• Title/Summary/Keyword: maintenance system

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Influence of Interferon-${\tau}$ on the Production of Prostaglandins, Cyclooxygenase-2 Expression In Vitro and Release of Progesterone in Bovine Endometrial Cells

  • Lee, Ji-Eun;Lee, Yong-Seung;Yoo, Han-Jun;Lee, Kyoung-Jin;Park, Joung-Jun;Cheong, Hee-Tae;Yang, Boo-Keun;Park, Choon-Keun
    • Journal of Embryo Transfer
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    • v.27 no.4
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    • pp.245-252
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    • 2012
  • The purpose of the present study was to investigate the effect of IFN-${\tau}$ on prostaglandin synthesis, cyclooxygenase-2 (COX-2) gene expression in vitro and concentration of progesterone (P4) in endometrial cells. Epithelial and stromal cells cultured in vitro were isolated from bovine endometrium and stimulated with increasing doses of IFN-${\tau}$ (0, 0.02, 0.2 and 2 ug/ml). Human chorionic gonadotropin (hCG, 1.5 IU/ml) was used as a positive control. Prostaglandin $E_2$ and $F_{2{\alpha}}$ levels in the culture media were analyzed by enzyme immunoassays and total RNA was extracted from the cells for RT-PCR. P4 concentrations of blood samples were assayed by chemiluminescent immuno assays system. In epithelial cells, COX-2 gene expression was increased in the presence of IFN-${\tau}$ (p<0.05), but it was not significantly different in all groups of stromal cells except for 2 ug/ml IFN-${\tau}$ group (p<0.05). Although IFN-${\tau}$ did not affect $PGE_2$ and $PGF_{2{\alpha}}$ production in epithelial cells, it decreased $PGE_2$ and $PGF_{2{\alpha}}$ production significantly in stromal cells (p<0.05). In vivo experiment, blood concentration of P4 was significantly increased after addition of IFN-${\tau}$ (1 ug/ml). The results indicate that PG production was mediated by COX-2 expression in stromal cells but it was not affected in epithelial cells and this suggest that treatment of IFN-${\tau}$ could improve the implantation environment of uterine by maintenance of high P4 concentration.

Adina rubella Phytocoena in Jeju Island, Korea (제주도 하천의 중대가리나무 식생)

  • Choi, Byoung-Ki;Ryu, Tae-Bok;Kim, Jong-Won
    • Korean Journal of Ecology and Environment
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    • v.48 no.1
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    • pp.68-76
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    • 2015
  • There is no willow riparian vegetation in Jeju Island, Korea. Instead, a genetically-isolated population of Adina rubella is found in some parts of the riparian system. We describe its syntaxonomy and synecology. A total of 27 phytosociological relev$\acute{e}$s were collected, 11 relev$\acute{e}$s from 91 sites and 16 relev$\acute{e}$s from the previously published relevant materials. Data were analyzed by traditional Braun-Blanquet method and multivariate PCoA (Principal coordinates analysis). New syntaxa are distinguished, Adinion rubellae all. nov. and its type association Tripogono-Adinetum rubellae ass. nov. with two subassociations, typicum and rhododendretosum poukhanensae. Adino-Rhododendretum poukhanensae Itow et al. 1993 was discarded owing to mismatch of syntaxonomy and syngeography of Adina and Rhododendron phytocoena. The alliance Adinion is Jeju's regional and partly ombrotrophic vegetation occurring in pothole and rock crevice where are independent on ground-water table. We also suggest a revised alliance, Rhododendrion poukhanensae Lee 2004 ex. hoc loco in Korean peninsula, as a corresponding syntaxon to Adinion, which completely differs from Phragmito-Salicion. Finally we pointed out that Adina phytocoena requiring an absolutely monitoring has been threatened by river maintenance project of local government.

A Study on the Activation for the Mobile App Services of Local Government (지방자치단체의 모바일 앱 서비스 이용 활성화 방안에 관한 연구: 부산광역시를 중심으로)

  • Jung, Su Hee;Hong, Soon Goo;Cha, Yoon Sook;Kim, Jong Weon
    • Journal of Korea Society of Industrial Information Systems
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    • v.18 no.2
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    • pp.71-83
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    • 2013
  • Because of rapid advance of wireless Internet-related technology and fast diffusion of Smart phone, a variety of mobile applications through domestic and foreign app stores have been made and used. Under the recognition of current trend, both central government and local government have developed and provided public mobile app in order to accomplish the mobile e-government. However, public mobile app is not popular in spite of vast investment for its development and service. This study investigated current issues and problems of public mobile app in public service, management, and technology aspects. To do so, this study categorized the interested people of public mobile app into users, providers, and developers, and conducted deep interviews to them. Based on the interview results, the study suggested the following recommendations for the activating tools of public mobile app: providing user-customized information, fruitfulness of public information management, maintenance of management system for public mobile app service, user-friendly promotion appropriate in mobile environment, public mobile app development based on e-government standard framework, etc.. This study may provide the researchers with the successive study guidelines in mobile e-government and public mobile app fields. Also, the study may help the practitioners to make effective decisions on polices and strategies for mobile e-government of local government.

Three-dimensional finite element analysis for influence of marginal bone resorption on stress distribution in internal conical joint type implant fixture (변연골 흡수가 내측연결 임플란트 매식체의 응력분포에 미치는 영향)

  • Yun, Mi-Jung;Yoon, Min-Chul;Eom, Tae-Gwan;Huh, Jung-Bo;Jeong, Chang-Mo
    • The Journal of Korean Academy of Prosthodontics
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    • v.50 no.2
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    • pp.99-105
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    • 2012
  • Purpose: The change of the marginal bone around dental implants have significance not only for the functional maintenance but also for the esthetic success of the implant. The purpose of this study was to investigate the load transfer of internal conical joint type implant according to marginal bone resorption by using the three-dimensional finite element analysis model. Materials and methods: The internal conical joint type system was selected as an experimental model. Finite element models of bone/implant/prosthesis complex were constructed. A load of 300 N was applied vertically beside 3 mm of implant axis. Results: The pattern of stress distribution according to marginal bone resorption was similar. The maximum equivalent stress of implant was increase according to marginal bone resorption and the largest maximum equivalent stress was shown at model of 1 mm marginal bone resorption. Although marginal bone loss more than 1mm was occurred increasing of stress, the width of the stress increase was decreasing. Conclusion: According to these results, the exposure of thin neck portion of internal conical joint type implant is most important factor in stress increasing.

The Experience on Intake Estimation and Internal Dose Assessment by Inhalation of Iodine-131 at Korean Nuclear Power Plants (국내 원전에서 $^{131}I$ 내부 흡입 에 따른 섭취량 산정과 내부피폭 방사선량 평가 경험 몇 개선방향에 대한 연구)

  • Kim, Hee-Geun;Kong, Tae-Young
    • Journal of Radiation Protection and Research
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    • v.34 no.3
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    • pp.129-136
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    • 2009
  • During the maintenance period at Korean nuclear power plants, internal exposure of radiation workers occurred by the inhalation of $^{131}I$ released to the reactor building when primary system opened. The internal radioactivity of radiation workers contaminated by $^{131}I$ was measured using a whole body counter. Intake estimation and the calculation of committed effective dose were also conducted conforming to the guidance of internal dose assessments from publications of International Commission on Radiological Protection. Because the uptake and excretion of $^{131}I$ in a body occur quickly and $^{131}I$ is accumulated in the thyroid gland, the estimated intakes showed differences depending on the counting time after intake. In addition, since ICRP publications do not provide the intake retention fraction (IRF) for whole body of $^{131}I$, the IRF for thyroid was substitutionally used to calculate the intake and subsequently this caused more error in intake estimation. Thus, intake estimation and the calculation of committed effective dose were conducted by manual calculation. In this study, the IRF for whole body was also calculated newly and was verified. During this process, the estimated intake and committed effective dose were reviewed and compared using several computer codes for internal dosimetry.

When Dose Losses of Maternal Lymphocytes Response to Trophoblast Antigen or Alloantigen Occur in Women with a History of Recurrent Spontaneous Abortion? (반복유산을 경험한 환자에서 임신중 태반항원과 동종항원에 노출된 모체 림프구면역반응은 언제부터 소실되나?)

  • Choi, Bum-Chae;Hill, Joseph A.
    • Clinical and Experimental Reproductive Medicine
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    • v.25 no.2
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    • pp.115-122
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    • 1998
  • The maintenance of a viable pregnancy has long been viewed as an immunological paradox. The deveolping embryo and trophoblast are immunologically foreign to the maternal immune system due to their maternally inherited genes products and tissue-specific differentiation antigens (Hill & Anderson, 1988). Therefore, speculation has arisen that spontaneous abortion may be caused by impaired maternal immune tolerance to the semiallogenic conceptus (Hill, 1990). Loss of recall antigen has been reported in immunosuppressed transplant recipients and is associated with graft survival (Muluk et al., 1991; Schulik et al., 1994). Progesterone $(10^{-5}M)$ has immunosuppressive capabilities (Szekeres-Bartho et al., 1985). Previous study showed that fertile women, but not women with unexplained recurrent abortion (URA), lose their immune response to recall antigens when pregnant (Bermas & Hill, 1997). Therefore, we hypothesized that immunosuppressive doses of progesterone may affect proliferative response of lymphocytes to trophoblast antigen and alloantigen. Proliferative responses using $^3H$-thymidine ($^3H$-TdR) incorporation of peripheral blood mononuclear cells (PBMCs) to the irradiated allogeneic periperal blood mononuclear cells as alloantigen, trophoblast extract and Flu as recall antigen, and PHA as mitogen were serially checked in 9 women who had experienced unexplained recurrent miscarriage. Progesterone vaginal suppositories (100mg b.i.d; Utrogestan, Organon) beginning 3 days after ovulation were given to 9 women with unexplained RSA who had prior evidence of Th1 immunity to trophoblast. We checked proliferation responses to conception cycle before and after progesterone supplementation once a week through the first 7 weeks of pregnancy. All patients of alloantigen and PHA had a positive proliferation response that occmed in the baseline phase. But 4 out of 9 patients (44.4%) of trophoblast antigen and Flu antigen had a positive proliferative response. The suppression of proliferation response to each antigen were started after proliferative phase and during pregnancy cycles. Our data demonstrated that since in vivo progesterone treated PBMCs suppressed more T-lymphocyte activation and $^3H$-TdR incorporation compare to PBMCs, which are not influenced by progesterone. This data suggested that it might be influenced by immunosuppressive effect of progesterone. In conclusion, progesterone may play an important immunological role in regulating local immune response in the fetal-placental unit. Furthermore, in the 9 women given progesterone during a conception cycle, Only two (22%) repeat pregnancy losses occured in these 9 women despite loss of antigen responsiveness (one chemical pregnancy loss and one loss at 8 weeks of growth which was karyotyped as a Trisomy 4). These finding suggested that pregnancy loss due to fetal aneuploidy is not associated with immunological phenomena.

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A Study on Implications of the naval Strategy in West Germany and Future Direction of Korean Navy (냉전기 서독해군 전략의 시사점과 향후 대한민국 해군의 방향성에 관한 연구)

  • Shin, Hong-Jung
    • Strategy21
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    • s.46
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    • pp.159-204
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    • 2020
  • This study is written to bring the proposal forward for the direction of south korean naval force. The political situation and the circumstance of the world, especially in the area of Pacific Ocean, are changing very rapidly. North Korea has been always the conventional existing intimidator for South Korea since the 6·25-War. Additionally, the strengthening movements of the national defense, which is easily noticed from China and Russia, is also an other part of intimidating countries against South Korea. Those three mentioned countries are continually developing the asymmetrical warfare systems, for example a strategic nuclear weapon. Since the Obama Administration, the Asia-Pacific Rebalancing-Strategy has been changed as an East Asian foreign policy. Nowadays, Trump Administration renamed the 'United States Pacific-Command' to 'United States Indo-Pacific Command'. The purpose of this is not only letting India to participate in american alliance, but also reducing an economic burden, which is often mentioned in USA. West Germany was located in the very similar geopolitical position during the Cold War just like South Korea these days. And that's why the strategy of West German Navy is worthy of notice for south korean naval force to decide its suitable strategy. Most of all, the two most important things to refer to this study are the plan to expand naval air force and the realistic political stand for us to take it. In conclusion, I laid an emphasis on maintenance of 'green-water-navy'. instead of selecting the strategy as a 'blue-water-navy'. The reason I would like to say, is that south korean navy is not available to hold the unnecessary war potential, just like Aircraft-Carrier. However, this is not meaning to let the expansion of naval force carelessly. We must search the best solution in order to maintain the firm peace within the situation. To fulfill this concept, it is mostly very important to maintain the stream of laying down a keel of destroyers, submarines and air-defense-missile, as well as the hight-tech software system, taking a survey of 4th industrial revolution. Research and development for the best solution of future aircraft by south korean navy is likewise necessary. Besides, we must also set the international diplomatic flexibly. As well as maintaining the relationship with US Forces, it is also very important to improve the relationship with other potential allied nation.

Seasonal Earthworm Casting Activity on Korean Golf Courses (골프장에서 지렁이 분변토 발생의 계절적 변화)

  • Shin, Chong Chang;Kim, Jong Kyung;Hong, Yong;Kim, Young Sub;Kim, Jin Ho;Park, Dae Sup;Lee, Dong Woon
    • Weed & Turfgrass Science
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    • v.4 no.4
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    • pp.368-375
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    • 2015
  • Earthworm cast occurred in surface of turfgrass in golf courses which affect turfgrass maintenance and golf play. In this study several survey of seasonal fluctuation of earthworm cast in different golf courses (Anseong, Gapyeong, Gunpo and Yongin in Gyeonggi province, and Geumjeong in Busan) was done. A number of earthworm, soil temperature and moisture of detection site of earthworm cast in each golf course were also done. Cast occurred in different golf courses are found mostly from April to November on turf surface and the cast number varied in different month as well as in golf courses. In the same golf courses, a number of detected cast was difference from individual sites. A number of cast and earthworm was correlated. Also, in higher soil moisture showed the higher cast density in different golf courses. Soil temperature and moisture of detecting cast ranging from $2.1^{\circ}C$ to $33.1^{\circ}C$ and 4.9 to 44.1%, respectively. In case of cast, soil temperature level lies in between $10-15^{\circ}C$ where the highest soil moisture was 25%.

A Social Historical Study on Security System of Goryo Period (고려시대(高麗時代) 시위제도(侍衛制度)에 관한 사적고찰(史的考察))

  • Kim, Chang-Ho;Min, Jae-Ki
    • Korean Security Journal
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    • no.15
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    • pp.107-128
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    • 2008
  • It was started that Shiwe-goon was organized from Shilla-end to Goryeo foundation a country in powerful families existence merely royal household by stably plan means in the reign of Taejo. Generally Shiwe-goon was dutie king' personal danger of protection. Shiwe-goon was organized castle of guarding, stand by king and royal household side armed strength to going on a trip and general armed-organization was collapsed for Goryeo-end continued existence. Goryeo era of Shiwe-organization was divided central army and region army. Two-goon(Eungyang-goon, Yongho-goon) was undertaken king of Shiwe army and six-we(Chunwoo-we, Geumoh-we, Gammoon-we, Jeoawoo-we, Shinoh-we, Hongwe-we) was undertaked capital of guard and the border of defense duty. Central army of commanders was called Sangjanggoon, Daejanggoon. Sangjanggoon and Daejanggoon was discussed military officer of conference apparatus in Jungbang. Jungbang was got afterward Mooshinjungbeon happened military of statesman grasping political power with authority a main stay. Mooshinjungkwen era was appeared modernistic mean of privately guarding organization in Dobang and Naedobang. According as Shiwe-organization was charged military organization as a part of sovereign power and grasping strength of authority- maintenance for security and guarding duty. As a conclusion, national sovereign of guard was achieved not only personal life and body guard protection but also country of welfare protection in country-welfare dimension an inch of non-error. Also national sovereign of guard was considered guarding apparatus of allowance the largest duty and country-welfare direct connection with actual fact recognition in constancy effort.

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Simulation of Remote Field Scanner for Defect Evaluation of Water Wall Tube Within the Fluidized Bed Boiler (유동층보일러 수냉벽튜브 결함평가를 위한 원격자장 스캐너 시뮬레이션에 관한 연구)

  • Gil, Doo-Song;Jung, Gye-Jo;Seo, Jung-Seok;Kim, Hak-Joon;Kwon, Chan-Wool
    • KEPCO Journal on Electric Power and Energy
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    • v.6 no.2
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    • pp.145-150
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    • 2020
  • Water wall tube is one of the major factors consisting of a fluidized bed boiler and it plays very important role for the generation of electricity within the boiler. But these water wall tubes within the fluidized bed boiler are subject to the ware and corrosion caused by the high temperature gas and the flowing medium. If water leak is occurred, the secondary damage by the water leak will occur. As a result of that, the power generation efficiency decreases noticeably. Therefore, the maintenance of the water wall tube is very important. In this study, we designed a exciter sensor based on simulation and composed a remote field eddy current system for the defect evaluation of the outer water wall tube. Starting from the shape design of exciter, we conducted simulations for various design factors such as the water wall tube size, material, frequency, lift-off and so on. Based on the results, we designed the optimum exciter sensor for the water wall tube test within the fluidized bed boiler.