was confirmed by EDX analysis.

노인의 IoT 기반 스마트 건강관리서비스 이용의도에 미치는 영향 (A study on the Influence of Usage Intention of IoT Healthcare service for Elderly)

  • 홍성정;이성현;김경미
    • 한국융합학회논문지
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    • 제11권3호
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    • pp.341-349
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    • 2020
  • 본 연구는 기술수용모델을 기반으로 IoT 기반의 스마트 건강관리 서비스에 대한 노인들의 이용의도를 알아보고자 시도되었다. 본 연구에서는 전문적 지원, 개인화, 상호작용, 사용편의성을 외생변수로 하고, 매개 내생 변수로 인지된 유용성, 사용의도를 최종 내생변수로 선정하였다. 본 연구의 대상자는 노인복지센터를 이용하는 220명의 65세 이상 노인이었으며, 수집된 자료는 AMOS 25.0을 활용하여 분석하였다. 본 연구결과 전문가 지원, 개인화는 인지된 유용성에 유의한 영향을 나타내지 않았고, 상호작용, 사용편의성과는 유의한 차이가 있었다. 또한 인지된 유용성은 사용의도에 영향을 미치는 것으로 나타났다. 본 연구는 노인의 IoT기반 스마트 건강관리 서비스 이용의도를 구조적으로 검증함으로써 노인들의 이용의도를 높이기 위한 전략 마련에 기초자료로 사용될 수 있을 것으로 생각한다.