• 제목/요약/키워드: miR-25

검색결과 441건 처리시간 0.025초

일개 지역 고등학생의 인터넷 중독이 건강상태에 미치는 영향 (The Effect of High School Students' Internet Addiction on Their Health Status)

  • 박승미;박현주;장인순
    • 한국학교보건학회지
    • /
    • 제23권2호
    • /
    • pp.115-124
    • /
    • 2010
  • Purpose: The purpose of this study was to investigate the effect of high school students' internet addiction on their health status. Methods: The subjects of the present study were 237 high school students in KyongBuk province. Self-reporting questionnaire survey was conducted during the period from September to October 2009. Collected data were analyzed using SPSS PC+14.0 through descriptive statistics, t-test, ANOVA, Scheffe's test and stepwise multiple regression analysis. Results: With regard to internet addiction, 33.9% is at the early stage of internet addiction and 2.1% is severely addicted to internet. Health status was poorer in female, students with low economic status, less attention to children's health by parents, neglecting their children's internet use, single-parent, and severely addicted to internet. Factors significantly influencing on the health status included gender, internet addiction, parent's attitude about internet using time, interest in their children's health, economic status and internet using time ($R^2$=25.8%). Conclusion: The education program for preventing internet addiction considering these affecting factors is necessary.

Optimization of Medium Composition for Production of the Antioxidant Substances by Bacillus polyfermenticus SCD Using Response Surface Methodology

  • Lee, Jang-Hyun;Chae, Mi-Seung;Choi, Gooi-Hun;Lee, Na-Kyoung;Paik, Hyun-Dong
    • Food Science and Biotechnology
    • /
    • 제18권4호
    • /
    • pp.959-964
    • /
    • 2009
  • Production of the antioxidant substances by Bacillus polyfermenticus SCD was investigated using shake-flask fermentation. The one-factor-at-a-time method was first employed to determine the key ingredients for optimal medium composition, then further investigation of the medium composition was performed using response surface methodology (RSM). The antioxidant activity was measured using 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) assays. After screening various elements, fructose, tryptone, and $MgSO_4\;7H_2O$ were chosen as the main factors for study in the statistical experimental design. Central composite design (CCD) was then used to determine the optimal concentrations of these 3 components. Under the proposed optimized medium containing 2.8% fructose, 1.34% tryptone, 0.015% $MgSO_4\;7H_2O$), 0.5% NaCl, and 0.25% $K_2HPO_4$, the model predicted an antioxidant activity of 80.5% ($R^2=0.9421$. The actual experimental results were in agreement with the prediction.

VvpM Induces Human Cell Death via Multifarious Modes Including Necroptosis and Autophagy

  • Lee, Mi-Ae;Kim, Jeong-A;Shin, Mee-Young;Lee, Jeong K.;Park, Soon-Jung;Lee, Kyu-Ho
    • Journal of Microbiology and Biotechnology
    • /
    • 제25권2호
    • /
    • pp.302-306
    • /
    • 2015
  • VvpM, one of the extracellular metalloproteases produced by Vibrio vulnificus, induces apoptotic cell death via a pathway consisting of ERK activation, cytochrome c release, and activation of caspases-9 and -3. VvpM-treated cells also showed necrotic cell death as stained by propidium iodide (PI). The percentage of PI-stained cells was decreased by pretreatment with Necrostatin-1, indicating that VvpM-mediated cell death occurs through necroptosis. The appearance of autophagic vesicles and lipidated form of light-chain-3B in rVvpM-treated cells suggests an involvement of autophagy in this process. Therefore, the multifarious action of VvpM might be one of the factors responsible for V. vulnificus pathogenesis.

유연성 기판위에 스퍼터링 방법으로 증착한 CdS 박막의 전기적 특성 및 신뢰성 평가 (Electrical Properties and Reliability of CdS Thin Film Deposited by R.F. Sputtering)

  • 허성기;황미나;안준구;윤순길
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2010년도 하계학술대회 논문집
    • /
    • pp.26-26
    • /
    • 2010
  • Cadmium sulfide (CdS) thin film for flexible optical device applications were prepared at $H_2(Ar+H_2)$ flow ratios on polyethersulfon(PES) flexible polymer substrates at room temperature by radio frequency magnetron sputtering technique. The CdS thin films deposited at room temperature showed a (002) preferred orientation and the smooth surface morphologies. Films deposited at a hydrogen flow ratio of 25% exhibited a photo- and dark-sheet resistance of about 50 and $2.7{\times}10^5{\Omega}$/square, respectively. From the result of the bending test, CdS films exhibit a strong adhesion with the PES polymer substrates and the $Al_2O_3$ passivation layer deposited on the CdS films only shows an increase of the resistance of 8.4% after exposure for 120 h in air atmosphere.

  • PDF

간호대학생의 아동학대 지식, 태도, 지각된 행위통제력과 아동학대 사례별 신고의도 (Nursing Students' Knowledge, Attitudes, Perceived Behavior Control and Intention to Report Cases of Child Abuse)

  • 조경미;김은주
    • Child Health Nursing Research
    • /
    • 제22권2호
    • /
    • pp.145-152
    • /
    • 2016
  • Purpose: This study was designed to explore nursing students' knowledge, attitudes and intention to report cases of child abuse. Methods: A descriptive research design was used with a convenience sample of 202 nursing students. After explaining the purpose of the study, participants who signed the consent form were asked to complete a self-descriptive questionnaire, which included the Child Abuse Intension Scale (CARIS). Results: The number of correct answers for knowledge of child abuse and the law was 7.0 /13. The mean scores were, for attitude toward childrearing belief and discipline, $17.1{\pm}5.2$, for punishment and culpability of offender or victim, $24.6{\pm}4.1$, for professional responsibility, $30.5{\pm}5.1$, and for perceived behavioral control, $25.3{\pm}5.0$. The intended reporting behavior differed significantly by severity of abuse. Factors influencing the intention to report child abuse were attitude towards punishment of parents, professional responsibility, and perceived behavioral control ($R^2$=.133). Conclusion: On the basis of our finding, developing education programs to help nursing students detect child abuse and improve reporting rates is important. Thus, we suggests that nursing students be provided with educational protocol for detection and reporting of child abuse.

청소년의 가족환경지각과 정신건강과의 관계 (A Study on the Correlation between Perception of Family Environment and Mental Health of Boy's High School Students)

  • 오화선;김미예
    • 모자간호학회지
    • /
    • 제3권1호
    • /
    • pp.25-37
    • /
    • 1993
  • The purpose of this study was to investigate the relation between perception of family environment and mental health of boy's high school students. In order to obtain the appropriate data, a questionnaire was administered to 240 boy's high school 2nd-grade students in Pohang city from March 19 to March 28, 1992. The instruments used for this study were Moos's Family Environment Scale Form R and Kim's Symptom Check List-90. The conclusions were as follows : The level of perception of family environment was lower than mean score. Cohesion, achievement orientation, independence, organization, expressiveness were percepted high but active-recreational orientation, intellectual-cultural orientation were percepted low. Mental health of most respondents was well. The scores of obsessive-compulsive reaction and interpersonal sensitivity were high, the scores of somatization and phobia were low. General characteristic variables significantly related to the level of perception about family environment were father's occupation and mother's education level. There were no significant differences between general characteristic variables and mental health. There were mostly negative correlations between perception of family environment and mental health. Cohesion, expressiveness, independence, intellectual-cultural orientation, active-recerational orientation, moral-religious emphasis, organization were negatively correlated but conflict, achivement orientation, control were positively correlated. Cohesion, expressiveness, conflict, achivement orientation, active-recretional orientation, organization, control were significantly related, but independence intellectual-cultural orientation, moral-religious emphasis were no significant correlation.

  • PDF

Offsprings Produced by Transcervically Inseminating Frozen-thawed Semen into Uterus of a Estrus-induced Saanen Goat during Non-breeding Season

  • Yong, Hwan-Yul;Kim, Min-Ah;Bae, Bok-Soo;Kim, Seung-Dong;Jo, Shin-Il;Lim, Yang-Mook;Yoo, Mi-Hyun;Ha, Yong-Hee;Oh, Chang-Shik;Kim, Doo-Hee
    • 한국수정란이식학회지
    • /
    • 제25권2호
    • /
    • pp.89-92
    • /
    • 2010
  • We report herein the successful results of estrus induction, sperm cryopreservation and kids born by transcervical insemination of frozen-thawed semen in a Saanen goat. Flugestone acetate (FGA: 60 mg) was inserted into vagina for 15 days. The goat was intramuscularly injected with 400 IU PMSG and 200 IU hCG ($PG600^{(R)}$: Intervet, Korea) a day before withdrawal of the FGA sponge. Follicles and corpora lutea were identified on both ovaries by laparoscopy. Artificial insemination was performed 46 hours after removal of FGA sponge. The concentration of frozen-thawed semen was $3.975{\times}10^8/ml$ and 0.5 ml of frozen-thawed semen was transcervically inseminated into uterine body under anesthesia. Three kids, all females, were born 144 days after artificial insemination. This is the first report producing kids by transcervical insemination of frozen-thawed semen in a Saanen goat of which the estrus was induced by FGA sponges, PMSG and hCG during non-breeding season in Korea.

무가압 소결법에 의한 SiC-$TiB_2$계 도전성 복합체의 특성 (Properties of Pressureless Sintered SiC-$TiB_2$ Electroconductive Composites)

  • 박미림;주진영;신용덕;소병문
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2001년도 춘계학술대회 논문집 유기절연재료 전자세라믹 방전플라즈마 연구회
    • /
    • pp.118-122
    • /
    • 2001
  • The ${\beta}-SiC+TiB_2$ ceramic electroconductive composites were pressureless-sintered and annealed by adding 12wt% $Al_2O_3+Y_2O_3$(6 : 4wt%) powder as a function of sintering temperature. The relative density is over 78.83% of the theoretical density and increased with increasing sintering temperature. The phase analysis of the composites by XRD revealed of $\alpha$-SiC(6H), $TiB_2$, $Al_5Y_2O_{12}$ and $\beta$-SiC(15R). Flexural strength showed the highest of 140 MPa for composites sintered at $1900^{\circ}C$. The vicker's hardness increased with increasing sintering temperature and showed the highest of 4.07 GPa at $1900^{\circ}C$. Owing to YAG, the fracture toughness showed the highest of 4.07 $MPa{\cdot}m^{1/2}$ for composites at $1900^{\circ}C$. The electrical resistivity was measured by the Pauw method from $25^{\circ}C$ to $700^{\circ}C$. The electrical resistivity of the composites showed the PTCR(Positive Temperature Coefficient Resistivity).

  • PDF

아라비카 원두의 산지 및 수확방법에 따른 이화학적 특성 및 항산화성 (Comparative Composition of Orgainc and Inorgainc Arabica Beans and Their Antioxidant Characteristics)

  • 지은정;유경미;황인경
    • 한국식품조리과학회지
    • /
    • 제25권4호
    • /
    • pp.421-426
    • /
    • 2009
  • The objective of this study was to evaluate the antioxidant and physiological The objective of this study was to evaluate the antioxidant and physiological activities of organic and inorganic coffee based on flavonoid composition. Organic and inorganic coffee varieties were prepared with Brazil arabica bean and Columbia arabica bean, respectively. Color values (Lightness, redness, and yellowness), mineral contents, total phenol content, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, individual flavonoids, and sensory characteristics were then measured in the espresso of each coffee bean. The pH, Brix, and color difference between organic coffee and inorgainc coffee did not correlate with the harvest method. Coffee varieties were more influential on physiological properties, and were markedly more influential than the mineral content. Total phenolics had a higher correlation with DPPH radical scavenging activity ($r^2$=0.832). Depending on the harvesting method, significant differences (p<0.05) were shown in aroma, color, and overall acceptability in sensory evaluation.

간호·간병 통합병동에 입원한 노인환자의 낙상예방교육 효과 (Effect of Fall Prevention Education for Older Patients in Comprehensive Nursing Care Service Ward)

  • 심송미;김은하
    • 한국보건간호학회지
    • /
    • 제33권2호
    • /
    • pp.200-213
    • /
    • 2019
  • Purpose: This study was conducted to examine the effect of a fall prevention education on the fall related knowledge and fall prevention behavior of the elderly patients in comprehensive nursing care service wards. Method: A quasi experimental study with control group and experimental group was used. A total 62 elderly patients in comprehensive nursing care service wards were randomly divided into the experimental group(n=30) and the control group(n=32). The data collection period was from August to December, 2017. Data were analyzed with $X^2-test$, paired t-test, independent t-test and Pearson's correlation coefficient by using SPSS 25.0. Results: Experimental group reported higher score in fall related knowledge than the control group(t=-10.28, p<.001). Participants who viewed DVD and received the leaflet education reported higher score than those with routine admission education(t=-6.51, p<.001). The experimental group showed significant improvement in fall related knowledge and fall prevention behavior(r=.21, p=.015). Conclusion: The fall prevention program was effective in improving fall-related knowledge and fall prevention behavior among elderly patients. Since the DVD plus leaflet education was effective in improving prevention behaviors, it might be included in routine orientation on admission for the elderly patient in comprehensive nursing care service wards.