• 대한물리의학회지
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• 제5권2호
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• pp.211-221
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• 2010

Purpose : The purpose of this study is to find out the effects of combined exercise including walking and yoga on cognitive functions in the elderly women. Methods : Sixteen elderly women aged above 65 are invited in this study. Each subject participated in exercise three times a week for eight weeks from July 14th to September 13th in 2008. The changes between pre and post exercise are analyzed by Wilcoxon sign rank test and repeated ANOVA test with SPSS (ver 17.0) package program. Results : After exercise, In the below 23 points group, only interference STROOP test (p<.05) among sub items of Cognition Scale for Older Adults (CSOA) is improved significantly. In the above 24 points group, words memory (p<.05), delayed recall (p<.05), and picture naming (p<.05) among sub items of CSOA are improved significantly. But it is no different to the change patterns among two groups. Conclusion : These results show that combined exercise including walking and yoga is helpful to improve cognitive functions. And we find that exercise is helpful in the above 24 points elderly women more than in the below 23 points.

• 대한한의학회지
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• 제21권4호
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• pp.236-241
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• 2000

Background and Purpose : Cerebrovascular accident is a serious neurologic event. It can have temporary or permanent effects on survivors, including memory, cognition and volitional control of voiding. The purpose of this study is to evaluate the clinical effect of moxibustion in patients with voiding dysfunction after a cerebrovascular accident. Methods : Twenty patients with post-stroke voiding dysfunction were studied. All patients had computerized tomography(CT) and magnetic resonance imaging(MRI) to localize the lesion in the central nervous system. They were randomly divided into two groups : the control and moxibustion group. Ten of twenty patients underwent moxibustion treatment by randomization. The moxibustion group receieved moxibustion at three points : Chung-guk (Conception Vessel CV3), Kuanwon (CV4) Kihae (CV6). Residual urine volume evaluation was undertaken in all patients. Results : 1. IIn the balanced bladder time, the moxibustion group had the shorter time than non moxibustion group. But there was no significiant difference between the moxibustion group and non-moxibustion group. 2. In the residual urine volume, the moxibustion group and non-moxibustion group showed a tendency to decrease. But there was no significiant difference between the moxibustion group and non-moxibustion group. Conclusions : Though further study is needed, our findings suggested that the time of achieving balanced voiding was shorter with moxibustion than in the control group.

• Clinical and Experimental Pediatrics
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• 제57권3호
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• pp.101-109
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• 2014

The use of glucocorticoids (GCs) in the perinatal period is suspected of being associated with adverse effects on long-term neurodevelopmental outcomes for preterm infants. Repeated administration of antenatal GCs to mothers at risk of preterm birth may adversely affect fetal growth and head circumference. Fetal exposure to excess GCs during critical periods of brain development may profoundly modify the limbic system (primarily the hippocampus), resulting in long-term effects on cognition, behavior, memory, co-ordination of the autonomic nervous system, and regulation of the endocrine system later in adult life. Postnatal GC treatment for chronic lung disease in premature infants, particularly involving the use of dexamethasone, has been shown to induce neurodevelopmental impairment and increases the risk of cerebral palsy. In contrast to studies involving postnatal dexamethasone, long-term follow-up studies for hydrocortisone therapy have not revealed adverse effects on neurodevelopmental outcomes. In experimental studies on animals, GCs has been shown to impair neurogenesis, and induce neuronal apoptosis in the immature brains of newborn animals. A recent study has demonstrated that dexamethasone-induced hypomyelination may result from the apoptotic degeneration of oligodendrocyte progenitors in the immature brain. Thus, based on clinical and experimental studies, there is enough evidence to advice caution regarding the use of GCs in the perinatal period; and moreover, the potential long-term effects of GCs on brain development need to be determined.

• 종양간호연구
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• 제12권1호
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• pp.1-11
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• 2012

Purpose: This study reviewed articles related to breast cancer, cognitive function and chemotherapy available in 4 databases. Methods: The researcher reviewed 32 pieces of literature that were published between January 2001 and November 2011. Results: Within the last decade, several studies have investigated whether adjuvant treatment of breast cancer affects cognitive function. A number of prospective studies have reported inconsistent results regarding whether chemotherapy affects cognitive function. Approximately half of the studies reported subtle cognitive decline in a wide range of domains among some breast cancer patients following chemotherapy, and others did not. Conclusion: Breast cancer patients receiving adjuvant chemotherapy showed the most deterioration and the most persistent decline in cognitive function. Since cognitive impairment is subtle, if evident at all, discrepant findings are due to hormonal, physiological, psychological or temporal confounding variables and differences in study design. Especially, that chemotherapy may impair memory, executive function, attention and visuospatial function in women with breast cancer.

• 품질경영학회지
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• 제20권2호
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• pp.109-117
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• 1992

An inspection task largely can be seen as a job divided up into a series of visual search and classification subtasks. In these subtasks, an Inspector must performs to compare the standard references proposed in visual environments and recalled in his memory with the visual stimuli to be inspected. It means that the judgement of similarity should be demanded on inspection tasks. Therefore, the inspector's ability for the judgement of similarity and the difference similarity between inspection materials are important factors to effect on performances in inspection tasks. In this paper, to analysis the effect of these factors on inspection time, an inspection task is designed and suggested by means of computer simulator. Especially, the skin conductance responses(SCR) of subjects are measured to evaluate the complexity of tasks due to the difference of similarity between materials. In the results of experiment, the more similar or different the difference of similarity between materials is, the shorter the inspection time is because of the reduction of task complexity. And, When the inspector's cognition for similarity between materials is consistanct, the inpsection time is improved. Concludingly, the consistency of reponses for similarity judgement becomes a measurement to present the performance levels. And the information of inspection time that due to the difference of similarity between materials must be considered in planning and scheduling inspection tasks.

• 한국식품영양학회지
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• 제23권4호
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• pp.485-491
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• 2010

With an increase in the number of people suffering from ageing-related diseases in our rapidly aging society, interests in natural products such as maca(Lepidium meyenii), which has properties of enhancing cognition and sexual performance, have increased. This study was conducted to assess the effects of 7 weeks of maca extract supplementation(0.5~2.0 g/kg BW) on scopolamine-induced amnesia in mice and on sperm count in male mice. All doses of maca supplementation significantly protected against scopolamine-induced amnesia as determined by a Morris water maze, but not according to passive avoidance tests. Maca supplementation did not affect acetylcholinesterase activity in the whole brain, nor the testicular sperm count of male mice. This study suggests that maca may have some neuroprotective properties in mice, which will be further examined by future studies.

• 한국실내디자인학회논문집
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• 제39호
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• pp.116-123
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• 2003

The purpose of this study is to demonstrate the relationship between the results of the analysis of the overseas railroad station buildings, which was conducted using the factors of environmental cognition for the purpose of designing an interior environment for the Incheon International Airport Railroad station that will be newly constructed, and the plan that could be applied to the design of interior environment for the airport railroad station. The station with a complex interior space layout and relatively larger space tends to be difficult to predict or forecast passenger's needs or recognition element in approaching stage of intoner environment design since the human's biological memory system is greatly affected by such factors. Cognitive approach at empirical standpoint would possibly create the design, of which elements will Implement the functions of their own as such approach enables necessary information to be structured in a systematical way and manner In implementing interior environment design for such stations to be built for the first time in Korea, behavioral approach based on systematic theory proved to be very crucial. Under such a background, the study was aimed at extracting the assessment elements for interior environment design, then setting the frame of cognitive approach to eventually propose the guideline in approaching to interior environment design.

• 컴퓨터교육학회논문지
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• 제13권1호
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• pp.37-44
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• 2010

최근 효율적인 외국어 학습 및 진단을 위해 외국어학습의 뇌공학적 접근이 활발하게 이루어지고 있다. 본 논문은 기존의 지필고사를 대체할 수 있는 뇌공학적 외국어 능숙도 진단 도구를 개발하는 것을 목표로 이를 위해 기존 언어심리학 과제에서 주로 사용되었던 테스트들을 기반으로 외국어 능숙도 진단을 위한 도구를 개발 하였다. 본 논문에서 제안한 도구들은 학습자의 기억능력, 이해능력, 산출능력을 5가지 테스트를 통하여 대뇌의 정보처리 양상을 간접적으로 측정한다.

• 농촌의학ㆍ지역보건
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• 제45권3호
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• pp.121-129
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• 2020

치매가 진행되면서 인지기능 저하로 인해 기억력 감퇴, 언어능력 저하, 시공간 파악능력 저하, 판단력 저하가 오게 되어 일상생활과 관련된 과제들을 수행하는데 어려움이 발생하게 된다. 경도인지장애를 동반한 치매 환자들을 위한 지역사회 기반 비 약물적 중재치료는 인지, 운동치료, 예술과 같은 활동을 포함 작업, 운동, 오락치료가 있고, 환자들의 삶의 질, 라이프케어의 증진에 영향을 준다. 본 연구는 라이프케어 증진을 위한 후마네트 운동 프로그램이 노인의 인지기능, 우울기능에 미치는 영향을 알아보고자, 경기도에 소재한 데이케어센터에서 실험군 15명, 대조군 15명을 8주간 실시하였다. 두 집단간에 지남력, 기억회상, 주의집중 및 계산, 우울기능에 유의한 차이가 있었고, 기억등록, 언어기능, 이해 및 판단에는 유의한 결과를 얻지 못하였다. 후마네트 운동은 치매 노인에게 인지기능 향상과, 우울기능에 효과가 있다고 판단되었다. 집안 내 생활이 많아지고, 운동기능, 우울기능, 인지기능이 감소될 수 있는 노인, 치매, 경도인지장애 환자들을 대상으로 라이프케어 증진을 위한 후마네트 운동 프로그램을 적용할 수 있는 방안을 마련하고 그 효과를 반복 측정하는 연구를 제언한다.

• 한국식품영양과학회지
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• 제39권11호
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• pp.1691-1694
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• 2010

본 실험에서는 발효더덕을 제조한 후 발효더덕의 건망증에 대한 효과를 scoplamnine으로 유도된 건망증 모델을 이용하여 수동회피시험(passive avoidance test)과 Morris 수중미로시험(Morris water maze test)을 이용하여 행동학적 변화를 통하여 발효더덕의 기억력 개선 능력 여부를 확인하고자 하였다. 더덕 및 발효더덕 추출물 167, 333, 667 mg/kg을 경구투여 한 결과 발효더덕 추출물의 333 mg/kg 및 667 mg/kg 그룹에서 각각 $120.9{\pm}15.3$초 및 $140.7{\pm}18.0$초에 대하여 통계적으로 유의성 있게 latency time이 증가하였으며, 특히 333 mg/kg의 용량에서 대조군의 85% 수준으로 회복하는 것을 확인하였다. 또한, Morris water maze test를 실시에서도 더덕 및 발효더덕 추출물 처리군에서는 scopolamine에 의한 기억 손상이 개선되어 대조군의 escape latency 수준으로 회복되었다. 이상의 결과 발효더덕 추출물의 경구섭취는 scopolamine으로 유도된 기억력 감퇴 동물모델에서 기억력 개선 및 인지능력을 향상시킬 수 있다고 생각되며, 효과의 기전 및 효능성분을 확인 연구가 진행되어야 할 것으로 생각된다.