• Steel and Composite Structures
• /
• 제36권4호
• /
• pp.481-492
• /
• 2020

To study the rail mapped deformation caused by the pier settlement of simply - supported bridges with China Railway Track System III (CRTS III) slab ballastless track (SBT) system under the mode of non-longitudinal connection ballastless track slab, this study derived an analytical solution to the mapped relationships between pier settlement and rail deformation based on the interlayer interaction mechanism of rail-pier and principle of stationary potential energy. The analytical calculation results were compared with the numerical results obtained by ANSYS finite element calculation, thus verifying the accuracy of analytical method. A parameter analysis was conducted on the key factors in rail mapped deformation such as pier settlement, fastener stiffness, and self-compacting concrete (SCC) stiffness of filling layer. The results indicate that rail deformation is approximately proportional to pier settlement. The smaller the fastener stiffness, the smoother the rail deformation curve and the longer the rail deformation area is. With the increase in the stiffness of SCC filling layer, the maximum positive deformation of rail gradually decreases, and the maximum negative deformation gradually increases. The deformation of rail caused by the pier settlement of common-span bridge structures will generate low-frequency excitation on high-speed trains.

• Journal of Microbiology
• /
• 제35권4호
• /
• pp.277-283
• /
• 1997

Promoters inducible by paraquat, a superocide-generating agent, were isolated from Escherichia coli using a promoter-probing plasmid pRS415 with promoterless lacA gene. Twenty one promoters induced by paraquat were selected and further characterized. From sequence analysis, thirteen of the promoters were mapped to their specific loci on the Escherichia coli chromosome. Several promoters were mapped to the upstream of known genes such as usgl, katG, and mglB, whose relationships with superoxide response have not been previously reported. Other promoters were mapped to the upstream region of unknown open reading frames. Downstream of HC 96 promoter are uncharacterized ORFs whose sequences are homologous to ABC-transporter subunits. Downstream of HC84 promoter is an ORF encoding a transcriptional regulator-like protein, which contains a LysR family-specific HTH (helix-turn-helix) DNA bindign motif. We investigated whether these promoters belong to the soxRS regulon. All promoters except HC96 were found to belong to the soxRS regulon. The HC96 promoter was significantly induced by paraquat in the soxRS deletion mutant strain. The basal transcription level of three promoters (HE43, HC71, HD94) significantly increased at the stationary phase, implying that they are regulated by RpoS. However, paraquat inducibility of all promoters disappeared in the stationary phase, suggesting that SoxRS regulatory system is active only in rapidly growing cells.

• 정보기술과데이타베이스저널
• /
• 제7권1호
• /
• pp.55-65
• /
• 2000

Information semantics is a well-known issue in areas of information systems researches. It describes what data mean, how they are created, where they can be applied to ; thus, it provides indispensable information for management of data. This article proposes to formalize information semantics by the processes that data are created or transformed. A scheme is proposed to describe an information production structure, which is called an information structure graph. An information structure graph is a directed graph, whose leaves are primary input data objects and whose root and internal nodes are output objects. Information semantics is derived from an information structure graph that has data as its root. For this, rules are proposed to manipulate and compare graphs. The structural relationships among information structure graphs are mapped into semantic relationships among data.

• 한국컴퓨터정보학회논문지
• /
• 제14권1호
• /
• pp.173-181
• /
• 2009

본 논문은 온톨로지 작성에 사용되는 RDF(Resource Description Framework) 모델을 컬러 페트리 넷 모델로 변환하는 알고리즘을 제안한다. 제안하는 알고리즘은 RDF 모델의 클래스와 프로퍼티들을 컬러 페트리 넷의 플레이스로 매핑하여 RDF 모델의 의미를 컬러 페트리 넷의 토폴로지로 변환한 다음 클래스와 프로퍼티들 간의 관계를 토큰의 전이로 나타냄으로써 RDF의 문장들을 컬러 페트리 넷에 반영한다. RDF 문장들을 반영하는 기본적인 방법은 주어와 객체를 나타내는 토큰들의 순서쌍으로 구성된 토큰을 생성하여, 술어를 나타내는 자리로 전이하는 방법이다. 주어진 RDF 모델을 제안하는 방법으로 실제 CPNTools를 이용하여 컬러 페트리 넷 모델로 변환하고, RDF 질의에 대한 추론과 답을 CPNTools에서 구하는 사례를 보였다.

• Computers and Concrete
• /
• 제3권6호
• /
• pp.423-437
• /
• 2006

Stress wave propagation through concrete is simulated by finite element analysis. The concrete medium is modeled as a homogeneous material with smeared properties to investigate and establish the suitable finite element analysis method (explicit versus implicit) and analysis parameters (element size, and solution time increment) also suitable for rigorous investigation. In the next step, finite element analysis model of the medium is developed using a digital image processing technique, which distinguishes the mortar and aggregate phases of concrete. The mortar and aggregate phase topologies are, then, directly mapped to the finite element mesh to form a heterogeneous concrete model. The heterogeneous concrete model is then used to simulate wave propagation. The veracity of the model is demonstrated by evaluating the intrinsic parameters of nondestructive ultrasonic pulse velocity testing of concrete. Quantitative relationships between aggregate size and testing frequency for nondestructive testing are presented.

• 한국도서관정보학회지
• /
• 제54권2호
• /
• pp.1-22
• /
• 2023

본 연구에서는 RDA의 LRM 수용방식을 분석하여 도서관 관련 다양한 표준 및 시스템에서 LRM 적용시 고려사항을 제안하고자 한다. 이를 위해 LRM과 RDA 2020을 개체, 관계, 속성, 인코딩스킴 측면에서 분석하였다. 우선, 개체, 관계, 속성의 매핑을 위해 RDA의 개체별로 속성과 관계를 모두 추출하여, 각 속성과 관계별로 해당하는 LRM 요소를 찾아 매핑하였고, 추가적으로 인코딩스킴도 함께 비교하였다. 결과적으로 LRM을 적용하려는 표준 및 시스템에서 고려할 사항은 첫째, LRM의 계층구조를 고려한 개체 개발, 둘째, 새로운 관계나 지름길 관계 개발, 셋째, 계층구조를 고려하여 개체에 맞는 속성의 세분화, 넷째, 다양한 인코딩스킴의 개발이다. 본 연구는 LRM을 수용하려는 표준이나 시스템에서 자체적인 LRM 적용방안을 모색하는데 활용될 수 있을 것이다.

• 한국컴퓨터정보학회논문지
• /
• 제26권11호
• /
• pp.75-84
• /
• 2021

본 논문에서는 혼합현실에서 다수의 사용자들이 공유객체를 조작하는 과정에서 충돌을 줄이고 충돌로 인한 작업 시간을 줄일 수 있는 적응형 동시성 제어 방법을 제안한다. 혼합현실에서 사용되는 공동 작업에 대해서 세부적인 골들과 이들에 대응되는 태스크들로 분류한 뒤 각 태스크에 알맞은 동시성 제어 방법을 매핑 하여 골-태스크-소유권에 대한 모델링을 수행하고 이에 대한 동시성 제어를 수행한다. 본 논문에서 제안된 시스템은 공동 작업이 진행되어 감에 따라서 같은 태스크이더라도 다른 동시성 제어 방법을 적용하여 사용자들이 동시에 공유 객체들 들고 같이 이동하고 회전을 하는 공동 작업 과정에서 사용자들의 동시적인 작업에 대한 충돌을 제어하여 사용자들에게 현실의 산업 현장과 유사한 혼합협실 공동작업 환경을 제공해 해준다. 본 논문에서 제안한 시스템을 혼합협실 환경에서 실제 동작처럼 작업을 지원하기 위해서 사용자는 MS 홀로렌즈와 마이오 센서를 착용하고 태스크 작업들을 수행한다. 실험 결과 공동 작업 과정에서 충돌 발생과 공동 작업의 완료 시간을 기존의 동시성 제어 방법보다 효과적으로 줄일 수 있었다.

• Genomics & Informatics
• /
• 제12권1호
• /
• pp.35-41
• /
• 2014

Single-nucleotide polymorphisms (SNPs) have been emerging out of the efforts to research human diseases and ethnic disparities. A semantic network is needed for in-depth understanding of the impacts of SNPs, because phenotypes are modulated by complex networks, including biochemical and physiological pathways. We identified ethnicity-specific SNPs by eliminating overlapped SNPs from HapMap samples, and the ethnicity-specific SNPs were mapped to the UCSC RefGene lists. Ethnicity-specific genes were identified as follows: 22 genes in the USA (CEU) individuals, 25 genes in the Japanese (JPT) individuals, and 332 genes in the African (YRI) individuals. To analyze the biologically functional implications for ethnicity-specific SNPs, we focused on constructing a semantic network model. Entities for the network represented by "Gene," "Pathway," "Disease," "Chemical," "Drug," "ClinicalTrials," "SNP," and relationships between entity-entity were obtained through curation. Our semantic modeling for ethnicity-specific SNPs showed interesting results in the three categories, including three diseases ("AIDS-associated nephropathy," "Hypertension," and "Pelvic infection"), one drug ("Methylphenidate"), and five pathways ("Hemostasis," "Systemic lupus erythematosus," "Prostate cancer," "Hepatitis C virus," and "Rheumatoid arthritis"). We found ethnicity-specific genes using the semantic modeling, and the majority of our findings was consistent with the previous studies - that an understanding of genetic variability explained ethnicity-specific disparities.

• BMB Reports
• /
• 제31권4호
• /
• pp.307-327
• /
• 1998

Cytochrome c peroxidase (CcP) is a yeast mitochondrial enzyme which catalyzes the reduction of hydrogen peroxide to water using two equivalents of ferrocytochrome c. The CcP/cytochrome c system has many features which make it a very useful model for detailed investigation of heme protein structure/function relationships including activation of hydrogen peroxide, protein-protein interactions, and long-range electron transfer. Both CcP and cytochrome c are single heme, single subunit proteins of modest size. High-resolution crystallographic structures of both proteins, of one-to-one complexes of the two proteins, and a number of active-site mutants are available. Site-directed mutagenesis studies indicate that the distal histidine in CcP is primarily responsible for rapid utilization of hydrogen peroxide implying significantly different properties of the distal histidine in the peroxidases compared to the globins. CcP and cytochrome c bind to form a dynamic one-to-one complex. The binding is largely electrostatic in nature with a small, unfavorable enthalpy of binding and a large positive entropy change upon complex formation. The cytochrome c-binding site on CcP has been mapped in solution by measuring the binding affinities between cytochrome c and a number of CcP surface mutations. The binding site for cytochrome c in solution is consistent with the crystallographic structure of the one-to-one complex. Evidence for the involvement of a second, low-affinity cytochrome c-binding site on CcP in long-range electron transfer between the two proteins is reviewed.

• Biotechnology and Bioprocess Engineering:BBE
• /
• 제11권2호
• /
• pp.168-172
• /
• 2006

In this study. the transcriptional features of a 2.8 kb region spanning the sigH and rplA genes of Bacillus subtilis were clarified using synthetic oligonucleotides complementary to the transcripts of the rpmG, secE, nusG, and rplK genes. The 5' ends of three transcripts corresponding to this region were located and mapped on the chromosome via primer extension analysis. Three regions, designated Prg, Pn, and Prk, which partially share the consensus sequence recognized by ${\sigma}^A$ RNA polymerase, were theorized to function as promoter elements. The rpmG and secE genes of B. subtilis were cotranscribed from the designated prg promoter, whereas the nusG and rplK genes were transcribed separately from the Pn and Prk promoters, respectively. Accordingly, the transcriptional features, as well as the gene organization, of the region encompassing the sigH and rplA genes of B. subtilis, including the rpmG-secE-nusG-rplK genes, were determined to be distinct from those of Escherichia coli. Divergences in terms of gene organization and transcriptional features within the relevant region would serve as excellent criteria for the delineation of phylogenetic relationships among bacteria.