Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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Two Cases of Malignant Myoepithelioma in Parotid Gland

이하선에 발생한 악성 근상피종 2예

  • Kim Seok-Beom (Department of Otolaryngology-Head & Neck Surgery, Hallym University College of Medicine) ;
  • Yang Young-June (Department of Otolaryngology-Head & Neck Surgery, Hallym University College of Medicine) ;
  • Hwang Jung-Ho (Department of Otolaryngology-Head & Neck Surgery, Hallym University College of Medicine) ;
  • Baek Seung-Kuk (Department of Otolaryngology-Head & Neck Surgery, Hallym University College of Medicine) ;
  • Kim Yong-Bok (Department of Otolaryngology-Head & Neck Surgery, Hallym University College of Medicine)
  • 김석범 (한림대학교 의과대학 이비인후-두경부외과학교실) ;
  • 양영준 (한림대학교 의과대학 이비인후-두경부외과학교실) ;
  • 황정호 (한림대학교 의과대학 이비인후-두경부외과학교실) ;
  • 백승국 (한림대학교 의과대학 이비인후-두경부외과학교실) ;
  • 김용복 (한림대학교 의과대학 이비인후-두경부외과학교실)
  • Published : 2002.11.01
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Abstract

A myoepithelial carcinoma, a rare malignant salivary gland neoplasm, occurs mostly in the parotid gland. The incidence of myoepithelioma is less than 1% of all salivary gland tumors, and malignant myoepithelioma is even more rare. Biological behavior of myoepithelial carcinoma has not been fully clarified. Malignant myoepithelioma shows clinicopathologic diversity and presents with various stages of myoepithelial differentiation. The definite treatment for malignant myoepithelioma is surgical excision, and the role of radiation therapy and chemotherapy is not yet established. In this study, we have experienced two patients with malignant myoepithelioma of the parotid gland who were treated with surgical excision.

Keywords

References

  1. Sciubba JJ, Brannon RB : Myoepitheloma of salivary glands. Cancer. 1982 ; 49 : 562-572 https://doi.org/10.1002/1097-0142(19820201)49:3<562::AID-CNCR2820490328>3.0.CO;2-6
  2. Tavassoli FA : Myoepithelial lesions of the breast. Am J Surg PathoI. 1991 ; 15 : 554-568 https://doi.org/10.1097/00000478-199106000-00004
  3. Heathcote JG, Hurwitz JJ, Dardick I : A spindle-cell myoepithelioma of the lacrimal gland. Arch Ophthalmol. 1990 ; 108 : 1135-1139 https://doi.org/10.1001/archopht.1990.01070100091041
  4. Di Palma S, Guzzo M : Malignant myoepithelioma of salivaryglands : Clinicopathological features often cases. Virchows Arch A Pathol Anat Histopathol. 1993 ; 423:389-396 https://doi.org/10.1007/BF01607152
  5. Toshitaka N, Isamu S, Yasuo T, Osamu M, Akiyoshi K : Salivary gland malignant myoepithelioma : A clinicopathologic and immunohistochemical study of ten cases. Cancer. 1998 ; 83 : 1292-1299 https://doi.org/10.1002/(SICI)1097-0142(19981001)83:7<1292::AID-CNCR4>3.0.CO;2-L
  6. Bong JP, Park JH, Choi HM, et at : A case of malignant myoepithelioma in parotid gland. Korea J Otolaryngol. 2002 ; 45 : 624-627
  7. Dardick I, Thomas MJ, Peter AW : Myoepithelioma-New concepts of history and classification : A light and electron microscopic study. Ultrastructural Pathol. 1989 ; 13 : 187-224 https://doi.org/10.3109/01913128909057442
  8. John GB : Pathology consultation : Myoepithelioma. Ann Otol Rhinol Laryngol. 1985 ; 94 : 523-524 https://doi.org/10.1177/000348948509400523
  9. Sheldon WH : So-called mixed tumors of the salivary glands. Arch PathoI. 1943 ; 35 : 1-20
  10. Lee GH, Park CG, Lee YS, Oh KK, Shim YS : Minor salivary gland tumors : A clinical study of 83 cases. Korean J Otolaryngol. 1995 ; 38 : 752-762
  11. Kang SH, Kim SW, Kang JM, Kim KI : Myoepithelioma of Salivary gland: Report of 2 cases. Korean J Otolaryngol. 1998 ; 41 : 113-116
  12. Savera AT, Sloman A, Huvos AG, Klimastra DS : Myoepitherial carcinoma of the saliary glands : A clinicopathologic study of 25 patients. Am J Surg Pathol. 2000 ; 24 : 762-774
  13. Mccluggage WG, Primrose WJ, Toner PG : Myoepitherial carcinoma (malignant myoepitherioma) of the parotid gland arising in a pleomorphic adenoma. J Clin Pathol. 1998 ; 51 : 552-556 https://doi.org/10.1136/jcp.51.7.552
  14. Redmann RS : Myoepithelium in salivary glands. Microscopic Research and Technique. 1994 ; 27 : 25-45 https://doi.org/10.1002/jemt.1070270103