• Advances in Traditional Medicine
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• v.8 no.3
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• pp.228-235
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• 2008

This study was conducted to evaluate the estrogen activity of silkworm (Bombyx mori) pupa extracts and their fractions. Powdered samples of freeze-dried silkworm pupa were extracted at room temperature (RT), $40^{\circ}C$, $60^{\circ}C$, $80^{\circ}C$, and $100^{\circ}C$ in water (D.W), chloroform, ethyl acetate, and methanol for 6h and then filtered (0.45 um). The extracts were then freeze-dried. The estrogenic activity of these extracts was then investigated by competition binding assays using estrogen receptor ${\alpha}\;(ER{\alpha})$ and $ER{\beta}$, and by evaluating their effects on the proliferation of the human breast cancer cell line, MCF-7. Among the extracts evaluated, water extracts prepared at RT showed the highest binding affinity to $ER{\alpha}$ ($IC_{50}$, 1.76 ug/ml) and $ER{\beta}$ ($IC_{50}$, 0.07 ug/ml). In addition, MCF-7 cells that were treated with 62.5 ug/ml of the RT extract showed the greatest increase in proliferation (2-fold; 1291.79%) when compared to control cells (659.82%). Next, the water extract that was prepared at RT (sample 1) was dissolved in D.W. and further fractionated using a Dowex 50W - 8X ($H^+$) column. The flow-through and wash were then pooled together and freeze-dried (sample 2). The bound materials were then eluted with 20 mM NaCl, after which they were applied to a Dowex 1X2 - 200 ($Cl^-$) column and washed with D.W. to remove the sodium ions. The eluants were then freeze-dried (sample 3). Of these fractions, sample 2 showed the highest binding affinity to ER{\alpha} ($IC_{50}$, 1.44 ug/ml) and $ER{\beta}$ ($IC_{50}$, 1.18 ug/ml). In addition, MCF-7 cells that were treated with sample 2 (15.6 ug/ml) showed the largest increase in growth (1159.39%) when compared to control cells (525.26%). Taken together, these results suggest that the fraction of the RT water extract of silkworm pupa referred to as sample 2 may be useful as a phytoestrogen.

• Journal of radiological science and technology
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• v.36 no.3
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• pp.193-200
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• 2013

There are many concerns about radiation exposure in Korea after Fukushima Nuclear Plant Accident on 2011 in Japan. As some isotope materials are detected in Korea, people get worried about the radioactive material. In addition, the mass media create an air of anxiety that jump on the people's fear instead of scientific approach. Therefore, for curbing this flow, health, medical institute from the world provide a variety of information about medical radiation safety and hold the campaign which can give people the image that medical radiation is safe. At this, the Korean Food and Drug Administration(KFDA) suggested that make the alliance of medical radiation safety and culture on August, 2011. Seven societies and institutions related medical radiation started to research and advertise the culture of medical radiation safety in Korea. In this report, mainly introduce the activities of the Korean Alliance for Radiation Safety and Culture in Medicine(KARSM) for spreading culture of medical radiation safety from 2011 to 2012.

• Journal of Bio-Environment Control
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• v.20 no.1
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• pp.21-26
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• 2011

Differences among cultivars, conditions of nutrient solution, nursing materials, and soilless culture systems were investigated to select suitable cultivar and cultivation methods for stable production of summer spinach in the highlands. The 'Quinto' spinach showed the earliest growth and highest yield. For yield increase of summer spinach, optimal solution pH was 6.0, EC was $2.0dS{\cdot}m^{-1}$, and $NH_4-N$ ratio of nutrient solution was 30 percent Stand rate of spinach in nursing seedlings, at 200-cell-tray filled with mixed nursing soil (peat : perlite = 7 : 3), was higher than those grown in urethane sponge and rock-wool plug. Yield was also 18 to 24 percent higher than those in rock-wool plug and urethane sponge. Plant length and yield of spinach in mixed substrate (peat : perlite = 7 : 3) filled nutrient film technique (MSNFT) system were longer of 18 percent, and higher of 9 percent than those in deep flow technique (DFT) system, respectively. However, changes of root zone temperature, pH and EC showed similar pattern with DFT. Therefore, growing 'Quinto' cultivar at 6.0 of pH, $2.0dS{\cdot}m^{-1}$ of EC, 30 percent of $NH_4-N$ ratio, at 200-cell-tray filled with mixed nursing soil, and MSNFT cultivation system, was the best for production of summer spinach in the highlands.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.9 no.2
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• pp.73-82
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• 1989

When the flood occurs in the alluvial rivers, the rivers adjust to the flood by means of the mechanism of the river bed variations and its morphological changes to pass that safely, the numerical model was developed to simulate the process of the alluvial river bed variation due to flood wave and carried out by the flood routing for flood wave and the sediment routing for river bed variation. The flood wave, river bed variation, and bed material size distribution may be analysed and predicted by this model. The ability of this model to predict the process of river bed response was proved by the application to the reach from Paldang dam to Indogyo site. In view of the flood analysis considering the sediment process, the effects of river bed variation for the flood routing may be negligible because the river bed variation is smaller than the unsteady flow variation during the same period. By the application of this model, it is shown that, in occurring of sequential flood events, the variation of the river bed and bed material size distribution due to flood wave is more dependent on the first flood event than the latter flood events, and that the river bed variation in this reach of the downstream Han river is dependent on the degradation and the coarsening of bed materials.

• Korean Journal of Soil Science and Fertilizer
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• v.43 no.2
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• pp.237-241
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• 2010

Many policies have been implemented to mitigate the greenhouse gases in atmosphere overall of sectors. With considering the distinct characteristics of the food security, agricultural sector is no exception to this situation. To this regard, total amount of carbon which is emitted through all of the agricultural production process is calculated, and being based on this result, the demand for the introduction of agricultural production system with low carbon has been rising. Case studies on the application of life cycle assessment (LCA) technique to agricultural sector are found in many countries. For example, life cycle inventory (LCI) data bases of crop, farm infrastructure, fertilizer, farm machinery, and etc., have been constructed and provided by Ecoinvent (Swiss centre for life cycle inventories) of Swiss. In Japan, Top-down typed LCA methodology for agriculture is developed based on the inter-industry analysis, and is evaluated according to the productive method of crop. On the other hand, environmental impact assessment of agricultural system using LCA in Korea is just in the beginning stages. So it is required to assess environmental impact on agricultural fertilizer and pesticide, and to develop their flow modeling, and methodology of LCA of agricultural sector. Environmental impact assessment on agricultural materials, machinery, and infrastructure will also be carried out.

• Journal of The Korean Society of Agricultural Engineers
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• v.60 no.2
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• pp.75-84
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• 2018

Thermal stress of livestock has been issued due to recent climate change trends and this causes reproductive disorders, decreased feed consumption, immunosuppression, and increased mortality of animals. Concept of THI has been widely used to quantitatively evaluate the degree of thermal stress for animals, however use of this concept is restricted for animals living in the enclosed facilities such as mechanically ventilated broiler houses. In this study, time-based internal energy flow and variation trends of temperature and humidity were analyzed based on BES technique. Local weather data, insulation characteristics of building materials, heat and moisture generation rate from broilers according to age, algorithm of ventilation operation were adopted for boundary condition of the model to accurately compute THI values inside the mechanically ventilated broiler house. From the BES computation, excess frequency of THI threshold in Jeju city was highest on the assumption that air conditioning equipments were not installed. When general raising density ($39kg\;m^{-2}$) was adopted, total 2,191 hours were exceeded. Excess hours of THI threshold were strongly related to the cumulative air temperature ($R^2=0.87$).

• Archives of design research
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• v.15 no.4
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• pp.263-274
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• 2002

This study aims to analyze the image of long-span structures. For the intention, it analyzes the relationship between images and physical attributions of elements such as materials, stresses, configurations, compositions and shapes of structures. The image of structures can represent following 5 factors; friendly-unfriendly, strong-weak, dynamic-calm, superior-inferior, and regular-irregular. The friendly-unfriendly in the image of structure mostly determines on a finished material and partly with a structural shape. The strong-weak in the image of structure determines on configuration of the structural members. The dynamic-calm in the image of structure determines on the structural shape. Hence the structure has dynamic forms when it seems to be open and sharp, namely when it receives the flow of forces in the structural shape, and it has a (-) gauss curved rate or an diagonal appearance. The superior-inferior in the image of structure determines on composition of structural elements. The structure seems to be superior is contributed not simply to support load but positively to create design as a tectonic element. From now on, this study can provide the useful information on the long-span structure design through the more appropriate analysis of the image.

• Korean Journal of Environmental Biology
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• v.36 no.1
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• pp.90-97
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• 2018

This study assessed the effect of ozone to control pathogenic bacteria in inlet water flowing to flounder farms, establishing operational parameters of ozonation at seawater conditions. Hydraulic retention time in a reaction pipeline after ozonation was fixed at 3 minutes in a flow through system. Concentrations of total residual oxidant (TRO) by ozonation were measured according to different ozonation intensities. The oxidant reduction potential (ORP), which is indirect but enables real-time measurement, was measured in relation to TRO values. TRO values were $0.01{\pm}0.01mg\;L^{-1}$ at an ORP range of 320-410 mV, $0.07{\pm}0.02mg\;L^{-1}$ at 600 mV, and $0.16{\pm}0.03mg\;L^{-1}$ at 700 mV. A heterotrophic marine bacteria colony was reduced by 80.6-97.9%, showing the suppression effect of ozonation on total bacteria in inlet water. At an ORP range of 400-500 mV, colonies of heterotrophic marine bacteria, Vibrio spp., and gram negative bacteria were significantly reduced in outlet water from a culture tank with ongrowing flounder (230 g) at a stocking density of $8kg\;m^{-2}$. Especially, Vibrio spp. and gram negative bacteria were seldom found at 400-500 mV. The daily feeding rate was from over 0.7% to total body weight at 300-500 mV, showing better performance than that in the control. The pathogenic bacteria entering the flounder farm were effectively removed when the ORP range to 400 mV or less.

• The Journal of Engineering Geology
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• v.9 no.1
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• pp.31-43
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• 1999

This study aims to quantify the distribution characteristics of the fracture system for the numerical modeling of groundwater flow in the north-eastern area of Yosu peninsula. The study area is composed mainly of volcanic rocks and granite. The regional and site scale lineament in the range of magnitude Order 1 to Order 3 were analyzed from the geologic map, air-photograph and shaded relief map. The geometric parameter of Order 4 fracture system was acquired from the scanline survey on the ground surface. There is a similar trend in the preferred orientation between the regional lineament and the Order 4 fracture system except the Set 4 of Order 4 fracture system which is not prominent in the type. That is classified to three fracture sat of high dip angle and one of ow dip angle. From the lineament trend. The orientation of Order 4 fracture system has similar characteristics in each rock termination mode analysis, it is considered that the fracture system was developed systematically and sequentially from Set 1 to Set 4 Filling materials are distinct relatively in low dip angle set. The fracture spacing follows to lognoral distribution and the fracture frequency corrected by the modified Terzaghi correction ranges from 0.38 to 1.01 per mater in each fracture set. The fracture trace lenght also follows to lognormal distribution and ranges from 2.9m to 3.7m in each fracture set.

• Journal of Environmental Impact Assessment
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• v.16 no.6
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• pp.467-483
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• 2007

Environmental Impact Assessment (EIA) is a kind of planning technique to seek ways to minimize environmental impact, a scheme to encourage sustainable development. With the launch of the Ministry of Environment in 1980, the EIA was introduced in Korea. Its full operation was initially driven by regulations on documenting EIA reports in 1981, which was piloted as a decision-making scheme where final decision were made at the development department after considering opinions suggested by the Ministry of Environment. At that time, dominance of the economic logic overwhelmed environ-friendly opinions, but thanks to the fourth revision of the Environmental Conservation Law in 1986, private projects came to be included on the EIA list. This was a turning point for the EIA to become a regulatory system. Local governments are also conducting the EIA regardless of the national-level EIA. In order to prevent and resolve increasingly severe environmental problems in Seoul in advance due to various construction projects, the Seoul Metropolitan Government, for the first time as a local government in Korea, legislated city decrees to introduce the EIA which has been underway from September 1, 2002. In particular, the Seoul government, unlike the Ministry of Environment, has included construction works on the list of evaluation projects, adopting the scoping and screen procedure scheme. In addition, complementing operational setbacks, the city government has revised and implemented decrees and enforcement laws on the Impact Assessment on Environment, Transportation and Disasters by shortening the consultation period, eliminating the submission of reports on construction, and expanding the waiver requirements in consultation over the reports. Therefore, development measures for the EIA scheme of the Seoul Metropolitan Government will be the target of the research. To that end, the up-to-date data of the Ministry of Environment, the Seoul government and local governments was collected, and latest materials from the EU, previous research and the Internet were gathered for analyses. By doing so, the flow of the EIA was reviewed, and the EIA schemes of local governments under the national EIA were analyzed. Furthermore, based on the Seoul government's recent data on the EIA based on the decrees, the background and legislation of the Seoul government's EIA were analyzed along with the developments for the environmental organizations. Setbacks were derived from the implementation period, evaluation procedures, consultation period and details of the EIA, and corresponding development measures were proposed.