• Title/Summary/Keyword: measuring activities

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Inhibitory Effect of Capsaicin against Carcinogen-induced Oxidative Damage in Rats

  • Yu, Ri-Na;Park, Min-Ah;Kawada, Teruo;Kim, Byung-Sam;Han, In-Seob;Yoo, Hoon
    • Preventive Nutrition and Food Science
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    • 제7권1호
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    • pp.67-71
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    • 2002
  • Capsaicin (trans-8-methyl-N-vanillyl-6-nonenarnide), a major pungent component of hot pepper, is known to exert antioxidative properties. In this study, we investigated the protective effects of capsaicin against chemical carcinogen-induced oxidative damage in rats. Male Sprague Dawley rats weighting 230~250 g were treated with chemical carcinogens such as 2-nitropropane (2NP) or n-methyl-N'-nitro-N-nitrosoguanidine (MNNG) after (or before) the administration of capsaicin at doses of 0.5, 1,5 mg/kg. The level of lipid peroxidation in rat liver was estimated by measuring the amounts of thiobarbituric acid reactive substances. The degree of oxidative DNA damage was evacuated by measuring a DNA adduct, 8-hydroxydeoxyguanosine (8-OHdG), in urine. Antioxidative activities of capsaicin and its metabolites in vitro were determined by the measurement of DPPH (1,1-diphenyl-2-picrylhydrazyl), a radical quencher. Significant inhibition of 2-NP induced lipid peroxidation was observed in the liver of the rat when treated with capsaicin. MNNG-induced urinary excretion of 8-OHdG was decreased by capsaicin treatment. Capsaicin and its metabolites inhibited net only the formation of free radicals, but also lipid peroxidation in vitro. Our results show that capsaicin may function as a free radical scavenger against chemical carcinogen-induced oxidative cellular damage in vivo. The observed antioxidative activities of capsaicin may play an important role in the process of chemoprevention.

공격성 아동을 위한 음악치료 -타악기 연주활동 중심의 사례연구- (Therapeutic use of percussion instruments for children with aggressive behaviors - Case studies with quantitative and qualitative approaches -)

  • 한지현
    • 인간행동과 음악연구
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    • 제2권2호
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    • pp.33-56
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    • 2005
  • 본 연구의 목적은 공격성 아동을 대상으로 하여 타악기 중심의 음악활동이 아동의 공격성에 미치는 효과를 사례연구를 통해서 알아보고 그 치료적 프로그램을 제시하는데 있다. 본 연구에서는 공격성 아동 3명을 대상으로 타악기 중심의 음악활동 프로그램을 적용하여 7주에 걸쳐 총 21회 소그룹 세션을 실시하였고 각 세션은 30분으로 구성하였다. 공격성 아동의 선정은 4학년에 재학 중인 학생을 대상으로 곽금주(1992)가 다소 수정하여 만든 교사평정용 공격성 측정도구를 사용하여 공격성 점수가 높은 아동 3명을 선정하였다. 또한 이들에게 조해연(2001)과 이주식(2003)이 사용한 척도를 수정 보완한 16문항의 자기 질문식 충동성 측정 도구를 사용하여 충동성 검사도 함께 사전 실시하였다. 이를 통하여 사례아동의 공격성과 충동성 측정 도구의 사전-사후 검사 결과와 함께 음악활동 개입 후 치료 초기(1~3회기)와 후기(19~21회기)의 공격적 행동발생 변화를 데이터화하여 비교 분석 하는 양적인 연구와 타악기 연주활동이 아동에게 미친 반응을 관찰 기록하는 질적인 연구를 동시에 하였다. 연구 결과는 공격성 측정도구의 사후검사 점수가 사례아동 A는 19점에서 16점으로, 사례아동 B는 23점에서 19점으로, 사례아동 C는 21점에서 18점으로 낮아졌으며 충동성 측정도구의 사후검사 점수도 사례아동 3명 모두 낮아졌음을 보여주었다. 또한 목표행동 발생 빈도수의 변화도 음악치료 초기보다 후기로 갈수록 감소한 결과를 나타내었다. 사례아동의 질적 연구결과는 타악기 연주활동 후 자기표현을 통해 스트레스 해소라는 감정상태의 변화를 나타내었다. 이러한 양적 질적 분석의 결과들은 타악기 중심의 음악치료 프로그램이 사례아동에게 공격성 감소라는 치료적 효과를 보여준 것으로 타악기가 공격성 아동을 위해 유용한 치료적 수단으로 활용될 수 있음을 입증한 것이라 할 수 있다.

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일 대학 병원 마취${\cdot}$회복실 간호사의 간호활동 분석 (Analysis of Anesthesia and Recovery Room Nurses's Activities)

  • 강윤경;김경미;김연이;박혜옥;서광희;송숙녀;이현숙;조의영
    • 간호행정학회지
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    • 제12권1호
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    • pp.63-75
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    • 2006
  • Purpose: This study was aimed to specify roles of nurses from the anesthesia and recovery room by analyzing nursing activities as well as anesthesia nursing during surgery. Method: The objects were 12 RNs working in the recovery room of a university hospital located in Incheon. Self-report was performed by measuring stop-watch for five days from May 17th to May 21st in 2004. Research method was designed to record the time and frequency of the nursing activity from anesthesia and recovery room based on nurses' statement and other references for five days. The data were analyzed with descriptive statistics, ANOVA, and t-test via SPSS Win 10.0 program. Result: Nursing activities in anesthesia recovery room were classified into two different characteristics such as direct and indirect nursing activity. The activities consisted of 11 direct nursing areas and 39 nursing activities in anesthesia preparation room. The indirect nursing was classified into 8 nursing areas and 32 nursing activities. The direct nursing was classified into 12 nursing areas and 55 nursing activity. Also, the indirect nursing was classified into 7 nursing areas and 21 nursing activities in recovery room. In terms of prevalence of nursing activities in the anesthesia preparation room, observation and cooperation of anesthesia was the most prevalent activity, drug and eqipment management the second prevalent, and drug administration the third. On the other hand, in the recovery room, the most prevalent activity was vital sign checking and observation, the second most prevalent activity informative activity, and the third body temperature control. Nursing activity time was recorded according to the nursing characteristics. In the anesthesia preparation room, the direct nursing spent for 8092.20 minutes was larger than the indirect nursing spent for 7198.50 minutes. Also, in the recovery room, the direct nursing spent for 2361.16 minutes was larger than the indirect nursing spent for 1134.13 minutes. 4. Nursing activity time was compared to duty shifts. In the anesthesia preparation room, the direct nursing was more prevalent on day shift and the indirect nursing was prevalent on evening shift. However, in the recovery room, both direct and indirect nursing activities were prevalent on day shift. Conclusion: The role of anesthesia and recovery room nurses was analysed according to the time, frequency, and its characteristics.

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금융회사의 고객정보보호에 대한 내부직원의 태도 연구 (The Behavioral Attitude of Financial Firms' Employees on the Customer Information Security in Korea)

  • 정우진;신유형;이상용
    • Asia pacific journal of information systems
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    • 제22권1호
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    • pp.53-77
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    • 2012
  • Financial firms, especially large scaled firms such as KB bank, NH bank, Samsung Card, Hana SK Card, Hyundai Capital, Shinhan Card, etc. should be securely dealing with the personal financial information. Indeed, people have tended to believe that those big financial companies are relatively safer in terms of information security than typical small and medium sized firms in other industries. However, the recent incidents of personal information privacy invasion showed that this may not be true. Financial firms have increased the investment of information protection and security, and they are trying to prevent the information privacy invasion accidents by doing all the necessary efforts. This paper studies how effectively a financial firm will be able to avoid personal financial information privacy invasion that may be deliberately caused by internal staffs. Although there are several literatures relating to information security, to our knowledge, this is the first study to focus on the behavior of internal staffs. The big financial firms are doing variety of information security activities to protect personal information. This study is to confirm what types of such activities actually work well. The primary research model of this paper is based on Theory of Planned Behavior (TPB) that describes the rational choice of human behavior. Also, a variety of activities to protect the personal information of financial firms, especially credit card companies with the most customer information, were modeled by the four-step process Security Action Cycle (SAC) that Straub and Welke (1998) claimed. Through this proposed conceptual research model, we study whether information security activities of each step could suppress personal information abuse. Also, by measuring the morality of internal staffs, we checked whether the act of information privacy invasion caused by internal staff is in fact a serious criminal behavior or just a kind of unethical behavior. In addition, we also checked whether there was the cognition difference of the moral level between internal staffs and the customers. Research subjects were customer call center operators in one of the big credit card company. We have used multiple regression analysis. Our results showed that the punishment of the remedy activities, among the firm's information security activities, had the most obvious effects of preventing the information abuse (or privacy invasion) by internal staff. Somewhat effective tools were the prevention activities that limited the physical accessibility of non-authorities to the system of customers' personal information database. Some examples of the prevention activities are to make the procedure of access rights complex and to enhance security instrument. We also found that 'the unnecessary information searches out of work' as the behavior of information abuse occurred frequently by internal staffs. They perceived these behaviors somewhat minor criminal or just unethical action rather than a serious criminal behavior. Also, there existed the big cognition difference of the moral level between internal staffs and the public (customers). Based on the findings of our research, we should expect that this paper help practically to prevent privacy invasion and to protect personal information properly by raising the effectiveness of information security activities of finance firms. Also, we expect that our suggestions can be utilized to effectively improve personnel management and to cope with internal security threats in the overall information security management system.

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4차 산업혁명 시대의 기업사회공헌 활동의 진화 (Evolution of corporate social contribution activities in the era of the Fourth industrial revolution)

  • 김민석;조영복
    • 한국산학기술학회논문지
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    • 제20권1호
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    • pp.85-95
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    • 2019
  • 최근 정부와 기업, 학계에서 4차 산업혁명에 대한 학습과 연구가 활발히 진행되고 있다. 로봇과 인공지능, 블록체인과 사물인터넷 등 4차 산업혁명의 주요 아젠다를 활용한 기업 비즈니스 모델이 생겨나고, 지금까지의 기업환경, 교육환경, 생활환경뿐만 아니라 국제개발협력에서도 다양한 변화가 생기기 시작하였다. 본 연구에서는 4차 산업혁명의 영향을 가장 가까이 직면하고 있는 기업에서 진행하고 있는 사회공헌 활동의 변화를 살펴보았다. 즉 기업사회공헌의 정의와 활동내용을 살펴보고 4차 산업혁명이라고 불리는 현시대에서 각 기업이 갖고 있는 본연의 비즈니스를 통해 사회에 어떻게 기여할 수 있는지 사파리콤의 '엠페사', LG전자의 'AT Educom', LG유플러스의 '사물인터넷 활용 사회공헌' 그리고 KT의 '감염병 확산방지 플랫폼', 그리고 IoT를 활용한 Intel의 사례를 통해 확인해보았다. 그리고 기술개발에 따라 앞으로의 기업사회공헌 활동이 어떻게 변화할 것인지, 더욱 의미 있는 임팩트를 만드는 기업사회공헌 활동이 되기 위해 필요한 것들을 제시하였다. 가장 먼저는 기업사회공헌 활동의 성과측정이 용이해질 것과, 플랫폼을 활용한 사회공헌 활동이 증가하고, ICT 업계에서 기술을 통한 사회기여 활동이 활발하게 진행되며, 마지막으로는 기업간, 섹터간 공동으로 진행하는 사회공헌 활동이 늘어나게 되어, 기업이 영리만을 추구하는 집단이라는 인식에서 벗어나 앞으로는 사회를 위해 존재하는 기업시민으로서의 역할을 할 수 있음을 설명하였다.

가미행체탕 합 육미지황탕이 Oxidant 및 Hg에 의한 가토 간세포손상에 미치는 영향 (The Effect of Kamihaengche-tang Plus Yukmijihwang-tangon Oxidant and Hg-induced Rabbit's Liver Cell Injury)

  • 이수행;김원길;김우환
    • 대한한의학회지
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    • 제23권3호
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    • pp.174-187
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    • 2002
  • Objectives : This study was carried out to determine whether Kamihaengche-tang plus Yulanijihwang-tang (KCYH) exerts a protective effect against oxidant-induced liver cell injury. Methods : Cell injury was estimated by measuring lactate dehydrogenase (LDH) and alanine aminotransferase (ALT) release, and lipid peroxidation was estimated by measuring malondialdehyde, a product of lipid peroxidation in rabbit liver slices. Results : Oxidants (tBHP and $H_2O_2$) increased dose-dependently LDH release which was significantly prevented by 1% KCYH. The protective effect of KCYH against oxidant-induced cell injury was dose-dependent in the range of 0.05-1 % concentrations. Similarly, KCYH inhibited oxidant-induced lipid peroxidation in a dose-dependent manner. When liver tissues were exposed to Hg (0.5 mM), ALT activity in the medium and lipid peroxidation in tissues were markedly increased. These changes were prevented by 1% KCYH, KCYH restored toxicant-induced inhibition of cellular GSH content. KCYH increased the activities of catalase and glutathion peroxidase in oxidant-treated tissues. Conclusions : These results indicate that KCYH exerts a protective effect against oxidant-induced liver cell injury, and this effect is attributed to prevention of lipid peroxidation. These effects may be due to an increase in concentration of endogenous antioxidants.

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가상현실에서의 뇌파측정을 위한 디자인 고찰 및 제안 (The New Design of Brain Measurement System for Immersive Virtual Reality)

  • 김경모;전준현
    • 한국HCI학회논문지
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    • 제12권4호
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    • pp.75-80
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    • 2017
  • 최근 인지과학의 활발한 연구와 기술의 발달로 인해 사회과학분야에서 정신생리학적 연구를 통한 뇌의 다양한 측정과 정교한 분석 기법이 개발 되었다. 그러나 뇌파를 이용한 뉴미디어활용에 관한 연구는 장비들을 장착하는 과정에서의 한계점으로 인해 진행되지 못하였다. 이러한 문제를 극복하고자, 가상현실장비를 착용한 상태에서도 전 영역의 뇌파측정이 가능한 캡을 디자인하고 활용방법을 제안한다.

Measuring AGN Core-shift Effect by Extended KVN with Global Baselines

  • Jung, Taehyun;Dodson, Richard;Han, Seog-Tae;Byun, Do-Young;Sohn, Bong Won;Rioja, Maria J.;Honma, Mareki;Stevens, Jamie;de Vincente, Pablo
    • 천문학회보
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    • 제40권2호
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    • pp.43.3-44
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    • 2015
  • Very Long Baseline Interferometry (VLBI) at millimeter wavelengths results in the highest angular resolutions achieved in astronomy and has a unique access to emission regions that are inaccessible with any other approach or at longer wavelengths. The simultaneous multi-frequency VLBI system in the Korean VLBI Network (KVN) is considered one of the most effective systems for compensating the atmospheric phase fluctuations, which is particularly bothersome at mm-VLBI. We have been demonstrating its performance and uniqueness at mm-VLBI observations. As a results, international VLBI partners from Japan, China, Australia and EU have expressed their interest on the KVN style simultaneous multi-frequency system. In this talk, we will report the activities for extending the simultaneous multi-frequency system to global VLBI network and introduce its science driver, measuring AGN core-shift effects.

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TACT 공정관리 시스템 개발 및 적용 사례 (Development and Application of TACT Management System)

  • 서상욱;김재호;김선국;김창덕;이현수
    • 한국건설관리학회논문집
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    • 제4권4호
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    • pp.145-154
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    • 2003
  • 건설산업의 환경변화와 정보기술의 발달에 따라 건설사업 효율성 향상의 필요성이 커지고 있다. 그러나 건설사업의 효율성 제고를 위한 관리시스템의 필수요건이 되는 성과측정 도구는 여전히 부족한 실정이다. 한편, 공정관리의 경우, 공사수행 결과로 나타나는 시간, 비용, 진도 율 등의 실적위주로 관리되고 있으며, 진행단계에서의 전체 작업간의 연속적 흐름에 대한 관리는 제대로 이루어지지 못하고 있다. 따라서 본 연구에서는 건축공사의 계획단계에서부터 진행단계, 최종 평가에 이르는 프로세스의 시스템화를 시도하였고, 특히 택트 공정관리의 시스템화를 통하여 공사수행 과정 중의 마감공사 수행 정도를 측정할 수 있는 지표를 개발하고 이를 활용하는 방안을 제시하였다.

급성기 뇌졸중 환자의 기능상태 측정을 위한 ICF 핵심지표 (ICF Core Sets for Measuring Functional Status of Acute Stroke Patients)

  • 박미진;강지연
    • 근관절건강학회지
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    • 제19권2호
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    • pp.107-119
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    • 2012
  • Purpose: This study was conducted to extract international classification of functioning, disability, and health (ICF) core sets for measuring functional status in acute stroke patients, and to evaluate clinical applicability of the core sets. Methods: A set of 22 ICF items on functional status in acute stroke patients were extracted from the Korean general ICF core sets and ICF core sets for stroke patients. The extracted ICF functional items were assessed at the time of admission and discharge among 100 stroke patients who were admitted in a university hospital. Results: Comparing to functional status at admission of acute stroke patients, the overall functional status at discharge was improved. However, functions on defecation, skin protection, and relationship with immediate family at the time of discharge were not significantly changed. Conclusion: The set of ICF functional items identified in this study may be reliable and valid to assess acute stoke patients' body functions, activities and participation and environmental factors in the holistic and comprehensive nursing context. Nursing interventions on bowel elimination and skin protection for acute stroke patients need to be developed.