• 제목/요약/키워드: metabolic sensors

검색결과 12건 처리시간 0.015초

세포대사 기능 분석을 위한 광학센서 기반 용존산소와 pH 측정 시스템의 제작 및 특성 분석 (Characteristics and Fabrication of Dissolved Oxygen and pH Measurement System based on the Optical Sensor for Analysis of Cell Metabolic Functions)

  • 장지운;황인숙;이종목;이선민;강소라;김영미;김나영
    • 센서학회지
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    • 제25권1호
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    • pp.51-56
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    • 2016
  • This study evaluates the performance of an optical sensor and measurement system (CMA-24) which can analyze the fluctuation of dissolved oxygen and pH simultaneously. In the optical sensor system, the fluorescent materials, Rudpp and HPTS which are sensitive to dissolved oxygen and pH, respectively, are coated on the bottom of a 24-well -plate by the sol-gel technology. The detection times of the emission light of the oxygen sensor were $4,186{\pm}13.90{\mu}s$ and $4,452{\pm}36.68{\mu}s$ for the dissolved oxygen of 17% $O_2$ and 7.6% $O_2$, respectively. On the other hand, the detection times of the pH sensor were $6,699.43{\pm}14.64{\mu}s$, $6,722.24{\pm}6.21{\mu}s$, and $6,748.52{\pm}2.63{\mu}s$ using pH 6, 7, and 8, respectively. When we determined cellular respiration levels of C2C12 myocytes with CMA-24, $O_2$/pH measurement system, the ratio of the uncoupled to coupled OCR (oxygen consumption rate) was 1.41. The results mean that this CMA-24 system shows almost the same sensitiveness as the commercial system.

압전 필름과 전도성 섬유를 이용한 맥파 전달 속도 측정을 위한 센서의 제작 및 성능평가 (Fabrication and Evaluation of Sensor for Measuring Pulse Wave Velocity using Piezo Film and Conductive Textile)

  • 김정채;지선하;유선국
    • 센서학회지
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    • 제21권2호
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    • pp.135-143
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    • 2012
  • Arterial stiffness is causing the serious problems for human who is suffered from hypertension and metabolic syndrome. So it is important that measure the arterial stiffness for early prevention. Many researches point out that pulse wave velocity(PWV) is the reliable and simple method to predict arterial stiffness. In this paper, we developed the sensing parts that detect the pulse wave and ECG by using piezoelectric film and conductive textile with elastic band. Our system could detect 3ch pulse wave and ECG. Simultaneously, our algorithm extracts the features for calculating the delays among pulse waves. The delays are the significant parameter to estimate PWV, thus we design the experiment for evaluating the performance of our sensing parts. The reference is PP-1000(HanByul Meditech, Korea) that is good for performance evaluation. As a result, the start point of the pulse wave was the most reliable feature for comparing with PP-1000(r=0.691, P=0.00). The results between two operators showed that there is only a slight difference in the reproducibility of the devices. In conclusion, we assume that the suggested sensor could be more comfortable and faithful method for arterial stiffness.