• Journal of Korean Neurosurgical Society
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• v.54 no.2
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• pp.107-111
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• 2013

Objective : We investigated the effectiveness of stereotactic gamma knife Radiosurgery (GKR) for radioresistant brain metastases with the impact upon histology. Methods : Between April 2004 and May 2011, a total of 23 patients underwent GKR for 67 metastatic brain tumors from 12 renal cell cancers, 5 sarcomas and 6 melanomas. The mean age was 56 years (range, 18 to 79 years). Most of the patients were classified as the Radiation Therapy Oncology Group recursive partitioning analysis class II (91.3%). The synchronous metastasis was found in 6 patients (26.1%) and metachronous metastasis in 17 patients (73.9%). We analyzed the local control rate, intracranial progression-free survival (PFS) and overall survival (OS). Results : The mean tumor volume for GKR was 2.24 cc and the mean prescription dose was 19.4 Gy (range, 10 to 24) to the tumor margin. Out of metachronous metastases, the median duration to intracranial metastasis was 3.3 years in renal cell cancer (RCC), 2.4 years in melanoma and 1.1 years in sarcoma (p=0.012). The total local control rate was 89.6% during the mean 12.4 months follow-up. The six-month and one-year local control rate was 90.2% and 83% respectively. Depending on the pathology, the control rate of RCC was 95.7%, sarcoma 91.3% and melanoma 80.5% during the follow-up. The common cause of local failure was the tumor bleeding in melanoma. The median PFS and OS were 5.2 and 8.4 months in RCC patients, 6.5 and 9.8 months in sarcoma, and 3.8 and 5.1 months in melanoma. Conclusion : The GKR can be one of the effective management options for the intracranial metastatic tumors from the radioresistant tumors. The melanoma showed a poor local control rate compared to other pathologies because of the hemorrhage.

• Journal of Korean Medicine for Obesity Research
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• v.18 no.1
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• pp.1-9
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• 2018

Objectives: The objective of this study was to assess the safety of 'Gamitaeeumjowee-tang' by analyzing adverse events in weight loss program in combination with 'Gamitaeeumjowee-tang' and low-calorie diet. Methods: A retrospective review of adverse events in weight loss program in combination with 'Gamitaeeumjowee-tang' and low-calorie diet from the electronic medical chart (n=124) between June 2015 and December 2016 was conducted. Three Korean Medicine Doctors (KMDs) reviewed adverse events for two times, during week 2 to 4 and at week 10, after starting weight loss program. Adverse events were evaluated in terms of causality, severity and system-organ classes. Also, agreement among the three KMDs was made through further discussion in case of disagreement after independent review. Results: The overall rate of adverse events was 37.1% during week 2 to 4 and 16.9% at week 10. For causality of adverse events using the World Health Organization-Uppsala Monitoring Centre causality categories, 52.2% were evaluated 'possible' at week 2-4 and 57.1% were evaluated 'unlikely' at week 10. All symptoms were evaluated as 'mild' by LDS scale. Nausea (15, 12.1%) was the most frequent adverse event at week 2-4 and dizziness (6, 4.8%) was the most common at week 10. Conclusions: Adverse events decreased over time. There were no serious adverse events and none of the subjects were dropped due to adverse events. Continuous study is needed to prove the safety of 'Gamitaeeumjowee-tang' for treating obesity.

• Journal of Acupuncture Research
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• v.26 no.6
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• pp.133-140
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• 2009

Objectives : Miso facial rejuvenation acupuncture is a Korean medical treatment technique for face lifting. The authors aimed to evaluate the effects of Miso facial rejuvenation acupuncture on facial skin furrows. Methods : 11 patients who made first visits to Hyo-Jun Korean Medical Clinic from October 1, 2009 to October 25, 2009 were each given one-time treatment of Miso facial rejuvenation acupuncture treatment. A portable fluorescent dermal diagnostic equipment, ECOSKIN, was used to measure extraocular skin furrows and perioral skin furrows width and depth before and after treatment. Results : Mean width and depth of both the extraocular and perioral skin furrows decreased after one-time Miso facial rejuvenation acupuncture treatment. Extraocular skin furrow width, depth, and perioral skin furrow width showed statistically significant decreases(p=0.003, 0.017, 0.041 respectively). Conclusions : Mean depth and width of both the extraocular and perioral skin furrows decreased after receiving Miso facial rejuvenation acupuncture treatment. Miso facial rejuvenation acupuncture may be an effective treatment for improving wrinkles in clinic.

• Tuberculosis and Respiratory Diseases
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• v.63 no.5
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• pp.449-453
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• 2007

Totally implanted central venous access devices for chemotherapy (chemoport) are being used increasingly in lung cancer patients. Vascular catheters are associated with various complications including infection, thrombosis as well as spontaneous fractures and embolization of the catheter, which is known as 'pinch-off syndrome'. 'Pinch-off syndrome' refers to the compression of a subclavian central venous catheter between the clavicle and first rib resulting in an intermittent or permanent obstruction, which can lead to tears, transection, or embolization. We report two cases of fractured and embolized implanted subclavian venous catheters in which the fragments were removed percutaneously. A 62-year-old man presented with back pain with a duration of a few weeks. The chest radiograph revealed complete transsection and embolization of the catheter into the right atrium. In addition, a 47-year-old woman with a chemoport had a grade 3 pinch-off sign in a chest radiograph demonstrating complete transsection and embolization of the catheter into the pulmonary artery. Both cases were managed by retrieving the embolized distal fragment percutaneously and removing the proximal section of the catheter.

• The Korean Nurse
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• v.5 no.4 s.24
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• pp.68-75
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• 1966

The status of visits and deliveries on 1218 expectant mothers who registered at prenatal clinic, maternal and child health centerm Chonnam University Hospital, during Jan. 1958 to Dec. 1965 has been studied, and the following result were obtaind: 1. The m

• 대한핵의학회:학술대회논문집
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• 1970.10a
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• pp.87.2-88
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• 1970

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.28 no.1
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• pp.152-159
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• 2015

Purpose : This rearch aims to prove effects of an oriental medical complex therapy on vitiligo patients who have the symptoms in the hands. Method : The rearch conducted its investigation targeting these four patients who have the symptoms in the hands. The study resolved the findings through the comparison on the pictures before and after the therapy. Result : After making a comparison on the pictures, the study confirmed positive changes in the conditions of the patients. The oriental medical complex therapy turned out to be effective enough to treat the patients who have the symptoms in the hands. Conclusion : Such result leads the study to a conclusion that the oriental medical complex therapy can be an effective method to treat these patients who have the symptoms in the hands. In addition, more case studies and research will be necessary.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1885-1887
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• 2014

Skin metastases of breast cancer are usually late events in the course of tumor progression and signify a poor prognosis. They may remain as a therapeutic challenge especially after failure of standard treatments. Topical interventions, together with or without radiotherapy, may only palliate the symptoms temporarily. However, there may be alternative treatment modalities for unresectable breast cancer skin metastases resistant to chemotherapy and radiotherapy. There are various genetic alterations in tumors and therapeutic potential of expression patterns for factors like epidermal growth factor receptor may have important clinical implications in case of disease refractory to the conventional treatments. Here, we clarified the therapeutic options and genetic alterations in skin metastatic breast cancer patients refractory to standard chemotherapeutics.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.3
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• pp.249-258
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• 2016

Objectives : The purpose of this study is to report the effectiveness of Hyeongbangdojok-san on 4 seborrheic dermatitis patients who were diagnosed as Soyangin.Methods : 4 seborrheic dermatitis patients were treated by Hyeongbangdojok-san. The effect of treatment was measured by EASI score, VAS score, photographs.Results : EASI score and VAS score decreased as a result of Hyeongbangdojok-san treatment in 4 patients.Conclusions : These case-studies showed an efficient result of using Hyeongbangdojok-san in the seborrheic dermatitis of Soyangin. And an author consider that continuous clinical study will be needed in Korean medical dermatology.

• Korean Journal of Oriental Medicine
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• v.13 no.3
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• pp.53-67
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• 2007

Seoul Bochun Medical Clinic Examined Patient Table' is a statistical data that Kim Young-Boon [1882-1974] put together himself. A total of 59353 cases from 1914 to 1935 were classified according to year and month of examination, and gender. Of the cases 26497 (${\fallingdotseq}$45%) were women and the remaining 32856 (${\fallingdotseq}$55%) cases were men. The most frequent disease examined was cold, followed by diarrhea and stomachache. Of the 639 different kinds of diseases ever examined, 71 had occurred on more than 100 occasions. The percentage that these 71 diseases occupies is an overwhelming 88.75%.