• Journal of Korean Clinical Nursing Research
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• v.19 no.3
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• pp.432-442
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• 2013

Purpose: The purpose of this study was to describe restraint use in care of patients with psychiatric disorders in an attempt to avoid unnecessary restraint use and provide information for developing standards regarding restraint use as a therapeutic maneuver. Methods: For this descriptive study, discharge records from N National Mental Hospital in the year 2009 were reviewed by trained nurses during Dec. 24, 2010 and Mar. 31, 2011. There were 596 restrains applied on 232 of 1,322 discharges. Data collected include general characteristic of patients, the frequency of restraint use, time since admission when restraint was applied, time of the day when restraint was applied, duration of restraint application, place of occurrence, reasons for restraint use, and degree of damage to the patent. Work experience of nurses who applied restraints, number of workforce at the time of restraint, and season of the year was also identified. Descriptive statistics, Chi-square test, t-test, ANOVA, $Scheff{\grave{e}}$ and Jonckheere-Terpstra were applied using SPSS 14.0 to analyze the data. Results: There were 596 restraint uses among 232 patients. Restraints were applied most frequently on males in their 40s, patients diagnosed with schizophrenia, and patients repeating admissions more than 6 times. Restraints were frequently applied within first week following admission, between 16:00 and 20:00, and the average duration of restraint was 5 hours. There were significant differences according to diagnoses of patients in the season restraint occured, time, place of occurrence, reason for restraint, and duration of restraint. Patients with alcoholism received longer restraint application. Conclusion: In order to avoid unnecessary restraint use in patients with psychiatric disorders, nurses and other health care team members need to acknowledge a group of patients such as patients with schizophrenia and alcoholism who relatively frequently restrained or receiving longer restraint. Reasonable and careful decision need to be made when applying restraint in the care of patients with alcohol problem.

• Journal of Life Science
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• v.32 no.10
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• pp.812-820
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• 2022

Depression is a psychiatric disorder characterized by depressed mood, anhedonia, fatigue, and altered cognitive function, leading to a decline in daily functioning. In addition, depression is a serious and common mental illness not only in an individual's life but also in society, so it must be actively treated. Autophagy is involved in the pathophysiological mechanism of mental illness. According to a recent study, it is known that autophagy-induced apoptosis affects neuroplasticity and causes depression and that antidepressants regulate autophagy. Autophagy is a catabolic process that degradation and removes unnecessary organelles or proteins through a lysosome. And, it is essential for maintaining cellular homeostasis. Autophagy is activated in stress conditions, and depression is a stress-related disease. Stress causes damage to cellular homeostasis. Recently, although the role of autophagy mechanisms in neurons has been investigated, the autophagy of depression has not been fully studied. This review highlights the new evidence for the involvement of autophagy in the pathophysiological mechanisms and treatment of depression. To highlight the evidence, we present results from clinical and preclinical studies showing that autophagy is associated with depression. Understanding the relevance of autophagy to depression and the limitations of research suggest that autophagy regulation may provide a new direction for antidepressant development.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.635-643
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• 2017

This study examines the relationship between emotional labor and depression in dental hygienists. Data were collected from 186 dental hygienists working in dental clinics in Daegu from early March to early April 2016. The survey was composed of questionnaires related to general characteristics, work-related characteristics, emotional labor, and depression. As a result of analyzing the subordinate factors of emotional labor, 57.0% of the factors of 'organization support and protection system' were the highest, and the effect of emotional labor on depression was 'emotionaldisharmony and damage', 'Organizational support and protection system', and especially, the ' emotionaldisharmany and damage' factors were 4.042 times higher than normal. The dental hygienist's degree of emotional labor risk is high, and education, prevention and management measures for emotional labor will be prepared. In addition, emotional labor affects the depression of dental hygienists as well, and comprehensive mental health measures are needed to take into consideration general and occupational characteristics that affect depression.

• The Journal of the Korea Contents Association
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• v.18 no.5
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• pp.456-463
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• 2018

Increases in disasters and damage caused by the disasters in modern society, have a negative impact on local economy. In particular, a local economic downturn leads to a deterioration in quality of life of local residents and causes mental and material damage. Therefore, in order to achieve stable and sustainable local economic development, it is necessary to strengthen the resilience of the local economy. This study aims to estimate indicators of local economic resilience of Jindo County after the Sewol Ferry disaster, analyze a trend of the economic level after the disaster through time series data and suggest improvement plans of the local crisis management and restoration policy that considers future economic resilience. Results of this study showed that a decrease in the number of tourists and of workers in related industries hit tourism industry, causing a loss to the local economy and that an increase in a drinking rate of and stress awareness rate of local residents was a stress factor due to disaster impacts. These findings provides policy implications that it is necessary to make efforts for improving the depressed local image by utilizing local resources in the area, to build a sustainable long-term economic recovery policy and to provide psychological treatment and the relevant government and local government's support for relieving the stress of local residents due to the disaster impacts.

• Biomolecules & Therapeutics
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• v.17 no.1
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• pp.47-56
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• 2009

Schizandra chinensis (S. chinensis) exhibits a harmless, 'adaptogen-type' effect leading to improvements in mental performance and learning efficacy in brain. Activated microglia contributes to neuronal injury by releasing neurotoxic products, which make it important to regulate microglial activation to prevent further cytological as well as functional brain damage. However, the effect of S. chinensis on microglial activation has not been examined yet. We have investigated the effects of four compounds (Gomisin A, Gomisin N, Schizandrin and Schizandrol A) from S. chinensis on lipopolysaccharide (LPS)-induced microglial activation. In this study, BV2 microglial cells were activated with LPS and the microglial activation was assessed by up-regulation of activation markers such as nitric oxide (NO), reactive oxygen species (ROS), and matrix metalloproteinase-9 (MMP-9). The results showed that all four compounds significantly reduced the intracellular level of ROS, the release of NO and MMP-9 as well as LPS-induced phosphorylation of ERK1/2. These results strongly suggested that S. chinensis may be useful to modulate inflammation-mediated brain damage by regulating microglial activation.

• Korean Journal of Culture and Social Issue
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• v.13 no.4
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• pp.53-82
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• 2007

This study, driven by the question of 'what the experience of healing of female sexual abuse victims is like,' explores the process the victims undergo as they heal from the traumas. Using the methods suggested by Strauss and Corbin's Grounded theory, it analyzes nine interviews taken from victims who have received counseling. The study found that the central phenomena that take place in the process of their healing is 'mental pain due to the damage caused by sexual abuse,' the causal conditions are 'the recognition of the sexual abuse' and 'desperation,' and the contextual conditions are 'the reaction of the close ones of the victims,' 'the preconception about sexuality,' and 'the incarceration and punishment of the offenders.' The victims have been intervened in the healing process by 'being supported' and 're-interpreting the meaning of the damage caused by sexual abuse,' and are found to utilize the interactive strategy among 'facing their emotions,' 'learning new coping strategies,' and 'hoping for the future.' They are also found, as a result of the healing, to 'live unafraid as survivors' and 'have structured their lives in a new way.' This study is of significance in systematically elucidating the healing process and the related elements found through the voices of the survivors of sexual abuse in the context of the Korean society and culture. The limits of this study and suggestions about the studies that should follow this one are included as well.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.9 no.2
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• pp.127-130
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• 2013

Hypoxic ischemic encephalopathy (HIE) is an important cause of permanent damage to central nervous system cells, most cases with oxygen deprivation in the nenonate due to birth asphyxia. Survival children with HIE develop problems such as cerebral palsy, mental retardation, learning difficulties, and other permanent neuro-developmental disabilities. This article report two cases of the children with HIE who had be traumatized on their teeth from oropharyngeal airway (OPA) in the emergency situation. The patients with the disease accompanying seizure or convulsion, needs special consideration for the prevention from dental trauma in emergency airway management.

• Journal of The Korean Society of Clinical Toxicology
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• v.15 no.1
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• pp.56-59
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• 2017

Pneumatosis cystoides intestinalis and portomesenteric venous gas are uncommon radiological findings, but are found commonly in cases of bowel ischemia, or as a result of various non-ischemic conditions. A 72-year-old man visited an emergency center with altered mental status 2 hours after ingestion of an unknown pesticide. On physical examination, he showed the characteristic hydrocarbon or garlic-like odor, miotic pupils with no response to light, rhinorrhea, shallow respiration, bronchorrhea, and sweating over his face, chest and abdomen. Laboratory results revealed decreased serum cholinesterase, as well as elevated amylase and lipase level. We made the clinical diagnosis of organophosphate poisoning in this patient based on the clinical features, duration of symptoms and signs, and level of serum cholinesterase. Activated charcoal, fluid, and antidotes were administered after gastric lavage. A computerized tomography scan of the abdomen with intravenous contrast showed acute pancreatitis, poor enhancement of the small bowel, pneumatosis cystoides intestinalis, portomesenteric venous gas and ascites. Emergent laparotomy could not be performed because of his poor physical condition and refusal of treatment by his family. The possible mechanisms were believed to be direct intestinal mucosal damage by pancreatic enzymes and secondary mucosal disruption due to bowel ischemia caused by shock and the use of inotropics. Physicians should be warned about the possibility of pneumatosis cystoides intestinalis and portomesenteric venous gas as a complication of pancreatitis following anticholinesterase poisoning.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.39 no.4
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• pp.117-124
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• 2016

Stress is resistance to stimuli to destroy a balance of mind and body in order to maintain an original steady state : A type of response and avoidance. Mild stress, which happens in tension, has a positive effect to improve concentration, but most of stress is likely to be a main factor to damage health. This is because it causes physical ailments and psychological diseases (e.g., depression, anger, frustration, loneliness, and anxiety). The purpose of this study is to analyze the difference between two groups, daytime and night university students, on ego-state, stressors, and stress coping types to improve their academic achievement by reducing their stress. There were 266 university students, who participated in a survey from November 30, 2015 until September 30, 2016. The study employed three measuring instruments : Ego-gram, stressor scale, and stress coping type scale. All the collected data were analyzed through regression analysis and t-test. The results of the regression analysis showed no significant differences in ego-state, stressors, and stress coping types between two groups. However, the results of t-test showed significant difference between the two groups : In terms of ego-state, a CP (Critical Parent) average of the night university students was significantly higher than the daytime university students'. Also, there is a significant difference in employment, future issues, and economic issues : the daytime university students considered employment and future issues more serious, while the night university students had more mental burdens of economic issues. When it comes to coping stress types, there was no significant difference between the two groups.

• Investigative Magnetic Resonance Imaging
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• v.24 no.1
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• pp.30-37
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• 2020

Purpose: Preterm infants are at high risk for adverse neurodevelopmental outcomes. Magnetic resonance imaging (MRI) has been proposed as a means of predicting neurodevelopmental outcomes in this population. It is controversial whether diffuse excessive high signal intensity (DEHSI) represents damage to the white matter or delayed myelination in preterm infants. This study investigated MRI findings for predicting the severity of neurodevelopmental outcomes and assessing whether preterm infants with DEHSI near term-equivalent age have abnormal neurodevelopmental outcomes. Materials and Methods: Preterm infants (n = 64, gestational age at birth < 35 weeks) undergoing brain MRI near term-equivalent age and subsequent neurodevelopmental outcomes were evaluated between 18 and 24 months of age. The associations of MRI findings and the risk of severe cognitive delay, severe psychomotor delay, cerebral palsy (CP), and neurosensory impairment were analyzed. The associations of DEHSI with risks of severe cognitive delay, severe psychomotor delay, CP, and neurosensory impairment (hearing or visual impairment) were analyzed. Outcome data were evaluated by logistic regression and the Fisher's exact test. Results: There were significant associations between abnormal white matter findings and delayed mental development, delayed psychomotor development, neurosensory impairment, and presence of CP. The presence of DEHSI was not correlated with delayed neurodevelopmental outcomes or presence of CP. In multivariate logistic regression analyses, cystic encephalomalacia, punctate lesion, loss of white matter volume and ventricular dilation were significantly associated with CP. Conclusion: Abnormal MRI findings near term-equivalent age in preterm infants predict adverse neurodevelopmental outcomes. No significant association between DEHSI and adverse neurodevelopmental outcomes was demonstrated.