• Title/Summary/Keyword: materials for activity

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In Vivo Disease Control Efficacy of Isoquinoline Alkaloids Isolated from Corydalis ternata against Wheat Leaf Rust and Pepper Anthracnose

  • Han, Jae Woo;Shim, Sang Hee;Jang, Kyoung Soo;Choi, Yong Ho;Kim, Hun;Choi, Gyung Ja
    • Journal of Microbiology and Biotechnology
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    • v.28 no.2
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    • pp.262-266
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    • 2018
  • Phytochemicals have been considered as alternatives for synthetic fungicides because of their biodegradability and low toxicity. In this study, we found that the methanolic extract of Corydalis ternata suppressed the development of plant diseases caused by Puccinia triticina and Colletotrichum coccodes. As the antifungal substance, three isoquinoline alkaloids (dehydrocorydaline, stylopine, and corydaline) were isolated from C. ternata. These active compounds also exhibited in vivo antifungal activity against P. triticina and C. coccodes. Taken together, our results suggest that C. ternata and its active compounds can be used to control plant diseases.

Antibacterial Activity of Pinus densiflora Leaf-Derived Components Toward Human Intestinal Bacteria

  • Hwang, Young-Hee;Lee, Hoi-Seon
    • Journal of Microbiology and Biotechnology
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    • v.12 no.4
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    • pp.610-616
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    • 2002
  • The growth-inhibiting effects of Pinus densiflpora leaf-derived materials on nine human intestinal bacteria were investigated using the impregnated paper disk method, and their activities were compared with those of 13 commercially available terpenes. The biologically active constituent of the extract of P densiflora leaf was characterized as the monoterpene (1R)-(+)-$\alpha$-pinene by various spectroscopic analyses. Responses varied according to bacterial strain, chemicals, and dose. At 10 mg/disk, limonene and (1R)-(+)-$\alpha$-pinene strongly inhibited the growth of Clostridium perfringens, Staphylococcus aureus, and Escherichia coli, without adverse effects on the growth of five lactic acid-bacteria (Bifidobacterium adolescentis, B. bifidum, B. longum, Lactobacillus acidophilus, and L. casei). Little or no inhibition against seven bacteria was observed with anethole, borneol, camphor, caryophyllene, 1,8-cineole, estragole, linalool, and $\alpha$-terpineol. Structure-activity relationship revealed that (1R)-(+)-$\alpha$-pinene had more growth-inhibiting activity against C. perfringens than (1R)-(+)-$\beta$-, (1S-(-)-$\alpha$-, and (1S-(-)-$\beta$-pinenes. Furthermore, the growth-inhibition against L. casei was much more pronounced in (1R)-(+)-$\beta$- and (In-(-)-$\beta$-pinenes than (1R)-(+)-$\alpha$- and (1S)-(-)-$\alpha$-pinenes. These results indicate that the (+)-$\alpha$ form seems to be required against C. perfringens and $\beta$ form against L. casei for growth-inhibiting activity. Morphologically, most strains of C. perfringens were damaged and disappeared at 5 and 2 mg/disk of (1R)-(+)-$\alpha$-pinene. Morphological study revealed that (1R)-(+)-$\alpha$-pinene had more growth-inhibiting activity against C. perfringens than (1R)-(+)-$\beta$-, (1S)-(-)-$\alpha$-, and (1S)-(-)-$\beta$-pinenes. As naturally occurring growth-inhibiting agents, the Pinus leaf-derived materials described above could be useful preventive agents against diseases caused by harmful intestinal bacteria such as clostridia.

Preliminary Evaluation of the Activity Concentration Limits for Consumer Goods Containing NORM

  • Jang, Mee;Chung, Kun Ho;Ji, Young Yong;Lim, Jong Myung;Kang, Mun Ja;Choi, Guen Sik
    • Journal of Radiation Protection and Research
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    • v.41 no.2
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    • pp.101-104
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    • 2016
  • Background: To protect the public from natural radioactive materials, the 'Act on safety control of radioactive rays around living environment" was established in Korea. There is an annual effective dose limit of 1 mSv for products, but the activity concentration limit for products is not established yet. Materials and Methods: To suggest the activity concentration limits for consumer goods containing NORM, in this research, we assumed the "small room model" surrounding the ICRP reference phantom to simulate the consumer goods in contact with the human bodies. Using the Monte Carlo code MCNPX, we evaluate the effective dose rate for the ICRP reference phantom in a small room with dimension of phantom size and derived the activity concentration limit for consumer goods. Results and Discussion: The consumer goods have about 1600, 1200 and $19000Bq{\cdot}kg^{-1}$ for $^{226}Ra$, $^{232}Th$ and $^{40}K$, and the activity concentration limits are about six times comparing with the values of building materials. We applied the index to real samples, though we did not consider radioactivity of $^{40}K$, indexes of the some samples are more than 6. However, this index concept using small room model is very conservative, for the consumer goods over than index 6, it is necessary to reevaluate the absorbed dose considering real usage scenario and material characteristics. Conclusion: In this research, we derived activity concentration limits for consumer goods in contact with bodies and the results can be used as preliminary screening tool for consumer goods as index concept.

$CO_2$ reforming using $TiO_2$/Ni catalysts prepared by atomic layer deposition

  • Kim, Dong-Wun;Kim, Kwang-Dae;Seo, Hyun-Ook;Dey, Nilay Kumar;Kim, Myoung-Joo;Kim, Young-Dok;Lim, Dong-Chan;Lee, Kyu-Hwan
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.443-443
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    • 2011
  • Atomic layer deposition (ALD) was used to deposit $TiO_2$ on Ni particles, and changes in the catalytic activity of Ni for $CO_2$ reforming of methane (CRM) were studied. In the presence of $TiO_2$ islands on Ni surfaces, the onset temperature of the CRM reaction was lower than that of bare Ni. During the CRM reaction, carbon was deposited on the surface, reducing the catalytic activity of the surface, but $TiO_2$ was able to remove the carbon deposits from the surface. When the Ni surface was completely covered with $TiO_2$, catalytic activity disappeared, indicating that tuning of $TiO_2$ coverage on Ni is important for maximizing the activity of the CRM reaction.

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Catalytic Activity of Au/$TiO_2$ and Pt/$TiO_2$ Nanocatalysts Prepared with Arc Plasma Deposition under CO Oxidation

  • Jung, Chan Ho;Kim, Sang Hoon;Sahu, Nruparaj;Park, Dahee;Yun, Jung Yeul;Ha, Heonphil;Park, Jeong Young
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.288-288
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    • 2013
  • We report the catalytic activity of Au/$TiO_2$ and Pt/$TiO_2$ nanocatalysts under CO oxidation fabricated by arc plasma deposition (APD), which is a facile dry process with no organic materials involved. Using APD, the catalyst nanoparticles were well dispersed on $TiO_2$ powder with an average particle size (2~4 nm) well below that of nanoparticles prepared by the sol-gel method (10 nm). We found that the average particle size of the dispersed gold nanoparticles can be controlled by changing the plasma discharge voltage of APD. Accordingly, the amount of loaded gold on the $TiO_2$ powder increased with increasing discharge voltage, but the specific surface area of the Au/$TiO_2$ samples decreased. As for catalytic reactivity, Au/$TiO_2$ showed a higher catalytic activity than Pt/$TiO_2$ in CO oxidation. The catalytic activity of the Au/$TiO_2$ samples showed size dependence where higher catalytic activity occurred on smaller gold nanoparticles. The study suggests that APD is a simple way to fabricate catalytically active nanocatalysts.

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Verification of Biological Activities and Tyrosinase Inhibition of Ethanol Extracts from Hemp Seed (Cannabis sativa L.) Fermented with Lactic Acid Bacteria (대마씨 발효 추출물의 생리 활성 및 미백 활성 검증)

  • Yoon, Yeo-Cho;Kim, Byung-Hyuk;Kim, Jung-Kyu;Lee, Jun-Hyeong;Park, Ye-Eun;Kwon, Gi-Seok;Hwang, Hak Soo;Lee, Jung-Bok
    • Journal of Life Science
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    • v.28 no.6
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    • pp.688-696
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    • 2018
  • Hemp seed (Cannabis sativa L.; HS), an annual herbaceous plant in the Cannabis genus, has been reported to play various biological functions in immunity increase, atherosclerosis, constipation, hyperlipidemia prevention, anti-inflammatory, and anti-cancer. In recently years, as superfood, the growing interest in the health care benefits of hemp seed has led to increased consumption. In this study, we investigated the effect of an ethanol extract of HS fermented with lactic acid bacteria (Lactobacillus plantarum KCTC 3107, L. plantarum KCTC 3108, L. brevis BHN-LAB128, L. paracasei BHN-LAB129). An antibacterial activity against Staphylococcus aureus and Bacillus cereus were 13.99 mm and 15.17 mm, respectively. The ethanol extracts of fermented hemp seed by lactic acid bacteria that the contents of total polyphenol, total flavonoid content, DPPH radical scavenging activity, SOD-like activity, and ${\alpha}$-glucosidase inhibitory activity were increased compared to non-fermented hemp seed. Also, tyrosinase inhibitory activity of the fermented hemp seed (FHS), known to melanin increasing substance was increased. In these results, we suggested that FHS have effects of anti-oxidant, ${\alpha}$-glucosidase inhibitory activity, and tyrosinase inhibitory activity. Hence, we proposed that FHS has possible to development as functional foods and cosmetics.

Evaluation of the Readability of Teacher's Guide Book for Nutrition Education-Sugar, Na, Trans Fat (당, 나트륨, 트랜스 지방 교재의 교사용 지도서 지문의 난이도 평가)

  • Lee, Young-Mee;Kim, Jin-Ah
    • Korean Journal of Community Nutrition
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    • v.15 no.5
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    • pp.648-655
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    • 2010
  • This study is attempted to propose a quality evaluation method of the materials for nutrition education by applying readability test of printed materials for nutrition education. It is significantly important for the teaching class with nutrition education materials to consider students understanding level and education materials topics or choosing words in developed printed materials. This study performed an evaluation of the readability of text in teachers' guidebook, which is devised for elementary school students' education material about sugar, sodium and trans-fat and attempted to estimate the developing materials through analyzing difficulty level of the text. We utilized "The Teacher's Guidebook for Cooking Activity" that had been developed for elementary school by Ministry Education Science and Technology, as the readability evaluation standard. Compared with the average score of readability about "The Teacher's Guidebook for Cooking Activity", $72.94{\pm}6.85$, "Sugar Guidebook" was 70.94{\pm}7.46, "Sodium Guidebook" was $68.76{\pm}14.50$, and "Trans-fat Guidebook" was $58.87{\pm}10.79$. Considering the subjects careers or ages, "The Teacher's Guidebook for Cooking Activity" has little deviation by the subjects careers or ages and was "intermediate" or "easy" level; however, "Sugar Guidebook", "Sodium Guidebook", "Trans-fat Guidebook" was "intermediate" or "difficult" level (p < 0.05). Readability score was especially low when the contents of some particular subjects were too professionalized or scientific terms were frequently used, and thes results were definitely seen in the "Sodium Guidebook" and "Trans-fat Guidebook". With Cloze test score, the readability evaluation will be using as an evaluation tool for the nutrition education materials.

Incorporation of Antibacterial Natural Extract into Layered Double Hydroxide through Memory Effect for Antibacterial Materials (금속이중층수산화물의 메모리효과를 이용한 항균 천연소재의 담지 및 항균소재의 개발)

  • Kim, Hyeong-Jun;Jeong, Do-Gak;O, Je-Min
    • Ceramist
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    • v.22 no.3
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    • pp.301-315
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    • 2019
  • We prepared hybrids between layered double hydroxide (LDH) and natural plant extract such as Peaonia suffruticosa Andrews (PS) and Peaonia Japonica (PJ) which was confirmed anti-bacterial activity through paper disc diffusion assay. According to X-ray diffractometer, scanning electron microscope, zeta-potential measurement and quantification of extract loading amount in hybrids, we confirmed that similar amount of PS and PJ loaded on inter-particle pore of LDH with partial adsorption on surface of LDH through reconstruction process. We also evaluated the bacterial colony forming inhibition of PS extract, PJ extract, PS-LDH and PJ-LDH hybrids against Escherichia coli as gram negative bacterium and Bacillus subtilis as gram positive bacterium, suggesting that both hybrids have enhanced anti-bacterial activity compared with extract itself.

Antimicrobial Dyeing of Cotton and Silk Fabrics Using Houttuynia cordata Extract (어성초 추출물을 이용한 면과 견직물의 항미생물성 염색)

  • Kim, Sung-Jin;Kim, Byoung-Jin;Kim, Eun-Ji;Jung, Hee-Seon;Jang, Jinho
    • Textile Coloration and Finishing
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    • v.27 no.3
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    • pp.194-201
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    • 2015
  • Cotton and silk fabrics were dyed with Houttuynia cordata extract using aqueous ethanol solution and the dyeing and post-treatment conditions were optimized to impart antimicrobial activity to the fabrics. The dried Houttuynia cordata can be extracted at $80^{\circ}C$ for 3 hours using an aqueous ethanol solution containing 70%(w/w) ethanol. For the highest color yields. Both cotton and silk fabrics can be dyed at $100^{\circ}C$ for 60min with 10g/L of NaCl under pH 4. Silk fabrics can be dyed to higher K/S than cotton fabrics. The color fastness properties of the dyed fabrics were good when either citric acid crosslinking or aluminum alum mordanting was carried out as a post treatment. The dyed silk and cotton fabrics with the post treatments showed excellent antimicrobial activity against both Staphylococcus aureus and Klebsiella pneumoniae.