• Title/Summary/Keyword: malignant

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Reconstruction of Thoracic Wall Defect in Tumors of Chest Wall -Report of Four Cases- (흉벽에 발생한 종양 -흉벽 재건술 4례-)

  • 이선희;김세화;이홍균
    • Journal of Chest Surgery
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    • v.8 no.1
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    • pp.29-36
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    • 1975
  • We have experienced 49 cases of tumors of chest wall at St. Mary`s Hospital from Jan. 1963 to Dec.1974. In four cases of them, the reconstruction of chest wall defects performed. 1] Out of 49 cases of tumors of the chest wall, 27 cases were benign tumors, 14 cases metastatic malignant tumors, and 8 cases primary malignant tumors. 2] Twenty-six cases [50%] of tumors of the chest wall were on the bony cage. Among them benign tumors were 9 cases [35%], metastatic malignant tumors 14 cases [53%], and primary malignant tumors 3 cases [12%]. Of these, 24 cases were located on the ribs and 2 cases on the sternum.3] The malignant tumors of bony chest wall were excised in en bloc resection including involved ribs. The wide defects of bony chest wall were reconstructed by means of displacement of neighboring ribs and mobilized diaphragm, in the two osteogenic sarcomas of rib, and of prosthesis with silastic sheets in one rhabdomyosarcoma and one metastatic adenocarcinoma of lung.

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Synchronous Presentation of Papillary Thyroid Cancer and Malignant Lymphoma (경부 악성 림프종과 동반된 유두상 갑상선암)

  • Chang Hang-Seok;Chung Woong-Youn;Park Cheong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.14 no.2
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    • pp.253-259
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    • 1998
  • The increasing risk of subsequent malignancy after treatment of malignant lymphoma is well known, which is mainly due to longer survival of these patients. Radiotherapy at an early stage of Hodgkin's disease or non-Hodgkin's lymphoma is accepted to be associated with future occurrence of secondary thyroid cancer. Nevertheless, the synchronous presentation of these malignancies is extremely rare. Well differentiated thyroid cancer, a slow-growing tumor that responds to therapy with surgery and radioactive iodine, is associated with prolonged survival. therefore, it is important to make this diagnosis in patients who show evidence of malignant lymphoma. Furthermore, appropriate treatment must be considered for thyroid cancer to improve the prognosis of these patients. We herein reported 4 cases of synchronous thyroid cancer and malignant lymphoma in patients who had not previously recieved radiotherapy or chemotherapy.

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MAXILLOFACIAL INFECTIONS MASQUERADING AS MALIGNANT TUMOR ; CASE REPORTS (악성종양과 감별이 어려웠던 악안면 영역의 감염질환에 대한 치험례)

  • Seo, Jae-Hoon;Yeo, Hwan-Ho;Kim, Young-Kyun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.17 no.3
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    • pp.302-308
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    • 1995
  • It is very difficult to differentiate the malignant tumor from the maxillofacial infections that have unclear cause, severe indurated swelling, pain and nonresponsiveness to antibioitic treatment and incision and drainage. Incisional biopsy, CT, and MRI examination may not distinguish between infection and a malignant tumors. And then, the clinicians can make a mistake that they perform a unnecessary radical surgery because of inaccurate diagnosis. We present three case reports of maxillofacial infectious disease with diagnosis process, treatment and differential diagnosis. The infectious disease were not resolved with antibiotic and surgical drainage. The progression of clinical sign and radiographic, indings of these disease were masqueraded as malignant tumors.

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Fine Needle Aspiration Cytology of Malignant Epithelial Mesothelioma of the Peritoneum (복강에 발생한 악성 상피성 중피종의 세침흡인생검)

  • Sung, Sun-Hee;Lee, Kwang-Gil
    • The Korean Journal of Cytopathology
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    • v.2 no.1
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    • pp.43-50
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    • 1991
  • A case of malignant epithelial mesothelioma of the peritoneum diagnosed by fine needle aspiration cytology is described. The smear showed many Individually scattered or clustered large round malignant epithelial cells intermingled with relatively small nonneoplastic mesothelial and mesenchymal cells. Papillary configurations with thick fibrous core were also seen. The malignant cells were virtually reminiscent of reactive mesothelial cells but they were larger in size and had more prominent nucleoli and more frequent binucleated or multinucleated cell formations than reactive mesothelial cells. The characteristic features of malignant cell of mesothelioma compared with the metastatic adenocarcinoma were relatively uniform cellular size, prominent round nucleoli, large round vesicular nuclei with finely granular chromatin pattern, smooth nuclear membrane, abundant glassy cytoplasm rather than bubbly mucin-containing cytoplasm and fuzzy cell border.

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Malignant Transformation of Craniopharyngioma without Radiation Therapy: Case Report and Review of the Literature

  • Jeong, Tae Seok;Yee, Gi Taek;Kim, Na Rae
    • Journal of Korean Neurosurgical Society
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    • v.60 no.1
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    • pp.108-113
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    • 2017
  • Craniopharyngiomas exhibiting histologic malignancy are extremely rare. Herein, we report the case of a 26-year-old male patient who underwent suprasellar mass excision via an interhemispheric transcallosal approach. Histopathological examination indicated that the craniopharyngioma was of the adamantinomatous subtype. The patient received postoperative medical treatment for endocrine dysfunction and diabetes mellitus without radiation treatment. Two years after the operation, he presented with progressive visual disturbance and altered mentality. Magnetic resonance imaging revealed a huge mass in the suprasellar cistern and third ventricle. He underwent a second operation via the same approach. The histopathological examination showed an adamantinomatous craniopharyngioma with sheets of solid proliferation in a spindled pattern, indicating malignant transformation. Malignant transformation of craniopharyngioma in the absence of radiation therapy has been reported in only five cases, including this one. We present a case of malignant transformation of craniopharyngioma with a brief review of relevant literature.

Malignant Anal Sac Melanoma in a Dog

  • Ahn, Soo-Min;Cho, Kyoung-Oh;Kim, Sang-Ki;Jung, Dong-In;Yu, DoHyeon
    • Journal of Veterinary Clinics
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    • v.36 no.6
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    • pp.349-352
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    • 2019
  • A five-year-old female Yorkshire Terrier dog presented with a perianal mass. Fine needle aspiration revealed that the mass comprised two different types of cells: hepatoid epithelial cells and melanin-containing melanocytes. Histopathological examination confirmed perianal gland adenoma with malignant melanoma. Evidence of metastasis was found on thoracic radiography with soft-tissue densities observed within the pulmonary parenchyma. The dog survived for three months after diagnosis of malignant melanoma. This report describes the clinical findings, diagnostics used, cytological and histopathological findings, and the potential prognosis for a dog diagnosed with malignant anal sac melanoma.

Pancreatic metastasis from malignant phyllodes tumor of the breast

  • Lee, Seung Eun;Bae, Young Kyung;Choi, Joon Hyuk
    • Journal of Yeungnam Medical Science
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    • v.38 no.1
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    • pp.78-82
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    • 2021
  • Pancreatic metastasis from malignant phyllodes tumor (PT) of the breast is rare, and only a few cases have been reported in the literature. Here, we report a case of pancreatic metastasis from malignant PT of the breast in a 48-year-old woman. She had had three episodes of recurrence of malignant PT in her right breast. She presented with epigastric pain for 2 months. Computed tomography and magnetic resonance imaging revealed a 6 cm-sized, well-defined, heterogeneous mass with peripheral enhancement in the body of the pancreas. Endoscopic ultrasonography-guided fine-needle aspiration was performed, and the pathologic report suggested spindle cell mesenchymal neoplasm. Subsequently, surgical excision was performed, and the mass was confirmed as a metastatic malignant PT. The imaging findings are discussed and the literature is briefly reviewed in this report.

Two Cases of Malignant Myoepithelioma in Parotid Gland (이하선에 발생한 악성 근상피종 2예)

  • Kim Seok-Beom;Yang Young-June;Hwang Jung-Ho;Baek Seung-Kuk;Kim Yong-Bok
    • Korean Journal of Head & Neck Oncology
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    • v.18 no.2
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    • pp.211-215
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    • 2002
  • A myoepithelial carcinoma, a rare malignant salivary gland neoplasm, occurs mostly in the parotid gland. The incidence of myoepithelioma is less than 1% of all salivary gland tumors, and malignant myoepithelioma is even more rare. Biological behavior of myoepithelial carcinoma has not been fully clarified. Malignant myoepithelioma shows clinicopathologic diversity and presents with various stages of myoepithelial differentiation. The definite treatment for malignant myoepithelioma is surgical excision, and the role of radiation therapy and chemotherapy is not yet established. In this study, we have experienced two patients with malignant myoepithelioma of the parotid gland who were treated with surgical excision.

Malignant Lymphoma of the Larynx (후두악성임파종)

  • Cho Jung-Il;Kim Kwang-Moon;Kim Young-Ho;Choi Jae-Jin
    • Korean Journal of Head & Neck Oncology
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    • v.11 no.2
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    • pp.137-144
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    • 1995
  • Malignant lymphoma affecting the larynx is uncommon, probably accounts for less than 1 percent of malignant lesion of the larynx. Malignant lymphoma of the larynx is predominantly localized to supraglottis such as epiglottis, aryepiglottic fold. Laryngoscopy reveals a irregular submucosal mass with a smooth surface and no ulceration. Most of which belongs to non­Hodgkin's lymphoma. After it has been determined that the disease is localized, radiation therapy is the choice of the treatment. Chemotherapy with or without irradiation is reserved for more advanced tumor. Then life-long follow-up is essential. This paper deals with 5 cases malignant lymphoma of the larynx to review our clinical experience and to suggest the optimum treatment in the course of the disease.

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A Large Malignant Peripheral Nerve Sheath Tumor in the Neurofibromatosis Patient: A Case Report (신경섬유종증 환자에 발생한 거대 악성말초신경초종의 치험례)

  • Choi, Dong Il;Seo, Dong Kuk;Jo, Woo Sung;Chung, Chul Hoon;Cho, Seong Jin
    • Archives of Plastic Surgery
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    • v.33 no.6
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    • pp.761-763
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    • 2006
  • Purpose: Malignant peripheral nerve sheath tumors most often arise from the anatomically discernible peripheral nerve or neurofibroma. Methods: A 55-year-old man had a rapidly growing pedunculated large mass on the sacrolumbar junction for 2 years. He has congenital neurofibromatosis type I. He had multiple caf-au-lait spots and multiple neurofibromas on the entire body. The mass developed from a subcutaneous nodule on the sacrolumbar junction and grew rapidly. The preoperative punch biopsy revealed a malignant peripheral nerve tumor. The mass was completely excised with 1 cm free margin above the deep fascial plane. Results: There was no evidence of recurrence of tumor for 19 months of follow-up examination. Conclusion: Malignant peripheral nerve sheath tumor is very rare and has unique feature. We report a successful case of malignant peripheral nerve sheath tumor with the review of the literatures.