• Title/Summary/Keyword: male hair loss

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Case of improvement of hair loss using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 탈모 개선 사례)

  • Yeon Choi
    • CELLMED
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    • v.14 no.3
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    • pp.70.1-70.3
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    • 2024
  • Objective: Report of a case of improvement of hair loss through the use of OCNT. Methods: A 60-year old Korean male has been suffering from hair loss. Results: Hair loss was markedly improved following implementation of OCNT. Conclusion: Application of OCNT to hair loss can be helpful in alleviation of the symptoms.

The Clinical Study Using Oriental Medicine Extract on Male Pattern Hair Loss

  • Lee Yoon-Gyeong;Kim Jeong-Ki;Cho Hyun Gug
    • Biomedical Science Letters
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    • v.10 no.3
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    • pp.317-324
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    • 2004
  • In order to examine the clinical effects on male pattern hair loss, the oriental medicine extract composed of Polygoni multiflori Radix, Angelica gigantis Radix and Lycii Fructus was tested to balding people. 40 males and 10 females were participated in this experiment, and they had spread the extract on their scalp themselves one time a day for 18 months. After 18 months, all participants submitted the reports that had questionnaires to determine the effect of topical oriental medicine extract on hair growth and/or hair loss preventing in balding people. In the results, ir was found that hair density on the entire scalp was gradually increased during the spreading period of the extract in most of balding people. The hair loss was observed about 1 week or 2 months after extract treatment and hair growth was observed about 6 months after extract treatment. In the reports, 74% of participants answered that the extract was effective on hair growth and hair loss preventing, and improvement of scalp condition. From these results, it is suggested that the extract composed of Polygoni multiflori Radix, Angelica gigantis Radix and Lycii Fructus may be an effective medical care to hair growth and hair loss preventing in human.

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A Case Study on the Improvement of Hair Loss Using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 탈모 개선 사례 연구)

  • Ki-won Kim
    • CELLMED
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    • v.13 no.5
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    • pp.19.1-19.3
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    • 2023
  • Objective: A case report on the improvement of bald crown by Ortho-Cellular Nutrition Therapy (OCNT). Methods: A 61-year-old Korean male suffering from bald crown, male pattern baldness, and reduced hair thickness Results: Bald crown improved after Ortho-Cellular Nutrition Therapy (OCNT). Conclusion: Ortho-Cellular Nutrition Therapy (OCNT) is effective in relieving the symptoms of hair loss patients.

A Case Study on the Improvement in Hypertension and Hair Loss Patient Using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 고혈압 및 탈모 개선 사례 연구)

  • Hochin Kim
    • CELLMED
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    • v.14 no.5
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    • pp.75.1-75.3
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    • 2024
  • Objective: A case study on alleviating hypertension-related symptoms and hair loss through Ortho-Cellular Nutrition Therapy (OCNT). Methods: A 58-year-old male patient, suffering from hypertension and hair loss, was treated with OCNT. Results: After applying OCNT, a reduction in blood pressure and improved hair loss symptoms were observed. Conclusion: The application of OCNT can be beneficial in mitigating hypertension and hair loss.

A survey of the status of hair loss product use, hair loss treatment and satisfaction level (탈모(脫毛) 고객(顧客)의 제품이용실태와(製品使用實態) 관리(管理) 및 만족도(滿足度) 조사(調査))

  • Lee, Ji-Suk;Kim, Sung-Nam
    • Journal of Fashion Business
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    • v.11 no.2
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    • pp.76-91
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    • 2007
  • The domestic market for scalp care and hair loss management reached 1 trillion won. The market for hair loss management is expected to expand further. Systematic scalp and hair care services, such as scalp scaling, scalp massage, equipment maintenance, scalp care products sale, and care program based on scalp and trichology are provided. This study examined the status of hair loss management and use of hair care products by people experiencing hair loss and the level of their satisfaction. In addition, this study presents basic data for the effective hair loss management and marketing strategies for scalp and hair loss clinics. The results are as follows. 41.2% of the study subjects were in their 20s, and 66.6% of the study subjects were women. As for the hair loss symptoms, 45.2%, the largest percentage, had thin and wispy hair and more women had thin hair than men. 80.0% of men had oily hair. As for the scalp condition, 39,3% had oily scalp. As more women experience hair loss, 39.6% had female pattern hair loss and 31.0% had male pattern hair loss. As the largest percentage of people experiencing hair loss was in their 20s, 33.4%, the largest percentage, had the onset of hair loss in their early 20s. 34.1%, the largest percentage, reported having used the clinic for less than 1 month. The older the subject, the longer the length of hair clinic use. As for the average number of monthly hair loss clinic visits, 28.2%, the largest percentage, said 3 times. As for the hair loss management product use, 61.9%, said they do not use it and 38.1% said they use it. 5.6%, the largest percentage, used Davines at home and 9.6%, the largest percentage, used Kerastase at the clinic. As for the experience of hair loss product previously, 84.5% said they had no experience and 15.5% said they had eThe following are related to the satisfaction level of hair loss management. xperience. 5.0%, the largest percentage, reported having used Daenggimeori. The following are related to the satisfaction level of hair loss management. 32.8%, the largest percentage, said the effect of hair loss management lasted less than 6 monthas. As for the satisfaction levels on hair loss management program, service, skill of the hair specialist, hygiene, and hair loss management products, most people indicated between average and somewhat satisfactory levels. As for the satisfaction level on the cost of hair loss management, most people indicated average satisfaction level. As for the element essential to hair loss management, 39.0%, the largest percentage, indicated development of effective and specialized programs, 28.2%, indicated low price, 25.1%, indicated systematic and professional education of the hair specialist, 4.6%, indicated marketing and promotion, 2.5%, indicated service quality, and 0.6% indicated others.

In vivo and In vitro hair growth promotion effects of extract from Glycine soja Siebold et Zucc

  • Yang, Jae Chan;Kim, Bo Ae
    • Journal of Applied Biological Chemistry
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    • v.59 no.2
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    • pp.137-143
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    • 2016
  • Hair is a dermal adjunctive organ that protects the body from external physical and chemical stimuli; hair undergoes anagen, catagen, and telogen phases, with hair-loss occurring during the telogen phase. Alopecia is a condition wherein a person undergoes hair-loss far exceeding the normal amount, owing to diverse external factors. Wild beans are rich in isoflavone and amino acids known to prevent hair-loss; compared to cultivated beans, many wild bean species have higher protein content. This study aimed to develop a hair growth promoting solution, with superior hair growth promoting effects and fewer side effects, using naturally obtained Glycine soja Siebold et Zucc (GSSZ) extracts. Seven-week-old C57BL/6N male mice were classified into different experimental groups. Hair growth was observed in GSSZ-treated mice, and compared against that seen in 3 % minoxidil (MXD, positive control)-treated mice. Visual observations revealed a greater reduction in hair-loss in MXD and GSSZ application groups, compared to that in TXN group (hair loss induction using 1 % testosterone). Evaluation using an image analysis software revealed that compared to the positive control, TXN + GSSZ group showed the highest hair growth. TXN + MXD and control groups exhibited similar follicular cell growth, while the hair growth promotion patterns were similar in the negative control (normal), TXN + GSSZ, and TXN groups, as observed via histological analysis. GSSZ did not induce cytotoxicity (even at 2 mg/mL) in keratinocytes and dermal papilla cells; alternately, dermal papilla cell proliferation was activated in a (GSSZ) concentration-dependent manner. Therefore, the GSSZ extract promoted hair growth and increased hair growth-related cell activity, and could therefore be utilized in alopecia treatment.

Investigation of Antioxidant Activity of Cynanchi Wilfordii Radix and Inhibitory Effect of 5α-reductase mRNA in Human Dermal Papilla Cells (백수오(白首烏)의 항산화 효능 및 모유두 세포의 5α-reductase mRNA 발현 억제 효능)

  • Cho, Nam Joon;Choi, Young Ho;Jeon, Hai Li;Lee, Woong Hee;Kim, Kee Kwang;Han, Hyo Sang
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.31 no.6
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    • pp.374-379
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    • 2017
  • Hair loss affects interpersonal relationships and causes psychological stress. In this study, we investigated the antioxidant activity of Cynanchi Wilfordii Radix (CWR) and its effects on dermal papilla (DP) cells. Antioxidant efficacy was examined by ABTS assay. To confirm the effect on cell activity, MTS assay was performed and cell count was directly measured by hemocytometer. The mRNA expression of genes involved in hair formation and hair loss formation was confirmed by quantitative RT-PCR. CWR has a strong antioxidant activity. Cell viability of DP cells was increased to 118.5% by treatment of 0.5 mg/ml CWR for 24 hours, but the effect on the cell number was insignificant. These results suggest that CWR increases mitochondrial activity without promoting cell proliferation. Treatment of DP cells with 0.5 mg/ml CWR resulted in 48.5% reduction of mRNA expression of type 2 $5{\alpha}$-reductase, a major cause of male hair loss. In addition, mRNA expression of bone morphogenetic pretein (BMP), fibroblast growth factor (FGF)7, and FGF10, which are closely related to hair growth, was also decreased. Reactive oxygen species (ROS) acts as a cause of hair loss. The excellent antioxidant efficacy of CWR is thought to be able to effectively remove ROS. The dihydrotestosterone produced by type 2 $5{\alpha}$-reductase in DP cells is a potent inducer of male pattern hair loss. The inhibitory effect of type 2 $5{\alpha}$-reductase mRNA on DP cells induced by CWR may induce a positive therapeutic effect of male pattern hair loss.

The Preclinical and Clinical Effects of Herbal Product Containing Rosa mutiflora Roots Extracts as a Main Component on the Hair Growth Promotion (찔레뿌리 추출물을 주성분으로 하는 천연물 조성물의 발모촉진 효과에 관한 전임상 및 임상시험 연구)

  • Kim, Joong-Hark;Hong, Sung-Kil;Hwang, Sung-Jue;Son, Sang-Wook;Choi, Yong-Soon
    • Korean Journal of Medicinal Crop Science
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    • v.20 no.2
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    • pp.108-116
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    • 2012
  • In this study, to develop hair growth agents using natural products which has excellent ability to promote hair growth effect and fewer side effect, animal experiment and clinical trials was performed to evaluate hair growth promotion effect of herbal product containing $Rosa$ $mutiflora$ roots extracts as a main component (RMHP). 4-week-old male C57BL/6 mice were removed the dorsal hair using thioglycolate, and applied 15% EtOH solution as a negative control, 5% minoxidil as a positive control and RMHP to dorsal skin. In the results of macroscopy and photo-interpretation, RMHP group recorded 100% (+++++) of hair growth was proved to significantly stimulate hair growth against 80% (++++) negative control group. 37 patients were treated with RMHP and evaluated the therapeutic effect at 16 weeks. Hair density was significantly increased at 16 weeks after applying RMHP ($125.0{\pm}4.9\;FU/cm^2$) compared to before treatment ($104.3{\pm}4.7\;FU/cm^2$, p < 0.05), and hair thickness were also significantly increased ($0.066{\pm}0.003$ mm) than before treatment ($0.055{\pm}0.002$ mm, p < 0.05). The result of clinical photo-interpretation using 7-point rating scale assessment, after 16 weeks clinical symptoms were evaluated to significantly improve with $1.23{\pm}0.05$ (p < 0.05). Therefore, the results of this study were observed that RMHP have hair loss prevention effect and hair growth promotion effect to hair loss patients.

Effectss of Biotin-rich Functional Food (Whalgichan) on Hair Growth and Biological Stimulation in Rat and Human

  • Chung, Cha-Kwon
    • Preventive Nutrition and Food Science
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    • v.5 no.1
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    • pp.42-47
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    • 2000
  • For the development of functional food for hair-growth stimulation, this study has tried an in vivo and clinical test. As an in vivo test male Sprague Dawley rats and as a clinical test 27 baldheaded or loosehaired men were recruited. Before the experiment, the total hair count in 6 $\textrm{mm}^2$ of the designated area was 46.5. In four weeks and eight weeks of the functional food feeding it increased to 61.8 and 75.3, respectively. Hence the net increase was totaled at 62% in eight weeks. Also, depilation was decreased by 28%. Before the experiment, average hair loss was 65.7. In four weeks and eight weeks of the functional food feeding it decreased to 55.2 and 47.3, respectively. LDL and phospholipids were decreased by 42% and 36%, respectively during that period. However, HDL was increased by 21%. Forty percent of the subjects responded that itching of head skin was reduced and 34% responded to have reduced dandruff. No side-effects among the subjects were examined and no other blood pa-rameters were significantly affected by the diet. The results in this study suggest that biotin-rich functional food may stimulate cholesterol and lipid metabolism and blood flow leading to the growth of new hair and prevention of hair loss.

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Oriental Medicine Therapy in the Treatment of Men with Androgenetic Alopecia (남성의 안드로겐성 탈모증에 대한 한의학적 치료 효과)

  • Yi, Tae-Hoo;Moon, Jung-Bae;Kim, Young-Jin;An, Kyung-Eh
    • Journal of Acupuncture Research
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    • v.23 no.1
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    • pp.179-186
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    • 2006
  • Background : Recently the demand was increasing on the data describing treatment rates and the outcome of Androgenetic Alopecia using Oriental Medicine. Thus this study was designed to observe androgenetic Alopecia treatment using Oriental Medicine including acupuncture and herb because there has been no such statistics. Objectives : Our purpose was determine whether oriental medicine treatment leads to clinical improvement in men with androgenetic alopecia. Methods : Eighty two Men, 17 to 53 years of age, with male pattern hair loss according to a modified Norwood/Hamilton classification scale(II to VI) were enrolled in this study. Patients were treated with multidisciplinary Korean oriental medicine treatment (herbal acupuncture, acupuncture, herb, chuna therapy) at twice a week for 6 months to 12 months. Efficacy was evaluated by patient and investigator assessment, and global photographic review. Results : Oriental medicine treatment improved scalp hair by all evaluation. Patient self assessment demonstrated that Oriental medicine treatment slowed hair loss, increased hair growth, and improvement appearance of hair. These improvements were corroborated by investigator assessments and assessments of photographs. Conclusion : Oriental medicine treatment has significant effects on the androgenetic alopecia. Longer follow up studies are needed to examine whether its effects last long enough for the patients with androgenetic alopecia.

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