• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.18 no.2
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• pp.121-127
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• 2015

Purpose: To evaluate clinical and laboratory profile of Wilson's disease (WD) in children. Methods: This cross sectional study was conducted at Bangabandhu Sheikh Mujib Medical University Hospital. Bangladesh, over a period of 3 years. One hundred consecutive children of WD between 3 to 18 years of age were evaluated. Results: Mean age was $8.5{\pm}1.5years$. Male female ratio was 2:1. Ninety-one percent of patients were Muslim and 9% Hindu. A total of 53% cases of hepatic WD presented between 5 to 10 years of age and most of the neurologic WD manifested in 10-15 years age group. Sixty-nine children presented only with hepatic manifestations, 6 only with neurological manifestations, 14 with both hepatic and neurological manifestation, 10 children was asymptomatic and 1 patient presented with psychiatric features. WD presented as chronic liver disease (CLD) in 42%, CLD with portal hypertension in 34%, acute hepatitis in 20% and fulminant hepatic failure in 4% cases. Stigmata of CLD were found in 18% patients. Keiser-Fleischser ring was found in 76% total patients. Elevated serum transaminase was found in 85% cases, prolonged prothrombin time in 59% cases and hypoalbuminaemia in 53% cases. A total of 73% patients had low serum ceruloplasmin, basal urinary copper of >$100{\mu}g/day$ was found in 81% cases and urinary copper following penicillamine challenge of >$1,200{\mu}g/day$ was found in 92% cases. Conclusion: Majority of studied WD children presented with hepatic manifestation of which 76% presented with CLD. Any child presented with jaundice after the age of 3 years should be investigated for WD.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.1
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• pp.43-49
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• 1997

This study was designed to explore whether the temperament of a child influences the physical growth. The Korean version of the Parent Questionnaire for Children developed by Thomas, Chess and Korn was applied to 395 Korean children whose ages ranged from 3 years to 7 years. Simultaneously the height and the weight were measured for each child and converted into percentile scale according to the Growth Curve and the Weight Percentile Table for the Height of Korean children. Statistical analysis was performed among 9 temperamental categories, height and weight percentiles for the age and weight percentiles for the height using the first-order partial correlation analysis, controlling for the familial mean income per month. Results showed that the more temperamentally difficult a child is, the lower weight he has when compared with the children of the same age or the same height. Although there were some differences, the tendency of the above findings was maintained both in male and female children. These results show that the temperament may influence the physical growth as well as the psychological development.

• Journal of the East Asian Society of Dietary Life
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• v.13 no.4
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• pp.284-292
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• 2003

This study was conducted to investigate the changes of dietary attitudes and behaviors in relation to the use of computers of elementary school children in Seoul. The total of 451 elementary school children, consisting of 235 females and 216 males, participated in the study. The result of domestic characteristics, dietary attitudes and behaviors, the level of the use of computers, and health-related symptoms of the subjects were achieved through the questionnaires as follows: The average height, weight, BMI and obesity-index of the participants were 149.0 cm, 42.4 kg, 19.0, -8.6, respectively. Anions subjects, 42.8％ answered their bed times were between 11~12 pm, and 82.4％ answered that they had extracurricular activities. The most desired activity as their leisure was computer works (female: 44.3％, male: 62.5％). 38.4％ of children used the computers for 1~2 hours a day and the most general usage of computers was a computer game (66.1％). The changes in dietary habits of the subjects were such as eating faster(30.2％), having lots of snacks(28.8％), eating anything at hand(26.4％), skipping breakfast due to over-sleeping(18.4％). As changes in life patterns, those in the time managements for watching T.V.(35.3％), reading(35.0％), exercising(31.9％), sleeping(27.5％), relaxing(27.5％) and other hobbies(26.4％) were observed. In conclusion, many children were being affected by the socioeconomic factors changing the environments, especially by the need for the use of computers. The rates of eating alone and skipping breakfast were getting higher in the dietary patterns of elementary school children. We found that the changes in social environments according to the heavy use of the computer were affecting on their dietary pattern. The direction and method of nutrition education had to be established for the proper understanding of the desirable dietary behaviors.

• The Journal of Korean Physical Therapy
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• v.5 no.1
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• pp.17-24
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• 1993

The purpose of this study was to find out what changes in weight bearing in the both upper extremities occurred in response to Asymmetrical Tonic Neck Reflex by rotation of head in the quadruped position. The subjects for the study were 80 children (44 male, 44 female) who were neurologically normal. They were divided into two groups $6\~7$ year olds and $8\~9$ year olds. Paired t-test was applied as a atatistical method at the 0.01 level of significance. The results of this study are as follows; 1. In the neutral position of head, there was mort weight bearing on the left hand than the right in both of the two groups(p<0.01). 2. When the head was rotated to the right or left passively, there was more weight bearing on the hand of side to which the face was rotated(p<0.01). 3. When the head was rotated to the right or left actively, there us also more weight bearing on the hand of side to which the face was rotated(p<0.01). Therefore, it is possible to un Asymmetrical Tonic Neck Reflex to increase body weight for muscle strengthening in children with weakened muscles of the upper extremities. further studies are required for confirmation of these findings.

• The Journal of Pediatrics of Korean Medicine
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• v.14 no.1
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• pp.127-136
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• 2000

The frequency of weak children, derived from constitutional and functional factors, has increased recently, but their symptoms have never been observed and analysed. A survey was conducted to evaluate and understand the characteristics of weak children. 311 children who had visited in the weak child clinic of Kyunghee Oriental Medical Hospital from January, 1999 to August, 1999, were the respondents of the Weak Child Questionnaire. They were divided into 4 groups by age and birth weight, and statistical significances were tested by one way analysis of variances and bivariate correlation analysis among groups. The results obtained were as follows: 1. Distribution of sex : male 191 cases, female 120 cases 2. The distribution of age showed the highest in $2{\sim}6$ years(45.3%), followed by $7{\sim}12$ years(31.8%), $0{\sim}1$ years(18.0%), over 13 years(4.8%) in order. There was a statistical difference of all symptoms' mean, except respiratory symptoms, among groups(p<0.01). 3. The distribution of birth weight showed the highest in $2.5{\sim}3.3kg(43.4%)$, followed by $3.3{\sim}4.1kg(39.5%)$, under 2.5kg(5.1%), over 4.lkg(2.1%) in order. There was a statistical difference of digestive symptoms' and total score mean among groups(p<0.01, p<0.05 respectively). 4. The correlation coefficient between general symptoms' mean and other symptoms´ is the highest(p<0.01). From the above results, it was suggested that general symptoms are representative of weak children's characteristics.

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.2
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• pp.139-146
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• 2006

Objective : The objective of this study is to assess the clinical effect of Gikwuibosin_tang on nocturnal enuretic children. Methods : This clinical study was carried out with 15 cases of children aged 5 to 10 years old who visited the 00 Oriental Clinic between February 2005 and August 2005 and who were diagnosed as the nocturnal enuresis. The data of present symptom and improvement progress was collected a telephone interviews with their mother. Results : The total number of children was 15, 10 of them were male and 5 were female. Sex ratio was 2:1. Patients under 6 years old were 9(60%). After the treatment of oriental medicine der $2{\sim}3$ months, 6 of the children were improved completely and 7 of them were cured quite well, 2 of them were recovered in a half way. the treatment performed very well so there's no case which were not improved at all. And a ratio of the perfect cure was 40%. Following-up survey by telephone, the treatment were performed completely for 8 of them and 4 of them were almost improved but 3 of them were not improved. And a ratio of the perfect cure was 53.3%. Conclusion : Gikwuibasin-tang is effective in the treatment of nocturnal enuretic children. Further study is needed with more cases.

• Advances in pediatric surgery
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• v.2 no.2
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• pp.110-114
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• 1996

Spontaneous gastric perforation is an important but rare cause of gastrointestinal perforation in neonates. Just over 200 cases have been reported in the literatures. In spite of recent surgical advances in its managements, mortality rate has been reported as high as 25-50%. Because of physiologic differences, immature immune mechanisms, variations in gastrointestinal flora and poor localization of perforation, a neonate with gastric perforation is at high risk. The pathogenesis is greatly debated. Five patients with spontaneous neonatal gastric perforation who were operated upon at the Department of Pediatric Surgery, Seoul National University Hospital from 1980 to 1993 were reviewed. Four patients were male and one female. The first indication of perforation was 1 day to 6 days of life. All of 5 perforations were located along the greater curvature of the stomach. The size of perforation ranged from 2 cm to 10 cm. Debridement and primary closure were performed in all patients. The operative mortality was 40%(2 of 5). The cause of perforation was not identified in all cases. Prematurity and necrotizing enterocolitis, synchronous or metachronous, were thought to he crucial prognostic factors. Earlier recognition and surgical intervention are necessary to reduce morbidity and mortality.

• Korea journal of population studies
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• v.16 no.2
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• pp.125-139
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• 1993

Korea has successfully achieved a lowered fertility level owing to the strong population control policy and effective family planning program. Along with fertility decline and decreased number of children in family, average number of household members has decreased and nontraditional households such as one person household and households composed of unrelated individuals have prolifirated, even though the absolute number of them are found minimal in Korea. However in recent years several data and survey results suggest that one person households are gradually in the increasing trend. The study aimed at investigating the real state of one person households in Korea and next analyzing the proportional distribution of one person households by a few socioeconomic characteristics, thus providing basic for eatablishing far-singhted population and social welfare policy in the future. Korea has experienced high growth rate of economy through government-led development plans starting from the 1960s. During the past three decades, Korea has shifted from the agricultural state to the industrialized one. In compliance with the economic growth, urbanization and industrialization have brought about rural-to-urban migration and a great bulk of young population migrated to urban areas, who are seeking for educational and job opportunities. Korean society has also been under drastic change in every aspect of life involving norms, tradition, and attitude, etc. Therefore, in spite of the prejudice on 'living alone' still remaining, young people gradually leave parents and home, and further form nontraditional households in urban areas. Current increase in the number of one person households is partly attributable to the increase in high female educational attainment and female participation in economic activities. As the industrial structure in Korea changes from primary into secondary and tertiary industries, job opportunities for service/sales and manufacturing are opened to young female labor force in the process of industrialization. Contrary to the formation of one person households by young people, the aged single households are composed when children in family leave one by one because of marriage, education, employment. In particular, a higher proportion of aged female single households occur in rural areas due to the mortality difference by sex. Based on the data released form the 1990 Population and Housing Census and National Fertility and Family Health Survey in 1985 and 1991, the study tried to examine the state of one person households in Korea. According to Census data, the number of one person households increased to 1, 021, 000 in 1990, comprising 9.0 percent of total households. And the survey reveal that among total 11, 540 households, 8.0 percent, 923 households, are composed of one person households. Generally, the proportion of female single households is greater than that of male ones, and a big proportion of one person households is concentrated in the 25-34 age bracket in urban areas and 65 years and more in rural areas. It is shown than one person householders in urban areas have higher educational attainment with 59.2 percent high schooling and over in 1991, Job seeking proved to be the main reason for leaving home and forming one person households. The number of young female single households with higher education and economic self-reliance are found nil and the study did not allow to analyze the causal realtionship between female education and employment and one person household formation. However more research and deep analysis on the causal facors on one person household formation using statistical method are believed to be necessary.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.2 no.1
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• pp.21-29
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• 1999

Purpose: The aims of this study are to examine clinical characteristics, patterns of medical care utilization, and factors which determine medical care utilization of elementary school children with recurrent abdominal pain (RAP), to find posssible factors influencing the onset and the course of the disorder. Method: We performed questionnaires in Kwangju on children from two primary schools from June,1 1998 to June 30 and carried out statistical analysis. Result: 1) Total number of questionnaires were 1417. 715 were male and 702 were female and the ratio of male to female was 1.02:1. Average age was 10.3 years. 2) 268 children had RAP (18.9%), boys 132 (18.4%), girls136 (19.2%). 3) The duration of the pain within 10 minutes was 68.5%. 178 children with RAP (66.3%) visited the doctor. The utilization pattern of medical facilities of the pupils with RAP; the most frequently utilized medical facility was pediatrics (35.2%) and the order ran as internal medicine (31.5%), and pharmacy (29.25). The utilization pattern of medical facilities for the older students; the utilization rate of pediatrics decreased, but internal medicine increased. The major factors affecting the selection of the medical facility were geographic accessibility, kindness of the personnel, good results and traffic convenience. 4) Symptoms which were accompanied with abdominal pain were headache (44.5%), chest pain (28.2%), dizziness (26.6%), vomiting (9%), and 119 children (44.5%) had no accompanied symptoms. 5) In 95 children (35.3%) abdominal pain, occured at postprandial time, in 55 children (20.5%) before meal and in 39 children (14.7%) at school. The highest incidence rate of RAP was observed on Monday (21.4%), and the lowest on Saturday (8.7%). 6) The most frequent involved part of the abdomen was periumbrical area (38%) and the order ran as epigastrium and suprapubic area. The most frequent characteristics of abdominal pain were burning pain (36.9%) and the order ran as dull, cramping and colicky pain. Conclusion: RAP is a frequent disease entitiy in children. Too many times children with RAP are treated by other departments instead of Pediatrics. A child has a peculiar growth and development which is different to those from an adult with advancing years. So, it is necessary to choose special medical care and an adequate medical facility.

• Childhood Kidney Diseases
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• v.17 no.2
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• pp.73-78
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• 2013

Purpose: We aimed to investigate the clinical characteristics and associated diseases in children with a horseshoe kidney and compared these data between children and adults. Method: We performed a retrospective analysis of the medical records and radiological findings of 43 patients diagnosed with a horseshoe kidney in the Busan Paik Hospital. The subjects were divided into the children's group (14 cases, age <18 years) and the adult group (29 cases, age ${\geq}18$ years). Results: The study group consisted of 17 males and 26 females with a median age of 34 years. In the children's group (14 cases), 5 subjects were male and 9 were female, with a mean age of $6.7{\pm}6.2$ years. Most of the subjects were asymptomatic and were incidentally diagnosed with horseshoe kidney during their evaluation for another disease. Among the associated diseases in the children's group, Turner syndrome was the most common (5 cases), whereas ureteropelvic junction (UPJ) stricture was observed in 2 cases (14.2%). None of the children exhibited abnormal renal function during the follow-up period. In the adult group (29 cases), 12 subjects were male and 17 were female, with a mean age of 48 years. Eighteen patients were incidentally diagnosed with horseshoe kidney during their evaluation for another disease, and 11 patients had hematuria or abdominal pain due to renal stones. Among the associated diseases in the adult group, Turner syndrome was the most common (5 cases), and UPJ stricture was observed in 5 cases; the other accompanying diseases included hydronephrosis and overactive bladder. Six patients exhibited decreased renal function (serum creatinine level >1.5) during the follow-up period. Conclusion: Horseshoe kidney is usually diagnosed incidentally in both children and adults. In the present study, we noted that Turner syndrome was the most common associated disease in children. In addition, most children were asymptomatic but had a high risk of urologic complications after the transition to adulthood. Therefore, children with horseshoe kidney require continuous follow-up.