• The Journal of Internal Korean Medicine
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• v.31 no.2
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• pp.346-355
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• 2010

Objectives : This study was performed in order to investigate the anti-fibrogenic effect of Acer tegmentosum Maxim. on r at hepatic stellate cell line T6. Materials and Methods : Hepatic stellate Cells (T6) were treated with various concentrations of distilled water Acer teg mentosum Maxim. extract for 24, 48, 72 hours. After the treatment, cell viability, proliferation, procollagen levels, mRNA of AS MA, MMP-2, collagen type 1a2 and IL-6 production were measured using MTT assay, BrdU assay, RT-PCR, procollagen typ e 1 C-peptide EIA kit and murine IL-6 ELISA development kit. Results : Cell viability of HSC-T6 decreased significantly in both 24 hours and 48 hours groups in a dose-dependant man ner. Proliferation of HSC also decreased in the same way. In the RT-PCR, mRNA expression of collagen type 1a2 and ASMA decreased in the groups which were treated with Acer tegmentosum Maxim. for 24 hours. The production of procollagen tended to decrease in a dose-dependant manner in the 24 hours treated group. IL-6 production increased under Acer tegmentosum trea tment in a dose-dependant manner in both 24 and 48 hours groups. Conclusion : These results show the possibility that Acer tegmentosum Maxim. can be an effective remedy for liver fibrosi s and liver cirrhosis.

• The Journal of the Korea Contents Association
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• v.13 no.7
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• pp.80-90
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• 2013

Despite the growing popularity of gay consumers as a fetching niche market, there has been little academic attention paid to the homosexual themes in print media, especially compared to research on gender, race, and sex imagery in ads. The present study aims to fill this void by examining advertisements with three different target audiences(homosexual, metrosexual, retrosexual consumer) through a comparative analysis of contemporary magazine advertisements. In this present study, we analyzed ads in three leading men's magazines (Out, GQ, and Maxim). Product (product category, price, and luxury brand) and human model (basic descriptions, sexuality, status, and masculinity) characteristics in ads were analyzed as the variables signifying the degrees of gay themes in ads across three magazines. The results showed that more expensive luxury brands were placed in GQ and Out than Maxim, and more male models were under-sexualized in Maxim than GQ and Out.

• Biomedical Science Letters
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• v.29 no.3
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• pp.152-158
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• 2023

The aim of this study is to investigate the analgesic effects of Syneilesis aconitifolia Maxim. extract (SAM). We evaluated analgesic effects of SAM on animal pain model. Male SD rats were administered intra-orally with SAM according to prescribed dosage. During 7 days. After 7 days later, serum TNF-α, IL-1β, and IL-6 levels were measured by ELISA. In our experiment, administration of SAM decreased IL-1β, IL-6, TNF-α and PGE2 level in serum. Furthermore, it was confirmed that allodynia was relieved in evaluation of pain behavior. It was confirmed that administration of SAM reduces nociceptive pain by reducing nociceptive stimuli by acting as an anti-inflammatory drug.

• Nuclear Engineering and Technology
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• v.56 no.7
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• pp.2775-2780
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• 2024

Special methods for cleaning surfaces of stainless steel with a coating simulating radioactive contamination have been developed and studied. The removal of simulated surface contamination was performed using lasers in the micron spectral range with pulse durations of 8 ns and 270 fs. Optimal cleaning modes were determined for gas and liquid environments, achieving surface cleaning coefficient of over 90% in a single pass. A correlation between the degree of cleaning in liquids and the viscosity of the environment was discovered.

• Culinary science and hospitality research
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• v.22 no.8
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• pp.27-38
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• 2016

This study examined the nutrient components and physicochemical properties of Acer termentosum Maxim. leaf as a natural health food source. To accomplish this purpose, the general and antioxidative contents of Acer termentosum Maxim leaf were measured. Total contents of carbohydrates, crude protein, crude lipid, and ash were 53.6%, 24.3%, 3.5%, and 3.5%, respectively. Caloric content of Acer termentosum Maxim was 246.5 kcal, while total dietary fiber was 46.7%. Regarding mineral contents, K was the most abundant mineral, followed by Ca, Mg, and P. Therefore, Acer termentosum Maxim is an alkali material. Total phenol contents of the 70% ethanolic extracts of Acer termentosum Maxim was $116.35{\pm}1.4mg\;GAE/g$. Total flavonoid contents of the 70% ethanolic extracts were $20.3{\pm}1.23mg\;RE/g$. The antioxidative activities of Acer termentosum Maxim. were significantly increased in a dose dependent manner on DPPH(1,1-Diphenyl-2-picrylhydrazyl) radical scavenging, ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt) radical scavenging, FRAP (ferric reducing antioxidant power) activity, reducing power. It is expected that follow up study of Acer termentosum Maxim through developing processed food and evaluation of their functional properties would provide useful information as a source of functional foods.

• Korean Journal of Environment and Ecology
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• v.30 no.4
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• pp.658-675
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• 2016

The environmental characteristics of the habitats, the population structures, ecological niche, life traits and the population demography are used as an essential informations to the effective conservation plans about the target species. We first confirmed a total of 37 populations through 12 years of investigation on the extents, and investigated the environmental factors of habitats and the population structures of the 25 cohorts in 12 regions among them. And, we investigated the population dynamics targeting at 8 cohorts in the population of Daegwanryeong-myeon, Pyeongchang-gun, Gangwon-do. Along with this, we conducted 4 years of cultivation experiments and how pollinators affect the success of reproduction. The results shows that the Paeonia obovata Maxim. was found in a relatively wide range of habitats. For the population structures of the 25 cohorts, there were considerable differences among cohorts, including a case which showed relative stable structure and an extreme case in which only adults were found. The factor that affected the population dynamics during the investigation was thought as a forest gap created in the tree layer. In the cultivation experiment, seedlings grew well in a less soil organic matter. The seed setting rate and the number of seeds generated by visiting pollinators were higher trends. In conclusion, to understand the distribution of the Paeonia obovata Maxim., there needs to be investigated on the other factors that are involved in dispersal factors other than environmental factors, and thus we suggest the necessity of the research on the dispersal vectors. The current Paeonia obovata Maxim. population was thought as a process of expansion after the rapid reduction of the extents in the past. For the effective conservation of the Paeonia obovata Maxim., an endangered plant, we recommend to understand the species through the spatio-temporal expansion, and maintain the health of the ecosystem based on it.

• Journal of radiological science and technology
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• v.46 no.1
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• pp.23-28
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• 2023

The purpose of this study is to see the radiation protection effect of the oral injected Dendranthema zawadskii var. latilobum (Maxim.) Kitam. extracts on the small intestine and uterus of female SD Rat as a natural radiation protection agent. The experimental group was divided into four groups: Normal Control group (NC group), Injected Dendranthema zawadskii var. latilobum (Maxim.) Kitam. extracts group (DZ group), irradiated group after injecting Dendranthema zawadskii var. latilobum (Maxim.) Kitam. extracts (DZ+IR group). The whole body of SD Rat was irradiated with gamma-ray 10Gy, and the administration of oral Dendranthema zawadskii var. latilobum (Maxim.) Kitam. Extract was 2 cc (71.56 mg/day/kg) once a day for 2 weeks. For this study, chages in blood cell levels, SOD assay, small intestine and uterus were observed. In the 21st white blood cell level, the DZ+IR group recovered to a normal level, and the IR group didn't. The IR group villus length was lower than other groups on Day 1. IR group was partially recovered, and DZ+IR group was recovered like the NC group on Day 21. In the case of the first-day endometrium, the IR group was thin and the boundary was cloudy, and the DZ+IR group was thicker and the boundary was clearer than the IR group. Day 21 IR group still did not recover, and DZ+IR group recovered like NC group. This is believed to have radiation protection effects in the blood cells and small intestine and uterus of the irradiated female SD Rat, and is expected to be useful for the study of natural radiation protection materials.

• Journal of Practical Agriculture & Fisheries Research
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• v.21 no.2
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• pp.5-13
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• 2019

Orostachys species grow from anywhere in Korea. This variety, which lives in the harsh areas of the beach and mountains, is known to have as much change as it was isolated. It has been used as a medicine for a long time, and now the flower is beautiful and has been developed for horticulture. As a result of morphological characteristics and component analysis of three Orostachys species, the following results were obtained. 1. Orostachys species showed two types of leaves according to the growing environment. O. japonica (Maxim.) A. Berger and O. minuta (Kom.) A. Berger were lanceolate, and O. chongsunensis Y. N. Lee was obovate. 2. The leaves were all green. However, some of the O. japonica (Maxim.) A. Berger had white powder. Some of the O. minuta (Kom.) A. Berger was green with red spots on the back. O. chongsunensis Y. N. Lee showed strong gray before flowering but weak green when flowering. 3. The thorns of the leaves were O. japonica (Maxim.) A. Berger and O. minuta (Kom.), but O. chongsunensis Y. N. Lee was not. 4. Whether it was a leaf dot or not, there were dots in O. japonica (Maxim.) A. Berger and there were dots on the O. minuta (Kom.) and the O. chongsunensis Y. N. Lee. 5. The flowers were all white, and the stamens were red in O. japonica (Maxim.) A. Berger and O. minuta (Kom.) A. Berger and white in O. chongsunensis Y. N. Lee. 6. It was confirmed that the ingredients in Orostachys species contained kaempferol, quercetin, flavonoid etc., which have high antioxidant activity.

• Korean Journal of Plant Resources
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• v.37 no.4
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• pp.307-313
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• 2024

In this study, the anti-obesity effect of Geranium wilfordii Maxim. extract was studied using 3T3-L1 cells. Geranium wilfordii Maxim. was extracted with water (NG-GT-T1L), 10% ethanol (NG-GT-T2L), 30% ethanol (NG-GT-T3L), 50% ethanol (NG-GT-T4L), 70% ethanol (NG-GT-T5L), and the effects on cell viability, lipid accumulation, triglyceride content, and protein expression in 3T3-L1 cells were confirmed. It was confirmed that NG-GT-T3L extract was superior to other extract conditions in reducing lipid accumulation and triglyceride content in the concentration range that did not show cytotoxicity. In addition, it was confirmed to suppress adipogenesis and lipogenesis by reducing the expression of peroxisome proliferator-activated receptor-gamma (PPARγ) and CCAAT/enhancer binding protein-α(C/EBPα) proteins that regulate adipogenesis, decreasing the expression of fatty acid synthetase (FAS) and stearoyl CoA desaturase-1 (SCD-1) proteins that regulate lipogenesis, and increasing the expression of AMP-activated protein kinase (AMPK) protein. From these research results, Geranium wilfordii Maxim. NG-GT-T3L extract is believed to have anti-obesity reduction effects through suppressing lipid accumulation and triglyceride accumulation and regulating adipogenesis and lipogenesis-related proteins.

• Korean Journal of Pharmacognosy
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• v.47 no.4
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• pp.327-332
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• 2016

In this study, antioxidant and anti-inflammatory activities of the extract of different organs such as seed, fruit and root from Trichosanthes kirilowii Maxim. (TKM) were investigated in vitro. Among organs of TKM, the methanol extract of seed showed weak 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities with $10.4{\pm}0.1%$ and $25.5{\pm}1.1%$ at $50{\mu}g/mL$ and $100{\mu}g/mL$, respectively, and strong 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulphonicacid) (ABTS) radical scavenging activities with $72.4{\pm}6.3%$ and $96.4{\pm}2.3%$ at $50{\mu}g/mL$ and $100{\mu}g/mL$, respectively. Anti-inflammatory effects of the extracts were investigated by measuring nitric oxide (NO) production, mRNA expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in LPS-induced Raw 264.7 macrophage cells. The methanol extracts of seed and fruit at $50{\mu}g/mL$ potently suppressed LPS-stimulated production of NO and reduced the expression of iNOS mRNA. The methanol extracts of seed and fruit also reduced the expression of COX-2 mRNA remarkably. Therefore, seed and fruit of TKM may be utilized for a wide range of health benefits associated with antioxidant and anti-inflammatory activities.