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The Role of Double Inversion Recovery Imaging in Acute Ischemic Stroke

  • Choi, Na Young;Park, Soonchan;Lee, Chung Min;Ryu, Chang-Woo;Jahng, Geon-Ho
    • Investigative Magnetic Resonance Imaging
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    • v.23 no.3
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    • pp.210-219
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    • 2019
  • Purpose: The purpose of this study was to investigate if double inversion recovery (DIR) imaging can have a role in the evaluation of brain ischemia, compared with diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) imaging. Materials and Methods: Sixty-seven patients within 48 hours of onset, underwent MRI scans with FLAIR, DWI with b-value of 0 (B0) and $1000s/mm^2$, and DIR sequences. Patients were categorized into four groups: within three hours, three to six hours, six to 24 hours, and 24 to 48 hours after onset. Lesion-to-normal ratio (LNR) value was calculated and compared among all sequences within each group, by the Friedman test and conducted among all groups, for each sequence by the Kruskal-Wallis test. In qualitative assessment, signal intensity changes of DIR, B0, and FLAIR based on similarity with DWI and image quality of each sequence, were graded on a 3-point scale, respectively. Scores for detectability of lesions were compared by the McNemar's test. Results: LNR values from DWI were higher than DIR, but not statistically significant in all groups (P > 0.05). LNR values of DIR were significantly higher than FLAIR within 24 hours of onset (P < 0.05). LNR values were significantly different between, before, and after six hours onset time for DIR (P = 0.016), B0 (P = 0.008), and FLAIR (P = 0.018) but not for DWI (P = 0.051). Qualitative analysis demonstrated that detectability of DIR was higher, compared to that of FLAIR within 4.5 hours and six hours of onset (P < 0.05). Also, the DWI quality score was lower than that of DIR, particularly relative to infratentorial lesions. Conclusion: DIR provides higher detectability of hyperacute brain ischemia than B0 and FLAIR, and does not suffer from susceptibility artifact, unlike DWI. So, DIR can be used to replace evaluation of the FLAIR-DWI mismatch.

Assessment of Diffusion-Weighted Imaging-FLAIR Mismatch: Comparison between Conventional FLAIR versus Shorter-Repetition-Time FLAIR at 3T

  • Goh, Byeong Ho;Kim, Eung Yeop
    • Investigative Magnetic Resonance Imaging
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    • v.20 no.2
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    • pp.88-94
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    • 2016
  • Purpose: Fluid-attenuated inversion recovery (FLAIR) imaging can be obtained faster with shorter repletion time (TR), but it gets noisier. We hypothesized that shorter-TR FLAIR obtained at 3 tesla (3T) with a 32-channel coil may be comparable to conventional FLAIR. The aim of this study was to compare the diagnostic value between conventional FLAIR (TR = 9000 ms, FLAIR9000) and shorter-TR FLAIR (TR = 6000 ms, FLAIR6000) at 3T in terms of diffusion-weighted imaging-FLAIR mismatch. Materials and Methods: We recruited 184 patients with acute ischemic stroke (28 patients < 4.5 hours) who had undergone 5-mm diffusion-weighted imaging (DWI) and two successive 5-mm FLAIR images (no gap; in-plane resolution, $0.9{\times}0.9mm$) at 3T with a 32-channel coil. The acquisition times for FLAIR9000 and FLAIR6000 were 108 seconds (generalized autocalibrating partially parallel acquisitions [GRAPPA] = 2) and 60 seconds (GRAPPA = 3), respectively. Two radiologists independently assessed the paired imaging sets (DWI-FLAIR9000 and DWI-FLAIR6000) for the presence of matched hyperintense lesions on each FLAIR imaging. The signal intensity ratios (area of DWI lesion to contralateral normal-appearing region) on both FLAIR imaging sets were compared. Results: DWI-FLAIR9000 mismatch was present in 39 of 184 (21.2%) patients, which was perfectly the same on FLAIR6000. Three of 145 patients (2%) with DWI-matched lesions on FLAIR9000 had discrepancy on FLAIR6000, showing no significant difference (P > 0.05). Interobserver agreement was excellent for both DWI-FLAIR9000 and DWI-FLAIR6000 (k = 0.904 and 0.883, respectively). Between the two FLAIR imaging sets, there was no significant difference of signal intensity ratio (mean, standard deviation; $1.25{\pm}0.20$; $1.24{\pm}0.20$, respectively) (P > 0.05). Conclusion: For the determination of mismatch or match between DWI and FLAIR imaging, there is no significant difference between FLAIR9000 and FLAIR6000 at 3T with a 32-channel coil.

Field experiment of ERT to detect a tunnel (터널 탐지를 위한 전기비저항 토모그래피 응용 실험)

  • Yi, Myeong-Jong;Kim, Jung-Ho;Cho, Seong-Jun;Kobayashi, Takao
    • 한국지구물리탐사학회:학술대회논문집
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    • 2007.06a
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    • pp.215-218
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    • 2007
  • Tunnel detection is known to be one of the challenging problems in geophysical society. Among various geophysical methods, we tried to examine the applicability of electrical resistivity tomography (ERT) method to detect empty tunnel. In this study, we analyzed the ERT data acquired at the test site for tunnel detection. The inversion results have shown reasonable image of the tunnel although the resolution is quite poor. Moreover, we could obtain the three-dimensional attitude of tunnel through 3-D ERT imaging. Therefore, we expect that ERT can make contribution to the tunnel detection problem and further research effort such as fusion of geophysical methods will provide more reliable tunnel detection capability.

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T1-weighted MR Imaging of the Neonatal Brain at 3.0 Tesla: Comparison of Spin Echo, Fast Inversion Recovery, and Magnetization-prepared Three Dimensional Gradient Echo Techniques (3T 자기공명영상 장비에서 신생아 뇌의 T1 강조 영상: 스핀에코, 고속 역전회복, 자기화 삼차원 경사에코기법의 비교)

  • Jeong, Jee-Young;Yoo, So-Young;Jang, Kyung-Mi;Eo, Hong;Lee, Jung-Hee;Kim, Ji-Hye
    • Investigative Magnetic Resonance Imaging
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    • v.11 no.2
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    • pp.87-94
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    • 2007
  • Purpose: The purpose of this study was to evaluate the usefulness of fast inversion recovery (FIR) and magnetization-prepared three dimensional gradient echo sequence (3D GRE) T1-weighted sequences for neonatal brain imaging compared with spin echo (SE) sequence in a 3T MR unit. Materials and Methods: T1-weighted axial SE, FIR and 3D GRE sequences were evaluated from 3T brain MR imaging in 20 neonates. The signal-to-noise ratio (SNR) of different tissues was measured and contrast-to-noise ratios (CNR) were determined and compared in each of the sequences. Visual analysis was carried out by grading gray-white matter differentiation, myelination, and artifacts. The Wilcoxon signed ranked test was used for evaluation of the statistical significance of CNR differences between the sequences. Results: Among the three sequences, the 3D GRE had the best SNRs. CNRs obtained with FIR and 3D GRE were statistically superior to those obtained with SE; these CNRs were better on the 3D GRE compared to the FIR. Gray to white matter differentiation and myelination were better delineated on the FIR and 3D GRE than the SE. However, motion artifacts were more commonly observed on the 3D GRE and flow-related artifacts of vessels were frequently seen on the FIR. Conclusion: FIR and 3D GRE are valuable alternative T1-weighted sequences to conventional SE imaging of the neonatal brain at 3T providing superior image quality.

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Development of membrane blend using casting technique for water desalination

  • El-Gendi, A.;Ali, S.S.;Ahmed, S.A.;Talaat, H.A.
    • Membrane and Water Treatment
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    • v.3 no.3
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    • pp.201-209
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    • 2012
  • Membrane separation technologies have some of advantages are considered a better alternative to traditional methods. Research of novel membranes is very vital for covering the higher required of membrane in several purposes like water desalting technology. In this work polyamide-6/cellulose acetate (PA-6/CA) blend membrane was developed according to the wet phase inversion system. The structures of the prepared membranes were examined by scanning electron microscopy (SEM). SEM images showed uniform particles distribution in the prepared membranes. Moreover, SEM images revealed that the membranes have relatively uniform surface (PA-6/CA). PA-6/CA blend membranes systems are evaluated by using synthetic NaCl solution. The separation performance showed that salt rejection increased with increasing of heat treatment of the casted films and it was improved with increasing of operating pressure.

The Effect of Incidence of Ankle Sprains on Both Leg Length Inequalities and Range of Motion of Ankle Joint in 20's Female University Students (20대 여대생의 양다리길이차이 및 발목관절가동범위가 발목 염좌 발생률에 미치는 영향)

  • Park, Jong-Hang;Jeong, Yeon-Woo;Kim, Tae-won
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.21 no.1
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    • pp.29-35
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    • 2015
  • Background: The purpose of this study was conducted to investigate the effect of incidence of ankle sprains on both leg length inequalities and range of motion of ankle joint in 20's female university students. Methods: 20's female university students were targeting 32 people attending K university in Gwangju. Both leg length inequality was measured using a tape measure, ranges of motion of ankles was measured using a goniometer. Results: The ankle sprain incidence was quite high, with 56.25% (n=18) for the right ankle, 34.38% (n=11) for the left ankle, and 9.38% (n=3) for both. As for the difference between the ankle sprain incidence and both leg length, the average value of the right leg was $83.08{\pm}3.69$, the average value of the left leg was $84.28{\pm}3.27$, making the right leg shorter than the left by 1.2cm with a higher incidence and showing a positive statistical correlation between the two (p<.05). Also showed that there was a negative statistical correlation between ankle sprain incidences and the inversion range of motion spread of the right ankle (p<.05). Conclusion: The incidence of ankle sprains was higher for the larger the difference between both leg length inequality. In addition, the smaller the inversion range of motion spread of the right ankle, the higher the incidence of ankle sprains. Therefore, The evidence suggests that the incidence of ankle sprains can be reduced by recommending stability and efficient exercises that take into consideration the both leg length as well as the ranges of motion of ankle joints.

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Controlling the Morphology of Polyvinylidene-co-hexafluoropropylene (PVDF-co-HFP) Membranes Via Phase Inversion Method (상전이법을 이용한 P(VDF-co-HFP) 분리막 구조제어)

  • Song, Ye Jin;Kim, Jong Hoo;Kim, Ye Som;Kim, Sang Deuk;Cho, Young Hoon;Park, Ho Sik;Nam, Seung Eun;Park, You In;Son, Eun Ho;Kim, Jeong F.
    • Membrane Journal
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    • v.28 no.3
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    • pp.187-195
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    • 2018
  • In this work, the morphology of polyvinylidene-co-hexafluoropropylene (PVDF-co-HFP) membranes were systemically investigated using phase inversion technique, to target membrane contactor applications. As the presence of macrovoids degrade the mechanical integrity of the membranes and jeopardize the long-term stability of membrane contactor processes (e.g. wetting), a wide range of dope compositions and casting conditions was studied to eliminate the undesired macrovoids. The type of solvent had significant effect on the membrane morphology, and the observed morphology were correlated to the physical properties of the solvent and solvent-polymer interactions. In addition, to fabricate macrovoid-free structure, the effects of different coagulation temperatures, inclusion of additives, and addition of nonsolvents were investigated. Due to the slow crystallization rate of P(VDF-co-HFP) polymer, it was found that obtaining porous membrane without macrovoids is difficult using only nonsolvent-induced phase separation method (NIPS). However, combined other phase inversion methods such as evaporation-induced phase separation (EIPS) and vapor-induced phase separation (VIPS), the desired membrane morphology can be obtained without any macrovoids.

Sub-surface imaging and vector precision from high resolution down-hole TEM logging

  • Chull, James;Massie, Duncan
    • 한국지구물리탐사학회:학술대회논문집
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    • 2005.09a
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    • pp.11-18
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    • 2005
  • Filament inversion routines are highly effective for target definition whenever total-field DHTEM vectors can be obtained using three-component logging tools. However most cross-hole components contain significant noise related to sensor design and errors in observation of probe rotation. Standard stacking methods can be used to improve data quality but additional statistical methods based on cross-correlation and spatial averaging of orthogonal components may be required to ensure a consistent vector migration path. Apart from assisting with spatial averaging, multiple filaments generated for successive time-windows can provide additional imaging information relating to target geometry and current migration. New digital receiver systems provide additional time-windows to provide better tracking options necessary for high-resolution imaging of this type.

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The association between T wave inversion and apical hypertrophic cardiomyopathy

  • Chae, Cheol Byoung;Ha, Ju Hee;Kim, Jun Ho;Lee, Jae Joon;Choi, Han Il;Park, Ki Beom;Kim, Jin Hee;Choi, Jung Hyun
    • Kosin Medical Journal
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    • v.33 no.3
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    • pp.328-336
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    • 2018
  • Objectives: Electrocardiograhy (ECG) is the first step in hypertrophic cardiomyopathy (HCMP) diagnosis. For various reasons, the T wave inversion (TWI) and ECG change with time and HCMP is not easy to diagnosis. The aim of this retrospective study was to investigate the association between TWI on ECG and apical HCMP. Methods: A total of 4,730 ECGs presenting TWI from January 2011 to March 2013 in Pusan National University Hospital were enrolled. 133 patients who were examined by both echocardiography and coronary angiogram were analyzed. Patients were divided into two groups: Group A (TWI ${\geq}$ 10 mm) and Group B (5 mm ${\leq}$ TWI < 10 mm). HCMP is defined by a wall thickness ${\geq}15mm$ in one or more LV myocardial segments. Apical HCMP is defined to be hypertrophy that is confined to LV apex. The patients who had ECGs with at least one month interval were divided 3 groups: Normal T wave, Abnormal T wave, and Persistent TWI. The prevalence of Apical HCMP and coronary artery disease (CAD) was reviewed among the three groups. Results: In this study there were a total 133 patients, with patients divided into Group A which had 15 patients and Group B which had 118 patients. Among the 23 patients with apical HCMP, three patients were Group A and twenty patients were Group B (P = 0.769). Regarding constancy of TWI, persistent TWI group was higher in apical HCMP than in other groups (P = 0.038). CAD had no difference between groups (P = 0.889). Conclusions: T wave negativity was not associated with incidence of apical HCMP. However, apical HCMP was diagnosed more frequently in patients with persistent TWI. Further follow up echocardiographic study is needed to evaluate the progression of apical HCMP in patients with TWI.

Performance Test of Hypocenter Determination Methods under the Assumption of Inaccurate Velocity Models: A case of surface microseismic monitoring (부정확한 속도 모델을 가정한 진원 결정 방법의 성능평가: 지표면 미소지진 모니터링 사례)

  • Woo, Jeong-Ung;Rhie, Junkee;Kang, Tae-Seob
    • Geophysics and Geophysical Exploration
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    • v.19 no.1
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    • pp.1-10
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    • 2016
  • The hypocenter distribution of microseismic events generated by hydraulic fracturing for shale gas development provides essential information for understanding characteristics of fracture network. In this study, we evaluate how inaccurate velocity models influence the inversion results of two widely used location programs, hypoellipse and hypoDD, which are developed based on an iterative linear inversion. We assume that 98 stations are densely located inside the circle with a radius of 4 km and 5 artificial hypocenter sets (S0 ~ S4) are located from the center of the network to the south with 1 km interval. Each hypocenter set contains 25 events placed on the plane. To quantify accuracies of the inversion results, we defined 6 parameters: difference between average hypocenters of assumed and inverted locations, $d_1$; ratio of assumed and inverted areas estimated by hypocenters, r; difference between dip of the reference plane and the best fitting plane for determined hypocenters, ${\theta}$; difference between strike of the reference plane and the best fitting plane for determined hypocenters, ${\phi}$; root-mean-square distance between hypocenters and the best fitting plane, $d_2$; root-mean-square error in horizontal direction on the best fitting plane, $d_3$. Synthetic travel times are calculated for the reference model having 1D layered structure and the inaccurate velocity model for the inversion is constructed by using normal distribution with standard deviations of 0.1, 0.2, and 0.3 km/s, respectively, with respect to the reference model. The parameters $d_1$, r, ${\theta}$, and $d_2$ show positive correlation with the level of velocity perturbations, but the others are not sensitive to the perturbations except S4, which is located at the outer boundary of the network. In cases of S0, S1, S2, and S3, hypoellipse and hypoDD provide similar results for $d_1$. However, for other parameters, hypoDD shows much better results and errors of locations can be reduced by about several meters regardless of the level of perturbations. In light of the purpose to understand the characteristics of hydraulic fracturing, $1{\sigma}$ error of velocity structure should be under 0.2 km/s in hypoellipse and 0.3 km/s in hypoDD.