• 동의생리병리학회지
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• 제16권2호
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• pp.338-342
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• 2002

In order to evaluate the effect of Ginseng Radix(GR) against endocrine disrupting chemicals(EDC), cultured mouse osteoblasts were preincubated with various concentrations of GR extract before the exposure of Bisphenol A for 12 hours. Cytotoxic effect of Bisphenol A was measured by the XTT assay. In addition, the protective effect of GR over Bisphenol A-induced cytotoxicity on osteoblasts was assessed by the DNA and protein synthesis in these cultures. The results were as follows : Osteoblastic cell viability was decreased in dose and time dependent manner after exposed to various concentrations of Bisphenol A. Midcytotoxicity value(MCV50) of Bisphenol A was determined at 6μM Bisphenol A after osteoblasts were grown for 12 hours in the media containing various concentrations of Bisphenol A. Amount of DNA synthesis was increased in dose-dependent manner after cultured osteblasts were pretreated with GR for 2hrs before exposure to Bisphenol A for 12 hours. Amount of protein synthesis was increased in dose-dependent manner after cultured osteoblasts were pretreated with GR for 2 hours before exposure of Bisphenol A for 12 hours. From these results, it is suggested that Bisphenol A was highly toxic by the decrease of the cell viability, and GR is effective in the prevention of Bisphenol A-induced cytotoxicity by the increase of DNA and protein syntheses in cultured mouse osteoblasts.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.199-199
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• 2013

The distinctive cellular and mitochondrial dysfunctions of a human epithelial lung cancer cell line (H460) from a human lung fibroblastic normal cell line (MRC5) have been studied by dielectric barrier discharge (DBD) plasma treatment. The DBD plasma device have generated large amount of H2O2 and NOx in culture media which is dependent on plasma exposure time. It is found that the cell number of lung cancer cell H460 has been reduced more than the lung normal cell MRC5 as being increased exposure and incubation time. Also these both cell lines have showed mitochondria fragmentation under 5 minutes' plasma exposure, which is a clue of apoptosis. It is noted in this study that AnnexinV staining has showed not only early apoptosis, but also late apoptosis in lung cancer cell H460. Mitochondria enzyme activity and ATP generation have been also much reduced in lung cancer cell H460. Their mitochondrial membrane potential (${\Delta}{\psi}m$) has been found to be reduced in magnitude and shifted to the induced-potential level of cccp, while MRC5 mitochondrial membrane potential has been shifted slightly to that. These distinctively selective responses of lung cancer cell H460 from lung normal cell MRC5 gives us possibility of applying plasma to cancer therapy.

• 한국콘텐츠학회논문지
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• 제16권9호
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• pp.40-50
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• 2016

본 연구에서는 해외 프로그램 수용 모델을 도입, 한류를 소비하는 이질 문화권 수용자 특성과 노출, 평가가 지속적인 시청 의향에 어떠한 효과를 미치는가를 살펴보았다. 미국의 젊은 여성 수용자 176명의 응답을 분석한 결과, 한국 인지도, 일반적인 드라마 노출이 한국 드라마 노출에 직접적인 효과를 미치는 것으로 나타났으며, 한국 드라마 평가, 지속 시청 의향에도 간접적 효과를 미치는 것으로 나타났다. 한국 드라마 노출은 드라마에 대한 평가와 지속 소비 의향에 영향을 미치는 것으로 나타났으며, 드라마 평가가 지속 시청 의향에 미치는 효과는 매우 높은 것으로 나타났다. 하지만 한국인 네트워크는 종속 변인에 유의한 효과를 미치지 않는 것으로 나타났다. 이러한 연구 결과는 이질 문화권 수용자의 문화적 자산이 한국 드라마 소비에 영향을 미치고 있음을 의미한다. 일반적인 드라마 소비 성향이 이질 드라마의 소비로 연장된다는 본 연구의 결과 역시 의미 있는 발견으로, 한류 시장 확대를 위한 정책에 시사점을 제공한다.

• 한국산업보건학회지
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• 제30권3호
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• pp.292-298
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• 2020

Objectives: The aim of this research is to establish Similar Exposure Groups (SEGs) for chemical and biological risk factors that occur in farm work involving 24 tasks among 15 crops. Methods: To categorize SEGs, work type, work environment, and similar tasks for each crop were considered. After confirming the chemical risk factors (pesticides, inorganic dust-total dust and PM₁₀, ammonia, and hydrogen sulfide) and biological factors (organic dust-total dust and PM₁₀, and endotoxins) that occur in the crops and tasks, similar crops and tasks were selected as SEGs. Results: Among chemical risk factors, pesticides was selected for the SEGs, which was categorized by open field, greenhouse, fruit, and specialty crops. For inorganic dust, open field (plowing harrowing, seedling, planting, harvest, and sorting and packing) and specialty crops (plowing harrowing, seedling, planting, and harvest) were selected as SEGs. For ammonia and hydrogen sulfide, livestock (preparation of farm, management of nursery bed, feeding, shipment and manure treatment) were selected as SEGs. For biological risk factors such as organic dust (total dust, PM₁₀) and endotoxins, open field (manure application), greenhouse (plowing harrowing, planting, manure application, and harvest), fruit (manure application), specialty crops (manure application, making furrows, mixing mushroom media, harvest, and sorting and packing), and livestock (preparation of farm, maintaining poultry litter, feeding, shipment and manure treatment) were selected as SEGs. Conclusions: To establish similar exposure groups in agriculture, it is important that the characteristics of each hazard factor are categorized by identifying risk factors occurring by tasks.

• 방송공학회논문지
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• 제21권2호
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• pp.200-209
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• 2016

본 논문에서는 촬영 시 발생하는 블러 현상을 효율적으로 제거하기 위해 IMU 센서와 노출시간이 길고, 짧은 두 영상을 이용한 비균일 디블러 알고리즘을 제안한다. 종래 센서 정보를 이용한 블러 커널 추정 기법들은 센서 정보의 한계로 인해 성능이 만족스럽지 못하다. 그 한계를 극복하기 위해 우리는 노출시간이 서로 다른 여러 영상들을 이용한 커널 개선 과정을 제안하여, 추정된 커널의 정확도를 향상시킨다. 또한 종래 비균일 디블러 기법들이 블러 커널이 커질수록 심한 화질 열화를 겪는 문제점을 해결하기 위해 본 논문은 호모그래피 기반 잔여 디콘볼루션을 제안하여 디콘볼루션 과정에서 발생하는 링형 현상과 같은 화질 열화를 최소화한다. 실험 결과를 통해 제안 알고리즘의 화질이 기존 기법에 비해 주관적/객관적으로 현저하게 우수함을 볼 수 있다.

• Fisheries and Aquatic Sciences
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• 제9권4호
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• pp.140-145
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• 2006

We measured activities of the ubiquitous tripeptide non-protein thiol (L-${\gamma}$-glutamyl-L-cysteinyl-glycine), glutathione (GSH), which is believed to playa fundamental role in detoxifying xenobiotics in biological systems, as a metabolic biomarker for benzo(${\alpha}$)pyrene and Aroclor 1254 exposure in the Pacific oyster Crassostrea gigas. Reproductive oysters were exposed to the pollutants for 50 days by the algal vectoring method in which the oysters were fed with concentrated standard algal foods grown in culture media containing Aroclor 1254 (0, 5, 50, 500 ng/g) or benzo(${\alpha}$)pyrene (0, 10, 100, 1,000 ng/g). Both pollutants induced maternal GSH activities in 10 days in a dosage-dependent manner (p<0.05), although Aroclor 1254 was stronger. The pollutant-driven GSH elevation persisted for 20 to 30 days depending on the pollutants and concentrations. Thereafter, a drastic decline in the GSH activity was observed due to metabolic failure, after which the oyster GSH remained at low levels throughout the remainder of the experiment. The pollutant exposures influenced maternal reproductive output in terms of fertilization, hatching, and morphology. These results imply that changes in activity of the GST-catalyzing molecule can be used as an oyster biomarker for Aroclor 1254 and benzo(${\alpha}$)pyrene exposure.

• Journal of Radiation Protection and Research
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• 제45권4호
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• pp.154-162
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• 2020

Background: Several studies have reported that wild mushrooms contain high amounts of radioactive cesium (137Cs). After the Fukushima Daiichi Nuclear Power Plant Accident, a significantly high concentration of 137Cs has been detected in wild mushrooms, and their consumption may be the cause of the chronic internal exposure of local consumers to radioactivity. Therefore, an accurate evaluation of the internal radioactivity resulting from mushroom ingestion is needed. Materials and Methods: The 137Cs elution rate through the cooking and digestion stages was evaluated using in vitro experiments. The edible mushroom Pleurotus djamor was taken as a sample for the experiments. The mushrooms were cultivated onto solid media containing 137Cs. We evaluated the internal dose based on the actual conditions using the elution rate data. For various cooking methods, the results were compared with those of other wild edible mushrooms. Results and Discussion: From the elution experiment through cooking, we proved that 25%-55% of the 137Cs in the mushrooms was released during soaking, boiling, or frying. The results of a simulated digestion experiment after cooking revealed that almost all the 137Cs in the ingested mushrooms eluted in the digestive juice, regardless of the cooking method. The committed effective dose was reduced by 20%-75% when considering the dissolution through the cooking process. Conclusion: We found that cooking lowers 137Cs concentration in mushrooms, therefore reducing the amount of radioactivity intake. Besides, since there were differences between mushroom types, we demonstrated that the internal exposure dose should be evaluated in detail considering the release of 137Cs during the cooking stages.

• 한국콘텐츠학회논문지
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• 제21권5호
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• pp.157-169
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• 2021

2019 디지털뉴스 리포트에 따르면, 한국은 다른 국가들에 비해 유튜브를 통한 뉴스 이용 비중이 상대적으로 높은 편이다. 유튜브를 통한 정치뉴스 이용이 증가하게 되면, 사람들은 유튜브가 추천한 특정 정치이념에 선택적으로 노출되고 확증 편향된 사고방식을 갖게 되어 정치 집단 갈등의 골이 깊어질 수 있다. 사회적 정체성 이론(Social Identity Theory)에 따르면, 특정 정치 집단에 대한 내집단 의식이 강해질수록 외집단에 대한 반감이 더 커지거나 내집단에 대한 애착이 커지면서 정치적 집단 간 갈등이 극화될 수 있다. 이 연구는 일상적으로 소비되고 있는 유튜브 정치 동영상의 선택적 노출과 태도극화 현상을 진단하였고, 사회적 정체성 이론을 근거로 정치적 내집단 의식이 선택적 노출과 태도극화 간 관계를 매개한다는 사실을 밝혔다. 이 연구의 결과는 정치성향에 따라 정치적 내집단 의식의 매개효과가 상이하게 나타날 수 있음을 의미한다.

• 한국융합학회논문지
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• 제13권4호
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• pp.373-381
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• 2022

2011년 3월 동일본 대지진으로 인한 후쿠시마 원전수 유출 사고는 방사능에 오염된 수산물 섭취를 통한 방사능 피폭에 대한 두려움을 높였다. 이에 따라 우리나라 정부는 후쿠시마 인근 8개 현의 농수산물 수입을 금지하였으나 일본과의 WTO 분쟁 등으로 관련 내용이 지속적으로 보도되었고 이는 수산물에 대한 소비자의 불안을 가중시킨 것으로 보인다. 본 연구는 3년간(2018년~2020년)의 수산물 일별 구매 자료를 수집하여 일본 방사능과 관련한 보도가 국내 소비자의 수산물 구매액에 미치는 영향을 다항시차분포모형을 사용하여 추정하였다. 분석 결과 방사능 관련 기사가 언론을 통해 소비자에게 노출된 후 5일째와 6일째 이틀간 통계적으로 유의하게 수산물 구매에 부정적 영향을 미친 것으로 나타났다. 관련 기사 노출 후 소비자의 인지가 수산물 구매에 반영되는 이월효과를 보여준다.

• Korean Journal of Radiology
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• 제21권10호
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• pp.1178-1186
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• 2020

Objective: To evaluate the incidence and risk factors of emetic complications associated with the intravenous administration of low-osmolality iodinated contrast media (ICM) in children undergoing computed tomography (CT). Materials and Methods: All children who underwent contrast-enhanced CT between April 2017 and July 2019 were included. Pediatric patients were instructed on the preparative dietary protocol at our institution. Experienced nurses in the radiology department monitored the children during the CT scans and recorded any emetic complications in their electronic medical records. These data were used to calculate the incidence of emetic complications. Various patient factors and technical factors, including fasting duration, the type and volume of ICM, and ongoing chemotherapy, were evaluated to identify risk factors for emetic complications using univariate and multivariate logistic regression analyses. Results: Among the 864 children (mean age, 8.4 ± 5.7 years) evaluated, 18 (2.1%) experienced emetic complications (6 experienced nausea only and 12 experienced nausea and vomiting). None of the children developed aspiration pneumonia. The mean fasting duration of patients with emesis was 7.9 ± 5.7 hours (range, 3-21 hours), whereas that of patients without nausea was 8.7 ± 5.7 hours (range, 0-24 hours). Fasting duration was not associated with the development of nausea and vomiting (p = 0.634). Multivariate logistic regression analysis revealed that ongoing chemotherapy (odds ratio [OR] = 4.323; 95% confidence interval [CI] = 1.430-13.064; p = 0.009), iomeprol use (OR = 7.219; 95% CI = 1.442-36.146; p = 0.016), and iohexol use (OR = 5.241; 95% CI = 1.350-20.346; p = 0.017) were independent risk factors for emetic complications. Conclusion: Only a small proportion (2.1%) of children experienced nausea or vomiting after exposure to low-osmolality ICM. Many children underwent excessive fasting; however, fasting duration was not associated with nausea and vomiting. Moreover, ongoing chemotherapy and the use of iomeprol or iohexol were identified as potential risk factors for emetic complications in children.