• Title/Summary/Keyword: management agent

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Comparison of CT Exposure Dose Prediction Models Using Machine Learning-based Body Measurement Information (머신러닝 기반 신체 계측정보를 이용한 CT 피폭선량 예측모델 비교)

  • Hong, Dong-Hee
    • Journal of radiological science and technology
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    • v.43 no.6
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    • pp.503-509
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    • 2020
  • This study aims to develop a patient-specific radiation exposure dose prediction model based on anthropometric data that can be easily measurable during CT examination, and to be used as basic data for DRL setting and radiation dose management system in the future. In addition, among the machine learning algorithms, the most suitable model for predicting exposure doses is presented. The data used in this study were chest CT scan data, and a data set was constructed based on the data including the patient's anthropometric data. In the pre-processing and sample selection of the data, out of the total number of samples of 250 samples, only chest CT scans were performed without using a contrast agent, and 110 samples including height and weight variables were extracted. Of the 110 samples extracted, 66% was used as a training set, and the remaining 44% were used as a test set for verification. The exposure dose was predicted through random forest, linear regression analysis, and SVM algorithm using Orange version 3.26.0, an open software as a machine learning algorithm. Results Algorithm model prediction accuracy was R^2 0.840 for random forest, R^2 0.969 for linear regression analysis, and R^2 0.189 for SVM. As a result of verifying the prediction rate of the algorithm model, the random forest is the highest with R^2 0.986 of the random forest, R^2 0.973 of the linear regression analysis, and R^2 of 0.204 of the SVM, indicating that the model has the best predictive power.

A New Approach Using the SYBR Green-Based Real-Time PCR Method for Detection of Soft Rot Pectobacterium odoriferum Associated with Kimchi Cabbage

  • Yong Ju, Jin;Dawon, Jo;Soon-Wo, Kwon;Samnyu, Jee;Jeong-Seon, Kim;Jegadeesh, Raman;Soo-Jin, Kim
    • The Plant Pathology Journal
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    • v.38 no.6
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    • pp.656-664
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    • 2022
  • Pectobacterium odoriferum is the primary causative agent in Kimchi cabbage soft-rot diseases. The pathogenic bacteria Pectobacterium genera are responsible for significant yield losses in crops. However, P. odoriferum shares a vast range of hosts with P. carotovorum, P. versatile, and P. brasiliense, and has similar biochemical, phenotypic, and genetic characteristics to these species. Therefore, it is essential to develop a P. odoriferumspecific diagnostic method for soft-rot disease because of the complicated diagnostic process and management as described above. Therefore, in this study, to select P. odoriferum-specific genes, species-specific genes were selected using the data of the P. odoriferum JK2.1 whole genome and similar bacterial species registered with NCBI. Thereafter, the specificity of the selected gene was tested through blast analysis. We identified novel species-specific genes to detect and quantify targeted P. odoriferum and designed specific primer sets targeting HAD family hydrolases. It was confirmed that the selected primer set formed a specific amplicon of 360 bp only in the DNA of P. odoriferum using 29 Pectobacterium species and related species. Furthermore, the population density of P. odoriferum can be estimated without genomic DNA extraction through SYBR Green-based real-time quantitative PCR using a primer set in plants. As a result, the newly developed diagnostic method enables rapid and accurate diagnosis and continuous monitoring of soft-rot disease in Kimchi cabbage without additional procedures from the plant tissue.

Effect of Broccoli Extract on Inhibition of Cancer Cell Proliferation (브로콜리 추출물의 암세포 증식 억제에 미치는 효과)

  • Jeong-Sook Park
    • Journal of Digital Policy
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    • v.2 no.1
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    • pp.31-35
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    • 2023
  • This study was conducted to examine the effect of Broccoli Extract on the proliferation inhibition of human-derived cancer cells and the degree of inhibition. The three cell lines used in the experiment were respiratory system lung cancer cells A549, digestive system liver cancer cells SNU-182 and biliary tract cancer SNU-1196. All cancer cells were derived from the human body, and the CCK-8 method was used to measure the degree of inhibition of cancer cell proliferation. As a result of examining the effect on Broccoli Extract 10ug/mL, 100ug/mL, 1000ug/mL, Broccoli Extract inhibited proliferation in a concentration-dependent manner in most cancer cells, In particular, lung cancer cell A549 and liver cancer cell SNU-182 showed significant proliferation inhibition at 1000ug/mL.As a result, it can be seen that broccoli extract provides potential as a cancer preventive and therapeutic agent for tumor suppression mechanisms proven through cell experiments.

Deep Learning-Based Dynamic Scheduling with Multi-Agents Supporting Scalability in Edge Computing Environments (멀티 에이전트 에지 컴퓨팅 환경에서 확장성을 지원하는 딥러닝 기반 동적 스케줄링)

  • JongBeom Lim
    • KIPS Transactions on Software and Data Engineering
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    • v.12 no.9
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    • pp.399-406
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    • 2023
  • Cloud computing has been evolved to support edge computing architecture that combines fog management layer with edge servers. The main reason why it is received much attention is low communication latency for real-time IoT applications. At the same time, various cloud task scheduling techniques based on artificial intelligence have been proposed. Artificial intelligence-based cloud task scheduling techniques show better performance in comparison to existing methods, but it has relatively high scheduling time. In this paper, we propose a deep learning-based dynamic scheduling with multi-agents supporting scalability in edge computing environments. The proposed method shows low scheduling time than previous artificial intelligence-based scheduling techniques. To show the effectiveness of the proposed method, we compare the performance between previous and proposed methods in a scalable experimental environment. The results show that our method supports real-time IoT applications with low scheduling time, and shows better performance in terms of the number of completed cloud tasks in a scalable experimental environment.

Effect of neem leaves and stock density of earthworm (Eisenia fetida) on quality of rice straw vermicompost

  • Sapna Yadav;Parveen Kumar
    • Advances in environmental research
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    • v.12 no.1
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    • pp.51-64
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    • 2023
  • The sustainable management of rice straw is essential for protection of human health and environment. This study assesses the impact of stock density of earthworm (Eisenia fetida) and Neem leaves (Azadirachta indica) on the quality of the final vermicompost. The vermicompost is produced using different combinations of rice straw, Neem leaves, and cow dung (bulking agent) by varying stock density of earthworms. The vermicomposting experiments are performed in plastic containers (32 cm × 28 cm × 28 cm) in open for 90 days under laboratory conditions. The stock density of the earthworm is found to be an important factor to influence nutritional quality of the final vermicompost. There is observed significant improvement in the total nitrogen (91.8%), phosphate (73.4%), potassium (38.8%), and calcium (59.05%) content of the vermicompost produced with the highest stock density of the earthworms. All the treatments showed decrease in TOC and C:N content after 90 days of vermicomposting. The treatment with Neem leaves showed maximum growth of earthworms (2.65 fold). Neem leaves brought positive changes in the quality of final vermicompost by enhancing the growth and reproduction of the earthworms. The calcium content increased by 39% in the final vermicompost with the addition of Neem leaves at the same stock density of the earthworms. The stock density of the earthworms and Neem leaves are found to significantly improve quality of the final vermicompost as compared with the compost (control). The surface morphology in SEM images showed high degree of fragmentation in the vermicompost as compared with the compost. The combined action of microbes and earthworms resulted in high degree of disintegration in the vermicompost.

Investigating the Cause of Ash Deposition and Equipment Failure in Wood Chip-Fueled Cogeneration Plant (우드칩을 연료로 하는 열병합발전소의 회분 퇴적 및 설비 고장 원인 분석)

  • Min Ji Song;Woo Cheol Kim;Heesan Kim;Jung-Gu Kim;Soo Yeol Lee
    • Corrosion Science and Technology
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    • v.22 no.3
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    • pp.187-192
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    • 2023
  • The use of biomass is increasing as a response to the convention on climate change. In Korea, a method applied to replace fossil fuels is using wood chips in a cogeneration plant. To remove air pollutants generated by burning wood chips, a selective denitrification facility (Selective catalytic reduction, SCR) is installed downstream. However, problems such as ash deposition and descaling of the equipment surface have been reported. The cause is thought to be unreacted ammonia slip caused by ammonia ions injected into the reducing agent and metal corrosion caused by an acidic environment. Element analysis confirmed that ash contained alkali metals and sulfur that could cause catalyst poisoning, leading to an increase in the size of ash particle and deposition. Measurement of the size of ash deposited inside the facility confirmed that the size of ash deposited on the catalyst was approximately three times larger than the size of generally formed ash. Therefore, it was concluded that a reduction in pore area of the catalyst by ash deposition on the surface of the catalyst could lead to a problem of increasing differential pressure in a denitrification facility.

Design of dashboard conceptual model for digital twin based smart pipe health monitoring (디지털 트윈 기반 스마트 파이프 상태 감시를 위한 대시보드 개념모델 설계)

  • Hong, Phil-Doo;Kim, Nam-ho
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.10a
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    • pp.389-391
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    • 2022
  • Efforts by the Ministry of Environment and local governments in Korea are continuing to manage the aging of water supply and sewage buried underground. With the support of the Korea Institute of Environmental Industry and Technology's water and sewage innovation technology development project, it is conducting a project to predict and exchange accidents due to aging, and to apply smart functions to new buried pipes. As one of these studies, this paper proposes the design of a dashboard concept model for digital twin-based smart pipe health monitoring, one of the key features of the entire study. Since remote control and monitoring are one of the main functions, distributed transmission and reception agents are deployed to visualize monitoring situations in real time and to increase user affinity by deploying intuitive UI. To validate the design of this proposed special digital twin based smart pipe state monitoring, we construct the conceptual model level and measure the agent effectiveness to validate its excellence.

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Pain Relief Efficacy of Ibuprofen Releasing Foam Dressing (Biatain Ibu®) on Outpatient Patient with Partial Thickness Burn Wound (부분층화상을 입은 외래 환자에서 이부프로펜 방출성 드레싱 제재(Biatain Ibu®)의 창상부위 통증의 경감 효과에 대한 연구)

  • Lee, Jun-Ho;Choi, Bong Gyu;Lee, Jin Ho;Kim, Jae Won
    • Journal of the Korean Burn Society
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    • v.22 no.1
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    • pp.15-19
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    • 2019
  • Purpose: Pain management in burn treatment is important in improving wound healing and quality of life. Ibuprofen is a proven pain relieving agent in patients with partial thickness burn by intraveous injection. The purpose of this study is to evaluate the efficacy of Biatain Ibu® (polyurethane foam containing ibuprofen) in pain control for outpatients with partial thickness burns. Methods: A prospective randomized clinical trial was performed in outpatients with partial thickness burn from August 1, 2017 to July 31, 2018. Acute pain, chronic pain, complications, days for re-epithelialization and patient's satisfaction were compared between Biatain Ibu® and Biatain® groups. Results: A total of 20 patients (Biatain Ibu®, n=10; Biatain®, n=10) were assessed in the trial. On Burn days 3, 5, 7, 11, 13, and 15, the acute pain levels were significantly lower in the Biatain Ibu® group than in the Biatain® group. Complications, chronic pain levels and days for re-epithelialization were not significantly different between the two groups. Patient's satisfaction was not statistically significant but was higher in the Biatain Ibu® group. Conclusion: Biatain Ibu® is effective in relieving pain in outpatients with partial thickness burn without decreasing patient satisfaction, wound healing ability or developing any complications.

Biological Control of Fusarium oxysporum, the Causal Agent of Fusarium Basal Rot in Onion by Bacillus spp.

  • Jong-Hwan Shin;Ha-Kyoung Lee;Seong-Chan Lee;You-Kyoung Han
    • The Plant Pathology Journal
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    • v.39 no.6
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    • pp.600-613
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    • 2023
  • Fusarium oxysporum is the main pathogen causing Fusarium basal rot in onion (Allium cepa L.), which incurs significant yield losses before and after harvest. Among management strategies, biological control is an environmentally safe and sustainable alternative to chemical control. In this study, we isolated and screened bacteria for antifungal activity against the basal rot pathogen F. oxysporum. Isolates 23-045, 23-046, 23-052, 23-055, and 23-056 significantly inhibited F. oxysporum mycelial growth and conidial germination. Isolates 23-045, 23-046, 23-052, and 23-056 suppressed the development of Fusarium basal rot in both onion seedlings and bulbs in pot and spray inoculation assays. Isolate 23-055 was effective in onion seedlings but exhibited weak inhibitory effect on onion bulbs. Based on analyses of the 16S rRNA and rpoB gene sequences together with morphological analysis, isolates 23-045, 23-046, 23-052, and 23-055 were identified as Bacillus thuringiensis, and isolate 23-056 as Bacillus toyonensis. All five bacterial isolates exhibited cellulolytic, proteolytic, and phosphate-solubilizing activity, which may contribute to their antagonistic activity against onion basal rot disease. Taken together B. thuringiensis 23-045, 23-046, 23-052, and 23-055 and B. toyonensis 23-056 have potential for the biological control of Fusarium basal rot in onion.

Botrytis cinerea hypovirulent strain △BcSpd1 induced Panax ginseng defense

  • Shuhan Zhang;Junyou Han;Ning Liu;Jingyuan Sun;Huchen Chen;Jinglin Xia;Huiyan Ju;Shouan Liu
    • Journal of Ginseng Research
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    • v.47 no.6
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    • pp.773-783
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    • 2023
  • Background: Gray mold, caused by Botrytis cinerea, is one of the major fungal diseases in agriculture. Biological methods are preferred over chemical fungicides to control gray mold since they are less toxic to the environment and could induce the resistance to pathogens in plants. In this work, we try to understand if ginseng defense to B. cinerea could be induced by fungal hypovirulent strain △BcSpd1. BcSpd1 encodes Zn(II)2Cys6 transcription factor which regulates fungal pathogenicity and we recently reported △BcSpd1 mutants reduced fungal virulence. Methods: We performed transcriptomic analysis of the host to investigate the induced defense response of ginseng treated by B. cinerea △BcSpd1. The metabolites in ginseng flavonoids pathway were determined by UPLC-ESI-MS/MS and the antifungal activates were then performed. Results: We found that △BcSpd1 enhanced the ginseng defense response when applied to healthy ginseng leaves and further changed the metabolism of flavonoids. Compared with untreated plants, the application of △BcSpd1 on ginseng leaves significantly increased the accumulation of p-coumaric acid and myricetin, which could inhibit the fungal growth. Conclusion: B. cinerea △BcSpd1 could effectively induce the medicinal plant defense and is referred to as the biological control agent in ginseng disease management.