• 대한교통학회지
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• 제35권4호
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• pp.307-320
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• 2017

본 연구는 메타분석(Meta-Analysis) 기법을 적용하여 ESC(Electronic Stability Control) 시스템의 교통안전 측면의 효과를 평가하였다. 교통안전성의 평가지표로 사고율, 사망사고율, 통제상실 사고율을 설정하였으며 ESC를 주요 키워드로 선정하여 기존 문헌을 수집하였다. 수집된 연구결과를 승산비의 효과크기(Effect-size)로 정리하였고, 개별 연구들 간의 이질성을 고려하여 랜덤효과모형을 적용해 통합 승산비 효과크기를 도출하였다. 분석결과, 사고율의 승산비 효과크기는 0.90으로 차량에 ESC 적용 시 사고율이 10% 감소하는 것으로 나타났다. 또한 사망사고율의 승산비 효과크기는 0.64로 차량에 ESC 시스템 적용 시 사망사고율이 36% 감소하는 것으로 분석되었다. 통제상실 사고율의 승산비 효과크기는 0.73으로 도출되어 ESC 시스템 적용 시통제상실 사고율이 27% 감소하는 것으로 분석되었다. 본 연구의 결과는 상용차 ESC 장착 의무화를 위한 제도 정비 및 관련 기술 개발 전략 수립 시 유용하게 활용될 수 있을 것으로 판단된다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5691-5696
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• 2014

Background: Many clinical trials have been conducted to evaluate sorafenib for the treatment of advanced NSCLC, but the results for efficacy have been inconsistent. The aim of this study was to evaluate the efficacy and safety of sorafenib in patients with advanced NSCLC in more detail by meta-analysis. Methods: This meta-analysis of randomized controlled trials (RCTs) was performed after searching PubMed, EMBASE, ASCO Abstracts, ESMO Abstracts, and the proceedings of major conferences for relevant clinical trials. Two reviewers independently assessed the quality of the trials. Outcomes analysis were disease control rate (DCR), progression- free survival (PFS), overall survival (OS) with 95% confidence intervals (CI) and major toxicity. Subgroup analysis was conducted according to sorafenib monotherapy, in combination with chemotherapy or EGFR-TKI to investigate the preferred therapy strategy. Results: Results reported from 6 RCTs involving 2, 748 patients were included in the analysis. Compared to sorafenib-free group, SBT was not associated with higher DCR (RR 1.31 (0.96- 1.79), p=0.09), PFS (HR 0.82 (0.66-1.02), p=0.07) and OS (HR 1.01 (0.92-1.12), p=0.77). In terms of subgroup results, sorafenib monotherapy was associated with significant superior DCR and longer PFS, but failed to show advantage with regard to OS. Grade 3 or greater sorafenib-related adverse events included fatigue, hypertension, diarrhea, oral mucositis, rash and HFSR. Conclusions: SBT was revealed to yield no improvement in DCR, PFS and OS. However, sorafenib as monotherapy showed some activity in NSCLC. Further evaluation may be considered in subsets of patients who may benefit from this treatment. Sorafenib combined inhibition therapy should be limited unless the choice of platinum-doublet regimen, administration sequence or identification of predictive biomarkers are considered to receive better anti-tumor activity and prevention of resistance mechanisms.

• 한방재활의학과학회지
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• 제29권3호
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• pp.35-49
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• 2019

Objectives The purpose of this research is to evaluate the effectiveness of moxibustion theraphy for frozen shoulder through systematic review and meta-analysis. Methods The effect of moxibustion for frozen shoulder was constructed as a key question to search randomized controlled trials (RCTs) in 16 databases without type of publication restriction. Results A total of 790 studies were searched and 22 RCTs were finally selected through primary and secondary selection/exclusion process. In most of the evaluation indexes used in each study, moxibustion treatment for shoulder pain was statistically significant compared with other treatments. A meta-analysis of effective rate in 10 studies comparing moxibustion with acupuncture and acupuncture showed a statistically significant effect of moxibustion treatment. And there was a significant effect on the improvement of the shoulder mobility, but the effect size of shoulder pain was no significant effect for shoulder pain reduction. In addition in the result of meta-analysis of 4 studies' effective rate comparing moxibustion with electronic acupuncture, the effect of moxibustion was significantly higher than that of electronic acupuncture in frozen shoulder. Conclusions Moxibustion therapy was effective in symptoms in patients with frozen shoulder. However because of the high risk of bias in the quality of the included studies, the applicability of this study seems to be limited. It is thought that future randomized controlled trials will need to be designed and performed by reviewing ways to minimize bias.

• 대한한방내과학회지
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• 제40권1호
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• pp.13-37
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• 2019

Objectives: The purpose of this study was to assess the effects of Korean medicine for non-alcoholic fatty liver disease (NAFLD). We analyzed the result of randomized controlled trials (RCTs) that applied Korean medicine to NAFLD patients through meta analysis and systematic review. Methods: The key question was to the effects of Korean medicine for NAFLD patients according to the PICO-SD (participants, intervention, comparison, outcome, study design) and we included only RCTs. We searched 10 databases including NDSL, KMBASE, KISS, KISTI, KoreaMed, Koreantk, OASIS, Cochrane, Pubmed, EMBASE without a language restriction. We assessed risk of bias by Cochrane group's Risk of Bias tool. Results: The finally selected 12 RCTs were analyzed. Total number of participants was 1189 (male 719, female 470) as 684 and 505 in the oriental medicine group (i.e. herbal drugs, acupuncture, acupoint embedding therapy) and control group (conventional drugs, placebo), respectively. The meta analysis results of examining 7 RCTs comparing the therapeutic efficacy of herbal medicine with that of Western medicine showed statistically significant (p<0.05) differences in the efficacy evaluation, liver function test results, blood lipids, and TNF-${\alpha}$. Furthermore, the meta analysis results of investigating 3 RCTs comparing the therapeutic efficacy of herbal medicine with that of a placebo showed statistically significant (p<0.05) differences in the liver function test results, blood lipids, and waist circumference. Conclusions: The research showed that Korean medicine for NAFLD can be effective treatment. But more studies are required to enhance the level of evidence and we should report on safety.

• 한방재활의학과학회지
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• 제34권2호
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• pp.101-134
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• 2024

Objectives The purpose of this study is to observe the effectiveness of acupotomy treatment for lateral epicondylitis by comparing it with various control groups. Methods We searched 11 domestic and international databases for systematic reviews and meta-analysis. The subjects were studies published from January 1, 2017 to September 1, 2023, and only randomised controlled trials were included. Results 208 studies were searched, of which 21 studies were finally selected. Among the studies published after 2017, the largest number of studies was published in 2019. The average number of participants per study was 72.28±20.26 and the average age was in the 40s. The most frequent intervention in the study was acupotomy alone, and the treatment most often mentioned as a control group was local nerve block. The most used evaluation tool is efficiency. Acupotomy+manipulation had statistically better effect than that of local nerve block in terms of pain (standard mean difference -1.87, 95% confidence interval, -2.18 to -1.57, p<0.00001) and elbow joint function (standard mean difference 2.25, 95% confidence interval, 1.65 to 2.86, p<0.00001). Conclusions As a result of the meta-analysis, the effect of acupotomy added manual therapy treatment was statistically significant compared to the local nerve block frequently used for lateral epicondylitis. Based on these results, it appears that more research on combination treatments other than acupotomy treatment will be needed. Also, it appears that more large-scale randomized controlled studies that strictly adhere to the standards for reporting interventions in controlled trials of acupuncture, risk of bias 2 criteria will be needed.

• 한국콘텐츠학회논문지
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• 제11권10호
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• pp.41-48
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• 2011

최근 특징 선택에서 개미군집 최적화를 위한 선택적 평가 기법이 제안되었다. 이 기법은 불필요하거나 가능성이 적은 후보 해를 실제 평가 과정에서 제외함으로써 계산량을 줄인다. 실험을 통해 이 기법의 우수성을 보였으나, 하나의 데이터만을 사용하였으므로 통계적으로 충분한 신뢰성을 보여주지 못한다. 이 논문의 목적은 선택적 평가 기법의 수렴 특성을 분석하고 결론의 신뢰성을 높이는 것이다. 실험을 위해 UCI 데이터베이스에서 필기, 의료, 음성에 관련된 세가지 데이터를 선택하였다. 이들의 특징 집합 크기는 256부터 617까지 분포한다. 통계적으로 안정된 데이터를 얻기 위해, 이들 각각에 대해 프로그램을 독립적으로 12번 실행하였다. 긴 시간에 걸친 수렴을 관찰하기 위해, 각각의 프로그램 실행은 72시간 동안 이루어졌다. 실험 데이터의 분석을 바탕으로, 선택적 평가 기법의 우수성에 대한 이유와 이 기법의 적용 범위에 대해 기술한다.

• 한국문헌정보학회지
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• 제55권2호
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• pp.227-261
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• 2021

본 연구의 목적은 학교도서관 평가 실태를 분석하여 학교도서관 평가의 발전 방향에 대한 시사점을 얻으려는 데에 있다. 이를 위해 교육부, 교육청 및 문화체육관광부를 중심으로 수행되는 학교도서관 관련 조사, 컨설팅 및 평가를 메타평가를 활용하여 분석하고, 사서교사를 대상으로 심층 면담 조사를 실시하였다. 분석 결과, 각 기관의 평가 중복, 국가의 학교도서관 발전계획의 반영 미비, 공모형 평가로 인한 참여율 저조, 교육 평가지표 미비 등의 문제점이 발견되었다. 이러한 문제를 해결하기 위한 학교도서관 운영평가의 개선방안은 법률에 평가 주체의 역할 명시, 국가의 도서관 발전계획의 반영, 기관 간 평가 네트워크 구축, 사례 공유 시스템 운영, 교육청의 조사 및 컨설팅과 전국 도서관 운영 평가의 연계 방안 마련을 제안하였다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권12호
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• pp.4531-4544
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• 2021

Because the traditional network information security vulnerability risk assessment method does not set the weight, it is easy for security personnel to fail to evaluate the value of information security vulnerability risk according to the calculation value of network centrality, resulting in poor evaluation effect. Therefore, based on the network security data element feature system, this study designed a quantitative assessment method of network information security vulnerability detection risk under single transmission state. In the case of single transmission state, the multi-dimensional analysis of network information security vulnerability is carried out by using the analysis model. On this basis, the weight is set, and the intrinsic attribute value of information security vulnerability is quantified by using the qualitative method. In order to comprehensively evaluate information security vulnerability, the efficacy coefficient method is used to transform information security vulnerability associated risk, and the information security vulnerability risk value is obtained, so as to realize the quantitative evaluation of network information security vulnerability detection under single transmission state. The calculated values of network centrality of the traditional method and the proposed method are tested respectively, and the evaluation of the two methods is evaluated according to the calculated results. The experimental results show that the proposed method can be used to calculate the network centrality value in the complex information security vulnerability space network, and the output evaluation result has a high signal-to-noise ratio, and the evaluation effect is obviously better than the traditional method.

• 한방안이비인후피부과학회지
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• 제35권3호
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• pp.48-65
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• 2022

Objectives : This study was conducted to find out the effectiveness and safety of herbal medicine eye drops on conjunctivitis. Methods : We searched randomized controlled trials on conjunctivitis through 10 DBs from the start to April 27, 2022. Study collection and data extraction, and evaluation of risk of bias were conducted by two independent researchers. The evaluation of the risk of bias in included RCTs was carried out by using Cochrane risk-of-bias tool. And the data synthesis was conducted by using Review Manager(RevMan, ver.5.4). Results : Total of 106 studies are researched and 7 studies of them are finally included. 1. The herbal medicine eye drops are more effective on than the western medicine eye drops, but the heterogeneity was very high. So we conducted sensitivity analysis and compared to the herbal medicine eye drops and the western medicine eye drops, the total effective rate was higher in the herbal medicine eye drops and the heterogeneity was somewhat reduced. 2. In the subgroup analysis, Fufang Xiongdan eye drops and Houttuynia cordata Thunb eye drops are more effective than the western medicine. It may represent substantial heterogeneity. 3. In the subgroup analysis, the herbal medicine eye drops are more effective than antibiotic and antiviral eye drops on acute bacterial conjunctivitis, but showed high heterogeneity. On the other hand, the herbal medicine eye drops are more effective than antibiotic and antiviral eyed drops on acute viral conjuctivitis and showed low heterogeneity. 4. In the subgroup analysis, we compared the effectiveness of herbal and western medicine eye drops according to total effectiveness rate evaluation methods. When comparing the studies calculating the total effective rate by the sum of 'Cured', 'Significantly Impaired', and 'Improved', the effective rate of the herbal medicine eye drops was higher than that of the western medicine eye drops, and the heterogeneity was very low. 5. In most studies, side effects of herbal medicine eye drops were absent or mild. Conclusions : This study shows that herbal medicine eye drops may be more effective than western medicine eye drops and have safety. But further researches are needed to resolve the heterogeneity of this study.

• 한국수학교육학회지시리즈A:수학교육
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• 제55권2호
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• pp.171-192
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• 2016

As teachers' competency is evaluated based on their teaching performance. pre-service teachers need to have an opportunity to reflect on themselves by systematically analyzing and evaluating their own lesson planning and teaching performance through self-assessment. In this study, we aimed to examine what evaluation criteria for lesson planning and teaching performance pre-service mathematics teachers consider in the process of self-assessment. This study used a mixed-methods research design. To draw the self-evaluation criteria for lesson planning and teaching performance, pre-service self-reported assessments were analyzed using qualitative analyses. In addition, descriptive statistics were used to investigate the pre-service teachers' distribution across the criteria and check the ratio of pre-service mathematics teachers for each element. As a result, it was disclosed that pre-service mathematics teachers considered eight elements in self evaluating their own lesson planning and teaching performance. In addition, we found that pre-service mathematics teachers tended to consider Pedagogical Content Knowledge (PCK) more than Subject-Matter Knowledge (SMK). Moreover, the results of this study provide educational implications for the curriculum in the pre-service teacher's education program.