• 제목/요약/키워드: measurement of permeability

검색결과 256건 처리시간 0.03초

The Characterization of the Increase of Membrane Conductance after Depolarization in Single Rat Adrenal Chromaffin Cells

  • Lim, Won-Il;Kim, Sang-Jeong;Kim, Jun
    • The Korean Journal of Physiology and Pharmacology
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    • 제2권1호
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    • pp.95-100
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    • 1998
  • The conductance change evoked by step depolarization was studied in primarily cultured rat adrenal chromaffin cells using patch-clamp and capacitance measurement techniques. When we applied a depolarizing pulse to a chromaffin cell, the inward calcium current was followed by an outward current and depolarization-induced exocytosis was accompanied by an increase in conductance trace. The slow inward tail current which has the same time course as the conductance change was observed in current recording. The activation of slow tail current was calcium-dependent. Reversal potentials agreed with Nernst equation assuming relative permeability of $Cs^+\;to\;K^+$ is 0.095. The outward current and tail current were blocked by apamin (200 nM) and d-tubocurarine (2 mM). The conductance change was blocked by apamin and did not affect membrane capacitance recording. We confirmed that conductance change after depolarization comes from the activation of the SK channel and can be blocked by application of the SK channel blockers. Consequently, it is necessary to consider blocking of the SK channel during membrane capacitance recording.

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양모 방축가공에 따른 물리적 성질 변화 (A Study on Physical Properties of Wool with Shrink-resist treatment and Felting)

  • 정아현;김종준
    • 패션비즈니스
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    • 제19권2호
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    • pp.23-35
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    • 2015
  • In this study, the effect of shrink-resist treatment agent on the wool finishing, specifically anti-felting of wool product was studied. We aimed at providing preliminary data leading to the diversification of high-value added fashionable wool product. Two type of wool fabrics, dense and sheer, were employed. The fabric specimens were treated with solutions of shrink-resist treatment agent with wet pick-up rate 110%, 130%, and 150%, respectively, by using a padding mangle. The solution treated fabric specimens were then dried at room temperature first, at $90^{\circ}C$ for 15 minutes in a drying oven, and finally cured at $130^{\circ}C$ for 3 minutes. Cured wool fabric specimens were then subjected to a felting process. The physical and mechanical properties, including shrinkage rate along warp/filling direction, thickness at specified measurement pressure, drape stiffness, and air-permeability, were analyzed. After felting process, the shrinkage rates of wool fabric specimens, treated with shrink-resist treatment agent, were lower than those of control wool fabric specimens. The stiffness values of wool fabric specimens measured by using Flexometer were increased.

그라우트 재료에 따른 지중 열교환기의 열전도도에 관한 실험적 연구 (Thermal Conductivity Measurement of Grouting Materials for Geothermal Heat Exchanger)

  • 임효재;공형진;송윤석;박성구
    • 설비공학논문집
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    • 제17권4호
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    • pp.364-369
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    • 2005
  • An experimental study was conducted on the thermal conductivity of various grouting materials for geothermal heat exchanger which is used as a heat sink or source in the heat pump system. The grouting of the vertical heat exchanger is important for environmental and heat transfer reasons and is generally accomplished by the placement of a low permeability material into the annular space between the borehole wall and the pipes suspended in the borehole. In this study, a lab scale test apparatus was made and measured the thermal conductivity of four grouting materials. As a result, the temperature rising tendency was similar among them, but the increasing rate was different. Thus the thermal conductivity showed a maximum difference of $27\%$ among grouting materials.

Investigation of Demixing Phenomena of a Polymer Solution During the Phase Inversion Process

  • Han, Myeong-Jin;D. Bhattacharyya
    • 한국막학회:학술대회논문집
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    • 한국막학회 1995년도 춘계 총회 및 학술발표회
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    • pp.11-15
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    • 1995
  • Polysulfone (PS) membranes were prepared by the phase inversion process using water or isopropanol as nonsolvent. The Flory-Huggins theory for a ternary system nonsolvent/solvent/polymer is applied to describe the thermodynamic equilibria of the components. The calculated ternary phase equilibria show that demixing of a PS binary solution with n-methylpyrrolidone (NMP) will be fast in a water coagulation bath and will be delayed in an isopropanol bath. The prepared membranes were characterized by SEM, gas adsorption-desorption measurement, and permeability test. The membrane, which is precipitated by fast demixing in a water bath, has nodular structures in the skin region and includes finger-like cavities in the sublayer. The membrane coagulated by isopropanol has a very dense and thick skin structure, which is formed by delayed demixing. The membrane coagulated by isopropanol showed considerably lower pore volume and surface area compared to that observed with water coagulation method. With dimethylformamide (DMF) as solvent and 2-3 wt% of water, the solution can show the liquid-liquid phase separation due to agglomation of the polymer-lean phase from the homogeneous solution. The membranes, which were coagulated near an equilibrium state, show the large (micron size) round pores in the whole membranes. The pores do not contribute the permeation characteristics.

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Non-Bianisotropy 특성을 갖는 IDC로 구성된 메타 물질 단위 셀 설계 (Design of a Metamaterial Unit Cell Using an Interdigital Capacitor with Non-Bianisotropic Property)

  • 권결;하재근;이영기;최재훈
    • 한국전자파학회논문지
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    • 제23권3호
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    • pp.402-405
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    • 2012
  • 본 논문에서는 non-bianisotropy 특성을 갖는 IDC(Interdigital Capacitor)를 이용한 메타 물질(metamaterial) 단위셀 구조를 제안하였다. IDC 단위 셀에 유도되는 자기 공진으로 인하여 SRR(Spilt Ring Resonator)와 같이 특이한 유효 매질 파라미터 값들이 나타내게 된다. 제안된 단위 셀은 기존의 SRR 단위 셀 구조에 비하여 전기적으로 더 작게 설계할 수 있다. 도파관 측정법을 이용하여 얻은 응답 특성을 통해 추출된 셀의 유효 파라미터 값은 시뮬레이션을 통해 얻어진 결과와 유사한 특성을 보였다.

온도센서 배열 모니터링에 의한 매질의 투수성 및 절리 연결성 연구 (A Study on the medium seepage and the fracture connectivity by using temperature monitoring with thremal line sensors)

  • 김중열;김태희;김유성
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2006년도 춘계 학술발표회 논문집
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    • pp.1110-1119
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    • 2006
  • If water flows through a narrow passage into a medium that keeps the equilibrium of temperature, it causes small temperature difference and makes a temperature anomaly. The seepage or leakage often observed at old dams is a representative example of bringing about a temperature anomaly. Therefore, temperature measurements have been regarded as one of excellent methods that can detect the situation of seepage or leakage. However, because existing temperature measurement methods are based on a single sensor, the application of the method to the whole structure is nearly not possible in technical and economical phases. This paper introduces a temperature monitoring system using a thermal sensor cable that is comprised of addressable thermal sensors connected in parallel at many positions within a single cable. Through various laboratory and field experiments, it has been proved that the temperature monitoring technique can give an useful information about permeability of a medium or connectivity of fractures which have been regarded as difficult problems.

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Preparation and characterization of TiO2 membrane on porous 316 L stainless steel substrate with high mechanical strength

  • Mohamadi, Fatemeh;Parvin, Nader
    • Membrane and Water Treatment
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    • 제6권3호
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    • pp.251-262
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    • 2015
  • In this work the preparation and characterization of a membrane containing a uniform mesoporous Titanium oxide top layer on a porous stainless steel substrate has been studied. The 316 L stainless steel substrate was prepared by powder metallurgy technique and modified by soaking-rolling and fast drying method. The mesoporous titania membrane was fabricated via the sol-gel method. Morphological studies were performed on both supported and unsupported membranes using scanning electron microscope (SEM) and field emission scanning microscope (FESEM). The membranes were also characterized using X-ray diffraction (XRD) and $N_2$-adsorption / desorption measurement (BET analyses). It was revealed that a defect-free anatase membrane with a thickness of $1.6{\mu}m$ and 4.3 nm average pore size can be produced. In order to evaluate the performance of the supported membrane, single-gas permeation experiments were carried out at room temperature with nitrogen gas. The permeability coefficient of the fabricated membrane was $4{\times}10^{-8}\;lit\;s^{-1}\;Pa^{-1}\;cm^{-1}$.

감온 페라이트를 이용한 비접촉 온도측정시스템의 감도특성 (Sensitivity of non-contact Temperature Measurement Using Temperature Sensitive Ferrite)

  • 신광호;김영학
    • 한국자기학회지
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    • 제14권1호
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    • pp.1-6
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    • 2004
  • 비접촉 온도측정 시스템을 구현하기 위하여 감온페라이트를 이용하여 제작한 인던턴스소자와 캐피시터를 접속하여 LC공진형 센서를 구성하고, 비접촉 온도계측성능에 대하여 조사하였고, 송수신기 사이의 거리에 대한 측정감도에 대하여 검토하였다. 감온 페라이트가 가지는 투자율의 온도의존성에 의해서 제작한 센서의 인덕턴스와 공진주파수가 변화함을 알 수 있었고, 공진주파수의 변화를 비접촉으로 검출함으로써 비접촉으로 온도를 검출할 수 있음을 알 수 있었다. 또한 비접촉 측정 감도는 송 $.$수신기 사이 거리의 6승에 비례하는 감소하는 것을 알 수 있었다.

실리콘계 고분자막의 제조와 투과증발법에 의한 유기염소계 화합물 제거 (Preparation of Silicone Polymeric Membrane and Removal of Chlorinated Organic Compounds by Pervaporation)

  • 백귀찬;이용택;김용옥
    • 멤브레인
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    • 제9권2호
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    • pp.114-125
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    • 1999
  • Poly(1-trimethylsilyl-1-propyne)(PTMSP), poly(dimethylsiloxane)(PDMS) 막 및 PTMSP-g-PDMS막 등의 균질 치밀막을 제조하여 chloroform, trichloroethylene(TCE), perchloroethylene (PCE) 등의 유기염소계 화합물에 대한 투과증발 분리성능을 평가한 결과 PCE 대해 가장 높은 선택성을 나타내었다. PTMSP 막들의 경우는 시간이 지나면서 투과특성이 현저히 감소하였으나 PTMSP-g-PDMS 막은 지속적인 투과특성을 나타내어 시간이 경과되어도 물리적 노화현상은 거의 없었다. 또한 접촉각 측정 결과 본 연구에 사용된 고분자막들은 모두 분리대상 용질에 대해 친화성을 보였으며 균질 치밀 막들에 대한 상대적 팽윤도가 클수록 신택도가 증가하였다.

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뇌 저산소증 영상 (Brain Hypoxia Imaging)

  • 송호천
    • Nuclear Medicine and Molecular Imaging
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    • 제41권2호
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    • pp.91-96
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    • 2007
  • The measurement of pathologically low levels of tissue $pO_2$ is an important diagnostic goal for determining the prognosis of many clinically important diseases including cardiovascular insufficiency, stroke and cancer. The target tissues nowaday have mostly been tumors or the myocardium, with less attention centered on the brain. Radiolabelled nitroimidazole or derivatives may be useful in identifying the hypoxic cells in cerebrovascular disease or traumatic brain injury, and hypoxic-ischemic encephalopathy. In acute stroke, the target of therapy is the severely hypoxic but salvageable tissue. $^{18}F-MISO$ PET and $^{99}mTc-EC-metronidazole$ SPECT in patients with acute ischemic stroke identified hypoxic tissues and ischemic penumbra, and predicted its outcome. A study using $^{123}I-IAZA$ in patient with closed head injury detected the hypoxic tissues after head injury. Up till now these radiopharmaceuticals have drawbacks due to its relatively low concentration with hypoxic tissues associated with/without low blood-brain barrier permeability and the necessity to wait a long time to achieve acceptable target to background ratios for imaging in acute ischemic stroke. It is needed to develop new hypoxic marker exhibiting more rapid localization in the hypoxic region in the brain. And then, the hypoxic brain imaging with imidazoles or non-imidazoles may be very useful in detecting the hypoxic tissues, determining therapeutic strategies and developing therapeutic drugs in several neurological disease, especially, in acute ischemic stroke.