• 문화기술의 융합
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• 제8권6호
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• pp.389-395
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• 2022

본 연구는 성인대학생의 핵심역량모형을 개발하는 것을 목적으로 한다. 이를 위해 국내외 문헌연구를 분석하여 성인대학생의 핵심역량을 도출하였으며, 핵심역량의 타당성을 위하여 델파이 조사를 하였다. 이를 위해 SPSS 18.0 프로그램을 이용하여 분석하였다. 연구결과는 의사소통, 문제해결 및 메타, 대인관계, 자기관리·개발, 디지털 정보 문해, 전공지식, 시민의식, 융합, 인성, 전문직업과 글로벌로 총 11개의 성인대학생 핵심역량이 도출되었다. 성인대학생의 핵심역량모형은 델파이 조사의 결과를 바탕으로 01~11의 번호를 부여하여 개발하였다. 성인대학생의 핵심역량은 서로 유기적으로 연계되어 있어 하나의 핵심역량의 함양은 다른 핵심역량에도 영향을 미치는 것으로 나타났다.

• 대한약침학회지
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• 제25권4호
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• pp.326-343
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• 2022

Neurological disorders represent a substantial healthcare burden worldwide due to population aging. Acorus gramineus Solander (AG) and Acorus tatarinowii Schott (AT), whose major component is asarone, have been shown to be effective in neurological disorders. This review summarized current information from preclinical and clinical studies regarding the effects of extracts and active components of AG and AT (e.g., α-asarone and β-asarone) on neurological disorders and biomedical targets, as well as the mechanisms involved. Databases, including PubMed, Embase, and RISS, were searched using the following keywords: asarone, AG, AT, and neurological disorders, including Alzheimer's disease, Parkinson's disease, depression and anxiety, epilepsy, and stroke. Meta-analyses and reviews were excluded. A total of 873 studies were collected. A total of 89 studies were selected after eliminating studies that did not meet the inclusion criteria. Research on neurological disorders widely reported that extracts or active components of AG and AT showed therapeutic efficacy in treating neurological disorders. These components also possessed a wide array of neuroprotective effects, including reduction of pathogenic protein aggregates, antiapoptotic activity, modulation of autophagy, anti-inflammatory and antioxidant activities, regulation of neurotransmitters, activation of neurogenesis, and stimulation of neurotrophic factors. Most of the included studies were preclinical studies that used in vitro and in vivo models, and only a few clinical studies have been performed. Therefore, this review summarizes the current knowledge on AG and AT therapeutic effects as a basis for further clinical studies, and clinical trials are required before these findings can be applied to human neurological disorders.

• Journal of Microbiology and Biotechnology
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• 제33권7호
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• pp.875-885
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• 2023

Volatile organic compounds such as benzene, toluene, ethylbenzene, and isomers of xylenes (BTEX) constitute a group of monoaromatic compounds that are found in petroleum and have been classified as priority pollutants. In this study, based on its newly sequenced genome, we reclassified the previously identified BTEX-degrading thermotolerant strain Ralstonia sp. PHS1 as Cupriavidus cauae PHS1. Also presented are the complete genome sequence of C. cauae PHS1, its annotation, species delineation, and a comparative analysis of the BTEX-degrading gene cluster. Moreover, we cloned and characterized the BTEX-degrading pathway genes in C. cauae PHS1, the BTEX-degrading gene cluster of which consists of two monooxygenases and meta-cleavage genes. A genome-wide investigation of the PHS1 coding sequence and the experimentally confirmed regioselectivity of the toluene monooxygenases and catechol 2,3-dioxygenase allowed us to reconstruct the BTEX degradation pathway. The degradation of BTEX begins with aromatic ring hydroxylation, followed by ring cleavage, and eventually enters the core carbon metabolism. The information provided here on the genome and BTEX-degrading pathway of the thermotolerant strain C. cauae PHS1 could be useful in constructing an efficient production host.

• 융합신호처리학회논문지
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• 제23권2호
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• pp.91-96
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• 2022

현재 카메라 기반 기술 수준으로는 센서 기반 기본 생활패턴 인지 기술은 정확한 데이터를 얻기 위해서는 불편함을 감수해야 하고, 상용화 밴드 제품은 정확한 데이터 수집이 어려우며, 행동의 동기와 원인 및 심리적 영향 등을 고려하지 못하는 실정이다. 본 논문에서는 생활패턴 인지를 위한 레이더 기술은 일상생활에서 주변의 사람이나 물체를 탐지하기 위해 고안된 파형을 전송하여 반사되어 오는 수신 신호를 신호 처리함으로써 물체와의 거리, 속도, 각도를 측정하는 기술을 적용하여 기존 영상 기반의 서비스에서의 사생활 보호와 같은 이슈를 보완할 수 있도록 고안하였다. 제안 시스템의 구현을 위해 TIIWR1642 칩을 기반으로 60GHz 대역 밀리미터파 FMCW 송신/수신을 위한 RF 칩셋제어, 거리/속도/각도 검출을 위한 모듈의 개발 및 신호처리 소프트웨어를 포함한 기술을 구현하였다. 생활 정보에 대한 메타 분석으로 생활패턴의 정량적 분석을 통해 개인별 맞춤형 생활패턴 추출을 통해 자기 관리 및 행동 시퀀스를 산출하여 개인별 생활패턴의 분석이 보안 및 안전 응용서비스로 가능할 것으로 기대된다.

• 대한통합의학회지
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• 제11권2호
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• pp.231-242
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• 2023

Purpose : This study aimed to identify ways to improve the quality of physical therapy research and ultimately review the current situation to improve evidence-based decision-making in physical therapy. Methods : For better evidence-based decision-making in physical therapy, researchers should review the quality assessment of articles in more detail and report their findings for valid and appropriate level of evidence and strength of recommendations. The level of evidence affects how well the findings are derived from well-designed literature. The evaluation of the evidence focuses primarily on the study design and the degree of bias that may compromise the validity of the findings. The final recommendation is based on a combination of the study design and literature quality. To uncover gems of information in each paper, a risk of bias assessment should be performed after the literature has been initially selected. Results : Researchers should consider the complexity of the intervention, appropriate grouping, and calculation of effect sizes for the intervention. Researchers conducting systematic reviews should provide a detailed description of the quality assessment performed and present a detailed analysis of their interpretation of the results. The results of systematic reviews and meta-analyses should be interpreted with caution and include a risk of bias assessment. Guidelines for the level of evidence and strength of recommendations should be developed and utilized more broadly to improve reporting practices in physical therapy. Conclusion : Researchers should be knowledgeable about the strengths and limitations of each study design and methodology. In the future, researchers will also need to improve their ability to critically evaluate their findings, given the potential for their results to influence clinical practice.

• Journal of Periodontal and Implant Science
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• 제53권1호
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• pp.2-19
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• 2023

Purpose: Surgical techniques in orthodontics have received widespread attention in recent years. Meanwhile, biomaterials with high molecular content have been introduced, such as platelet concentrates (PCs), which may accelerate orthodontic tooth movement (OTM) and reduce periodontal damage. The present systematic review aimed to answer the following PICO question: "In patients in whom orthodontic surgical techniques are performed (P), what is the effectiveness of using PCs over the surgical site (I) when compared to not placing PCs (C) to achieve faster tooth movement (O)?" Methods: A search was performed in 6 databases. The criteria employed were those described in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses declaration. The present review included studies with a control group that provided information about the influence of PCs on the rate of OTM. Results: The electronic search identified 10 studies that met the established criteria. Conclusions: The included studies were very diverse, making it difficult to draw convincing conclusions. However, a tendency was observed for OTM to be accelerated when PCs were used as an adjuvant for canine distalization after premolar extraction when distalization was started in the same session. Likewise, studies seem to indicate an association between PC injection and the amount of canine retraction. However, it is not possible to affirm that the use of PCs in corticotomy shortens the overall treatment time, as this question has not been studied adequately.

• Restorative Dentistry and Endodontics
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• 제46권2호
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• pp.26.1-26.15
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• 2021

Objectives: The aim of the present systematic review was to investigate the cryopreservation process of dental pulp mesenchymal stromal cells and whether cryopreservation is effective in promoting cell viability and recovery. Materials and Methods: This systematic review was developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and the research question was determined using the population, exposure, comparison, and outcomes strategy. Electronic searches were conducted in the PubMed, Cochrane Library, Science Direct, LILACS, and SciELO databases and in the gray literature (dissertations and thesis databases and Google Scholar) for relevant articles published up to March 2019. Clinical trial studies performed with dental pulp of human permanent or primary teeth, containing concrete information regarding the cryopreservation stages, and with cryopreservation performed for a period of at least 1 week were included in this study. Results: The search strategy resulted in the retrieval of 185 publications. After the application of the eligibility criteria, 21 articles were selected for a qualitative analysis. Conclusions: The cryopreservation process must be carried out in 6 stages: tooth disinfection, pulp extraction, cell isolation, cell proliferation, cryopreservation, and thawing. In addition, it can be inferred that the use of dimethyl sulfoxide, programmable freezing, and storage in liquid nitrogen are associated with a high rate of cell viability after thawing and a high rate of cell proliferation in both primary and permanent teeth.

• 한방재활의학과학회지
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• 제33권3호
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• pp.67-78
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• 2023

Objectives To evaluate the evidence supporting the efficacy and safety of electroacupuncture for lumbar spinal stenosis. Methods We searched eight electronic databases (PubMed, EMBASE, Cochrane Library, Chinese Academic Journals, Research Information Sharing Service, ScienceOn, KMBASE, DBpia) and related two journals up to March 2023. We included randomized controlled trials of testing electroacupuncture for lumbar spinal stenosis patients. The methodological quality of relevant randomized controlled trials assessed by the Cochrane risk of bias tool. Results Among 90 articles that were searched, seven randomized controlled trials involving 474 participants were finally selected in this systematic review. Electroacupuncture was more effective on lumbar spinal stenosis compared with other treatments including analgesics, acupuncture, bed rest and exercise therapy, but showed ambiguous effect compared with physical therapy. Most of the side effects and adverse reactions were reported as minor and temporary. Conclusions Electroacupuncture for lumbar spinal stenosis was more effective than analgesics, acupuncture, bed rest and exercise therapy. In terms of safety, it was limited because there are many papers that do not mention side effects and adverse reactions related to electroacupuncture. Additional studies are needed to determine the effect of electroacupuncture on lumbar spinal stenosis.

• 산업경영시스템학회지
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• 제46권1호
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• pp.105-111
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• 2023

Recently, research on prediction algorithms using deep learning has been actively conducted. In addition, algorithmic trading (auto-trading) based on predictive power of artificial intelligence is also becoming one of the main investment methods in stock trading field, building its own history. Since the possibility of human error is blocked at source and traded mechanically according to the conditions, it is likely to be more profitable than humans in the long run. In particular, for the virtual currency market at least for now, unlike stocks, it is not possible to evaluate the intrinsic value of each cryptocurrencies. So it is far effective to approach them with technical analysis and cryptocurrency market might be the field that the performance of algorithmic trading can be maximized. Currently, the most commonly used artificial intelligence method for financial time series data analysis and forecasting is Long short-term memory(LSTM). However, even t4he LSTM also has deficiencies which constrain its widespread use. Therefore, many improvements are needed in the design of forecasting and investment algorithms in order to increase its utilization in actual investment situations. Meanwhile, Prophet, an artificial intelligence algorithm developed by Facebook (META) in 2017, is used to predict stock and cryptocurrency prices with high prediction accuracy. In particular, it is evaluated that Prophet predicts the price of virtual currencies better than that of stocks. In this study, we aim to show Prophet's virtual currency price prediction accuracy is higher than existing deep learning-based time series prediction method. In addition, we execute mock investment with Prophet predicted value. Evaluating the final value at the end of the investment, most of tested coins exceeded the initial investment recording a positive profit. In future research, we continue to test other coins to determine whether there is a significant difference in the predictive power by coin and therefore can establish investment strategies.

• 한국항행학회논문지
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• 제27권6호
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• pp.877-883
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• 2023

선박의 안전 운항과 해양수산 양식장 관리를 위해 해양수산 빅데이터 구축에 필요한 해양수산 양식장의 경계를 추출한 데이터 셋은 어장 허가 구역과의 일치 여부 조사를 통해 선박의 운항 경로에 불법 설치 시 장애물 정보를 미리 제공할 수 있다. 또한, 해양 사고 등에 의한 피해보상을 위해 필요한 양식장 조업 여부도 파악할 수 있으며, 해당 지자체에서는 어장도와의 중첩 비교를 통해 어장 관리 등에 사용할 수 있다. 선박의 안전 운항을 위한 전자해도에 물표 표시를 통해 운항 경로상의 장애물 파악에 필요한 기초 데이터로써 활용이 높다. 이 연구에서는 양식장의 경계 추출을 위해 충분한 공간해상도를 가지며 짧은 주기로 반복하여 촬영하는 유럽항공우주국 (ESA; europe space agency)의 Sentinel-2 위성영상 자료를 사용하였다. 영상 이미지에서 양식장의 주기별 현황 데이터의 생산을 위해 해상의 구역별 데이터를 부산권, 울산권, 거제·창원권, 고성·통영권, 남해·사천권의 5개 관리 구역으로 나누어 처리하였으며, 구역별 위성영상의 수집과 영상의 강조 처리 과정을 거쳐 양식장의 경계 데이터와 메타정보를 추출하였다.