• 제목/요약/키워드: meta-synthesis

검색결과 112건 처리시간 0.031초

Firefighting and Cancer: A Meta-analysis of Cohort Studies in the Context of Cancer Hazard Identification

  • Nathan L. DeBono;Robert D. Daniels ;Laura E. Beane Freeman ;Judith M. Graber ;Johnni Hansen ;Lauren R. Teras ;Tim Driscoll ;Kristina Kjaerheim;Paul A. Demers ;Deborah C. Glass;David Kriebel;Tracy L. Kirkham;Roland Wedekind;Adalberto M. Filho;Leslie Stayner ;Mary K. Schubauer-Berigan
    • Safety and Health at Work
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    • 제14권2호
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    • pp.141-152
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    • 2023
  • Objective: We performed a meta-analysis of epidemiological results for the association between occupational exposure as a firefighter and cancer as part of the broader evidence synthesis work of the IARC Monographs program. Methods: A systematic literature search was conducted to identify cohort studies of firefighters followed for cancer incidence and mortality. Studies were evaluated for the influence of key biases on results. Random-effects meta-analysis models were used to estimate the association between ever-employment and duration of employment as a firefighter and risk of 12 selected cancers. The impact of bias was explored in sensitivity analyses. Results: Among the 16 included cancer incidence studies, the estimated meta-rate ratio, 95% confidence interval (CI), and heterogeneity statistic (I2) for ever-employment as a career firefighter compared mostly to general populations were 1.58 (1.14-2.20, 8%) for mesothelioma, 1.16 (1.08-1.26, 0%) for bladder cancer, 1.21 (1.12-1.32, 81%) for prostate cancer, 1.37 (1.03-1.82, 56%) for testicular cancer, 1.19 (1.07-1.32, 37%) for colon cancer, 1.36 (1.15-1.62, 83%) for melanoma, 1.12 (1.01-1.25, 0%) for non-Hodgkin lymphoma, 1.28 (1.02-1.61, 40%) for thyroid cancer, and 1.09 (0.92-1.29, 55%) for kidney cancer. Ever-employment as a firefighter was not positively associated with lung, nervous system, or stomach cancer. Results for mesothelioma and bladder cancer exhibited low heterogeneity and were largely robust across sensitivity analyses. Conclusions: There is epidemiological evidence to support a causal relationship between occupational exposure as a firefighter and certain cancers. Challenges persist in the body of evidence related to the quality of exposure assessment, confounding, and medical surveillance bias.

초·중등학교 피지컬 컴퓨팅 교육 연구의 메타 종합 분석 (A Meta-Synthesis of Research about Physical Computing Education in Korean Elementary and Secondary Schools)

  • 이은경
    • 컴퓨터교육학회논문지
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    • 제22권5호
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    • pp.1-9
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    • 2019
  • 최근 소프트웨어 교육 강화 정책 및 2015 개정 교육과정을 통해 피지컬 컴퓨팅 교육이 활발히 추진되고 있다. 피지컬 컴퓨팅 교육은 컴퓨팅 사고력, 창의성, 협력적 문제해결력 향상 등을 위해 유의미한 학습 활동임에도 불구하고 매우 복잡하고 융합적 학습 활동이라는 측면에서 실제 학교 현장의 수업 적용 시 많은 어려움이 따른다. 이를 지원하기 위한 다양한 연구들의 추진되어 왔으며, 본 연구에서는 그 간 추진되어 온 초 중등학교 피지컬 컴퓨팅 교육 연구들을 종합적으로 분석하고 학교 현장에서의 어려움을 해결하기 위한 향후 연구 추진 방향에 관해 논의하고자 하였다. 본 연구에서는 우리나라 초 중등학교에서의 피지컬 컴퓨팅 교육의 추진 현황, 방법, 효과성 등에 관한 양적, 질적 연구들을 종합적으로 분석하기 위해 메타 종합 분석 연구를 사용하였으며, 연구 결과, 피지컬 컴퓨팅 교육의 목적, 교수 학습 방법, 도구들의 활용 현황을 파악하고 이에 따른 교육 효과들을 확인하였다.

국제 STEM 교육 연구에서의 이슈: 메타 종합적 접근 (Issues in Research of Global STEM Education: A Meta Synthesis Approach)

  • 권혁수;박병열
    • 과학교육연구지
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    • 제45권1호
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    • pp.11-22
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    • 2021
  • 이 연구의 목적은 국제 STEM 교육 분야의 연구 결과를 종합하여 국제 STEM 교육의 주요 이슈를 파악하는 데 있다. 이 연구의 분석 대상 자료는 선정 기준과 전문가 그룹의 검토를 통해 다양한 STEM 교육의 이슈를 반영하고 있는 메타분석 또는 체계적 문헌연구의 결과이다. 총 23개의 연구를 대상으로 질적 메타 분석을 하여 다음과 같은 STEM 교육의 이슈를 선정하였다. 첫째, STEM 교육은 국제적인 교육 동향으로 미국, 캐나다, 호주, 한국, 터키 등 많은 국가에서 연구되고 있다. 둘째, STEM 교육은 학생들의 인지적, 정의적, 심동적, 그리고 진로 영역의 향상에 긍정적으로 기여하고 있다. 셋째, STEM 교육은 다양한 수업 도구와 기술의 사용과 함께 연구되어 왔다. 또한, STEM 교육에 대한 교사의 전문성 신장이 성공적인 STEM 교육의 실현의 주요 요인들 중 하나이다. 그 외에 STEM 교육의 성공적인 실천을 위해 다양성, 평등, 타당하고 신뢰로운 연구 설계 등의 이슈에 대해 논의하였다. 또한 이 연구는 우리나라 융합교육의 방향과 실천 전략을 위한 함의점을 제공할 수 있으며 향후 연구에 대한 제언을 줄 수 있다.

The role of percutaneous neurolysis in lumbar disc herniation: systematic review and meta-analysis

  • Manchikanti, Laxmaiah;Knezevic, Emilija;Knezevic, Nebojsa Nick;Sanapati, Mahendra R.;Kaye, Alan D.;Thota, Srinivasa;Hirsch, Joshua A.
    • The Korean Journal of Pain
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    • 제34권3호
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    • pp.346-368
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    • 2021
  • Background: Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases, percutaneous neurolysis with targeted delivery of medications is often the next step in pain management. Methods: An evidence-based system of methodologic assessment, namely, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was used. Multiple databases were searched from 1966 to January 2021. Principles of the best evidence synthesis were incorporated into qualitative evidence synthesis. The primary outcome measure was the proportion of patients with significant pain relief and functional improvement (≥ 50%). Duration of relief was categorized as short-term (< 6 months) and long-term (≥ 6 months). Results: This assessment identified one high-quality randomized controlled trial (RCT) and 5 moderate-quality non-randomized studies with an application of percutaneous neurolysis in disc herniation. Overall, the results were positive, with level II evidence. Conclusions: Based on the present systematic review, with one RCT and 5 non-randomized studies, the evidence level is II for percutaneous neurolysis in managing lumbar disc herniation.

Synthesis and Herbicidal Activities of N-Phenyl Oxadiazolidinedione Derivatives

  • Kim, Hyung-Jin;Hwang, Kwang-Jin;Park, Chong-Hoe;Lee, Jae-Hyun
    • Bulletin of the Korean Chemical Society
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    • 제14권6호
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    • pp.717-722
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    • 1993
  • N-Phenyl oxadiazolidinedione derivatives II were synthesized and their herbicidal activities were measured against grass weeds. A parabolic relationship between molar refractivity (MR) of meta substituents of dione Ⅱ and their herbicidal activities was observed. With the substituents having MR value=${\sim}15$, the higher activities were obtained. Especially, the highest herbicidal activity (97% inhibition of weeds at 0.25 kg/ha) was observed by propyne IIr containing propargyloxy group as meta substituent.

사회복지사의 클라이언트 폭력경험과 대처에 관한 질적 해석적 메타통합(QIMS) 연구 (A Qualitative Interpretative Meta-Synthesis(QIMS) Study on the Experience and Coping of Client Violence in Social Workers)

  • 길태영
    • 한국콘텐츠학회논문지
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    • 제21권10호
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    • pp.738-752
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    • 2021
  • 본 연구는 사회복지사의 클라이언트 폭력경험과 대처를 보다 새롭고 깊이 있게 탐색하고자 최근 사회과학분야에 새롭게 소개된 QIMS(Qualitative Interpretive Meta Synthesis)를 적용하였다. 그동안 우리나라에서 발표된 질적 개별연구 결과물에 대한 통합적인 분석으로 기존 연구결과의 축적된 지식과 시너지적 이해경로로 풍성한 결과를 도출하였고, 질적 연구가 갖는 한계를 극복할 수 있었다. 2013년부터 2020년까지 발표된 8편을 최종분석에 포함하였고, 총 85명의 사회복지사가 진술한 내용을 분석하였다. 자료범위 축소 및 주제 추출과 통합의 반복과정을 통해 새롭고 중요하게 생성된 주제는 (1) 떼어낼 수 없는 폭력과 고통, (2) 직업의 결과로 경험한 이중성, (3) 지속적인 변화 시도, (4) 사명감의 발현과 직업 의미부여 총 4개의 범주로 구분되었다. 통합된 주제들로부터 이끌어낸 결과를 바탕으로 다양한 실천현장에서 사회복지사가 경험하는 클라이언트 폭력예방과 대처를 위한 실천적·정책적 대안을 제시하였다.

집중치료 후 증후군 경험에 관한 질적 통합 연구 (Post-Intensive Care Syndrome Experience among Critical Care Survivors: A Meta-synthesis of Qualitative Research)

  • 강지연;정연진;윤선영;이민주;백민정;신소영;홍희진;김수경;조영신
    • 중환자간호학회지
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    • 제10권1호
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    • pp.13-30
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    • 2017
  • Purpose: The purpose of this study was to integrate the results of qualitative studies to understand critical care survivors' experience of the post-intensive care syndrome (PICS). Methods: This was a meta-synthesis of primary studies that used qualitative methods. We reviewed 26 qualitative studies on PICS selected from 8 international and Korean databases and from a manual search. Thomas and Harden's 3 stages (free coding, development of descriptive themes, generation of analytical themes) for thematic synthesis were utilized to analyze the collected qualitative data. Results: Four descriptive themes emerged from the thematic synthesis: weak physical conditions, psycho-emotional changes, the painful-memory of intensive care units, and social vulnerability. The analytical theme for the current study was "unfamiliarity with the vulnerable self." Critical care survivors had to confront entirely different "selves" after discharge from intensive care units. They had become physically weak, psychologically unstable, and the critical memories continued to create distress. These changes increased their social vulnerability by making them dependent on others, causing family conflicts, and changing interpersonal relationships. Conclusions: Finding from this qualitative synthesis and other related literature highlight the severity of PICS and the importance of rehabilitative intervention for critical care survivors.

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Facile Synthesis and Characterization of Poly(dialkoxy-p-phenylene 1,3,4-oxadiazole-alt-phenylene 1,3,4-oxadiazole)s

  • Kim, Hoon-Seok;Kang, Soon-Min;Do, Jung-Yun
    • Macromolecular Research
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    • 제16권4호
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    • pp.360-366
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    • 2008
  • Poly(dialkoxyphenylene 1,3,4-oxadiazole)s were conveniently synthesized to compare their material properties of solvent solubility, thermal stability and molecular alignment with respect to alkyl chain length and meta/para-phenylene structure. All prepared polymers exhibited good solubility in co-solvents containing various volume levels of chloroform to trifluoroacetic acid. Meta-polymers showed slightly better solubility than para-polymers. All polymers produced were thermally stable up to $320^{\circ}C$. Photoluminescence of polymer films was observed with blue light emission at around 450 nm. X-ray diffraction patterns of all polymers indicated that they were composed of stacked molecular sheets with the same layer-to-layer distance of $3.4\;{\AA}$. However, side chain-to-side chain and main chain-to-main distances within the layers increased with increasing alkyl chain lengths. The meta-polymer chains were separated more than the para-polymer chains.

국내 암환자와 관련된 연구논문의 메타분석 - 실험연구를 중심으로 - (An Integrative Review and Meta-analysis of Oncology Nursing Research : 1985-1997.2)

  • 임선옥;홍은영
    • 대한간호학회지
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    • 제27권4호
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    • pp.857-870
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    • 1997
  • The purposes of this study were to describe 12 years of patient-related oncology nursing research in Korea, identifying various nursing interventions, and assesing the effectiveness of the interventions, through analysis and synthesis of the accumulated research papers. One hundred and seventy-nine studies were selected for this study and these were mostly descriptive in design (69.2%). Of the 179 studies, 25 met the criteria for meta-analytic treatment. Twenty-five experimental studies were found in theses and dissertations (68%), 92% used convenience sample, and the median sample size was 40. Subjects were predominantly in treatment and rehabilitation (76%). Most studies(68%) were not derived from a theory base, with only 8% reporting use of a nursing theory. Results of the meta-analysis are as follows. The effect size of the nursing intervention type was found to be significantly effective. The standardized mean difference ranged from a high positive of 2.55 to a low negative of -0.22. Direct personal nursing intervention method was more effective than indirect group method. Two nursing intervention methods were more effective than one. The greatest effect size was thyxical intervention. The greatest mean effect size was scalp hypothermia technique. Teaching was a frequent intervention after 1990, although a wide range of treatments were studied. Effect size of intervention for symptom management was largest in relieving pain. Effective intervention method for relieving anxiety was exercise.

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전자상거래 연구에서 인지된 가치의 선행 요인에 관한 메타분석 (A Meta-Analysis of External Factors on Perceived Value in E-commerce)

  • 남수태;진찬용
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2016년도 춘계학술대회
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    • pp.112-114
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    • 2016
  • 데이터 분석은 기존 데이터베이스 관리 도구로부터 데이터를 수집, 저장, 관리, 분석할 수 있는 역량을 말한다. 또한, 대량의 정형 또는 비정형 데이터 집합으로부터 가치를 추출하고 결과를 분석하는 기술을 의미한다. 따라서 메타분석은 여러 실증연구의 정량적인 결과를 통합과 분석을 통해 전체 결과를 조망할 수 있는 기회를 제공하는 통계적 통합 방법이다. 전자상거래 연구에서 인지된 가치의 선행 외부요인들은 연구자에 따라서 다양하게 적용하여 연구되어오고 있다. 본 연구에서는 국내 주요 학회지에 게재된 인지된 가치 관련연구에서 어떠한 요인들을 사용하고 있고 또한 이러한 외부요인들이 인지된 가치 어느 정도의 설명력을 가지는지를 메타분석을 통해 알아보고자 한다. 따라서 연구결과를 바탕으로 학문적 실무적 의의를 논의하고자 한다.

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