• 한국산학기술학회논문지
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• 제10권2호
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• pp.438-446
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• 2009

본 연구는 급성골수성백혈병의 우선적인 치료방법인 항암화학치료제 투여 후 발생되는 호중구 감소기간을 잘 관리하기 위하여 호중구감소증 정도와 영양상태와의 관련성을 규명한 서술적 조사연구이다. 본 연구는 B시 P대학병원에서 1차 강화항암화학치료까지 받고 회복한 성인환자 54명의 환자의 의무기록지를 열람하여 조사하였다. 연구결과, 항암화학요법 주기내의 호중구감소증이 지속되는 기간은 6일에서 28일(평균 14.78일)이었으며, 호중구감소증이 시작되는 시기는 5일째에서 15일째 사이(평균 9.54일)에 나타났으며, 최저백혈구수의 시기는 평균 18.41일째였으며, 27.8%에서 19일째 가장 적은 백혈구수를 보였다. 항암요법 주기내의 항암화학요법 시작시와 절대호중구수가 가장 낮은 시기의 총단백질량, 체중, 체질량지수와 같은 영양상태 변화는 거의 없었으며, 알부민, 콜레스테롤은 유의하게 감소하였다. 대상자의 일반적인 특성에 따른 호중구감소증은 성별, 나이, 동반질환유무, 체표면적에 따른 차이가 없었다. 호중구감소증과 영양상태간의 상관관계는 없었으나, 급성골수성백혈병 환자의 호중구감소 기간 동안의 영양상태에 대한 정보는 제공해 줄 수 있을 것으로 기대된다.

• 한국식생활문화학회지
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• 제30권4호
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• pp.395-405
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• 2015

Insamsokmieum (人蔘粟米飮), which is a kind of water gruels made with millet, ginseng, glutinous rice, and some minor ingredients, was frequently used as a medicinal food for the royal family, and it appeared first at the 10th year of King Sukjong's reign. We investigated Insamsokmieum through a literature review and the "SeungjeongwonIlgi(承政院日記)" of King Sukjong (肅宗) from his 1st year (1674) to 46th year (1720). We analyzed the nutritional value and efficacy of Insamsokmieum. In Oriental medicine, Insamsokmieum is prescribed mainly to treat symptoms such as nausea, languidness, and exhaustion in King Sukjong and Queen Inhyun (仁顯王后). In nutritional terms, Insamsokmieum has higher nutrition density than that of rice porridges (白粥) and has relatively high vitamin and mineral contents. Some nutrients such as leucine and glutamic acid, which are contained in the millet, are also known to help alleviate these symptoms. Whereas there have been studies on the efficacy and types of diet during the Joseon Dynasty, studies regarding nutrition characteristics are lacking. This study will demonstrate the superiority of dietary treatments of the Joseon Dynasty and their potential for application to modern nutrition.

• 대한약침학회지
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• 제18권1호
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• pp.27-35
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• 2015

Objectives: In Korea, cancer is one of the most important causes of death. Cancer patients have sought alternative methods, like complementary and alternative medicine (CAM) together with Western medicine, to treat cancer. Also, there are many kinds of providers of CAM therapy, including providers of Korean oriental medicine therapy. The purpose of this study is to identify the behaviors of Korean oriental medicine therapy and CAM therapy providers who treat cancer patients and to provide background knowledge for establishing a new policy with the management and quality control of CAM. Methods: Structured and well organized questionnaires were made, and 350 persons were surveyed concerning the providers of CAM or Korean oriental medicine. The questionnaires were collected and analyzed. Results: The questionnaires (182) were collected. The questionnaires identified a total of 73 known providers, such as medicinal professionals or other providers of CAM suppliers, 35.6% of whom had had experience with treating cancer patients (52.6% vs. 29.6%). The treatment methods were a little different: alternative therapy and nutritional therapy being preferred by medicinal professionals and mind body modulation therapy and alternative therapy being preferred by other CAM providers. Four patients (7.4%) experienced side effects, and 6 patients (12.5%) experienced legal problems. As the method for managing the therapy, CAM providers, medicinal professionals, and other CAM providers had different viewpoints. For example, some CAM providers stated that both legislation and an official education on CAM or a national examination were needed as a first step to establish the provider's qualifications and that as a second step, a license test was needed for quality control. To the contrary, medicinal professionals stated that a license test was needed before legislation. Conclusion: Adequate management and quality control of CAM providers is thought to involve both education and legislation.

• 성인간호학회지
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• 제26권2호
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• pp.159-170
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• 2014

Purpose: This research investigated the degree and predictors of hot flashes and hypogonadism symptoms in patients with prostate cancer receiving hormone replacement therapy. Methods: The subjects were 111 patients with prostate cancer receiving hormone replacement therapy in two university hospitals located in D city. The measurement tools included Hot Flash Diary and AMS (Aging Male's Symptoms rating scales). The data were analyzed using t-test, ANOVA, and binary logistic regression analysis. Results: The percentage of patients who experienced hot flashes among the participants was 14.4%. The predictors for hot flashes were eating irregularly, having coffee frequently and the types of hormone. The average score of hypogonadism symptom was 2.16 out of five-point scale and the highest score of hypogonadism symptom was the sexual symptoms (2.77 out of five-point scale). The predictors for hypogonadism symptom were eating habits and years of having the illness. Conclusion: These findings provide the information that irregularly eating habit was an important factor in hot flashes and hypogonadism symptoms of the participants. Therefore the development of a nutritional education encouraging regular meals is necessary for the given population.

• 재활간호학회지
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• 제3권2호
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• pp.212-227
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• 2000

The purpose of this study was to investigate the patterns of alternative therapy and to describe the characteristics of cancer patients used alternative therapy. The sample of this study were 232 consisted of cancer patients who visited at Pusan National University Hospital, Dong-a, Kosin University Hospital. The data were gathered from August, 1 to October, 30 1999 and analyzed by using SPSSWIN program for frequency, percentile and $X^2$-test. The important results of this study are as follows. 1. In population-sociological characteristics, sexual distribution showed female 52.6%, and the male 47.4%, age distribution showed that more than 60year old group are most as 31.5%. 2. In the disease characteristics, colon and rectal cancer patients were most as 19.0%. In the type of pain, the most of subjects were "dully pain" as 25.4%. In the pain level, 134 subjects complained pain, mean maximal pain score was $7.3{\pm}2.29$ in 10 points rating scale. 3. 132 patients (56.9%) among 232 cancer patients had used alternative therapy. The most common type of alternative therapy was dietary and nutritional therapy 44%, the place of use. home 43.2%, duration, less than 3 months, 56.8%. The most common motive was a recommendation by friends or family. The degree of satisfaction after the use of alternative therapy was high for 22.0%. 4. In the relation between general characteristic and utilization of alternative therapy, the only living area was showed a significant statistical differance($X^2$ = 4.070, P= .044). also in the relation between disease characteristic and utilization of alternative therapy, morbidity periods, the size of higher pain, the type of treatment were showed a significant statistical differance($X^2$= 7.964, 7.303, 3.565, P=.044, .026, .042). In conclusions, these findings indicate that cancer patients use various complementary and in alternative therapy. therefore, suggested that medical doctors or nurses verify the true effects or side-effects from the most common complementary or alternative therapies through experiments.

• 가정간호학회지
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• 제14권1호
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• pp.31-41
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• 2007

Purpose: This study was designed to evaluate the effect of home care nursing intervention with parenteral hydration and IV anti-emetic therapy on distress, nutritional status, anxiety, depression and QOL in gynecologic cancer patients who were undergoing combination chemotherapy. Methods: Quasi-experimental design was used to test the intervention. Changes of result variables were measured to evaluate effects of the intervention. variables consisted of serum lab results(auto analytic equipment for lab), symptom distress Scale(McCorkle & Young, 1978; Song et al., 2000), nutritional status(body weight, circumference of upper arm, serum protein, serum albumin, oral intake per day), anxiety(Spielberger, 1972; Kim & Shin, 1978), depression(Zung, 1965; Kim, 1995) and QOL(Padilla et al., 1983; Lee & Jo, 1996). Subjects were selected among gynecologic cancer patients(EG 15 patients and CG 15 patients) by convenient sampling. Data collection was done from June to Nov. in 2000. Data were analyzed by Chi-test and Mann-whitney U test using SPSS Win 10.0. Result: Hypothesis 1, the EG receiving this intervention equals to lab test(Hb & ANC, GOT & GPT, BUN & Cr) the CG, was supported(u=69.50 p=.074; u=94.50, p= .455; u= 89.50, p= .339; u=106.50, p= .803; u=75.00, p= .119; u=97.50, p= .523). Hypothesis 2, the EG has less symptom distress than the CG, was also supported(u=43.50, p= .004). Hypothesis 3, the EG has higher nutritional status than the CG, was partially supported on daily oral intake (u=59.00, p= .025). Hypothesis 4, the EG has less anxiety than the CG, was rejected(u=86.50, p= .280). Hypothesis 5, the EG has less depression than the CG, was rejected(u=203.50, p= .228). and the last hypothesis 6, the EG has higher QOL than the CG was supported (u=51.50, p= .011). Conclusion: Home care nursing intervention undergone in this study was found to be effective to reduce patients' symptom distress and to improve their oral intake and QOL.

• Nutrition Research and Practice
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• 제9권2호
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• pp.186-191
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• 2015

BACKGROUND/OBJECTIVES: Rheumatoid arthritis (RA) is associated with an excess mortality from cardiovascular disease which is likely attributed to an atherogenic lipid profile. Among nutritional factors vitamin K has been recently focused as a pivotal nutrient in improvement of lipid related markers. Thus, this study was designed to determine the effects of vitamin K on lipid profile in this disease. SUBJECTS/METHODS: Fifty eight patients with definitive RA were participated in the present double blind placebo controlled study. They were randomly allocated into two groups to receive vitamin $K_1$ as phylloquinone [10 mg/day] (n = 30) or placebo pills (n = 28), for eight weeks. In order to control the effects of probable confounders dietary intakes, anthropometric measurements including weight and height, clinical status using disease activity score-28 (DAS-28), physical activity and anxiety status were evaluated at baseline. Moreover, serum levels of lipid related markers including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) were measured at baseline and at the end of intervention. RESULTS: There were no significant differences between the two groups regarding any of the baseline characteristics. After adjusting for some relevant confounders, in comparison between two groups, we observed no significant changes in lipid related markers at the end of intervention. Also, there was no significant difference between before and after intervention values within groups (P > 0.05). CONCLUSIONS: Function of vitamin $K_1$ in lipid profile modification remains still controversial. This study showed that vitamin $K_1$ has no effect on lipid profile in women with rheumatoid arthritis. Further studies with a longer follow-up are required to determine the effects of vitamin K on atherogenic lipid profile.

• 대한영양사협회학술지
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• 제18권1호
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• pp.16-29
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• 2012

The purpose of this study was to investigate the changes in nutritional status of gastrectomy patients. The anthropometric and biochemical data were measured at pre-operation, at discharge, 1 month after discharge, and 3 months after discharge. Nutrient intake levels, nutrients adequacy ratio (NAR), mean adequacy ratio (MAR), and the proportion of patients with intake levels inferior to those of dietary reference intakes (DRIs) were analyzed at discharge, 1 month after discharge, and 3 months after discharge. Finally, the data on 23 patients (15 male and 8 female) were collected and used for statistical analysis. Fifteen patients underwent subtotal gastrectomy, and 8 patients underwent total gastrectomy. Compared to pre-operation, body weight and body mass index of subjects significantly decreased at discharge, 1 month after discharge, and 3 months after discharge (P<0.001). Serum albumin (P<0.001), total lympocyte count (P<0.001), total cholesterol (P<0.001), hemoglobin (P<0.001), hematocrit (P<0.001), and mean corpuscular hemoglobin concentration (P<0.05) were significantly different between pre-operation, at discharge, 1 month after discharge, and 3 months after discharge. The proportions of patients with lower nutrient intake levels than DRIs were substantial. MAR at discharge, 1 month after discharge, and 3 months after discharge were 0.70, 0.80 and 0.91, respectively. Especially, the NARs of folate, niacin, vitamin $B_2$, vitamin C, and zinc were all low. Considering the various nutritional problems of gastrectomy patients, systematic medical nutrition therapy is needed after gastrectomy.

• 대한영양사협회학술지
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• 제7권1호
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• pp.87-104
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• 2001

This study was conducted as a part of the project developing the standards of national board test for the dietitian's licence. The purpose of this study was to define the job description of dietitians, and to describe the task elements based on the detailed analysis of the dietitians' work. This study team established the research team which was composed of food and nutrition experts, 7 of registered dietitians and 3 of university professors. Draft job description form was made to fully explain the dietitians' task elements, process and sequence by the research team. Final job description form was confirmed after the validity of 576 task elements was reevaluated upon 4 point scale test based on the frequency, importance, and difficulty by 21 field registered dietitian by the study team. It was also confirmed by the university. This form was formated by following DACUM method which analyzed the job description containing duty, task and task elements. It was organized to include every dietitians' work and to describe the every detailed process of work. Duty was defined as the specific and independent work as a dietitian, and was composed of 17 parts, i.e 10 parts in food supply management area and 6 parts in nutritional care service area and self promotion area. Duties were also divided into 99 tasks containing the 576 detailed task elements to describe definite action, steps and decisions. Seventeen parts are following; menu planning, storage and inventory control, food production, meal service, waste management, sanitation, equipment and facility management, human resource management, financial management, nutrition assessment of life cycle, nutritional assessment of several disease, nutritional assessment in specific condition, medical nutrition therapy, nutritional education, public health nutrition and self promotion. If these protocols are properly performed and presented, they can provide the likelihood that dietetics professionals work as a primary contributors in promoting health care and preventing disease nationally.

• 여성건강간호학회지
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• 제11권3호
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• pp.193-201
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• 2005

Purpose: The purpose of this study was to describe the use pattern of alternative therapies in middle aged women. Method: The subjects of this study were 530 women from 40 to 64 years of age. The data of this study was patients' records. The data was gathered from April 1st, 2004 to June 30th, 2004. Data was analyzed statistically by using the SPSS/WIN 10.0 program. Result: It was shown that 63.5% of the subjects have utilized one or more types of alternative therapy. The most common type of alternative therapy was dietary and nutritional therapy 38.3%, and the place of use was the home 64.1%. The most common reason was a recommendation by friends. The degree of satisfaction after the use of alternative therapy was 95.2%. Among users of alternative therapies, the most frequent responses to each question were as follows; Motive of Use- "for health maintenance and promotion." (62.7%) In the relation ship between general characteristics and utilization of alternative therapy, religion(x2=12.33, p=.02), exercise(x2=8.21, p=.004), and health status(x2=14.95, p=.005) showed a significant statistical difference. Conclusion: We found that middle aged women used alternative therapies more frequently than other populations. Therefore, it is suggested that medical doctors or nurses verify the true effects or side-effects from the most therapies or nurses verify the true effects or side-effects from the most common complementary or alternative therapies through experiments.