• The Korean Journal of Physiology
• /
• v.29 no.2
• /
• pp.191-202
• /
• 1995

The purpose of this study was to compare effects of insulin and IGFs on growth, apical membrane enzyme activities and membrane transport systems of primary cultured rabbit kidney proximal tubule cells. Results were as follows: 1. Insulin and IGF-I produced significant growth stimulatory effects at $5{\times}10^{-10}M.\;IGF-II(5×10^{-10}\;M)$ did not stimulate significant cell growth. 2. Insulin stimulated the phosphorylation of a 97 KD protein. It was difficult to determine whether this band represents insulin and/or the IGF-I receptor. 3. The activities of apical membrane enzymes (alkaline phosphatase, leucine aminopeptidase, and ${\gamma}-glutamyl \;transpeptidase)$ were observed to be diminished after the cells were placed in the culture environment. 4. The uptake of ${\alpha}-MG,$ Pi and Na was significantly increased in cells incubated with insulin or IGF-I, IGF-II had no effect on the uptake of these substrates. 5. Na-pump activity, as assayed by Rb uptake, was significantly increased in cells treated with insulin or IGFs. In conclusion, insulin and IGF-I exert stimulatory effects on growth and membrane transporter(glucose, Na, Pi, and Na-pump) activities in primary cultured rabbit kidney proximal tubule cells. IGF-II had no effect on cell growth and membrane transporter(glucose, Na and Pi) activities.

• Membrane and Water Treatment
• /
• v.5 no.2
• /
• pp.73-86
• /
• 2014

Membrane fouling is a major challenge limiting the use of membrane applications. In this study high induced shear rates were utilized at the membrane surface in order to reduce the organic and inorganic scaling by using the torsional vibration of flat sheet membranes. The performances of a vibratory shear-enhanced processing (VSEP) system for the ultrafiltration (UF), nanofiltration (NF) and reverse osmosis (RO) membrane filtration of industrial dairy wastewater were investigated. The vibration and non-vibration methods were compared with the same membrane and operational parameters during the purification of real dairy industrial process wastewater. In the initial experiments, short-term tests were carried out in which the effects of vibration amplitude, recirculation flow rate and transmembrane pressure were measured and compared. The permeate flux, turbidity, conductivity and chemical oxygen demand (COD) reduction of dairy wastewater were investigated by using UF, NF and RO membranes with vibration and non-vibration methods. In the subsequent experiments, concentration tests were also carried out. Finally, scanning electron microscopy (SEM) revealed that the vibration method gave a better performance, which can be attributed to the higher membrane shear rate, which reduces the concentration of solids at the membrane, and the transmission.

• Proceedings of the Membrane Society of Korea Conference
• /
• 1993.10a
• /
• pp.34-35
• /
• 1993

The study was undertaken to investigate the effects of ZnCl$_2$ in polysulfone(PSf)/N-methylpyrrolidone(NMP) on the structure and performance of its membrane. The effects of additives on the performances of membranes have been studied. It has been shown that some low molecular weight additives in polysulfone(PSf) casting solutions have effects on the performances of membranes cast from these solutions. It had been reported that ZnCl$_2$, as the additives-in PSf casting solution, decreases water permeability and increases the rejection rate of its membrane.

• Membrane and Water Treatment
• /
• v.1 no.2
• /
• pp.93-101
• /
• 2010

This study examined the effects of feed water chemistry and membrane fouling on the rejection of trace organics by a loose nanofiltration membrane. One ionisable and one non-ionisable trace organics were selected for investigation. Results reported here indicate that the solution pH and ionic strength can markedly influence the removal of the ionisable trace organic compound sulfamethoxazole. These observations were explained by electrostatic interactions between the solutes and the membrane surface and by the speciation of the ionisable compound. On the other hand, no appreciable effects of solution pH and ionic strength on the rejection of the neutral compound carbamazepine were observed in this study. In addition, membrane fouling has also been shown to exert some considerable impact on the rejection of trace organics. However, the underlying mechanisms remain somewhat unclear and are subject to on-going investigation.

• Proceedings of the Membrane Society of Korea Conference
• /
• 1998.09a
• /
• pp.31-55
• /
• 1998

1. Performance of RO membrane depends on chain structure (packing density) 2. Crosslinking of main chain is essential for the high performance RO membranes 3. Various bisphenols and polyaminostyrene can be promising materials for the fabrication of RO membranes. 4. By using of blend technique of reactant, we can expect broad spectrum of RO membrane and synergetic effects in membrane performance.

• Transactions of the Korean Society of Automotive Engineers
• /
• v.4 no.6
• /
• pp.27-38
• /
• 1996

A two-dimensional FEM program, which considers bending effects in the membrane fromulation, was developed under plane strain assumption for analyzing forming processes of an arbitrarily shaped draw-die of automotive panels. For the evaluation of bending effects with membrane elements, the bending equivalent forces and stiffnesses are calculated from the bending moment computed using the changes in curvature of the formed shape of two membrane ones. The curves depicted with 3 nodes are described by a circle, a quadratic equation, and a cubic equation, respectively, and in the simulation of the stretch/draw sections of an automotive inner panel, three different description results are compared each other. Also, the bending results are compared with membrane results and measurements in order to verify the validity of the developed program.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.22 no.3
• /
• pp.493-503
• /
• 1998

The sectional forming analysis considering bending effects from the geometrically deformed shape of two linear membrane finite elements(called super element) was performed under plane strain assumption for analyzing forming processes of an arbitrarily shaped draw-die. For the evaluation of bending effects, the bending equivalent forces are calculated from the bending moment computed using the changes in the interior angle at the middle node of super element, and are agumented to the membrane stretch forces. In order to verify the validity of the bending formulation, the simulation results for the stretch, draw, and bend sections were compared with membrane analysis results and measurements.

• Journal of Korean Society of Water and Wastewater
• /
• v.29 no.2
• /
• pp.251-259
• /
• 2015

The main objective of this research is to study feasibility for applying metal membrane to remove particles from air scouring membrane backwash water. Also, the research was conducted to investigate the influence of polyamine coagulation on floc growth in membrane backwash water as pretreatment for removal particles. From the results of experiments for evaluating the influence of polyamine coagulation on floc growth, it was investigated that particles in the rage of $2{\sim}50{\mu}m$ grew up to $30{\sim}5,000{\mu}m$. In addition, all six metal membranes showed lower removal efficiency, which was 0.87~13.89%, in the case of no polyamine coagulant. On the other hand, in the case of injecting polyamine coagulant, those did extremely high efficiency in 56~92%. From the SEM(Scanning Electron Microscope) images of filtered wiremesh and metal foam membrane, sieve effects were predominant for liquid solid separation in wiremesh and adsorption and diffusion capture effects were predominant in metal foam membrane.

• Membrane and Water Treatment
• /
• v.5 no.1
• /
• pp.57-71
• /
• 2014

In this study, a theoretical model for the transport phenomena in an Air Gap Membrane Distillation used for desalination was developed. The model is based on the conservation equations for the mass, momentum, energy and species within the feed water solution as well as on the mass and energy balances on the membrane sides. The rarefaction impacts are taken into consideration showing their effects on process parameters particularly permeate flow and thermal efficiency. The theoretical model was validated with available data and was found in good agreement especially when the slip condition is introduced. The rarefaction impact was found considerable inducing an increase in the permeate flux and the thermal efficiency.

• Preventive Nutrition and Food Science
• /
• v.1 no.1
• /
• pp.143-150
• /
• 1996

The membrane fatty acid composition of tumor cell can be modified either in cell by altering the lipid composition of the medium of during growth in animals by changing the dietaty fat composition. These modifications are associated with changes in membrane physical properties and certain cellular functions, including carrier-mediated transport and enzyme contained within the membrane. Such effects influence the transport of nutrients and chemotherapeutic agents in cancer cells .Fatty acid modification also can enhance the sensitivity of the neoplastic cell to chemotherapy. The alteration in plasma membrane composition will be affected through dietary supplementations and the potential value to cancer patients could be a better understanding of the effects of diet on responsiveness of neoplasms to chemotherapy, i.e. cancer patients' chances for a "cure" can be improved by diet changes prior to treatment.