• Proceedings of the Korean Society for Information Management Conference
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• 2002.08a
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• pp.279-286
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• 2002

미래의 정보시스템에서는 온토로지가 핵심적인 역할을 할 것이다. 최근 의학분야에서도 임상의 지식관리와 의학정보검색의 효율화를 위해 온토로지에 대한 연구가 많이 이루어지고 있다. 본 연구는 의학 분야에서 개발된 온토로지를 비교 분석하여 특징을 파악하고 의학정보시스템의 활성화를 위한 온토로지 구축의 방향을 제시하고자 하였다.

• Journal of Korean Medical classics
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• v.25 no.4
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• pp.105-113
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• 2012

Objectives : Acquiring information from symptoms is one of the important method to gain clinically available information in korean medicine. Therefore, up to now, study of symptom terms was frequently implemented in promotion of various information project. In data extraction methods using symptom information from DB, information search using synonym and method using ontology is studied and utilized. However, considering concept of symptom has essential information of appeared body area and phenomenon we think that extending synonym and ontology relationship in symptom terms can be useful for search and set to this study. Methods : We collect terms relevant to human body area and structure described in Donguibogam. Synonymous relationship between collected terms is organized. Relationship between collected terms is build to human-body-knowledge table which has form of Concept+Relation+Concept. Type of relationship is limited on a range of expressing content about parts of human body. Result & Conclusion : Search condition is generated automatically using relationship of the upper area in knowledge table contents. Information of next and previous acupuncture point, upper and lower acupuncture point, left and right acupuncture point can be searched using information of acupuncture point location, order, relative position in area, direction in knowledge table contents.

• Journal of Korean Medical classics
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• v.19 no.1 s.32
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• pp.155-167
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• 2006

From th Study on A Study on the Thesaurus of Korean medical information for developing search engine, the conclusion is as follow. Knowledge based information system consists of concepts, facts and relation. The final goal of developing the Knowledge based information system is to select, store and control the knowledge and information of Oriental Medicine. Considering limitation of organizing the knowledge system, it is difficult to realize complete basic system and application method. In order to work, it is necessary to combine experts in each part, for example Domain experts, Information and Knowledge engineer. Through the development of knowledge based information system, we can construct EMR(Electronic Medical Record) system in the near future, and it is possible to make semi-expert system. To make Knowledge based information system, we need to establish standards of information that make the distribution of Knowledge and information easily.

• Journal of Korea Society of Industrial Information Systems
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• v.17 no.6
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• pp.31-40
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• 2012

Ubiquitous technology influences on various firms of contents needed for self-healthcare, as it fuses into medical services. Particularly, rapid changes in the web and mobile environment, requiring various sorts of healthcare and its related contents, make efficiency of search more important. Personalized contents needs to be more refined as well as the existing simple keyword-centered searching method needs to be more effective in order to meet both requirements and characteristics of each patient or each user. A precise semantic searching method is required for a system to understand promptly the meaning of a contents. In this respect, to build a healthcare ontology has its own significance. This study builds up a system model that can be utilized practically in existing systems by setting up the Food Class and its sub-class among the healthcare contents with Protege tool and then materializing constraints and its relationships between each class. The healthcare contents ontology provides patients or users with a platform which can search the needed information promptly and precisely.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.11
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• pp.443-450
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• 2018

Crohn's disease, which is recently increasing in Korea, may be seen throughout the gastrointestinal tract and cause various symptoms. In particular, Crohn's disease is especially difficult to diagnose with several symptoms similar to other ulcerative colonic diseases. Thus, some studies are underway to distinguish two or more similar diseases. However, the previous studies have not described the procedural diagnosis process of it, which may lead to over-examination in the process. Therefore, we propose a diagnosis process of Crohn's disease based on the analysis of redundancy, sequential linkage and decision point in the diagnosis of Crohn's disease, so that it enables to identify ulcerative colonic diseases with symptoms similar to Crohn's disease. Finally, we can distinguish the colon diseases that have symptoms similar to Crohn's disease and help diagnose Crohn's disease effectively by defining the proposed process-oriented association as an ontology. Applying the proposed ontology to 5 cases showed that more accurate diagnosis was possible and in one case it could be diagnosed even with fewer tests.

• Proceedings of the Korean Information Science Society Conference
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• 2011.06c
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• pp.96-97
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• 2011

Heterogeneity in different Health Information Systems (HIS) processes persists to be the most demanded problem to be resolved in healthcare domain. The only way to resolve this problem is to practice health standards. One of such standards is Health Level Seven (HL7), used for the communication of medical information between healthcare systems. HL7 V3 has the aim to support all healthcare workflows. It defines series of electronic messages called interactions to support healthcare workflows. These interactions are part of the Interaction Model. Different healthcare organizations can conform to different process workflows based on their requirements. The heterogeneity in workflows results in communication blockade between sender and receiver healthcare organizations. We propose Interaction Ontology in order to cater the heterogeneity in workflows and provide process interoperability.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.834-841
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• 2012

We in this paper propose a mobile application for supporting medical treatment based on Korean medicine ontology. It has three processes for treating patients. First, after a pattern is decided for patient' symptoms, a formula for the pattern is selected and medicinal materials constituting the formula is added or removed. Second, formulas are searched and prescribed for patient's symptoms without the process of the pattern decision. Third, after medicinal materials are searched for patient's symptoms, formulas consisting of the medicinal materials are prescribed. Our application aims to help korean medicine doctors treat patients through providing decision supporting functions such as the recommendation of symptoms of diseases accompanying patient's symptom. Doctors generally diagnosis patients according to their experiences and knowledges. Nevertheless, our application can help them, providing diverse forms of information that they may miss in the medical treatment.

• Journal of Korean Medical classics
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• v.32 no.1
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• pp.133-143
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• 2019

Objectives : In this study, we analyze the medical significance of feces symptoms so that the daily records of the feces of individuals can be not only used as a measure of individual health monitoring in daily life, but also more actively connected to the medical treatment of the Korean Medicine (KM). Methods : Categories and clinically significant attributes for symptoms of Urination and defecation in the KM ontology DB are determined, and connected to KM related dialectical indicators by experts' common criteria including Viscera and Bowels [臟腑], eight principles [八綱], Qi Blood fluid and humor phlegm-retained fluid static blood [氣血津液痰飮瘀血], six excesses [六淫]. Results : The analysis of the symptoms of feces in the Korea Medicine ontology shows that the symptoms of stool in categories of 'stool stiffness', 'blood swelling', 'discomfort' are highly ranked among the overall clinical symptom categories. In the case of urine symptoms, symptoms corresponding to 'urine color,' 'urine discomfort,' and 'urine volume' are the top rankers among other total clinical symptoms. In the case of stool, the relationship between the symptom of stool and the categories of spleen, stomach, and colon is increased as the weighted symptom is considered. The relationship between the symptom of urine and the categories of the small intestine and the bladder is increased in the same way. Conclusions : This study could help better utilize the personal generated health records of feces in clinical practice of Korean Medicine.

• Journal of Information Processing Systems
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• v.12 no.4
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• pp.741-753
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• 2016

In the medical fields, many efforts have been made to develop and improve Hospital Information System (HIS) including Electronic Medical Record (EMR), Order Communication System (OCS), and Picture Archiving and Communication System (PACS). However, materials generated and used in medical fields have various types and forms. The current HISs separately store and manage them by different systems, even though they relate to each other and contain redundant data. These systems are not helpful particularly in emergency where medical experts cannot check all of clinical materials in the golden time. Therefore, in this paper, we propose a process to build an integrated data model for medical information currently stored in various HISs. The proposed data model integrates vast information by focusing on medical images since they are most important materials for the diagnosis and treatment. Moreover, the model is disease-specific to consider that medical information and clinical materials including images are different by diseases. Two case studies show the feasibility and the usefulness of our proposed data model by building models about two diseases, acute myocardial infarction (AMI) and ischemic stroke.

• Parasites, Hosts and Diseases
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• v.57 no.5
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• pp.489-497
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• 2019

Cystic echinococcosis (CE), a zoonotic disease caused by Echinococcus granulosus at the larval stage, predominantly develops in the liver and lungs of intermediate hosts and eventually results in organ malfunction or even death. The interaction between E. granulosus and human body is incompletely understood. Exosomes are nanosized particles ubiquitously present in human body fluids. Exosomes carry biomolecules that facilitate communication between cells. To the best of our knowledge, the role of exosomes in patients with CE is not reported. Here, we isolated exosomes from the sera of patients with CE (CE-exo) and healthy donors and subjected them to liquid chromatography-tandem mass spectrometry analysis. Proteomic analysis identified 49 proteins specifically expressed in CE-exo, including 4 proteins of parasitic origin. The most valuable parasitic proteins included tubulin alpha-1C chain and histone H4. And 8 proteins were differentially regulated in CE-exo (fold change>1.5), as analyzed with bioinformatic methods such as annotation and functional enrichment analyses. These findings may improve our understanding about the interaction between E. granulosus and human body, and may contribute to the diagnosis and prevention of CE.