• Title/Summary/Keyword: medicinal material

Search Result 491, Processing Time 0.032 seconds

The Effect of Roots Extract from Potentilla chinensis as Cosmeceutical Material (화장품 소재로써의 딱지꽃(Potentilla chinensis) 뿌리 추출물의 효과)

  • You, Jae Chon;Jung, Hae Soo;Kim, Hyoung Shik;Lee, Jeong Hun;Moh, Sang Hyun
    • Journal of Applied Biological Chemistry
    • /
    • v.59 no.1
    • /
    • pp.13-17
    • /
    • 2016
  • As natural plant-based industry has been expanded, the use of oriental medicinal plants as cosmeceutical material received a lot of attentions in the cosmetic industry. Among various medicinal plants, Potentilla chinensis have drawn interests for its biological effects. Although several attempts were tried to study its biological effect as medicinal plant, only limited results were reported to evaluate its biological effect as cosmeceutical material. In this study, we examined the possibility of root extract from Potentilla chinensis as a cosmeceutical material because the root part has been reported to have several kinds of health promoting effects. After extraction of roots, biological evaluation including anti-inflammation, anti-wrinkle, whitening effect and moisturizing effect was performed. As a result, the root extract showed remarkable biological activities through stimulating synthesis of elastin and aquaporin-3, and inhibiting melanin synthesis, cyclooxygenase-2 expression and expression of metallopeptidase-1.

Genotoxicological safety of the Gamma-Irradiated Medicinal Herbs in the Micronucleus Test Using CHO Cells In Vitro (CHO 세포에서의 소핵시험을 이용한 감마선조사 생약재의 안전성에 관한 유전독성학적 평가)

  • 조성기
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.26 no.5
    • /
    • pp.952-957
    • /
    • 1997
  • The three medicinal herbs-Curcuman longa Linne, Paeonia japonica Miyabe, Scutellaria baikalensis George-irradiated with gamma rays were tested for their possible genotoxicity. The methanol-soluble and water-soluble fractions of the 10kGy gamma-irradiated herbs were examined in cultured Chinese hamster ovary(CHO) cells for their ability to induce micronuclei. No mutagenicity of each test material was detected in the assay with or without metabolic activation. The safety of the herbs irradiated with gamma rays at practical doses needs further investigations using in vivo genotoxicity and chronic and reproductive toxicity tests.

  • PDF

Selection and Control Effect of Environmental Friendly Organic Materials for Controlling the Ginseng Alternaria Blight (인삼에 발생하는 점무늬병의 친환경적 방제를 위한 유기농업자재 선발 및 기 선발된 자재의 효과시험)

  • Kim, Woo Sik;Park, Jee Sung
    • Korean Journal of Medicinal Crop Science
    • /
    • v.21 no.5
    • /
    • pp.388-393
    • /
    • 2013
  • This study was conducted to select environmental friendly organic materials for controlling the ginseng alternaria blight and to evaluate their effects from 2011 to 2012. Alternaria blight is caused by Alternaria panax and is the most common ginseng disease in Korea. Environmental friendly organic materials were used to reduce amount of chemical fungicides and the number of spray for control of Ginseng Alternaria leaf blight. In 4 years of ginseng, control value of Alternaria leaf blight by single application of Defenoconazole WP was 82.3% and those of single application was 62.0~75.9%. Consequently, mixed or alternated application of eco-material products could be recommended as a control method to reduce the amount of fungicides.

Inhibitory Effect of White Ginseng Fraction on Skin Pigmentation (피부에서의 백삼 분획물의 멜라닌 색소 저해효과)

  • Jo, Youn-Ock;Kong, Yeon-Hee;Lee, Young-Chul;Kim, Sung-Soo;Choi, Sang-Yoon
    • Korean Journal of Medicinal Crop Science
    • /
    • v.16 no.3
    • /
    • pp.192-194
    • /
    • 2008
  • In our previous study, ethylacetate fraction of white ginseng (root of Panax ginseng C.A. Meyer) extract inhibited mushroom tyrosinase activity and melanin production in melanocytes. This study examined its effects on the expression of melanin biosynthesis-related enzymes to explore the depigmenting pathway. Moreover, depigmenting effect on animal skin was examined using UV-B induced hyperpigmented skin of brown guinea pigs. The ethylacetate fraction of the white ginseng extract exhibited depigmenting activity in the skin of brown guinea pig without visible edema. In addition, this fraction reduced tyrosinase expression in melanocytes. The results suggested that ethylacetate fraction of white ginseng extract might be used as skin depigmenting material by inhibition of tyrosinase activity and expression.

Effects of Root Diameter and Peeling Methods on Drying Time and Paeoniflorin Content of Paeonia Lactiflora Pallas (작약(芍藥)의 뿌리굵기와 각피(刻皮)정도가 건조시간 및 품질에 미치는 영향)

  • Kim, Ki-Jae;Park, Chun-Hong;You, Oh-Jong;Shin, Jong-Hee;Park, So-Deuk;Choi, Boo-Sull
    • Korean Journal of Medicinal Crop Science
    • /
    • v.6 no.1
    • /
    • pp.38-43
    • /
    • 1998
  • This experiment was carried out to gather basic information for improvement of peeling methods in peony (Paeonia lactiflora) roots which have been used for medicinal resources in Korea. Drying time required was shortened in thin root. Optimum drying time after machine peeling appeared to be 20 hrs in 5 to 10mm of root diameter, 39 hrs in 10 to 15mm, 48 hrs in 15 to 20mm, 56 hrs in more than 20mm, but those of unpeeled roots took 11 hrs in 5mm of root diameter and 4 hrs in exposed parent material. Paeoniflorin content in dried roots after peeling was lower than that of unpeeled root. Paeoniflorin content in root below 5mm in diameter was highest (6.15 %) and that was decreased in the increased root diameter up to 20mm, but it was slightly increased in root greater than 20mm in diameter.

  • PDF

Selection and Technical Development for Seed Pelleting Material of Codonopsis lanceolata Trautv (더덕 종자의 펠렛팅을 위한 소재 탐색 및 기술개발)

  • Choi, Kyeong-Gu;Lee, Youn-Su;Cha, Kwang-Ho
    • Korean Journal of Medicinal Crop Science
    • /
    • v.14 no.3
    • /
    • pp.130-133
    • /
    • 2006
  • This study was conducted to select Codonopsis lanceolata seed's new pelleting particulate materials and adhesives. Different adhesives (Polyvinyl alcohol (PVA), Carboxymethyl cellulose (CMC), Polyvinyl pyrrolidone (PVP), Xanthan gum (XG), Arabic gum (AG)) and particulate materials (Illite, Diatomite, Pyrophyllite + Illite + Diatomite (PID), Pyrophyllite + Illite + Talc (PIT), Bentonite + Talc (BT)) were tested for seed pelleting. PID for Codonopsis lanceolata seed pelleting appeared to be the best particulate material. Among the pelleting adhesives, PVP was the best adhesive for seed pelleting, and the optimum concentration for germination of pelleting seed was 1 %. Germination rate of the pelleted seeds treated with PID particulate material and PVP adhesive was higher (86.8%) than those of raw seeds (85.5%). $T_{50}$ and MDG of pelleted Codonopsis lanceolata seed required five and eight days at soil moisture content of 50%, respectively.

Enhancement of Antioxidant Activities and Whitening Effect of Acer mono Sap Through Nano Encapsulation Processes (고로쇠 수액 나노입자의 항산화 활성 및 미백 효과의 증진)

  • Kim, Ji-Seon;Seo, Yong-Chang;Choi, Woon-Yong;Kim, Hack-Soo;Kim, Bo-Hyeon;Shin, Dae-Hyeon;Yoon, Chang-Soon;Lim, Hye-Won;Ahn, Ju-Hee;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
    • /
    • v.19 no.3
    • /
    • pp.191-197
    • /
    • 2011
  • In this study, we investigated antioxidant activities and whitening effects of Acer mono sap by encapsulation of nanoparticles. Acer mono sap was through ultra high pressure process and then encapsulated by lecithin. Nano-encapsulated The nanoparticles of Acer mono sap showed highest free radical scavengering effect as 89.7% in adding sample (1.0 mg/ml), compared to sap of non-encapsulation. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 47.8%. High inhibitory of tyrosinase was also measured as 85.8% by adding lecithin nano-particle of 1.0 mg/ml. The nano-particles also showed 14.8% of low cytotoxicity against human normal fibroblast cells in adding 1.0 mg/ml of the highest concentration. These results indicate that Acer mono sap may be a source of cosmetic agents capable of improving whitening effect and antioxidant activites.