• The Korean Journal of Cytopathology
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• v.18 no.1
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• pp.1-12
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• 2007

Approximately 70% of cervical cancers are caused by HPV types 16/18 and thus the implementation of vaccination programmes with vaccines against HPV types 16/18 will have a major impact on the incidence of cervical cancer worldwide. However, this reduction will not be seen until several decades after full implementation of such vaccination programmes since the vaccines must be given to young adolescents before exposure to the virus and women who are already sexually active are not likely to be protected. Both GSK and Merck insist that even vaccinated women must continue to participate in regular cervical screening by the most sensitive method available since the vaccine can only give protection against up to 70% of cervical cancers. It is unlikely that the current vaccines will be modified to include additional high risk HPV types in the foreseeable future. While HPV testing is highly sensitive, it is not recommended for women under 30 years of age nor for vaccinated women. Additionally, HPV testing has poor specificity. The Digene Hybrid Capture 2 test is licensed for use only in conjunction with a cytology test, not as a stand-alone test, and the high risk panel has recognised cross reactivity with low risk HPV types. None of the other HPV test methods currently commercially available are FDA approved and all must be internally validated before use. This makes comparison of test results between laboratories difficult. The most sensitive and specific screening test currently available for women of all ages is the Cytyc ThinPrep System consisting of the ThinPrep Pap Test (TPPT) and the ThinPrep Imaging System (Imager). The TPPT was the first LBC system approved by the US FDA in 1996 and there are about 4,000 processors in use worldwide. The Imager was FDA approved in 2003 and over 350 systems are in routine use, mainly in the US. 40% of TPPT in the US are processed on Imager. There is clear evidence in peer reviewed literature that the Imager increases laboratory productivity by 100% and growing evidence that Imager detects more high grade SIL than the conventional smear or manual evaluation of TPPT. This aspect is particularly important since the number of cytological abnormalities will decrease as vaccination programmes are implemented. Cytotechnologists will see fewer and fewer abnormal smears and their skills will be put at risk. By doubling throughput, Imager will allow cytotechnologists to maintain their skills.

• Journal of KIISE:Software and Applications
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• v.32 no.6
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• pp.532-541
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• 2005

We examined the wave pattern of the spleen by using abdominal CT images of a patient with liver cirrhosis, and found that they are different from those of a person with a normal liver. In the abdominal CT image of the patient with liver cirrhosis, there is a deep wave part on the left side of the spleen. In the case of the normal liver, there are waves on the left side, but they aren't deep. Therefore, the total area of waving parts of the spleen with liver cirrhosis is found to be greater than that of the spleen with the normal liver. Moreover, when examining circularity by abstracting the waves of the spleen from the image with liver cirrhosis, we found they are more circular than those of the spleen accompanied by a normal liver. This paper suggests an automatic method to diagnose liver cirrhosis by using the wave pattern of the spleen in abdominal CT images on the basis of the two principles. It tells us that we can judge if the liver has liver cirrhosis automatically, without the manual test of the ratio of caudate lobe to right lobe, only with the spleen.

• Journal of KIISE:Computing Practices and Letters
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• v.12 no.1
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• pp.1-8
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• 2006

Since most CAD tool companies are carrying out very expensive license policies, designers are sharing CAD tools with a limited number of licenses within a design working or research group. It is important to share and use them efficiently, because CAD tool licenses are very valuable resources. Designers should know CAD tool license information such as available number of licenses, types, and configuration methods to use CAD tools properly in their group. Usually, this information is provided by managers who administrate CAD tool license servers in the specific design group. In the previous CAD tool licenses sharing methods, designers have to get CAD tool license information manually and setup the environments with their own hands, If a new designer comes into the design working group, the designer wastes unnecessary time and effort due to these manual processes. As a result, designer's productivity and utilization of CAD tools will decrease. Besides, managers also waste their time and effort, since they should provide CAD tool license information manually to each desiEner. In this paper, we present a more efficient scheme to share CAD tool licenses based on directory service. The proposed method automates not only the communication processes between managers and designers, but also the license configuration steps. We expect this scheme will reduce time and effort of designers and managers as well as enhance the utilization of CAD tools.

• The Journal of Korean society of community based occupational therapy
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• v.3 no.1
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• pp.55-66
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• 2013

Objective : The purpose of present study was to determine effects of task oriented action observation training on dexterity of upper limb function after stroke. Training was progressed to imitation and intensive training after observation to required action in ADL. Method : 15 stroke patients were selected and one group pretest-posttest design was applied. Targets observed performance actions of task orientated task through a video and limitated action repeatedly, Training was performed 3 times a week and 20~30 minutes for each round for 3 weeks. Manual function test and 10-second test and Box and block test were performed for a dexterity of upper extremity motor function, Modified Barthel index and Motor activity log were performed for ADL. Result : After the training, a dexterity of affected upper extremity motor function of the target showed significant difference between before and after intervention, ADL showed significant improvement between before and after intervention. Conclusion : Task orientated Action observation lead a positive effect of recovering a dexterity of upper extremity motor function and ADL. Therefore, this study suggest a action observation training as one strategy of an intervention type of th e occupational therapy.

• Journal of Ecology and Environment
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• v.41 no.12
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• pp.328-335
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• 2017

Background: Some researchers have attempted to evaluate the ecological function of various additional services, away from the main point of view on the timber production of Korean forests. However, basic data, evaluation models, or studies on the absorption of air pollutants related to major plant communities in Korea are very rare. Therefore, we evaluated the functional value of the forest ecosystem in Gongju-city. Plantation manual for air purification, supplied from the Ministry of Environment in Japan, was referred to process and method for assessment of air pollutant absorption. Results: Gross primary production was calculated about average 18.2 t/ha/year. It was a relatively low value in forests mixed with deciduous broad and evergreen coniferous compared to pure coniferous forest. Net primary production was the highest value in deciduous coniferous and was the lowest value in mixed forest with deciduous broad and evergreen broad. And the mean sequestration amount of each air pollutant per unit area per year assessed from gross primary production and concentration of gas was the highest with 75.81 kg/ha/year in $O_3$ and was 16.87 and 6.04 kg/ha/year in $NO_2$ and $SO_2$, respectively. In addition, total amounts of $CO_2$ absorption and $O_2$ production were 716,045 t $CO_2$/year and 520,760 t $O_2$/year in all forest vegetation in Gongju-city. Conclusions: In this study, we evaluated the absorption ability of air pollutant in 2014 on forest in Gongju-city area. Gongju-city has the broad mountain area about 70.3%, and area of deciduous broad leaves forest was established the broadest with 47.4% of genus Quercus. Pg was calculated about average 18.2 t/ha/year. The mean sequestration amount of each air pollutant per unit area per year assessed from Pg and $C_{gas}$ was the highest with 75.81 kg/ha/year in $O_3$ and were 16.87 and 6.04 kg/ha/year in $NO_2$ and $SO_2$, respectively. Absorption rates of $O_3$, $NO_2$, and $SO_2$ were the highest in evergreen coniferous forest about $14.87kgO_3/ha/year$, $3.30kgNO_2/ha/year$, $1.18kgSO_2/ha/year$, and the lowest were $5.95kgO_3/ha/year$, $1.32kgNO_2/ha/year$, and $0.47kgSO_2/ha/year$ in deciduous broad forest. In conclusion, it was evaluated that Japanese model is suitable for estimating air pollutants in Japan to Korean vegetation. However, in Korea, there is a very limited basic data needed to assess the ability of forests to absorption of air pollutants. In this study, the accuracy of a calculated value is not high because the basic data of trees with similar life form are used in evaluation.

• Journal of the Korean GEO-environmental Society
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• v.18 no.11
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• pp.13-18
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• 2017

In a banking process for construction of a complex, non-compaction construction has been applied in most sites, which is a method that soils are compacted by the equipment load without being compacted separately. However, there are no specific descriptions in the construction manual or specifications, so it is unclear to evaluate the excavation volume. Hence, this study is a basic study to compare the soil conversion factor at a design stage and the actual soil conversion factor of a banking ground under a non-compaction condition in order to examine the feasibility in constructing the ground for construction of the complex and to examine appropriateness of the earth work in the site by conducting an indoor, field, and load-settlement test and proposing a reasonable soil conversion factor. Under the non-compaction condition, the soil conversion factor C is set to be 1.0 at the design stage, but the result of the field test was 0.86 which is smaller than the value at the design stage. It was expected that this result would increase the banking volume, and the construction result actually showed a difference in the banking volume. Therefore, for the baking ground under the non-compaction condition, it is necessary to apply the value C suitable for the site condition after performing test by considering the site's condition and the banking height.

• Journal of the korean academy of Pediatric Dentistry
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• v.33 no.1
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• pp.70-76
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• 2006

The aim of this study was comparison of effectiveness of surface treatment methods in reducing the oxygen-inhibited layer of a commercially available freshly polymerized, light cured dental sealant($concise^{TM}$, 3M, St Paul, USA). Surface treatment groups were consisted of no treatment(negative control group) and 3 experimental groups according to surface treatment of light-cured sealant. Experimental group I was 10 seconds' exposure to distilled water syringe, group II was 10 seconds' manual application using a cotton pellet wetted with 75% alcohol and group III was 10 seconds' prophylaxis with pumice/water slurry using rubber cup on a slow-speed handpiece. All specimens were immersed in 5ml distilled water and stored at 37c water bath for 10 minutes. All eluates were analyzed by HLPC for identification and quantitive analysis of monomers. The results of this study can be summarized as follows. 1. None of the chromatograms of the tested sealant displayed peaks with the same retention time as that of the standard solution, except for TEGDMA. 2. All surface treatment group had a statistically significant decrease of monomer release in comparison with no treatment group. 3. Removal effects of unreacted monomer in group III was statistically significant in comparison with group I and group II. These results revealed that mechanical method using pumice and rubber cup is the most effective in removing residual monomer and may be valuable to be used effectively in clinic.

• Journal of Korean Academy of Nursing
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• v.3 no.2
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• pp.111-119
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• 1973

The purpose of this study was to determine whether or not the delivery of health services effects the health knowledge of the recipients of that service. 10 was hypothesized that the practical application of theory, though health services rendered by public health nursing students during their field experiences. would have a positive relationship with the quantity and quality of health knowledge of the female population of a given community. In April 1970, ninety five women(between an age 15-49) from Koyang-Gun were interviewed regarding their knowledge and attitudes in four areas of health: maternal health, child health. family planning and tuberculosis prevention. After 11 years(Nov. l971), during which time the women received home visits by student nurses, the women were again interviewed using the original questionnaire. Additionally, they were asked where they had received information about each question. During the 1$\frac{1}{2}$ year period the visits were made by a total of 112 students. They visited the community twice a week. The result were as follows: Maternal health There was marked improvement in the knowledge of specific aspects of maternal health such as the proper instruments needed for cutting the cord and nutritional precaution of pregnancy (p<0.05). In each case 42.0 percent of more of this knowledge was attributed to information gained from the nursing students. However even after the nursing students'visits, the knowledge of other general areas of maternal remained poor. Child health There were increases in the knowledge of the respondents for the time to supplement breast feeding and for time to wean infants (p<0.05). In each case 35.0 percent or more of this information was attributed to the student. The increase in knowledge regarding types of immunization was more often attributed to the clinic nurse than to the nursing students. Knowledge of the necessity of booster immunization was poor both before and after the visits by the nursing students. Family planing There were significant increases in correct information regarding the time of I.U.D. insertion (P<0.05) and method of taking the oral pill (P<0.05). More than 42.0 percent of the increase was attributed to the nursing students'visits. However there was a slight decrease in correct information about concept of family planning. Tuberculosis There was a general lack of improvement in all areas concerned with tuberculosis. Two thirds of the respondents felt tuberculosis was hereditary and did not know what B.C.G. was. From this study, it could be concluded that in specific area the health knowledge of the female population studied was positively effected by the visits of the nursing students. The study also, suggests, however, that there was a marked unevenness in the overall increase in health knowledge. This raises serious questions which require further research. Suggested areas for further research are (1) Adequacy of the course content preparing nurses for the field experience. (2) A public health nursing manual for student reference. (3) Where and when specific aspects of health can be taught most effectively.

• Journal of the East Asian Society of Dietary Life
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• v.17 no.3
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• pp.393-401
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• 2007

This study was performed to investigate the antioxidant activity of Korean ginseng using an ORAC(Oxygen Radical Absorbance Capacity) assay. Four fractions each (80% ethanol, ethyl acetate, water saturated 1-butanol, and water) were obtained from different ginseng samples (White Ginseng: ; 6 yrs-., 5 yrs-., ; Cork Ginseng: ; 5 yrs-., 4 yrs-.). The saponin content of each fraction was quantified by LC/MS, and the antioxidant capacity of the ginseng was measured by the ORAC assay. The ORAC method, which was recently validated using automatic liquid handling systems, has been adapted for manual handling with the use of a conventional fluorescence microplate reader. Furthermore, the ORAC assay provides a direct measure of hydrophilic chain-breaking antioxidant capacity against peroxy radical, which is the exiting and emission of 2,2'-Azobis (2-methylpropionamidine)-dihychloride (AAPH). As a result of our experiments, ginsenosides Rg1 and Rb1 were the two major saponins found in the ginseng samples, and Rc, Rb2, Re, Rd, Rg3, and Rh1 were detected in a small quantities. For the antioxidant capacities of the fractions (80% ethanol, ethyl acetate, butanol, and water), we found that the organic solvent fraction had similar antioxidant capacities, and were higher than the capacity of the water fraction. When determining the similarities in each fraction, only the ethyl acetate fraction showed similarity compared to other fractions (p>0.05). The antioxidant capacity of ginseng may come from phenolic compounds and some nonpolar saponins. However, based on the results of this study, we hypothesize that some acidic polysaccharides and other biological components may contribute to its antioxidant capacity. Additional research is required to determine other possible biological response modifiers that contribute to the antioxidant capacity of ginseng.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.3
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• pp.45-68
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• 2020

Objectives : This study aims to evaluate the effectiveness and safety of manual and electroacupuncture on glaucoma. Method : We searched 11 electronic databases using index words to identify randomized clinical trials. Meta-analysis of weighted mean difference (WMD) or standardized mean difference (SMD) were used to evaluate the outcomes. Cochrane bias risk assessment tool was used to assess the risk of bias in each clinical study. The collected data was analyzed using RevMan software (ver. 5.3). Results : At the initial stage of data retrieval, 549 papers were searched. After reviewing 37 full texts, a total of 10 RCT studies (426patients, 715 eyes) were selected and 8 RCT studies (357 people, 617 eyes) were involved in meta-analysis. Meta-analysis of 8 RCTs showed that acupuncture alone was more effective in reducing intraocular pressure(IOP) than conventional treatment (WMD = -5.73, 95% CI: [-12.30, 0.83], P = 0.09, I² = 97%) The combination of acupuncture or electroacupuncture with conventional treatment was also effective in lowering IOP (WMD = -1.84, 95% CI: [-2.31, -1.37], P <0.00001, I² = 45%). It was estimated that the combination of acupuncture with conventional treatment was also effective for improving visual field (VF) (WMD = -2.17, 95% CI: [-4.32, -0.02], P = 0.05, I² = 89%) but improvement in visual acuity (VA) was not significant (MD = 0.06, 95% CI: [-0.03, 0.15], P = 0.23, I² = 0%). Subgroup analyzes were performed only for the studies that used open glaucoma as the study's disease and combination of acupuncture or electroacupuncture with conventional therapy would have an effect on lowering intraocular pressure (WMD = -1.68)., 95% CI: [-2.46, -0.90], P <0.0001, I² = 29%). Conclusion : This study suggests that acupuncture treatment for glaucoma may be effective in reducing intraocular pressure and helpful in improving visual field defects. However, due to the small sample size, high risk of bias and high heterogeneity in the methodology, it is expected that further studies will be needed to verify the results. Further studies in large-scale samples based on a minimized biased methodology would be necessary.