• 한국시스템다이내믹스연구
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• 제15권1호
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• pp.75-96
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• 2014

This research primarily aims at analyzing major crises originating from marginalizing population, especially in counties. In addition, based on the system dynamics approaches, it pays attention to divulging causal loop structure which has been rather strengthened by diverse interactions among key variables. Judging from simulation works, even though Korea is exposed to unprecedented aging trends over decades, its counter response seems inadequate and insufficient, mostly dismissing a series of impact embedded in the aging dynamics. This research statistically confirms that demographic marginalization trends have already begun in the villages within Eup and Myon counties. Furthermore, this research pinpoints out the fact that it would be almost impossible for majority of villages within Eup and Myon counties to escape from going out of existence in the course of time, as they tend to be entrapped vicious cycle of marginalization or extinction.

• Agribusiness and Information Management
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• 제8권1호
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• pp.1-10
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• 2016

Information and communication technologies (ICTs) have always mattered in agriculture too. In day-to-day practices of agriculture and allied sectors, the farmers often share their information. Changing weather patterns, soil conditions, pests and diseases always throw challenges to small and marginal farmers. So, the farmer needs up-dated information to cope with and even benefit from these changes. In the developing countries like India, where agriculture still plays a crucial role (over 58% of the rural households depend on agriculture as their livelihood) and the rising population from 1027 million to 1419 million during 2001-16 (a total rise of 38 percent or 1.3 percent per year) pose a lot of pressure on land and other resources to meet the food security needs on one hand and to meet the challenges of globalization on the other. Understanding and addressing these challenges are very crucial, in which ICT can play a major role. With the booming mobile, wireless, and Internet industries, ICT has found a foothold even in poor marginal and smallholder farms and in their activities. The survey conducted among the 120 farmers in Srikakulam district in India revealed that, ICT has revolutionized the agriculture in the modern days. Production and marketing information is accessed by 91% of the sample farmers through mobile in 2015, where it was only 5% in 2005. The extent of use of mobile phones by the farmers varied with the decision to be taken by them like Harvesting, packing, and storing (94%), Selling Decision (91%), Seed purchase (89%), Application of fertilizers and pesticides (88%) and Land preparation and planting (84%), other package of practices (77%). The farmers further opined that, 'Voice' was the dominating source of communication (96%) compared to Short Message Service (SMS) (only 27%) and Internet access (10%), as majority are illiterate. The use of camera (71%), Bluetooth (33%), Radio (61%) TV (41%) are the other means of sharing the information. In this context of importance of ICTs in Indian agriculture, greater attention justifies about the applications of ICT's to alleviate poverty and promote economic growth of the farming population.

• Journal of Preventive Medicine and Public Health
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• 제21권1호
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• pp.82-88
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• 1988

The main objectives of this study were to know the prevalence of cerebrovascular diseases, to find the important risk factors of cerebrovascular diseases. This study is a part of Eumseong Community Health Project supportes by GTZ(West German Goverment). 116 perceived cases of cerebrovascular diseases were first screened by health interview and examinations and 80 cases were diagnosed as a cerebrovascular group. For comparison, 80 cases were matched with their neighbor controls of the same sex and the similar age. 1. The prevalence rate for cerebrovascular diseases was 476.3 per 100,000 population which is considered to be very high compared with that of other countries. Age adjusted rate for cerebrovascular diseases was 261.6 per 100,000. 2. Among the risk factors examined for the association with cerebrovascular diseases by case-control study, and analysed by paired marginal test(McNemar's $X^2$-test) and odds ratio, only hypertension showed high significant statistical association.

• Animal Systematics, Evolution and Diversity
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• 제34권1호
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• pp.37-49
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• 2018

Two hypotrich ciliates, Australocirrus shii (Shi et al., 1997) Kumar & Foissner, 2015 and Afrokeronopsis aurea (Foissner & Stoeck, 2008) Foissner et al., 2010 isolated from freshwater habitats in Korea and were studied based on the specimens from live and after protargol impregnation. Australocirrus shii is redescribed based on morphology and 18S rRNA gene sequence, whereas Af. aurea is the first record for Korea. Main morphological features of the Korean population of Au. shii are as following: body size $100-200{\times}40-80{\mu}m$ in vivo; elongate to ellipsoidal or slightly elongate obovate, dorsoventrally flattened; transverse cirri arranged in (3+2) pattern, anterior pretransverse ventral cirrus distantly anterior of the first transverse cirrus; eight or nine dorsal kineties; and three caudal cirri. Main morphological features of the Korean population of Af. aurea are as following: body size $230-375{\times}70-145{\mu}m$ in vivo; shape elongate obovate or ellipsoidal, widest at the mid-body; undulating membranes in Australocirrus pattern with a buccal depression; and three caudal cirri. The Korean population of A. shii is similar in morphology with previous descriptions except for the presence of indentation at the posterior end in the Korean population. The Korean population of A. aurea is slightly shorter than the South African population and has slightly less marginal and mid-ventral cirri. The phylogenetic analysis of present two Korean hypotrichs and relevant species based on 18S rRNA gene sequences generated almost similar tree topologies compared with previous studies.

• 국토계획
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• 제54권3호
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• pp.15-26
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• 2019

The development of science and transportation technology leads to the increase of inter - city networks that play an important role in urban growth. Overall, numerous studies based on network theory pay attention to positive effects of urban network on urban growth. However, some studies have pointed out the negative effects of inter-city interactions such as straw effects. This implies that the network between cities may not be positively correlated with urban growth, and that the direction of the influence may vary from a certain threshold, such as the marginal utility curve. In this context, the purpose of this study is to measure the impacts of network with central city on urban growth in the capital region and examine the relationship between urban network and growth. Two multiple regression models are employed with changes in population and employment as dependent variables. The urban network index and other control variables are used as independent variables. Especially, the urban network indexes are used in quadratic forms to examine non linear relations with urban growth such U-shape or an inverted U-shape. The results show that the relationships between networks with the central city and urban growth are not a simple linear, and the influence can be changed from the critical point.

• 한국임상약학회지
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• 제21권2호
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• pp.74-80
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• 2011

Population pharmacokinetics for gentamicin were compared with 20 Korean patients (14 male and 6 female) and 25 Caucasian appendicitis patients (16 male and 9 female). Two to six blood specimens were collected from all patients at the following times : just before a regularly scheduled infusion and at 0.5 hour after the end of a 0.5 hour infusion. Nonparametric expected maximum(NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant(K), the slope(KS) of the relationship between K versus creatinine clearance(Ccr), the apparent volume of distribution (V), the slope(VS) of the relationship between V versus weight, gentamicin clearance(CL) and the slope(CS) of the relationship between CL versus Ccr and the V. The output includes two marginal probability density function(PDF), means, medians, modes, variance, skewness, kurtosis, and CV%. The mean K(KS) were$0.402{\pm}0.129hr^{-1}$ ($0.00486{\pm}0.00197[hr{\cdot}mL/min/1.73m^2]^{-1}$) and $0.425{\pm}0.137hr^{-1}$($0.00432{\pm}0.00168[hr{\cdot}mL/min/1.73m^2]^{-1}$) for Korean and Caucasian populations, respectively. The mean V(VS) were not different at $14.3{\pm}3.69L$($0.241{\pm}0.0511L/kg$) and $15.8{\pm}4.81L$($0.236{\pm}0.0531L/kg$) for Korean and Caucasian populations, respectively (P>0.2). The mean CL(CS) were $5.68{\pm}1.69L/hr$ ($0.0714{\pm}0.0222L/kg[hr{\cdot}mL/min/1.73m^2]$) and $6.29{\pm}1.84L/hr$ ($0.0629{\pm}0.0189L/kg[hr{\cdot}mL/min/1.73m^2]$) for Korean and Caucasian populations, respectively. There are no differences in gentamicin pharmacokinetics between Korean and Caucasian appendicitis patients.

• 약학회지
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• 제56권1호
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• pp.48-54
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• 2012

Enviromental differences in gentamicin pharmacokinetics by using population pharmacokinetic methods were compared with 20 Korean patients and 24 Korean-American appendicitis patients. Two to six blood specimens were collected from all patients at the following times : just before a regularly scheduled infusion and at 0.5 hour after the end of a 0.5 hour infusion. Nonparametric expected maximum (NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant (K), the slope (KS) of the relationship between K versus creatinine clearance ($C_{cr}$), the apparent volume of distribution (V), the slope (VS) of the relationship between V versus weight, gentamicin clearance (CL) and the slope (CS) of the relationship between CL versus $C_{cr}$ and the V. The output includes two marginal probability density function (PDF), means, medians, modes, variance and CV%. The mean K (KS) were $0.402{\pm}0.129\;h^{-1}(0.00486{\pm}0.00197\;[h{\cdot}ml/min/1.73\;m^2]^{-1})$ and $0.411{\pm}0.135\;h^{-1}(0.00475{\pm}0.00180\;[h{\cdot}ml/min/1.73\;m^2]^{-1})$ for Korean and Korean-American populations, respectively. The mean V (VS) were not different at $14.3{\pm}3.6l(0.241{\pm}0.0511l/kg)$ and $15.1{\pm}3.84l(0.239{\pm}0.0492l/kg)$ for Korean and Korean-American populations, respectively (p>0.2). The mean CL (CS) were $5.68{\pm}1.69l/h(0.0714{\pm}0.0222l/kg[h{\cdot}ml/min/1.73\;m^2])$ and $5.70{\pm}1.77l/h(0.0701{\pm}0.0215l/kg[h{\cdot}ml/min/1.73\;m^2])$ for Korean and Korean-American populations, respectively. There were no enviromental differences in gentamicin pharmacokinetics between Korean and Korean-American appendicitis patients.

• 약학회지
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• 제39권2호
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• pp.103-112
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• 1995

Population pharmacokinetics for gentamicin were compared with 24 American patients (16 male and 8 female) and 16 Korean-American appendicitis patients(12 male and 4 female). Two to six blood specimens were collected from all patients at the following times: just before a regularly scheduled infusion and at 1/2 hour after the end of a 1/2 hour infusion. Nonparametric expected maximum(NPEM) algorithm for population modeling was used. The estimated parameters were the elimination rate constant(K), the slope of the relationship between K versus creatinine clearance(KS), the apparent volume of distribution(V), the slope of the relationship between V versus weight(VS), gentamicin clearance(CL) and the slope of the relationship between CL versus creatinine clearance and the VS(CS). The output includes a 3-dimensional plot of the joint probability density function(PDF), two marginal PDF, means, medians, modes, variance, skewness, kurtosis, and CV%. The mean K(KS) were 0.424$\pm$0.139(0.00429$\pm$0.00164) and 0.411$\pm$0.135 hr$^{-1}$ (0.00475$\pm$0.00180[hr.mL/min/1.73m$^{2}]^{-1}$) for American and Korean-American populations, respectively. The mean V(VS) were not different at 15.6$\pm$4.77(0.233$\pm$0.0526) and 15.1$\pm$3.84L(0.239$\pm$0.0492 L/kg) for American and Korean-American populations, respectively (P>0.2). The mean CL (CS) were 6.28$\pm$1.85(0.0634$\pm$0.0191) and 5.70$\pm$1.77 L/hr(0.0701$\pm$0.0215 L/kg[hr.mL/min/1.73m$^{2}$)] for American and Korean-American populations, respectively. There are no differences in gentamicin pharmacokinetics between American and Korean-American Appendicitis patients.

• Animal cells and systems
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• 제8권1호
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• pp.41-47
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• 2004

The kallikrein-kinin system affects regulation of blood pressure, and genes encoding for the components of this system have been considered as good candidates for hypertension. To evaluate the relationship between genetic polymorphisms of candidate genes involved in this system and hypertension, we performed case-control studies using genetic markers in Korean normotensives and hypertensives, respectively. By association study, there was a marginal association with hypertension in AA genotype distribution of A1789G polymorphism in the hKLK1 gene (P=0.0754). Thus, this genetic polymorphism may weakly contribute to the susceptibility to hypertension in Koreans. We also observed that significant linkage disequilibrium exists among three polymorphic sites in the hKLK1 gene studied, suggesting that the three genetic polymorph isms can be useful as genetic markers in clinical association studies. Further studies using larger sample sizes and more genetic markers will be needed to clarify genetic influence of kallikrein-kinin system for hypertension.

• 자원환경지질
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• 제11권2호
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• pp.81-88
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• 1978

Nearly 300 bottom sediments and 20 box-cores were sampled from the Asan bay. The central portion of the Asan bay is covered by sand, slightly gravelly sand and gravelly muddy sand. Between the central and marginal zones gravelly mud and slightly gravelly sandy mud are characteristically distributed. The gravel population in the sediments seems to be originated from the rocky bottom on the area near the bay because the gravel is angular and composed of the schist and gneiss. The quartz/feldspar ratio is about 3/2. It is considered to be that the amount of feldspar in this bay is much higher than that of any other areas in the Yellow Sea. This is considerd to be comparatively short distance of transport ion of these sediment from the provenance.