• 한국식품영양학회지
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• 제30권2호
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• pp.371-377
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• 2017

Muscle atrophy is characterized by a decrease in the mass of the muscle. With an increase in life expectancy and chronic illnesses, the incidence of muscle atrophy is increasing and the quality of life of patients is decreasing. Thus, reducing muscle atrophy is of high clinical and socio-economic importance. Mistletoe is a semi-parasitic plant that has been used as a traditional medicine in many countries to treat various human illnesses. It has been reported that Korean mistletoe extract (KME) has diverse biological functions including anti-tumor, anti-oxidant, anti-diabetic, anti-obesity properties, and extension of lifespan. Especially, we have recently reported that KME improves exercise endurance in mice, indicating its beneficial roles in enhancing the capacity of skeletal muscle. In this study, we investigated whether KME could activate the signaling pathway related to protein synthesis in a mouse model of muscle atrophy. Interestingly, KME efficiently activated the Akt/mTOR pathway, and Akt and mTOR are important signaling hub molecules for the acceleration of protein synthesis in muscle cells. In addition, KME also increased the activity of S6 kinase which is involved in the regulation of muscle cell size. Moreover, the ERK activity, required for transcription of ribosomal RNA for protein synthesis, was also enhanced in KME-treated mouse muscle. These data support the idea that KME increases muscle mass via increased protein synthesis. Our findings also suggest that Korean mistletoe might be a promising candidate for the development of functional foods that are beneficial for preventing muscle atrophy.

• 한국소음진동공학회논문집
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• 제25권12호
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• pp.866-873
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• 2015

The transverse vibration of the deploying beam from rigid hub was analyzed by simulation and experiment. The linear governing equation of the deploying beam was obtained using the Euler-Bernoulli beam theory. To discretize the governing equation, the Galerkin method was used. After transforming the governing equation into the weak form, the weak form was discretized. The discretized equation was expressed by the matrix-vector form, and then the Newmark method was applied to simulate. To consider the damping effect of the beam, we conducted the modal test with various beam length. The mass proportional damping was selected by the relation of the first and second damping ratio. The proportional damping coefficient was calculated using the acquired natural frequency and damping ratio through the modal test. The experiment was set up to measure the transverse vibration of the deploying beam. The fixed beam at the carriage of the linear actuator was moved by moving the carriage. The transverse vibration of the deploying beam was observed by the Eulerian description near the hub. The deploying or retraction motion of the beam had the constant velocity and the velocity profile with acceleration and deceleration. We compared the transverse vibration results by the simulation and experiment. The observed response by the Eulerian description were analyzed.

• 한국강구조학회 논문집
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• 제14권6호
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• pp.765-772
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• 2002

초고층 건물의 가속도 레벨을 줄이기 위해서 TMD, TLD, VED와 같은 다양한 진동제어장치들이 많은 국내외 연구자들에 의해 연구되고 있다. TLD는 다른 제진장치에 비해 설치의 간편함 및 유지비용이 저렴한 장점이 있다. 그러나 물의 요동을 평가함에 있어서 어려움이 있으므로 동조액체댐퍼의 동적특성에 대한 실험 및 해석적 검증이 필요하다. 본 연구에서는 TLD를 100층 규모의 초고층건물에 설치할 경우를 상정하여 자유진동실험과 백색잡음을 이용한 강제진동실험을 통하여 TLD의 제진성능을 확인하고자 하였다. TLD의 질량비, 감쇠네트수, TLD 형상비 등을 주요실험변수로 설정하였으며, 물탱크를 설치한 건물의 반응값들이 건물 단독인 경우보다 적게 나타남을 알 수 있었다. 또한 질량비, 감쇠네트, 형상비가 커질수록 감쇠성능이 개선됨을 알 수 있었다.

• 기술사
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• 제17권3호
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• pp.6-21
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• 1984

A rock slide in amount of 100 tons in weight happened at 7: 10 a.m., 4th October 1982, on the southwestern ridge of Mt. Seunghag, Busan City. The original rock mass of the rock slide is located 850m west from the Dangri Crushed Stone Quarry. The geology of the area consists of agglomerate, andesite, andesitic tuff, and shale hornfels of the Cretaceous Yucheon Group. The rock blocks were first shifted along the steep joint plane on an andesite outcrop at the site and then to the eastern foot of the mountain slope where some private houses are placed. The mountain slope is covered with thick superficial soil. A slided monolithic-block with 83 tons in weight from the rock slide met with an accident of striking against a house with a tremendous force, to which much damage was done as much as its half was destroyed. The rock-slided block pierced the board-floored room only posited at the center and by the bedroom of the house making a pass like a bullet hole, and hence cut a big pine tree with 24 centimeters in diameter at a distance of 26 meters down the house. However nobody was killed or injured in the stricken house, though seven family members were stayed therein at the very time of accident. They really met a rare opportunity in an unhappy disaster. Measurements of the rock slide were made in the course of the field survey. The monolithic mass was transported by way of saltation, rolling, and sliding to a distance of 300 meters down along the slope dipping 30$^{\circ}$ east. It took about 16 seconds front tile outcrop to the terminal. The acceleration value of the monolithic rock slide is 2.35m/sec$^2$.

• 한국항해학회지
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• 제23권2호
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• pp.29-42
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• 1999

An accurate method of estimating ship maneuverability needs to be developed to evaluate precisely and improve the maneuverability of ships according to the water depth. In order to estimate maneuverability by a mathematical model. The hydrodynamic forces acting on a ship hull and the flow field around the ship in maneuvering motion need to be estimated. The ship speed new the berth is very low and the fluid flow around a ship hull is unsteady. So, the transient fluid motion should be considered to estimate the drag force acting on the ship hull. In the low speed and short time lateral motion, the vorticity is created by the body and grow up in the acceleration stage and the velocity induced by the vorticity affect to the body in deceleration stage. For this kind of problem, CFD is considered as a goof tool to understand the phenomena. In this paper, the 2D CFD code is used for basic consideration of the phenomena to solve the flow in the cross section of the ship considering the ship is slender and the water depth is large enough. The flow fields Added and hydrodynamic forces for the some prescribed motions are computed and compared with the preliminary experiment results. The comparison of the force with measurement is shown a fairly good agreement in tendency. The 3D Potential Calculation based on the Hess & Smith Theory is employed to predict the surge, sway added mass and yaw added moment of inertia of hydrodynamic coefficients for M/V ESSO OSAKA according to the water depth. The results are also compared with experimental data. Finally, the sway added mass of hydrodynamic coefficients for T/S HANNARA is suggested in each water depth.

• 한국컴퓨터정보학회논문지
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• 제16권12호
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• pp.167-174
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• 2011

본 논문에서는 차량의 CO2 배출량을 추정하기 위한 방법들을 설명하였다. 전 세계적으로 에너지와 환경의 중요성이 부각되고 있으며 자동차 부문의 기술개발에서도 이 점이 크게 강조되고 있다. 특히 CO2는 지구 온난화에 영향을 미치는 온실가스로 배출 규제 대상이 되고 있다. 차량의 주행 거리에 따른 CO2 배출량 추정 방법, 기후 변화 위원회(IPCC))에서 제시한 CO2 배출량 추정 방법, MAF(Mass Air Flow)와 옥탄의 화학반응식을 이용한 CO2 배출량 추정 방법 등에 대해서 설명하고 각각의 방법들의 성능을 비교하였다. 각각의 CO2 추정 방법들에 대한 성능을 확인하기 위해 실차를 이용하여 약 5km의 도로를 주행하면서 OBD-II 포트로 차량의 진단 정보를 획득하고, 주행 거리, 연료 소모량을 구하였다. 정속 주행에서는 비슷한 CO2 배출량 결과를 얻었고, 급가속 주행에서는 IPCC 방식과 화학반응식 방식이 보다 현실적인 배출량 결과를 보임을 확인하였다.

• 한국포장학회지
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• 제12권2호
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• pp.97-102
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• 2006

Shock and vibration inputs are transmitted from the transporting vehicle through the packaging to the fruit. The vibration causes sustained bouncing of fruits against each other and the container wall. The steady state vibration input may cause serous fruit injury, and the damage is particularly severe if the fruits are bounced at its resonance frequency. The determination of the resonance frequencies of the fruits and vegetables may help the packaging designer to determine the proper packaging system providing adequate protection for the fruits, and to understand the complex interaction between the components of the fruits when they relate to expected transportation vibration inputs. To analyze the vibration properties of the watermelon for optimum packaging design during transportation, sinusoidal sweep vibration tests were carried out. The resonance frequency of the watermelon ranged from 19 to 32 Hz and the amplitude at resonance was between 1.6 and 2.9 G. The resonance frequency and amplitude at resonance frequency band of the watermelon decreased with the increase of the sample mass. The multiple nonlinear regression equation for predicting the resonance frequency of the watermelon were developed using the independent variables such as mass, input acceleration and sphericity.

• 한국도로학회논문집
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• 제20권1호
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• pp.9-18
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• 2018

PURPOSES : In this research, the initiation and development of corrugation on a gravel road with certain wheel and boundary conditions were evaluated using a coupled discrete-element method (DEM) with multibody dynamics (MBD). METHODS : In this study, 665,534 particles with a 4-mm diameter were generated and compacted to build a circular roadbed track, with a depth and width of 42 mm and 50 mm, respectively. A single wheel with a 100-mm diameter, 40-mm width, and 0.157-kg mass was considered for the track. The single wheel was set to run slowly on the track with a speed of 2.5 rad/s so that the corrugation was gradually initiated and developed without losing contact between the wheel and the roadbed. Then, the shape of the track surface was monitored, and the movement of the particles in the roadbed was tracked at certain wheel-pass numbers to evaluate the overall corrugation initiation and development mechanism. RESULTS : Two types of corrugation, long wave-length and short wave-length, were observed in the circular track. It seems that the long wave-length corrugation was developed by the longitudinal movement of surface particles in the entire track, while the short wave-length corrugation was developed by shear deformation in a local section. Properties such as particle coefficients, track bulk density, and wheel mass, have significant effects on the initiation and development of long-wave corrugation. CONCLUSIONS : It was concluded that the coupled numerical method applied in this research could be effectively used to simulate the corrugation of a gravel road and to understand the mechanism that initiates and develops corrugation. To derive a comprehensive conclusion for the corrugation development under various conditions, the driver's acceleration and deceleration with various particle gradations and wheel-configuration models should be considered in the simulation.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2009년도 한국우주과학회보 제18권2호
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• pp.34.1-34.1
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• 2009

After SNIa and WMAP observations during the last decade, the discovery of the accelerated expansion of the universe is a major challenge to particle physics and cosmology. There are currently three candidates for the dark energy which results in this accelerated expansion: $\cdot$ a non-zero cosmological constant, $\cdot$ a dynamical cosmological constant (quintessence scalar field), $\cdot$ modifications of Einstein's theory of gravity. The scalar field model like quintessence is a simple model with time-dependent w, which is generally larger than -w1. Because the different w lead to a different expansion history of the universe, the geometrical measurements of cosmic expansion through observations of SNIa, CMB and baryon acoustic oscillations (BAO) can give us tight constraints on w. One of the interesting ways to study the scalar field dark-energy models is to investigate the coupling between the dark energy and the other matter fields. In fact, a number of models which realize the interaction between dark energy and dark matter, or even visible matter, have been proposed so far. Observations of the effects of these interactions will offer an unique opportunity to detect a cosmological scalar field. In this talk, after briefly reviewing the main idea of the three possible candidates for dark energy and their cosmological phenomena, we discuss the interactinng dark-energy model, paying particular attention to the interacting mechanism between dark energy with a hot dark matter (neutrinos). In this so-called mass-varying neutrino (MVN) model, we calculate explicitly the cosmic microwave background (CMB) radiation and large-scale structure (LSS) within cosmological perturbation theory. The evolution of the mass of neutrinos is determined by the quintessence scalar field, which is responsible for the cosmic acceleration today.

• 한국CDE학회논문집
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• 제19권4호
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• pp.324-331
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• 2014

In the design of a combat vehicle, various performances such as firepower, mobility and survivability, etc., should be considered. Furthermore, since these performances relate to each other, design framework which can treat an integrated system should be employed to design the combat vehicle. In this paper, we use empirical interior ballistic and 3D combat vehicle analyses for predicting firepower and mobility performances which are developed in previous study (1) integrated performance modeling. In firepower performance, pitch and roll angle by sequential firing are considered. In mobility performance, vertical acceleration after passing through a bump is regarded. However, since there are many design variables such as mass of vehicle, mass of suspension, spring and damping coefficient of suspension and tire, geometric variables of vehicle, etc., for firepower and mobility performance, we utilize analysis of variance and quality function deployment to reduce the number of design variables. Finally, integrated design optimization is carried out for integrated performance such as firepower and mobility.